Position in ACRS
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$703,929
-$779,709 QoQ
Shares Held
133,068
-66.4% QoQ
Ownership
0.090%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#64
of 149 holders
Holding Since
Dec 2020
19 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in ACRS Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. ACRS ranks #223 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in ACRS
Export CSV
19 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $703,929 | 133,068 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $1,483,638 | 395,637 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $1,728,381 | 574,213 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $699,403 | 368,107 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,064,517 | 749,660 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $1,255,003 | 820,264 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $2,081,389 | 839,270 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $1,044,103 | 907,916 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $1,224,379 | 1,113,072 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $1,648,723 | 1,329,616 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $1,536,634 | 1,463,461 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $177,415 | 25,900 | Shares | Sole | 2023-11-14 | |
| 2023-03-31 | $683,135 | 84,442 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $168,525 | 10,700 | Shares | Sole | 2023-02-14 | |
| 2021-12-31 | $189,659 | 13,044 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $1,976,904 | 109,828 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $6,590,303 | 375,302 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $4,386,715 | 174,076 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $557,015 | 86,092 | Shares | Sole | 2021-02-16 | |
| No filing history on record for this holder in this stock. | ||||||