Position in ACRS
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$1,483,638
-$244,743 QoQ
Shares Held
395,637
-31.1% QoQ
Ownership
0.283%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2020
18 quarters on record
Voting authority
Sole 98.76149096267538.ToString("F0")%
Shared 0.ToString("F0")%
None 1.2385090373246184.ToString("F0")%
Common Shares in ACRS Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. ACRS ranks #176 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in ACRS
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18 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $1,483,638 | 395,637 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $1,728,381 | 574,213 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $699,403 | 368,107 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,064,517 | 749,660 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $1,255,003 | 820,264 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $2,081,389 | 839,270 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $1,044,103 | 907,916 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $1,224,379 | 1,113,072 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $1,648,723 | 1,329,616 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $1,536,634 | 1,463,461 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $177,415 | 25,900 | Shares | Sole | 2023-11-14 | |
| 2023-03-31 | $683,135 | 84,442 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $168,525 | 10,700 | Shares | Sole | 2023-02-14 | |
| 2021-12-31 | $189,659 | 13,044 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $1,976,904 | 109,828 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $6,590,303 | 375,302 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $4,386,715 | 174,076 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $557,015 | 86,092 | Shares | Sole | 2021-02-16 | |
| No filing history on record for this holder in this stock. | ||||||