TWO SIGMA INVESTMENTS, LP
Position in ARCT — Arcturus Therapeutics Holdings Inc.
CIK 1179392
NEW YORK, NY
Position in ARCT
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$7,332,440
-$1,018,932 QoQ
Shares Held
1,091,137
+0.9% QoQ
Ownership
3.84%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#7
of 133 holders
Holding Since
Mar 2020
21 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in ARCT Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,273,664,878 across 342 Biotechnology names. ARCT ranks #96 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in ARCT
Export CSV
21 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $7,332,440 | 1,091,137 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $8,351,372 | 1,081,784 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $3,351,185 | 546,686 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $1,644,306 | 89,219 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,123,569 | 86,362 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $395,589 | 37,355 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $467,693 | 27,560 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $397,587 | 17,130 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $324,293 | 13,318 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $481,560 | 14,260 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $809,059 | 25,660 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $525,308 | 20,560 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $575,320 | 20,060 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $274,696 | 11,460 | Shares | Sole | 2023-05-15 | |
| 2021-09-30 | $355,674 | 7,444 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $11,014,683 | 325,493 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $16,218,633 | 392,703 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $7,074,844 | 163,090 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $11,854,042 | 276,318 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $4,334,948 | 92,746 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $313,140 | 23,042 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||