ACRS · Aclaris Therapeutics, Inc.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vested on June 5, 2026.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vested on June 5, 2026.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vested on June 5, 2026.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vested on June 5, 2026.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vested on June 5, 2026.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vested on June 5, 2026.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares subject to this stock option will vest in twelve equal monthly installments commencing on July 4, 2026, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2025 Equity Incentive Plan, or the Plan) through each such vesting date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units will vest in one installment on June 4, 2027, subject to the Reporting Person's Continuous Service (as defined in the Plan) as of such date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units will vest in one installment on June 4, 2027, subject to the Reporting Person's Continuous Service (as defined in the Plan) as of such date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units will vest in one installment on June 4, 2027, subject to the Reporting Person's Continuous Service (as defined in the Plan) as of such date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units will vest in one installment on June 4, 2027, subject to the Reporting Person's Continuous Service (as defined in the Plan) as of such date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

The shares subject to this stock option will vest in twelve equal monthly installments commencing on July 4, 2026, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2025 Equity Incentive Plan, or the Plan) through each such vesting date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

The shares subject to this stock option will vest in twelve equal monthly installments commencing on July 4, 2026, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2025 Equity Incentive Plan, or the Plan) through each such vesting date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units will vest in one installment on June 4, 2027, subject to the Reporting Person's Continuous Service (as defined in the Plan) as of such date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

The shares subject to this stock option will vest in twelve equal monthly installments commencing on July 4, 2026, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2025 Equity Incentive Plan, or the Plan) through each such vesting date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

The shares subject to this stock option will vest in twelve equal monthly installments commencing on July 4, 2026, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2025 Equity Incentive Plan, or the Plan) through each such vesting date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

The shares subject to this stock option will vest in twelve equal monthly installments commencing on July 4, 2026, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2025 Equity Incentive Plan, or the Plan) through each such vesting date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units will vest in one installment on June 4, 2027, subject to the Reporting Person's Continuous Service (as defined in the Plan) as of such date.

This grant was made pursuant to the issuer's tenth amended and restated non-employee director compensation policy.

Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of May 1, 2025, subject to the Continuous Service (as defined in the Issuer's 2024 Inducement Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer.

The transaction reported represents the withholding of shares by the issuer to satisfy the Reporting Person's tax withholding obligations in connection with the vesting and settlement of restricted stock units described in this Form 4.

BML Capital Management, LLC ("BML Capital") serves as the general partner of BML Investment Partners, L.P., a Delaware limited partnership (the "Fund"), which is the direct owner of the subject shares. Mr. Leonard is the managing member of BML Capital, and exercises investment and voting control over the subject shares. Accordingly, shares owned directly by the Fund may be regarded as being beneficially owned by Mr. Leonard. Notwithstanding, Mr. Leonard disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein.

The transaction reported represents the withholding of shares by the issuer to satisfy the Reporting Person's tax withholding obligations in connection with the vesting and settlement of restricted stock units described in this Form 4.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal annual installments beginning on March 1, 2023, subject to the Continuous Service of the Reporting Person (as defined in the Plan) as of the applicable vesting date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The transaction reported represents the withholding of shares by the issuer to satisfy the Reporting Person's tax withholding obligations in connection with the vesting and settlement of restricted stock units described in this Form 4.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The transaction reported represents the withholding of shares by the issuer to satisfy the Reporting Person's tax withholding obligations in connection with the vesting and settlement of restricted stock units described in this Form 4.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 3, 2025, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 3, 2025, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The transaction reported represents the withholding of shares by the issuer to satisfy the Reporting Person's tax withholding obligations in connection with the vesting and settlement of restricted stock units described in this Form 4.

Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer.

Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 3, 2025, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 3, 2025, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Exercisable with respect to 25% of the shares subject to the option vesting in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Exercisable with respect to 25% of the shares subject to the option vesting in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Exercisable with respect to 25% of the shares subject to the option vesting in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.

Each restricted stock unit represents a contingent right to receive one share of common stock of the issuer.

The shares underlying these restricted stock units vest in four equal installments on the first, second, third and fourth anniversaries of February 2, 2026, subject to the Continuous Service (as defined in the Plan) of the Reporting Person as of each such date.