8-K - ARE - Equibles

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): July 26, 2021

ALEXANDRIA REAL ESTATE EQUITIES, INC.

(Exact name of registrant as specified in its charter)

Maryland	1-12993	95-4502084
(State or other jurisdiction of<br>incorporation)	(Commission File Number)	(I.R.S. Employer Identification No.)

26 North Euclid Avenue, Pasadena, California 91101

(Address of principal executive offices) (Zip code)

Registrant’s telephone number, including area code: (626) 578-0777

N/A

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4 (c) under the Exchange Act (17 CFR 240.13e-4 (c))

Securities registered pursuant to Section 12(b) of the Exchange Act:

Title of each class	Trading Symbol(s)	Name of each exchange on which registered
Common Stock, $.01 par value per share	ARE	New York Stock Exchange

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02. Results of Operations and Financial Condition.

On July 26, 2021, Alexandria Real Estate Equities, Inc. (the “Company”) issued a press release entitled “Alexandria Real Estate Equities, Inc. Reports Second Quarter Ended June 30, 2021 Financial and Operating Results.” The press release referred to certain supplemental information that is available on the Company’s website at www.are.com. A copy of the press release and supplemental information are attached hereto as Exhibit 99.1.

The information contained in this Item 2.02, including the exhibit referenced herein, is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section. Such information shall not be incorporated by reference into any filing under the Securities Act of 1933, as amended (the “Securities Act”), or the Exchange Act, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

99.1 Alexandria Real Estate Equities, Inc.’s Earnings Press Release and Supplemental Information for the Second Quarter Ended June 30, 2021

104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

Forward-Looking Statements

This current report on Form 8-K contains forward-looking statements within the meaning of Section 27A of the Securities Act, and Section 21E of the Exchange Act. These statements include words such as “forecast,” “guidance,” “projects,” “estimates,” “anticipates,” “goals,” “believes,” “expects,” “intends,” “may,” “plans,” “seeks,” “should,” or “will,” or the negative of these words or similar words. Forward-looking statements involve certain risks and uncertainties, and actual results may differ materially from those discussed in each such statement. A number of important factors could cause actual results to differ materially from those included within or contemplated by the forward-looking statements, including, but not limited to, the factors described in the Company’s filings with the Securities and Exchange Commission, including the Company’s most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q. The Company does not undertake any responsibility to update any of these factors or to announce publicly any revisions to any of the forward-looking statements contained in this or any other document, whether as a result of new information, future events, or otherwise.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	ALEXANDRIA REAL ESTATE EQUITIES, INC.
July 26, 2021	By:	/s/ Joel S. Marcus
		Joel S. Marcus
		Executive Chairman
	By:	/s/ Stephen A. Richardson
		Stephen A. Richardson
		Co-Chief Executive Officer
	By:	/s/ Peter M. Moglia
		Peter M. Moglia
		Co-Chief Executive Officer and <br>Co-Chief Investment Officer
	By:	/s/ Dean A. Shigenaga
		Dean A. Shigenaga
		President and Chief Financial Officer

Document

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021

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(1)Source: Centers for Disease Control and Prevention/National Center for Health Statistics, “Provisional Drug Overdose Death Counts: Dashboard,” accessed July 2021.

Alexandria Real Estate Equities, Inc. All Rights Reserved. ©2021	ii

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(1)Represents credit rating levels from Moody’s Investors Service and S&P Global Ratings for publicly traded U.S. REITs (excluding mortgage REITs), from Bloomberg Professional Services as of June 30, 2021.

(2)Refer to “Annual rental revenue” and “Investment-grade or publicly traded large cap tenants” in the “Definitions and reconciliations” of our Supplemental Information for additional details.

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(1)Liquidity as of June 30, 2021. Refer to “Key credit metrics” of our Supplemental Information for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. ©2021	vii

(2)A credit rating is not a recommendation to buy, sell, or hold securities and may be subject to revision or withdrawal at any time.

(3)As of June 30, 2021. Refer to “Key credit metrics” of our Supplemental Information for additional details.

(4)Quarter annualized.

(5)As of June 30, 2021.

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(1)15 projects have been certified and another 32 projects are in process targeting WELL or Fitwel certification.

(2)Source: Barron’s, “The 10 Most Sustainable REITs, According to Calvert,” February 19, 2021.

(3)Relative to a 2015 baseline for buildings in operation that Alexandria directly manages.

(4)For buildings in operation that Alexandria indirectly and directly manages.

(5)Reflects sum of annual like-for-like progress from 2015 to 2020.

(6)Reflects progress for all buildings in operation in 2020 that Alexandria indirectly and directly manages.

Alexandria Real Estate Equities, Inc. All Rights Reserved. ©2021	x
Table of Contents
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June 30, 2021		EARNINGS PRESS RELEASE	Page	Page
---	---	---	---
Second Quarter Ended June 30, 2021, Financial and Operating Results	1	Earnings Call Information and About the Company	7
Acquisitions	4	Consolidated Statements of Operations	8
Dispositions and Salesof Partial Interest	5	Consolidated Balance Sheets	9
Guidance	6	Funds From Operations and Funds From Operations per Share	10
SUPPLEMENTAL INFORMATION	Page		Page
Company Profile	13	External Growth / Investments in Real Estate
Investor Information	14	Investments in Real Estate	32
Financial and Asset Base Highlights	15	New Class A Development and Redevelopment Properties:
High-Quality, Diverse, and Innovative Tenants	17	Recent Deliveries	34
Class A Properties in AAA Locations	18	Current Projects	36
Occupancy	19	Summary of Pipeline	40
Internal Growth		Construction Spending	43
Key Operating Metrics	20	Joint Venture Financial Information	44
Same Property Performance	21	Balance Sheet Management
Leasing Activity	22	Investments	46
Contractual Lease Expirations	23	Key Credit Metrics	47
Top 20 Tenants	24	Summary of Debt	48
Summary of Properties and Occupancy	25	Definitions and Reconciliations
Property Listing	26	Definitions and Reconciliations	51

This document is not an offer to sell or a solicitation to buy securities of Alexandria Real Estate Equities, Inc. Any offers to sell or solicitations to buy our securities shall be made only by means of a prospectus approved for that purpose. Unless otherwise indicated, the “Company,” “Alexandria,” “ARE,” “we,” “us,” and “our” refer to Alexandria Real Estate Equities, Inc. and our consolidated subsidiaries.

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Alexandria Real Estate Equities, Inc., at the Vanguard of Providing High-Quality Office/Laboratory Space to Meet Historic-High Demand from the Life Science Industry, Reports:

2Q21 and 1H21 Net Income per Share – Diluted of $2.61 and $2.74, respectively;

2Q21 and 1H21 FFO per Share – Diluted, As Adjusted, of $1.93 and $3.84, respectively

PASADENA, Calif. – July 26, 2021 – Alexandria Real Estate Equities, Inc. (NYSE:ARE) announced financial and operating results for the second quarter ended June 30, 2021.

Key highlights
Operating results	2Q21			2Q20		1H21			1H20
Total revenues:
In millions	$	509.6		$	437.0	$	989.5		$	876.9
Growth	16.6		%			12.8		%
Net income attributable to Alexandria’s common stockholders – diluted
In millions	$	380.6		$	226.6	$	388.5		$	244.8
Per share	$	2.61		$	1.82	$	2.74		$	1.99
Funds from operations attributable to Alexandria’s common stockholders – diluted, as adjusted
In millions	$	282.3		$	225.0	$	545.2		$	446.4
Per share	$	1.93		$	1.81	$	3.84		$	3.63

Six-time Nareit Investor CARE Gold Award winner

2021 recipient of the Nareit Investor CARE (Communications and Reporting Excellence) Gold Award in the Large Cap Equity REIT category as the best-in-class REIT delivering transparency, quality, and efficient communications and reporting to the investment community. This represents our fourth consecutive Nareit Investor CARE Gold Award, and our sixth Gold Award over the last seven years.

Historic leasing activity and rental rate growth; continued strong net operating income and internal growth

•During 2Q21, historic demand for our high-quality office/laboratory space translated into 1.9 million RSF of leasing activity, representing the highest leasing activity in a single quarter and the second highest rental rate growth in Company history.

•Continued strong leasing activity and rental rate growth during 2Q21 and 1H21 over expiring rates on renewed and re-leased space:

	2Q21	1H21
Total leasing activity – RSF	1,933,838	3,611,497
Leasing of development and redevelopment space – RSF	256,328	1,045,301
Lease renewals and re-leasing of space:
RSF (included in total leasing activity above)	1,472,713	1,994,538
Rental rate increases	42.4%	40.7%
Rental rate increases (cash basis)	25.4%	23.3%

Historic leasing activity and rental rate growth; continued strong net operating income and internal growth (continued)

•Net operating income (cash basis) of $1.3 billion for 2Q21 annualized, up $194.4 million, or 17.6%, compared to 2Q20 annualized.

•95% of our leases contain contractual annual rent escalations approximating 3%.

•Same property net operating income growth:

•3.7% and 7.8% (cash basis) for 2Q21 over 2Q20.

•4.4% and 7.4% (cash basis) for 1H21 over 1H20.

A REIT industry-leading high-quality tenant roster with high-quality revenues and cash flows, strong margins, and operational excellence

Percentage of annual rental revenue in effect from investment-grade or publicly traded large cap tenants	53	%
Occupancy of operating properties in North America	94.3	%	(1)
Operating margin	72	%
Adjusted EBITDA margin	69	%
Weighted-average remaining lease term:
All tenants	7.5		years
Top 20 tenants	11.1		years

(1)Includes 1.4 million RSF, or 3.8%, of vacancy at recently acquired properties in our North America markets, representing lease-up opportunities that are expected to provide incremental annual rental revenues in excess of $55 million. Approximately 35% of the vacant 1.4 million RSF is currently under leased/negotiating, with occupancy expected primarily over the next two quarters. Excluding these acquired vacancies, occupancy of operating properties in North America was 98.1% as of June 30, 2021. Refer to “Occupancy” of our Supplemental Information for additional details.

Strong and flexible balance sheet with significant liquidity

•Investment-grade credit ratings ranked in the top 10% among all publicly traded U.S. REITs as of June 30, 2021.

•Net debt and preferred stock to Adjusted EBITDA of 5.8x for 2Q21 annualized.

•Fixed-charge coverage ratio of 4.9x for 2Q21 annualized.

•$4.5 billion of liquidity as of June 30, 2021.

Continued dividend strategy to share growth in cash flows with stockholders

Common stock dividend declared for 2Q21 of $1.12 per common share, aggregating $4.36 per common share for the twelve months ended June 30, 2021, up 24 cents, or 6%, over the twelve months ended June 30, 2020. Our FFO payout ratio of 60% for the three months ended June 30, 2021, allows us to continue to share growth in cash flows from operating activities with our stockholders while also retaining a significant portion for reinvestment.

Sustained strength in tenant collections

•Tenant collections remain consistently high, with 99.4% of July 2021 billings collected as of the date of this release.

•As of June 30, 2021, our tenant receivables balance was $6.7 million, representing our lowest balance since 2012.

Leasing activity of development and redevelopment projects

We continue to execute our unique and differentiated life science strategy at an accelerated pace and expand our collaborative campuses and asset base in each of our key life science cluster submarkets, and we remain strategically positioned to take maximum advantage of historic tenant demand. Demand for our value-creation development and redevelopment projects of high-quality office/laboratory space, as well as continued operational excellence at our world-class, sophisticated laboratory facilities and strong execution by our team, has translated into record leasing activity. The following table provides leasing activity of our development and redevelopment projects:

Leased RSF		In-Process RSF(1)
2020	1H21	As of July 26, 2021
1.0 million	1.0 million	3.0 million

(1) Represents in-process leasing activity on near-term value-creation development and redevelopment projects that are expected to commence vertical construction in 2021/2022. Includes 2.2 million RSF related to leases under negotiation/executed letters of intent and 0.8 million RSF related to letters of intent under negotiation.

Value-creation development and redevelopment projects are expected to generate significant growth in rental revenues and cash flows

Under Construction		Projects Expected to Commence<br>Construction in 2021/2022		Incremental Projected<br>Annual Rental Revenues
3.4 million RSF		3.6 million RSF		>$545 million
33 Properties	+	19 Properties	=
80% Leased/Negotiating		89% Leased/Negotiating

Delivery of fully leased value-creation projects

•During 2Q21, we placed into service development and redevelopment projects aggregating 755,565 RSF that are 100% leased across five submarkets.

•Annual net operating income (cash basis) is expected to increase by $49 million upon the burn-off of initial free rent from recently delivered projects.

Key items included in operating results

Key items included in net income attributable to Alexandria’s common stockholders:
(In millions, except per share amounts)	Amount					Per Share – Diluted				Amount				Per Share – Diluted
	2Q21			2Q20		2Q21		2Q20		1H21		1H20		1H21		1H20
Unrealized gains on non-real estate investments	$	244.0		$	171.7	$	1.67	$	1.38	$	197.8	$	154.5	$	1.39	$	1.25
Realized gains on non-real estate investments	34.8		(1)	—		0.24		—		57.7		—		0.41		—
Gain on sales of real estate	—			—		—		—		2.8		—		0.02		—
Impairment of real estate	(4.9)			(13.2)		(0.03)		(0.11)		(10.1)		(22.9)		(0.07)		(0.18)
Impairment of non-real estate investments	—			(4.7)		—		(0.04)		—		(24.5)		—		(0.20)
Loss on early extinguishment of debt	—			—		—		—		(67.3)		—		(0.47)		—
Total	$	273.9		$	153.8	$	1.88	$	1.23	$	180.9	$	107.1	$	1.28	$	0.87

(1)Refer to “Funds from operations and funds from operations per share” of this Earnings Press Release for additional details.

Alexandria at the vanguard of innovation for over 750 tenants and looking to accommodate current needs plus a path for future growth

•In June 2021, we entered into a definitive agreement to expand our Alexandria Center® at Kendall Square campus through our acquisition of a 100% interest in One Rogers Street and One Charles Park for a purchase price of $815.0 million. This acquisition provides a key expansion to our mega campus strategy in our Cambridge submarket, the premier life science real estate market in the world, and consists of the following:

•Upon closing of the acquisition, we expect to redevelop the two existing buildings, along with the services of The Davis Companies, into a Class A life science project aggregating 400,000 RSF of technical office/laboratory space. We will retain our wholly owned interest in the project upon completion of the redevelopments.

•These two buildings are 100% under lease negotiation with several cutting-edge life science companies.

•The redevelopment project is targeting initial occupancy in 2023.

•Parking garage with approximately 650 spaces.

•We expect to pursue additional entitlement opportunities for future development of additional office/laboratory space at this site.

•We expect to complete this acquisition in December 2021.

•During 2Q21, we completed acquisitions in our key life science cluster submarkets aggregating 5.5 million SF (includes Sequence Drive described in the next bullet); 4.7 million RSF of value-creation opportunities; and 0.9 million RSF of operating space, for an aggregate purchase price of $1.1 billion.

Alexandria at the vanguard of innovation for over 750 tenants and looking to accommodate current needs plus a path for future growth (continued)

•In June 2021, we acquired five operating buildings at 6260, 6290, 6310, 6340, and 6350 Sequence Drive aggregating 487,023 RSF, located in our Sorrento Mesa submarket, for a purchase price of $298.5 million, with opportunity to increase the campus by approximately 400,000 SF through ground-up development.

•The five operating buildings are currently 100% occupied with a weighted-average remaining lease term of 2.7 years. We expect to develop or redevelop these spaces upon expiration of the existing in-place leases.

•The aggregate 887,000 RSF from this acquisition provides a significant future development opportunity to expand our existing Sequence District by Alexandria campus into a flagship mega campus aggregating 1.9 million SF.

Key strategic transactions that generated capital for investment into our highly leased value-creation pipeline and acquisitions with development and redevelopment opportunities

•In April 2021, we sold a 70% partial interest in our 213 East Grand Avenue property located in our South San Francisco submarket for a sales price of $301.0 million, or $1,429 per RSF, representing capitalization rates of 4.5% and 4.0% (cash basis).

•In July 2021, we sold a 70% partial interest in our 400 Dexter Avenue North property located in our Lake Union submarket for a sales price of $254.8 million, or $1,255 per RSF, representing capitalization rates of 4.1% and 4.2% (cash basis).

Balance sheet management

Key metrics as of June 30, 2021

•$36.3 billion of total market capitalization.

•$27.4 billion of total equity capitalization.

•No debt maturities prior to 2024.

•12.5 years weighted-average remaining term of debt as of June 30, 2021.

•Investment-grade credit ratings ranked in the top 10% among all publicly traded U.S. REITs as of June 30, 2021.

	2Q21		Goal
	Quarter	Trailing	4Q21
	Annualized	12 Months	Annualized
Net debt and preferred stock to Adjusted EBITDA	5.8x	6.2x	Less than or equal to 5.2x
Fixed-charge coverage ratio	4.9x	4.6x	Greater than or equal to 5.0x	Value-creation pipeline of new Class A development and redevelopment projects as a percentage of gross investments in real estate	2Q21
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Current and key near-term projects and key pending acquisition 84% leased/negotiating	10%
Income-producing/potential cash flows/covered land play(1)	6%
Land	2%

(1)Includes projects that have existing buildings that are generating or can generate operating cash flows. Also includes development rights associated with existing operating campuses.

Key capital events

•In June 2021, we entered into forward equity sales agreements aggregating $1.5 billion to sell 8.1 million shares of our common stock (including the exercise of underwriters’ option) at a public offering price of $184.00 per share, before underwriting discounts and commissions.

•In 2Q21, we settled a portion of these forward equity sales agreements by issuing 4.9 million shares and received net proceeds of $870.3 million.

•We expect to issue 3.1 million shares in 2H21 to settle our remaining outstanding forward equity sales agreements and receive net proceeds of approximately $547.8 million.

•We also expect to issue 1.5 million shares in 2H21 to settle our remaining outstanding January 2021 forward equity sales agreements and receive net proceeds of approximately $230.5 million.

•During 2Q21, there was no sale activity under our ATM common stock offering program. As of July 26, 2021, the remaining aggregate amount available under our current program for future sales of common stock is $500.0 million.

Investments

•As of June 30, 2021, our investments aggregated $2.0 billion, including an adjusted cost basis of $1.0 billion, unrealized gains of $1.0 billion, and $48.0 million of investments accounted for under the equity method of accounting.

•Investment income of $304.3 million for 2Q21 included $60.2 million in realized gains and $244.0 million in unrealized gains.

Subsequent events

•In July 2021, we completed acquisitions for an aggregate purchase price of $387.9 million, comprising 496,070 RSF of operating properties with future development and redevelopment opportunities and 335,825 RSF of operating properties strategically located across multiple markets.

Industry and ESG leadership: catalyzing and leading the way for positive change to benefit human health and society

Industry leadership

•We were ranked in the top 10 of the world’s largest and most impactful real estate firms on the Forbes 2021 Global 2000 list determined based on sales, profits, assets, and market value.

•In June 2021, we released our 2020 Environmental, Social & Governance Report, which showcases our longstanding ESG commitment and leadership. Key highlights in the report include the company’s critical efforts to tackle climate change by pioneering low-carbon and climate-resilient design solutions (refer to page iii for spotlight on 325 Binney Street), mitigating climate-related risk in our asset base, and investing in and providing essential infrastructure for sustainable agrifoodtech companies; continuing strong progress toward our 2025 environmental impact goals, including further reducing carbon emissions; and catalyzing the health, wellness, safety, and productivity of our employees and tenants, local communities, and the world at large through the built environment and our social responsibility initiatives.

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Acquisitions
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June 30, 2021
(Dollars in thousands)
Property	Submarket/Market	Date of<br>Purchase		Number of Properties		Operating<br>Occupancy		Square Footage								Purchase Price
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			Acquisitions With Development/Redevelopment Opportunities(1)
			Future Development		Active Development/Redevelopment		Operating With Future Development/ Redevelopment		Operating(2)	Operating	Total
Completed in 1Q21				25		94%		374,426	849,411	431,066		1,353,247	80,032	3,088,182				$	1,873,750
Completed in 2Q21:
550 Arsenal Street	Cambridge/Inner Suburbs/Greater Boston	4/21/21		1		98%		775,000	—	260,867		—	—	775,000	(3)				130,000
One Investors Way	Route 128/Greater Boston	4/6/21		1		100%		350,000	—	—		240,000	—	590,000					105,000
1501-1599 Industrial Road	Greater Stanford/San Francisco Bay Area	6/22/21		6		88%		—	—	103,063		—	—	103,063					112,000
2475 Hanover Street	Greater Stanford/San Francisco Bay Area	4/28/21		1		100%		—	—	83,980		—	—	83,980					105,000
6260, 6290, 6310, 6340, and 6350 Sequence Drive	Sorrento Mesa/San Diego	6/10/21		5		100%		887,000	—	487,023		—	—	887,000	(3)				298,476
9601, 9605, 9609, 9613, and 9615 Medical Center Drive	Rockville/Maryland	5/12/21		5		100%		258,000	94,256	—		595,381	—	947,637					80,382
Other	Various	Various		5		77%		1,863,280	37,267	205,983		49,839	—	2,156,369					247,597
				24		96%		4,133,280	131,523	1,140,916		885,220	—	5,543,049					1,078,455
Completed in July 2021:
Other	Various	Various		13		91%		—	—	496,070		335,825	—	831,895					387,941
Pending acquisitions:
Charles Park	Cambridge/Greater Boston	December 2021		2		N/A		TBD(5)	400,000	—		—	—	400,000					815,000
Mercer Mega Block	Lake Union/Seattle	2H21(6)		—		N/A		800,000	—	—		—	—	800,000					143,500
				2				800,000	400,000	—		—	—	1,200,000					958,500
				64				5,307,706	1,380,934	2,068,052		2,574,292	80,032	10,663,126					4,298,646
Other future acquisitions																	661,354
2021 acquisitions																		$	4,960,000
2021 guidance range												4,460,000 – 5,460,000

All values are in US Dollars.

(1)We expect to provide total estimated costs and related yields for development and redevelopment projects in the future, subsequent to the commencement of construction. Refer to “New Class A development and redevelopment properties: current projects” in our Supplemental Information for additional details on active development and redevelopment projects.

(2)Represents the operating component of our value-creation acquisitions that is not expected to undergo development or redevelopment.

(3)Represents total square footage upon completion of development or redevelopment of a new Class A property. Square footage presented includes RSF of buildings currently in operations with future development or redevelopment opportunities. We intend to demolish and develop or redevelop the existing properties upon expiration of the existing in-place leases. Refer to “Definitions and reconciliations” of this Supplemental Information for additional details on value-creation square feet currently included in rental properties.

(4)Upon acquisition of this property, we entered into a 12-year lease with Moderna, Inc.

(5)We expect to pursue additional entitlement opportunities for future development of additional office/laboratory space.

(6)We continue to diligently work through various long-lead-time due diligence items. We are working toward completion of all due diligence items as soon as possible.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	4
Dispositions and Sales of Partial Interest
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June 30, 2021
(Dollars in thousands)
							Capitalization Rate<br><br>(Cash Basis)(1)				Sales Price per RSF		Consideration in Excess of Book Value(2)
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
Property	Submarket/Market	Date of Sale	Interest Sold	RSF	Capitalization Rate(1)				Sales Price
Completed through July 26, 2021:
213 East Grand Avenue	South San Francisco/<br><br>San Francisco Bay Area	4/22/21	70%	300,930	4.5	%	4.0	%			$	1,429	$	103,679
400 Dexter Avenue North	Lake Union/Seattle	7/23/21	70%	290,111	4.1	%	4.2	%		254,814	$	1,255	$	95,467
Land	Other/San Diego	3/12/21	100%	185,000	N/A		N/A			22,900	N/A		(3)

Pending dispositions or sales of partial interest:
Pending(4)	Various	TBD	TBD							285,000 – 385,000	TBD		TBD
2021 guidance range										1,670,000 – 2,170,000

All values are in US Dollars.

(1)Capitalization rates are calculated based upon net operating income and net operating income (cash basis) annualized for the quarter preceding the date on which the property is sold.

(2)We retained control over the newly formed real estate joint venture and therefore continued to consolidate this property. We accounted for the difference between the consideration received and the book value of the interest sold as an equity transaction, with no gain or loss recognized in earnings.

(3)During the three months ended March 31, 2021, we recognized $2.8 million of gains on sales of real estate related to the completion of two real estate dispositions.

(4)Represents transactions in various stages of completion ranging from receipt of offers to signed purchase and sale agreements.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	5
Guidance
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June 30, 2021
(Dollars in millions, except per share amounts)

On June 14, 2021, we issued a current report on Form 8-K providing updates to key 2021 guidance items in connection with our public offering of common stock. The following updated guidance is based on our current view of existing market conditions and assumptions for the year ending December 31, 2021. Our updated guidance does not reflect any significant changes from June 14, 2021, except as noted in the summary of key changes in guidance tables below. Also, refer to our discussion of “forward-looking statements” on page 7 of this Earnings Press Release for additional details.

	2021 Guidance			2021 Guidance
Summary of Key Changes in Guidance	As of 7/26/21	As of 6/14/21	Summary of Key Changes in Guidance	As of 7/26/21	As of 6/14/21
EPS, FFO per share, and FFO per share, as adjusted	See updates below		Fixed-charge coverage ratio – 4Q21 annualized	Greater than or <br>equal to 5.0x	Greater than or <br>equal to 4.8x
Same property net operating income increase	2.0% to 4.0%	1.7% to 3.7%
Same property net operating income increase (cash basis)	4.7% to 6.7%	4.3% to 6.3%
Projected 2021 Earnings per Share and Funds From Operations per Share Attributable to Alexandria’s Common Stockholders – Diluted
---	---	---
	As of 7/26/21	As of 6/14/21
Earnings per share(1)	3.46 to 3.54	1.60 to 1.70
Depreciation and amortization of real estate assets
Gain on sales of real estate
Impairment of real estate – rental properties
Allocation to unvested restricted stock awards
Funds from operations per share(2)	8.95 to 9.03	7.09 to 7.19
Unrealized (gains) losses on non-real estate investments
Realized gains on non-real estate investments(3)
Impairment of real estate
Loss on early extinguishment of debt
Allocation to unvested restricted stock awards
Other
Funds from operations per share, as adjusted(2)	7.71 to 7.79	7.70 to 7.80
Midpoint	7.75	7.75

All values are in US Dollars.

Key Assumptions	Low		High
Occupancy percentage in North America as of December 31, 2021	94.3%		94.9%
Lease renewals and re-leasing of space:
Rental rate increases	31.0%		34.0%
Rental rate increases (cash basis)	18.0%		21.0%
Same property performance:
Net operating income increase	2.0%		4.0%
Net operating income increase (cash basis)	4.7%		6.7%
Straight-line rent revenue	$	119	$	129
General and administrative expenses	$	146	$	151
Capitalization of interest	$	172	$	182
Interest expense	$	128	$	138
Key Credit Metrics	2021 Guidance
---	---
Net debt and preferred stock to Adjusted EBITDA – 4Q21 annualized	Less than or equal to 5.2x
Fixed-charge coverage ratio – 4Q21 annualized	Greater than or equal to 5.0x		Key Sources and Uses of Capital	Range				Midpoint		Certain<br>Completed Items
---	---	---	---	---	---	---	---	---	---
Sources of capital:
Net cash provided by operating activities after dividends	$	210	$	250	$	230
Incremental debt	1,215		875			1,045
2020 debt capital proceeds held in cash	150		250			200
Real estate dispositions and partial interest sales (refer to page 5)	1,670		2,170			1,920	$	579
Common equity	2,975		3,975			3,475	$	3,048	(4)
Total sources of capital	$	6,220	$	7,520	$	6,870
Uses of capital:
Construction (refer to page 43)	$	1,760	$	2,060	$	1,910
Acquisitions (refer to page 4)	4,460		5,460			4,960	$	3,340
Total uses of capital	$	6,220	$	7,520	$	6,870
Incremental debt (included above):
Issuance of unsecured senior notes payable	$	1,750	$	1,750	$	1,750	$	1,750
Principal repayments of unsecured senior notes payable	(650)		(650)			(650)	$	(650)
Unsecured senior line of credit, commercial paper, and other	115		(225)			(55)
Incremental debt	$	1,215	$	875	$	1,045

(1)Excludes unrealized gains or losses after June 30, 2021, that are required to be recognized in earnings and are excluded from funds from operations per share, as adjusted.

(2)Refer to “Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders” in “Definitions and reconciliations” of our Supplemental Information for additional details.

(3)Refer to “Funds from operations and funds from operations per share” of this Earnings Press Release for additional details.

(4)Refer to “Key capital events” on page 3 of this Earnings Press Release for additional details on our June 2021 public offering of common stock. During the six months ended June 30, 2021, we issued 13.8 million shares of common stock and received net proceeds of $2.3 billion. We expect to issue 4.6 million shares in 2H21 to settle our remaining outstanding forward equity sales agreements and receive net proceeds of approximately $778.4 million.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	6
Earnings Call Information and About the Company
---
June 30, 2021

We will host a conference call on Tuesday, July 27, 2021, at 3:00 p.m. Eastern Time (“ET”)/noon Pacific Time (“PT”), which is open to the general public, to discuss our financial and operating results for the second quarter ended June 30, 2021. To participate in this conference call, dial (833) 366-1125 or (412) 902-6738 shortly before 3:00 p.m. ET/noon PT and ask the operator to join the call for Alexandria Real Estate Equities, Inc. The audio webcast can be accessed at www.are.com in the “For Investors” section. A replay of the call will be available for a limited time from 5:00 p.m. ET/2:00 p.m. PT on Tuesday, July 27, 2021. The replay number is (877) 344-7529 or (412) 317-0088, and the access code is 10156073.

Additionally, a copy of this Earnings Press Release and Supplemental Information for the second quarter ended June 30, 2021, is available in the “For Investors” section of our website at www.are.com or by following this link: http://www.are.com/fs/2021q2.pdf.

For any questions, please contact Joel S. Marcus, executive chairman and founder; Stephen A. Richardson, co-chief executive officer; Peter M. Moglia, co-chief executive officer and co-chief investment officer; Dean A. Shigenaga, president and chief financial officer; or Paula Schwartz, managing director of Rx Communications Group, at (917) 322-2216; or Sara M. Kabakoff, vice president – communications, at (626) 578-0777.

About the Company

Alexandria Real Estate Equities, Inc. (NYSE:ARE), an S&P 500® urban office real estate investment trust (“REIT”), is the first, longest-tenured, and pioneering owner, operator, and developer uniquely focused on collaborative life science, agtech, and technology campuses in AAA innovation cluster locations, with a total market capitalization of $36.3 billion as of June 30, 2021, and an asset base in North America of 58.1 million square feet (“SF”). The asset base in North America includes 36.7 million RSF of operating properties and 3.4 million RSF of Class A properties undergoing construction, 7.7 million RSF of near-term and intermediate-term development and redevelopment projects, and 10.3 million SF of future development projects. Founded in 1994, Alexandria pioneered this niche and has since established a significant market presence in key locations, including Greater Boston, the San Francisco Bay Area, New York City, San Diego, Seattle, Maryland, and Research Triangle. Alexandria has a longstanding and proven track record of developing Class A properties clustered in urban life science, agtech, and technology campuses that provide our innovative tenants with highly dynamic and collaborative environments that enhance their ability to successfully recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to transformative life science, agtech, and technology companies through our venture capital platform. We believe our unique business model and diligent underwriting ensure a high-quality and diverse tenant base that results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. For additional information on Alexandria, please visit www.are.com.

***********

This document includes “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Such forward-looking statements include, without limitation, statements regarding our 2021 earnings per share attributable to Alexandria’s common stockholders – diluted, 2021 funds from operations per share attributable to Alexandria’s common stockholders – diluted, net operating income, and our projected sources and uses of capital. You can identify the forward-looking statements by their use of forward-looking words, such as “forecast,” “guidance,” “goals,” “projects,” “estimates,” “anticipates,” “believes,” “expects,” “intends,” “may,” “plans,” “seeks,” “should,” “targets,” or “will,” or the negative of those words or similar words. These forward-looking statements are based on our current expectations, beliefs, projections, future plans and strategies, anticipated events or trends, and similar expressions concerning matters that are not historical facts, as well as a number of assumptions concerning future events. There can be no assurance that actual results will not be materially higher or lower than these expectations. These statements are subject to risks, uncertainties, assumptions, and other important factors that could cause actual results to differ materially from the results discussed in the forward-looking statements. Factors that might cause such a difference include, without limitation, our failure to obtain capital (debt, construction financing, and/or equity) or refinance debt maturities, increased interest rates and operating costs, adverse economic or real estate developments in our markets (including the impact of the ongoing COVID-19 pandemic), our failure to successfully place into service and lease any properties undergoing development or redevelopment and our existing space held for future development or redevelopment (including new properties acquired for that purpose), our failure to successfully operate or lease acquired properties, decreased rental rates, increased vacancy rates or failure to renew or replace expiring leases, defaults on or non-renewal of leases by tenants, adverse general and local economic conditions, an unfavorable capital market environment, decreased leasing activity or lease renewals, failure to obtain LEED and other healthy building certifications and efficiencies, and other risks and uncertainties detailed in our filings with the Securities and Exchange Commission (“SEC”). Accordingly, you are cautioned not to place undue reliance on such forward-looking statements. All forward-looking statements are made as of the date of this Earnings Press Release and Supplemental Information, and unless otherwise stated, we assume no obligation to update this information and expressly disclaim any obligation to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise. For more discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated in our forward-looking statements, and risks to our business in general, please refer to our SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q.

For additional discussion of the risks and other potential impacts posed by the outbreak of the COVID-19 pandemic and uncertainties we, our tenants, and the global and national economies face as a result, see the sections entitled “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” in our annual report on Form 10-K filed with the SEC on February 1, 2021.

Alexandria®, Lighthouse Design® logo, Building the Future of Life-Changing Innovation™, That’s What’s in Our DNA®, Labspace®, Alexandria Center®, Alexandria Technology Square®, Alexandria Technology Center®, Alexandria Innovation Center®, and Alexandria Summit® are copyrights and trademarks of Alexandria Real Estate Equities, Inc. All other company names, trademarks, and logos referenced herein are the property of their respective owners.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	7
Consolidated Statements of Operations
---
June 30, 2021
(Dollars in thousands, except per share amounts)			Three Months Ended										Six Months Ended
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
	6/30/21		3/31/21		12/31/20		9/30/20		6/30/20		6/30/21		6/30/20
Revenues:
Income from rentals	$	508,371	$	478,695	$	461,335	$	543,412	$	435,856	$	987,066	$	873,461
Other income	1,248		1,154		2,385		1,630		1,100		2,402		3,414
Total revenues	509,619		479,849		463,720		545,042		436,956		989,468		876,875
Expenses:
Rental operations	143,955		137,888		136,767		140,443		123,911		281,843		253,014
General and administrative	37,880		33,996		32,690		36,913		31,775		71,876		63,738
Interest	35,158		36,467		37,538		43,318		45,014		71,625		90,753
Depreciation and amortization	190,052		180,913		177,750		176,831		168,027		370,965		343,523
Impairment of real estate	4,926		5,129		25,177		7,680		13,218		10,055		15,221
Loss on early extinguishment of debt	—		67,253		7,898		52,770		—		67,253		—
Total expenses	411,971		461,646		417,820		457,955		381,945		873,617		766,249
Equity in earnings of unconsolidated real estate joint ventures	2,609		3,537		3,593		3,778		3,893		6,146		777
Investment income	304,263		1,014		255,137		3,348		184,657		305,277		162,836
Gain on sales of real estate	—		2,779		152,503		1,586		—		2,779		—
Net income	404,520		25,533		457,133		95,799		243,561		430,053		274,239
Net income attributable to noncontrolling interests	(19,436)		(17,412)		(15,649)		(14,743)		(13,907)		(36,848)		(25,820)
Net income attributable to Alexandria Real Estate Equities, Inc.’s stockholders	385,084		8,121		441,484		81,056		229,654		393,205		248,419
Net income attributable to unvested restricted stock awards	(4,521)		(2,014)		(5,561)		(1,730)		(3,054)		(4,663)		(3,574)
Net income attributable to Alexandria Real Estate Equities, Inc.’s common stockholders	$	380,563	$	6,107	$	435,923	$	79,326	$	226,600	$	388,542	$	244,845
Net income per share attributable to Alexandria Real Estate Equities, Inc.’s common stockholders:
Basic	$	2.61	$	0.04	$	3.26	$	0.64	$	1.82	$	2.74	$	1.99
Diluted	$	2.61	$	0.04	$	3.26	$	0.63	$	1.82	$	2.74	$	1.99
Weighted-average shares of common stock outstanding:
Basic	145,825		137,319		133,688		124,901		124,333		141,596		122,883
Diluted	146,058		137,688		133,827		125,828		124,448		141,896		123,117
Dividends declared per share of common stock	$	1.12	$	1.09	$	1.09	$	1.06	$	1.06	$	2.21	$	2.09
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	8
---	---
Consolidated Balance Sheets
---
June 30, 2021
(In thousands)			6/30/21		3/31/21		12/31/20		9/30/20		6/30/20
---	---	---	---	---	---	---	---	---	---	---
Assets
Investments in real estate	$	21,692,385	$	20,253,418	$	18,092,372	$	17,600,648	$	16,281,125
Investments in unconsolidated real estate joint ventures	323,622		325,928		332,349		330,792		326,858
Cash and cash equivalents	323,876		492,184		568,532		446,255		206,860
Restricted cash	33,697		42,219		29,173		38,788		34,680
Tenant receivables	6,710		7,556		7,333		7,641		7,208
Deferred rent	781,600		751,967		722,751		719,552		688,749
Deferred leasing costs	321,005		294,328		272,673		266,440		274,483
Investments	1,999,283		1,641,811		1,611,114		1,330,945		1,318,465
Other assets	1,536,672		1,424,935		1,191,581		1,169,610		930,680
Total assets	$	27,018,850	$	25,234,346	$	22,827,878	$	21,910,671	$	20,069,108
Liabilities, Noncontrolling Interests, and Equity
Secured notes payable	$	227,984	$	229,406	$	230,925	$	342,363	$	344,784
Unsecured senior notes payable	8,313,025		8,311,512		7,232,370		7,230,819		6,738,486
Unsecured senior line of credit and commercial paper	299,990		—		99,991		249,989		440,000
Accounts payable, accrued expenses, and other liabilities	1,825,387		1,750,687		1,669,832		1,609,340		1,343,181
Dividends payable	170,647		160,779		150,982		143,040		133,681
Total liabilities	10,837,033		10,452,384		9,384,100		9,575,551		9,000,132
Commitments and contingencies
Redeemable noncontrolling interests	11,567		11,454		11,342		11,232		12,122
Alexandria Real Estate Equities, Inc.’s stockholders’ equity:
Common stock	1,507		1,457		1,367		1,333		1,246
Additional paid-in capital	14,194,023		12,994,748		11,730,970		10,711,119		9,443,274
Accumulated other comprehensive loss	(4,508)		(5,799)		(6,625)		(10,638)		(13,080)
Alexandria Real Estate Equities, Inc.’s stockholders’ equity	14,191,022		12,990,406		11,725,712		10,701,814		9,431,440
Noncontrolling interests	1,979,228		1,780,102		1,706,724		1,622,074		1,625,414
Total equity	16,170,250		14,770,508		13,432,436		12,323,888		11,056,854
Total liabilities, noncontrolling interests, and equity	$	27,018,850	$	25,234,346	$	22,827,878	$	21,910,671	$	20,069,108
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	9
---	---
Funds From Operations and Funds From Operations per Share
---
June 30, 2021
(In thousands)

The following table presents a reconciliation of net income (loss) attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in accordance with U.S. generally accepted accounting principles (“GAAP”), including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations attributable to Alexandria’s common stockholders – diluted, and funds from operations attributable to Alexandria’s common stockholders – diluted, as adjusted, for the periods below:

	Three Months Ended											Six Months Ended
	6/30/21			3/31/21		12/31/20		9/30/20		6/30/20		6/30/21		6/30/20
Net income attributable to Alexandria’s common stockholders	$	380,563		$	6,107	$	435,923	$	79,326	$	226,600	$	388,542	$	244,845
Depreciation and amortization of real estate assets	186,498			177,720		173,392		173,622		165,040		364,218		337,668
Noncontrolling share of depreciation and amortization from consolidated real estate JVs	(16,301)			(15,443)		(15,032)		(15,256)		(15,775)		(31,744)		(31,645)
Our share of depreciation and amortization from unconsolidated real estate JVs	4,135			3,076		2,976		2,936		2,858		7,211		5,501
Gain on sales of real estate	—			(2,779)		(152,503)		(1,586)		—		(2,779)		—
Impairment of real estate – rental properties	1,754			5,129		25,177		7,680		—		6,883		7,644
Allocation to unvested restricted stock awards	(2,191)			(201)		(420)		(1,261)		(2,228)		(4,427)		(4,531)
Funds from operations attributable to Alexandria’s common stockholders – diluted(1)	554,458			173,609		469,513		245,461		376,495		727,904		559,482
Unrealized (gains) losses on non-real estate investments	(244,031)			46,251		(233,538)		14,013		(171,652)		(197,780)		(154,508)
Realized gains on non-real estate investments	(34,773)		(2)	(22,919)		—		—		—		(57,692)		—
Impairment of non-real estate investments	—			—		—		—		4,702		—		24,482
Impairment of real estate	3,172			—		—		—		13,218		3,172		15,221
Loss on early extinguishment of debt	—			67,253		7,898		52,770		—		67,253		—
Termination fee	—			—		—		(86,179)		—		—		—
Acceleration of stock compensation expense due to executive officer resignation	—			—		—		4,499		—		—		—
Allocation to unvested restricted stock awards	3,428			(1,208)		2,774		179		2,251		2,382		1,711
Funds from operations attributable to Alexandria’s common stockholders – diluted, as adjusted	$	282,254		$	262,986	$	246,647	$	230,743	$	225,014	$	545,239	$	446,388

(1)Calculated in accordance with standards established by the Nareit Board of Governors. Refer to “Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders” in the “Definitions and reconciliations” of our Supplemental Information for additional details.

(2)Represents realized gains related to the sales of our investments in two publicly traded biotechnology companies.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	10
Funds From Operations and Funds From Operations per Share (continued)
---
June 30, 2021
(In thousands, except per share amounts)

The following table presents a reconciliation of net income (loss) per share attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in accordance with GAAP, including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations per share attributable to Alexandria’s common stockholders – diluted, and funds from operations per share attributable to Alexandria’s common stockholders – diluted, as adjusted, for the periods below. Per share amounts may not add due to rounding.

	Three Months Ended										Six Months Ended
	6/30/21		3/31/21		12/31/20		9/30/20		6/30/20		6/30/21		6/30/20
Net income per share attributable to Alexandria’s common stockholders – diluted	$	2.61	$	0.04	$	3.26	$	0.63	$	1.82	$	2.74	$	1.99
Depreciation and amortization of real estate assets	1.19		1.20		1.21		1.28		1.22		2.39		2.53
Gain on sales of real estate	—		(0.02)		(1.14)		(0.01)		—		(0.02)		—
Impairment of real estate – rental properties	0.01		0.04		0.19		0.06		—		0.05		0.06
Allocation to unvested restricted stock awards	(0.01)		—		(0.01)		(0.01)		(0.01)		(0.03)		(0.04)
Funds from operations per share attributable to Alexandria’s common stockholders – diluted	3.80		1.26		3.51		1.95		3.03		5.13		4.54
Unrealized (gains) losses on non-real estate investments	(1.67)		0.34		(1.75)		0.11		(1.38)		(1.39)		(1.25)
Realized gains on non-real estate investments	(0.24)		(0.17)		—		—		—		(0.41)		—
Impairment of non-real estate investments	—		—		—		—		0.04		—		0.20
Impairment of real estate	0.02		—		—		—		0.11		0.02		0.12
Loss on early extinguishment of debt	—		0.49		0.06		0.42		—		0.47		—
Termination fee	—		—		—		(0.69)		—		—		—
Acceleration of stock compensation expense due to executive officer resignation	—		—		—		0.04		—		—		—
Allocation to unvested restricted stock awards	0.02		(0.01)		0.02		—		0.01		0.02		0.02
Funds from operations per share attributable to Alexandria’s common stockholders – diluted, as adjusted	$	1.93	$	1.91	$	1.84	$	1.83	$	1.81	$	3.84	$	3.63
Weighted-average shares of common stock outstanding – diluted(1)	146,058		137,688		133,827		125,828		124,448		141,896		123,117

(1)Refer to “Weighted-average shares of common stock outstanding – diluted” in the “Definitions and reconciliations” of our Supplemental Information for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	11

SUPPLEMENTAL

INFORMATION

Company Profile
June 30, 2021

Alexandria Real Estate Equities, Inc. (NYSE:ARE), an S&P 500® urban office REIT, is the first, longest-tenured, and pioneering owner, operator, and developer uniquely focused on collaborative life science, agtech, and technology campuses in AAA innovation cluster locations, with a total market capitalization of $36.3 billion as of June 30, 2021, and an asset base in North America of 58.1 million SF. The asset base in North America includes 36.7 million RSF of operating properties and 3.4 million RSF of Class A properties undergoing construction, 7.7 million RSF of near-term and intermediate-term development and redevelopment projects, and 10.3 million SF of future development projects. Founded in 1994, Alexandria pioneered this niche and has since established a significant market presence in key locations, including Greater Boston, the San Francisco Bay Area, New York City, San Diego, Seattle, Maryland, and Research Triangle. Alexandria has a longstanding and proven track record of developing Class A properties clustered in urban life science, agtech, and technology campuses that provide our innovative tenants with highly dynamic and collaborative environments that enhance their ability to successfully recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to transformative life science, agtech, and technology companies through our venture capital platform. We believe our unique business model and diligent underwriting ensure a high-quality and diverse tenant base that results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. For additional information on Alexandria, please visit www.are.com.

Tenant base

Alexandria is known for our high-quality and diverse tenant base, with 53% of our annual rental revenue generated from tenants that are investment-grade rated or publicly traded large cap companies. The quality, diversity, breadth, and depth of our significant relationships with our tenants provide Alexandria with high-quality and stable cash flows. Alexandria’s underwriting team and long-term industry relationships positively distinguish us from all other publicly traded REITs and real estate companies.

Executive and senior management team

Alexandria’s executive and senior management team has unique experience and expertise in creating, owning, and operating highly dynamic and collaborative campuses in key urban life science, agtech, and technology cluster locations that inspire innovation. From the development of high-quality, sustainable real estate, to the ongoing cultivation of collaborative environments with unique amenities and events, the Alexandria team has a first-in-class reputation of excellence in our niche. Alexandria’s highly experienced management team also includes regional market directors with leading reputations and longstanding relationships within the life science, agtech, and technology communities in their respective innovation clusters. We believe that our expertise, experience, reputation, and key relationships in the real estate, life science, agtech, and technology sectors provide Alexandria significant competitive advantages in attracting new business opportunities.

Alexandria’s executive and senior management team consists of 52 individuals, averaging 25 years of real estate experience, including 11 years with Alexandria. Our executive management team alone averages 17 years of experience with Alexandria.

EXECUTIVE MANAGEMENT TEAM
Joel S. Marcus	Stephen A. Richardson
Executive Chairman & Founder	Co-Chief Executive Officer
Dean A. Shigenaga	Peter M. Moglia
President & Chief Financial Officer	Co-Chief Executive Officer & <br>Co-Chief Investment Officer
Daniel J. Ryan	Lawrence J. Diamond
Co-Chief Investment Officer & Regional Market Director – San Diego	Co-Chief Operating Officer & Regional Market Director – Maryland
Vincent R. Ciruzzi	John H. Cunningham
Chief Development Officer	Executive Vice President – Regional Market Director – New York City
Hunter L. Kass	Jackie B. Clem
Executive Vice President – Regional Market Director – Greater Boston	General Counsel & Secretary
Joseph Hakman	Terezia C. Nemeth
Co-Chief Operating Officer & <br>Chief Strategic Transactions Officer	Executive Vice President – Regional Market Director – San Francisco <br>Bay Area
Marc E. Binda	Andres R. Gavinet
Executive Vice President – <br>Finance & Treasurer	Chief Accounting Officer
Gary D. Dean
Executive Vice President – <br>Real Estate Legal Affairs
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	13
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Investor Information
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June 30, 2021		Corporate Headquarters	New York Stock Exchange Trading Symbol	Information Requests
---	---	---	---
26 North Euclid Avenue	Common stock: ARE	Phone:	(626) 578-0777
Pasadena, California 91101		Email:	corporateinformation@are.com
		Website:	www.are.com		Equity Research Coverage
---		Alexandria is currently covered by the following research analysts. This list may be incomplete and is subject to change as firms initiate or discontinue coverage of our company. Please note that any opinions, estimates, or forecasts regarding our historical or predicted performance made by these analysts are theirs alone and do not represent opinions, estimates, or forecasts of Alexandria or our management. Alexandria does not by our reference or distribution of the information below imply our endorsement of or concurrence with any opinions, estimates, or forecasts of these analysts. Interested persons may obtain copies of analysts’ reports on their own as we do not distribute these reports. Several of these firms may, from time to time, own our stock and/or hold other long or short positions in our stock and may provide compensated services to us.
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Bank of America Merrill Lynch	Citigroup Global Markets Inc.	JMP Securities	RBC Capital Markets
---	---	---	---
Jamie Feldman / Elvis Rodriguez	Michael Bilerman / Emmanuel Korchman	Aaron Hecht	Michael Carroll / Jason Idoine
(646) 855-5808 / (646) 855-1589	(212) 816-1383 / (212) 816-1382	(415) 835-3963	(440) 715-2649 / (440) 715-2651
Berenberg Capital Markets	Evercore ISI	J.P. Morgan Securities LLC	Robert W. Baird & Co. Incorporated
Connor Siversky / Nate Crossett	Sheila McGrath / Wendy Ma	Anthony Paolone / Ray Zhong	David Rodgers / Nicholas Thillman
(646) 949-9037 / (646) 949-9030	(212) 497-0882 / (212) 497-0870	(212) 622-6682 / (212) 622-5411	(216) 737-7341 / (414) 298-5053
BTIG, LLC	Green Street	Mizuho Securities USA LLC	SMBC Nikko Securities America, Inc.
Tom Catherwood / James Sullivan	Daniel Ismail / Dylan Burzinski	Haendel St. Juste / Lydia Jiang	Richard Anderson / Jay Kornreich
(212) 738-6140 / (212) 738-6139	(949) 640-8780 / (949) 640-8780	(212) 205-7860 / (212) 209-9379	(646) 521-2351 / (646) 424-3202
CFRA
Kenneth Leon
(646) 517-2552
Fixed Income Coverage		Rating Agencies
Barclays Capital Inc.	Stifel Financial Corp.	Moody’s Investors Service	S&P Global Ratings
Srinjoy Banerjee / Devon Zhou	Thierry Perrein	(212) 553-0376	Fernanda Hernandez / Michael Souers
(212) 526-3521 / (212) 526-6961	(646) 376-5303		(212) 438-1347 / (212) 438-2508
J.P. Morgan Securities LLC
Mark Streeter / Ian Snyder
(212) 834-5086 / (212) 834-3798					Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	14
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Financial and Asset Base Highlights
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June 30, 2021
(Dollars in thousands, except per share amounts)
	Three Months Ended (unless stated otherwise)
---	---	---	---	---	---
	6/30/21	3/31/21	12/31/20	9/30/20	6/30/20
Selected financial data from consolidated financial statements and related information
Rental revenues
Tenant recoveries
General and administrative expenses
General and administrative expenses as a percentage of net operating income –<br><br>trailing 12 months	9.8%	9.8%	9.8%	9.9%	10.3%
Operating margin	72%	71%	71%	74%	72%
Adjusted EBITDA margin	69%	69%	69%	67%	69%
Adjusted EBITDA – quarter annualized
Adjusted EBITDA – trailing 12 months
Net debt at end of period
Net debt and preferred stock to Adjusted EBITDA – quarter annualized	5.8x	5.8x	5.3x	5.8x	5.8x
Net debt and preferred stock to Adjusted EBITDA – trailing 12 months	6.2x	6.1x	5.5x	6.0x	6.2x
Fixed-charge coverage ratio – quarter annualized	4.9x	4.7x	4.6x	4.3x	4.2x
Fixed-charge coverage ratio – trailing 12 months	4.6x	4.4x	4.4x	4.3x	4.2x
Unencumbered net operating income as a percentage of total net operating income	97%	97%	97%	96%	95%
Closing stock price at end of period
Common shares outstanding (in thousands) at end of period	150,708	145,656	136,690	133,312	124,559
Total equity capitalization at end of period
Total market capitalization at end of period
Dividend per share – quarter/annualized	1.12/4.48	1.09/4.36	1.09/4.36	1.06/4.24	1.06/4.24
Dividend payout ratio for the quarter	60%	60%	60%	61%	59%
Dividend yield – annualized	2.5%	2.7%	2.4%	2.7%	2.6%
Amounts related to operating leases:
Operating lease liabilities
Rent expense
Capitalized interest
Weighted-average interest rate for capitalization of interest during the period	3.47%	3.44%	3.66%	3.64%	4.03%

All values are in US Dollars.

| Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021 | 15 | | --- | --- || Financial and Asset Base Highlights (continued) | | --- | | June 30, 2021 | | (Dollars in thousands, except annual rental revenue per occupied RSF amounts) || | Three Months Ended (unless stated otherwise) | | | | | | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | 6/30/21 | | | 3/31/21 | | 12/31/20 | | 9/30/20 | | 6/30/20 | | | Amounts included in funds from operations and non-revenue-enhancing capital expenditures | | | | | | | | | | | | | Straight-line rent revenue | $ | 27,903 | | $ | 27,382 | $ | 23,890 | $ | 28,822 | $ | 23,367 | | Amortization of acquired below-market leases | $ | 13,267 | | $ | 12,112 | $ | 13,514 | $ | 13,979 | $ | 13,787 | | Straight-line rent expense on ground leases | $ | 248 | | $ | 290 | $ | 348 | $ | 229 | $ | 167 | | Stock compensation expense | $ | 12,242 | | $ | 12,446 | $ | 11,394 | $ | 12,994 | $ | 9,185 | | Amortization of loan fees | $ | 2,859 | | $ | 2,817 | $ | 2,905 | $ | 2,605 | $ | 2,737 | | Amortization of debt premiums | $ | 465 | | $ | 576 | $ | 869 | $ | 910 | $ | 888 | | Non-revenue-enhancing capital expenditures: | | | | | | | | | | | | | Building improvements | $ | 3,669 | | $ | 3,760 | $ | 3,466 | $ | 3,358 | $ | 3,107 | | Tenant improvements and leasing commissions | $ | 47,439 | (1) | $ | 16,035 | $ | 31,235 | $ | 34,036 | $ | 11,500 | | Operating statistics and related information (at end of period) | | | | | | | | | | | | | Number of properties – North America | 381 | | | 360 | | 338 | | 326 | | 304 | | | RSF – North America (including development and redevelopment projects under construction) | 40,076,883 | | | 37,916,882 | | 35,163,572 | | 34,071,653 | | 31,141,758 | | | Total square feet – North America | 58,108,390 | | | 52,591,039 | | 49,712,701 | | 47,389,023 | | 43,023,989 | | | Annual rental revenue per occupied RSF – North America | $ | 48.65 | | $ | 49.58 | $ | 49.08 | $ | 49.55 | $ | 51.30 | | Occupancy of operating properties – North America | 94.3% | | (2) | 94.5% | | 94.6% | | 94.9% | | 94.8% | | | Occupancy of operating and redevelopment properties – North America | 90.1% | | | 89.2% | | 90.0% | | 91.3% | | 92.3% | | | Weighted-average remaining lease term (in years) | 7.5 | | | 7.6 | | 7.6 | | 7.7 | | 7.8 | | | Total leasing activity – RSF | 1,933,838 | | | 1,677,659 | | 1,369,599 | | 1,208,382 | | 1,077,510 | | | Lease renewals and re-leasing of space – change in average new rental rates over expiring rates: | | | | | | | | | | | | | Rental rate increases | 42.4% | | | 36.2% | | 29.8% | | 39.9% | | 37.2% | | | Rental rate increases (cash basis) | 25.4% | | | 17.4% | | 10.7% | | 30.9% | | 15.0% | | | RSF (included in total leasing activity above) | 1,472,713 | | | 521,825 | | 699,916 | | 605,765 | | 699,130 | | | Same property – percentage change over comparable quarter from prior year: | | | | | | | | | | | | | Net operating income increase | 3.7% | | | 4.4% | | 2.7% | | 2.9% | | 0.6% | | | Net operating income increase (cash basis) | 7.8% | | | 6.1% | | 5.0% | | 4.9% | | 2.5% | |

(1)During 2Q21, historic demand for our high-quality office/laboratory space translated into 1.9 million RSF of leasing activity and 42.4% of rental rate growth, representing the highest leasing activity in a single quarter, and second highest rental rate growth, in Company history. Tenant improvements and leasing commissions per RSF granted for 2Q21 was consistent with 1Q21. Refer to “Leasing activity” in this Supplemental Information for additional details.

(2)Refer to “Occupancy” in this Supplemental Information for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	16
High-Quality, Diverse, and Innovative Tenants
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June 30, 2021

Long-Duration Cash Flows From High-Quality, Diverse, and

Innovative Tenants

Investment-Grade or<br>Publicly Traded Large Cap Tenants		Tenant Mix
	53%
of ARE’s Annual Rental Revenue(1)
Long-Duration Lease Terms
	7.5 Years
Weighted-Average Remaining Term(2)
		Percentage of ARE’s Annual Rental Revenue(1)

(1)Represents annual rental revenue in effect as of June 30, 2021.

(2)Based on aggregate annual rental revenue in effect as of June 30, 2021. Refer to “Annual rental revenue” in the “Definitions and reconciliations” of this Supplemental Information for additional details about our methodology on annual rental revenue from unconsolidated real estate joint ventures.

(3)Represents annual rental revenue currently generated from office space that is targeted for a future change in use. The weighted-average remaining term of these leases is 2.9 years.

(4)Represents annual rental revenue from publicly traded technology tenants with an average daily market capitalization greater than $200 billion for the twelve months ended June 30, 2021.

(5)Our other tenants, aggregating 5.0% of our annual rental revenue, comprise 3.9% of annual rental revenue from technology, professional services, finance, telecommunications, and construction/real estate companies and only 1.1% from retail-related tenants.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	17
Class A Properties in AAA Locations
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June 30, 2021

High-Quality Cash Flows From High-Quality Tenants and

Class A Properties in AAA Locations

Industry-Leading<br>Tenant Roster	AAA Locations
85%
of ARE’s Top 20 Tenants’
Annual Rental Revenue(1)
Is From Investment-Grade
or Publicly Traded Large Cap Tenants
	Percentage of ARE’s Annual Rental Revenue(1)

(1)Represents annual rental revenue in effect as of June 30, 2021.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	18
Occupancy
---
June 30, 2021		Solid Historical Occupancy(1)	Occupancy Across Key Locations(2)
---	---
96%
Over 10 Years

(1)Represents average occupancy of operating properties in North America as of each December 31 for the last 10 years and as of June 30, 2021.

(2)As of June 30, 2021.

(3)Excludes 1.4 million RSF, or 3.8%, of vacancy at recently acquired properties in our North America markets (noted below), representing lease-up opportunities that are expected to provide incremental annual rental revenues in excess of $55 million. Approximately 35% of the vacant 1.4 million RSF is currently under leased/negotiating, with occupancy expected primarily over the next two quarters. Excluding these acquired vacancies, occupancy of operating properties in North America was 98.1% as of June 30, 2021. The following table provides vacancy detail for our recent acquisitions:

									Incremental Projected Annual Rental Revenue<br>Upon Full Lease-Up
		As of June 30, 2021					Percentage of Vacancy Leased/Negotiating
		Vacant	Occupancy Impact
Property	Market/Submarket	RSF	Region		Consolidated
Alexandria Center® for Life Science – Durham	Research Triangle/Research Triangle	204,034	6.5	%	0.6	%	70	%	>$55 million
601, 611, and 651 Gateway Boulevard	San Francisco Bay Area/South San Francisco	310,863	3.9	%	0.9		20
Alexandria Center® for Life Science – Fenway	Greater Boston/Fenway	96,992	1.0	%	0.3		39
SD Tech by Alexandria	San Diego/Sorrento Mesa	82,566	1.2	%	0.2		9
Other acquisitions	Various	693,501	N/A		1.8		34
		1,387,956			3.8	%	35	%		Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	19
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Key Operating Metrics
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June 30, 2021		Historical Same Property<br>Net Operating Income		Favorable Lease Structure(1)
---	---	---	---	---
		Strategic Lease Structure by Owner and Operator of Collaborative <br>Life Science, Agtech, and Technology Campuses
	Increasing cash flows
	Percentage of leases containing<br><br>annual rent escalations			95%
	Stable cash flows
	Percentage of triple<br><br>net leases			94%
	Lower capex burden
	Percentage of leases providing for the<br><br>recapture of capital expenditures			94%
Historical Rental Rates: <br>Renewed/Re-Leased Space		Margins(2)
	Operating		Adjusted EBITDA
	72%		69%

(1)Percentages calculated based on RSF as of June 30, 2021.

(2)Represents percentages for the three months ended June 30, 2021.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	20
Same Property Performance
---
June 30, 2021
(Dollars in thousands)			June 30, 2021			June 30, 2021
---	---	---	---	---	---
Same Property Financial Data	Three Months Ended	Six Months Ended	Same Property Statistical Data	Three Months Ended	Six Months Ended
Percentage change over comparable period from prior year:			Number of same properties	260	250
Net operating income increase	3.7%	4.4%	Rentable square feet	25,523,121	23,730,512
Net operating income increase (cash basis)	7.8%	7.4%	Occupancy – current-period average	95.0%	96.5%
Operating margin	73%	73%	Occupancy – same-period prior-year average	95.1%	96.2%
	Three Months Ended June 30,							Six Months Ended June 30,
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
	2021		2020		Change	% Change		2021		2020		Change	% Change
Income from rentals:
Same properties	$	321,450	$	311,627		3.2	%	$	607,884	$	588,729		3.3	%
Non-same properties	75,354		29,928		45,426	151.8		159,153		90,768		68,385	75.3
Rental revenues	396,804		341,555		55,249	16.2		767,037		679,497		87,540	12.9
Same properties	97,669		88,682		8,987	10.1		192,670		179,546		13,124	7.3
Non-same properties	13,898		5,619		8,279	147.3		27,359		14,418		12,941	89.8
Tenant recoveries	111,567		94,301		17,266	18.3		220,029		193,964		26,065	13.4
Income from rentals	508,371		435,856		72,515	16.6		987,066		873,461		113,605	13.0
Same properties	104		14		90	642.9		205		140		65	46.4
Non-same properties	1,144		1,086		58	5.3		2,197		3,274		(1,077)	(32.9)
Other income	1,248		1,100		148	13.5		2,402		3,414		(1,012)	(29.6)
Same properties	419,223		400,323		18,900	4.7		800,759		768,415		32,344	4.2
Non-same properties	90,396		36,633		53,763	146.8		188,709		108,460		80,249	74.0
Total revenues	509,619		436,956		72,663	16.6		989,468		876,875		112,593	12.8
Same properties	113,673		105,693		7,980	7.6		216,827		208,894		7,933	3.8
Non-same properties	30,282		18,218		12,064	66.2		65,016		44,120		20,896	47.4
Rental operations	143,955		123,911		20,044	16.2		281,843		253,014		28,829	11.4
Same properties	305,550		294,630		10,920	3.7		583,932		559,521		24,411	4.4
Non-same properties	60,114		18,415		41,699	226.4		123,693		64,340		59,353	92.2
Net operating income	$	365,664	$	313,045		16.8	%	$	707,625	$	623,861		13.4	%
Net operating income – same properties	$	305,550	$	294,630		3.7	%	$	583,932	$	559,521		4.4	%
Straight-line rent revenue	(15,394)		(23,829)		8,435	(35.4)		(32,272)		(42,645)		10,373	(24.3)
Amortization of acquired below-market leases	(4,527)		(5,940)		1,413	(23.8)		(6,717)		(9,368)		2,651	(28.3)
Net operating income – same properties (cash basis)	$	285,629	$	264,861		7.8	%	$	544,943	$	507,508		7.4	%

All values are in US Dollars.

Refer to “Same property comparisons” in the “Definitions and reconciliations” of this Supplemental Information for a reconciliation of same properties to total properties. “Definitions and reconciliations” also contains definitions of “Tenant recoveries” and “Net operating income” and their respective reconciliations from the most directly comparable financial measures presented in accordance with GAAP.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	21
Leasing Activity
---
June 30, 2021
(Dollars per RSF)
		Three Months Ended			Six Months Ended			Year Ended
---	---	---	---	---	---	---	---	---	---
		June 30, 2021			June 30, 2021			December 31, 2020
	Including <br>Straight-Line Rent		Cash Basis			Cash Basis
Leasing activity:
Renewed/re-leased space(1)
Rental rate changes		42.4%		25.4%	40.7%		23.3%	37.6%	18.3%
New rates		58.70		56.16	58.41		55.82	49.51	$46.53
Expiring rates		41.22		44.77	41.51		45.29	35.99	$39.32
RSF		1,472,713			1,994,538			2,556,833
Tenant improvements/leasing commissions		32.06			31.82			35.08
Weighted-average lease term		5.8 years			6.1 years			6.0 years
Developed/redeveloped/previously vacant space leased(2)
New rates		57.61		53.52	51.56		47.91	56.67	$53.61
RSF		461,125			1,616,959			1,802,013
Weighted-average lease term		7.5 years			9.8 years			9.0 years
Leasing activity summary (totals):
New rates		58.44		55.53	55.34		52.28	52.47	$49.46
RSF		1,933,838			3,611,497			4,358,846
Weighted-average lease term		6.2 years			7.7 years			7.3 years
Lease expirations(1)
Expiring rates		40.06		43.13	40.25		43.35	36.03	$39.01
RSF		1,712,307			2,459,582			3,560,188

All values are in US Dollars.

Leasing activity includes 100% of results for each property in which we have an investment in North America.

(1)Excludes month-to-month leases aggregating 88,305 RSF and 96,383 RSF as of June 30, 2021, and December 31, 2020, respectively.

(2)Refer to “New Class A development and redevelopment projects: summary of pipeline” of this Supplemental Information for additional information on total project costs.

(3)Represents the highest leasing activity in a single quarter in Company history.

(4)During the six months ended June 30, 2021, we granted tenant concessions/free rent averaging 2.6 months with respect to the 3,611,497 RSF leased. Approximately 47% of the leases executed during the six months ended June 30, 2021, did not include concessions for free rent.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	22
Contractual Lease Expirations
---
June 30, 2021		Year			RSF		Percentage of<br>Occupied RSF			Annual Rental Revenue (per RSF)(1)			Percentage of Total<br>Annual Rental Revenue
---	---	---	---	---	---	---	---	---	---	---	---	---	---
	2021	(2)		913,052		2.7	%		$	46.74		2.6	%
	2022			2,503,192		7.3	%		$	45.14		6.8	%
	2023			3,472,768		10.1	%		$	40.58		8.5	%
	2024			2,912,682		8.5	%		$	43.28		7.6	%
	2025			2,778,313		8.1	%		$	51.54		8.7	%
	2026			2,077,113		6.0	%		$	48.24		6.1	%
	2027			2,109,753		6.1	%		$	50.48		6.4	%
	2028			2,951,361		8.6	%		$	50.79		9.1	%
	2029			2,132,286		6.2	%		$	53.42		6.9	%
	2030			2,299,958		6.7	%		$	53.53		7.5	%
Thereafter				10,225,279		29.7	%		$	48.19		29.8	%
Market		2021 Contractual Lease Expirations (in RSF)														Annual Rental Revenue<br><br>(per RSF)(1)			2022 Contractual Lease Expirations (in RSF)													Annual Rental Revenue<br><br>(per RSF)(1)
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
	Leased			Negotiating/<br>Anticipating			Targeted for<br><br>Development/<br><br>Redevelopment(3)			Remaining<br>Expiring<br>Leases			Total(2)					Leased		Negotiating/<br>Anticipating		Targeted for<br><br>Development/<br><br>Redevelopment(3)			Remaining<br><br>Expiring Leases(4)				Total
Greater Boston		57,247			62,312			202,428			35,120			357,107		$	46.37		118,555		149,849		—			275,190		(5)		543,594		$	58.71
San Francisco Bay Area		122,534			4,570			—			73,301			200,405		57.99			—		33,498		490,127			233,583				757,208		52.08
New York City		30,408			—			—			4,973			35,381		N/A			—		14,891		—			3,264				18,155		N/A
San Diego		46,586			—			84,359			35,085			166,030		37.40			103,730		—		250,028			211,117				564,875		36.31
Seattle		24,990			6,053			—			33,341			64,384		18.62			—		—		51,255			151,092				202,347		34.39
Maryland		7,268			—			—			76			7,344		35.23			7,638		18,090		—			50,865				76,593		29.11
Research Triangle		23,435			—			—			43,911			67,346		30.78			—		30,039		—			207,409				237,448		22.48
Canada		—			—			—			—			—		—			—		—		—			28,623				28,623		22.57
Non-cluster/other markets		—			—			—			15,055			15,055		86.16			—		—		—			74,349				74,349		44.25
Total		312,468			72,935			286,787			240,862			913,052		$	46.74		229,923		246,367		791,410			1,235,492				2,503,192		$	45.14
Percentage of expiring leases		34	%		8	%		31	%		27	%		100	%				9	%	10	%	32	%		49	%			100	%

(1)Represents amounts in effect as of June 30, 2021.

(2)Excludes month-to-month leases aggregating 88,305 RSF as of June 30, 2021.

(3)Represents RSF targeted for development or redevelopment upon expiration of existing in-place leases, primarily related to recently acquired properties. Refer to “Investments in real estate” in the “Definitions and reconciliations” of this Supplemental Information for additional details on value-creation square feet currently included in rental properties.

(4)The largest remaining contractual lease expiration includes one lease for 62,490 RSF in our Research Triangle submarket.

(5)57% of the remaining expiring leases in Greater Boston are located in our Cambridge/Inner Suburbs submarket.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	23
Top 20 Tenants
---
June 30, 2021
(Dollars in thousands, except average market cap amounts)

85% of Top 20 Annual Rental Revenue From Investment-Grade

or Publicly Traded Large Cap Tenants(1)

	Tenant								Percentage of Aggregate Annual Rental Revenue(1)		Investment-Grade <br>Credit Ratings		Average Market Cap(1)<br><br>(in billions)
				Moody’s		S&P
1	Bristol-Myers Squibb Company	7.2			916,234		$	53,100	3.3	%	A2	A+	$	140.0
2	Takeda Pharmaceutical Company Ltd.	8.1			606,249		39,342		2.4		Baa2	BBB+	$	55.8
3	Moderna, Inc.	11.2			855,458		39,341		2.4		—	—	$	48.9
4	Facebook, Inc.	10.5			903,786		38,595		2.4		—	—	$	797.7
5	Eli Lilly and Company	7.5			580,693		37,047		2.3		A2	A+	$	167.4
6	Illumina, Inc.	9.1			891,495		36,118		2.2		Baa3	BBB	$	55.3
7	Sanofi	8.1			494,693		35,040		2.1		A1	AA	$	126.5
8	Novartis AG	7.1			423,914		30,216		1.9		A1	AA-	$	217.7
9	Uber Technologies, Inc.	61.4	(2)		1,009,188		27,379		1.7		—	—	$	84.7
10	Roche	2.8	(3)		546,893		26,040		1.6		Aa3	AA	$	299.6
11	bluebird bio, Inc.	5.9			312,805		23,142		1.4		—	—	$	3.0
12	Maxar Technologies	4.2	(4)		478,000		21,803		1.3		—	—	$	2.1
13	Massachusetts Institute of Technology	7.5			257,626		21,145		1.3		Aaa	AAA	$	—
14	United States Government	13.8			918,516		20,236		1.2		Aaa	AA+	$	—
15	The Children’s Hospital Corporation	17.3			269,816		20,066		1.2		Aa2	AA	$	—
16	Jazz Pharmaceuticals, Inc.	9.2			198,041		20,003		1.2		—	—	$	8.6
17	New York University	10.2			204,691		19,531		1.2		Aa2	AA-	$	—
18	Merck & Co., Inc.	12.9			311,015		19,392		1.2		A1	AA-	$	200.2
19	Pfizer Inc.	3.7			416,979		17,762		1.1		A2	A+	$	207.3
20	FibroGen, Inc.	7.4			234,249		16,896		1.0		—	—	$	3.4
	Total/weighted-average	11.1	(2)		10,830,341		$	562,194	34.4	%

(1)Based on aggregate annual rental revenue in effect as of June 30, 2021. Refer to “Annual rental revenue” and “Investment-grade or publicly traded large cap tenants” in the “Definitions and reconciliations” of this Supplemental Information for additional details about our methodology on annual rental revenue from unconsolidated real estate joint ventures and average daily market capitalization.

(2)Includes (i) ground leases for land at 1455 and 1515 Third Street (two buildings aggregating 422,980 RSF) and (ii) leases at 1655 and 1725 Third Street (two buildings aggregating 586,208 RSF) owned by our unconsolidated real estate joint venture in which we have an ownership interest of 10%. Annual rental revenue is presented using 100% of the annual rental revenue of our consolidated properties and our share of annual rental revenue for our unconsolidated real estate joint ventures. Refer to footnote 1 for additional details. Excluding the ground lease, the weighted-average remaining lease term for our top 20 tenants was 8.5 years as of June 30, 2021.

(3)Includes 197,787 RSF expiring in 2022 at our recently acquired property at 651 Gateway Boulevard in our South San Francisco submarket. Upon expiration of the lease, 651 Gateway Boulevard will be redeveloped into a Class A office/laboratory building. Excluding this 197,787 RSF, the weighted-average remaining term of space leased to Roche is 3.4 years.

(4)Represents remaining lease term at two properties with future redevelopment and development opportunities. The leases with this tenant were in place when we acquired the properties in 4Q19.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	24
Summary of Properties and Occupancy
---
June 30, 2021
(Dollars in thousands, except per RSF amounts)

Summary of properties

Market		RSF										Number of Properties		Annual Rental Revenue
	Operating		Development		Redevelopment		Total		% of Total				Total			% of Total		Per RSF
Greater Boston		9,893,984		510,116		490,545		10,894,645		27	%	77		$	579,594		36	%	$	61.32
San Francisco Bay Area		8,046,553		368,149		92,147		8,506,849		21		66		408,038			25		61.46
New York City		1,160,472		—		120,027		1,280,499		3		5		83,961			5		72.80
San Diego		7,102,797		341,891		117,212		7,561,900		19		88		263,165			16		39.49
Seattle		2,628,577		—		213,976		2,842,553		7		40		108,354			7		42.26
Maryland		3,593,787		84,264		344,226		4,022,277		10		50		95,592			6		26.88
Research Triangle		3,137,115		410,000		325,936		3,873,051		10		35		71,093			4		24.42
Canada		268,551		—		—		268,551		1		3		5,164			—		24.98
Non-cluster/other markets		600,709		—		—		600,709		1		13		11,174			1		40.41
Properties held for sale		225,849		—		—		225,849		1		4		6,168			—		N/A
North America		36,658,394		1,714,420		1,704,069		40,076,883		100	%	381		$	1,632,303		100	%	$	48.65
				3,418,489

Summary of occupancy

	Operating Properties							Operating and Redevelopment Properties
Market	6/30/21			3/31/21		6/30/20		6/30/21		3/31/21		6/30/20
Greater Boston	95.5	%	(1)	96.2	%	98.2	%	91.0	%	91.5	%	95.6	%
San Francisco Bay Area	94.0		(1)(2)	95.4		94.7		92.9		94.3		90.6
New York City	99.4			99.4		97.1		90.1		89.8		86.2
San Diego	93.8		(1)	93.3		91.8		92.3		90.3		90.8
Seattle	97.6			96.8		95.1		90.2		89.6		95.1
Maryland	98.9			97.9		93.9		90.3		90.4		93.2
Research Triangle	92.8		(1)	90.8		96.8		84.1		73.7		96.8
Subtotal	95.2			95.3		95.1		90.9		89.9		92.6
Canada	77.0			81.6		90.0		77.0		81.6		90.0
Non-cluster/other markets	46.0			52.6		70.8		46.0		52.6		70.8
North America	94.3	%	(1)	94.5	%	94.8	%	90.1	%	89.2	%	92.3	%

(1)Refer to “Occupancy” of this Supplemental Information for additional details on vacancy at recently acquired properties.

(2)Decline from 1Q21 is due to the expiration of two leases aggregating 131,069 RSF in our South San Francisco submarket, of which 96% has been re-leased and is expected to be occupied by the new tenants over the next few quarters.

Refer to “Definitions and reconciliations” of this Supplemental Information for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	25
Property Listing
---
June 30, 2021
(Dollars in thousands)		Market / Submarket / Address					RSF							Number of Properties	Annual Rental Revenue		Occupancy Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						Operating			Operating and Redevelopment
		Operating		Development			Redevelopment			Total
Greater Boston
	Cambridge/Inner Suburbs
			Alexandria Center® at Kendall Square		2,365,487			—		—	2,365,487	10	$	170,833	98.9	%	98.9	%
			50, 60, 75/125(1), 100, and 225(1) Binney Street, 161 and 215 First Street, 150 Second Street, 300 Third Street, and 11 Hurley Street
			Alexandria Technology Square®		1,181,635			—		—	1,181,635	7	101,895		97.9		97.9
			100, 200, 300, 400, 500, 600, and 700 Technology Square
			The Arsenal on the Charles		475,743			—		360,545	836,288	11	18,235		89.3		50.8
			311, 321, and 343 Arsenal Street, 300 and 400 North Beacon Street,<br> 1, 2, and 3 Kingsbury Avenue, and 100, 200, and 400 Talcott Avenue
			Alexandria Center® at One Kendall Square		814,779			—		—	814,779	10	69,534		96.3		96.3
			One Kendall Square – Buildings 100, 200, 300, 400, 500, 600/700, 1400, 1800, and 2000 and 399 Binney Street
			480, 500, and 550 Arsenal Street		495,127			—		—	495,127	3	20,631		98.3		98.3
			640 Memorial Drive		225,504			—		—	225,504	1	13,860		100.0		100.0
			780 and 790 Memorial Drive		99,658			—		—	99,658	2	8,358		100.0		100.0
			167 Sidney Street and 99 Erie Street		54,549			—		—	54,549	2	4,025		100.0		100.0
			79/96 13th Street (Charlestown Navy Yard)		25,309			—		—	25,309	1	620		100.0		100.0
			Cambridge/Inner Suburbs		5,737,791			—		360,545	6,098,336	47	407,991		97.5		91.8
	Fenway
			Alexandria Center® for Life Science – Fenway		973,145			510,116		—	1,483,261	2	56,725		90.0		90.0
			401 Park Drive and 201 Brookline Avenue(1)
	Seaport Innovation District
			380 and 420 E Street		195,506			—		—	195,506	2	3,911		100.0		100.0
			5 Necco Street		87,163			—		—	87,163	1	4,672		86.6		86.6
			Seaport Innovation District		282,669			—		—	282,669	3	8,583		95.9		95.9
	Route 128
			Reservoir Woods		515,273			—		—	515,273	3	21,808		100.0		100.0
			40, 50, and 60 Sylvan Road
			275 Grove Street		509,702			—		—	509,702	1	18,418		73.5		73.5
			One Upland Road, 100 Tech Drive, and One Investors Way		683,513			—		—	683,513	3	25,202		100.0		100.0
			Alexandria Park at 128		343,882			—		—	343,882	8	12,544		100.0		100.0
			3 and 6/8 Preston Court, 29, 35, and 44 Hartwell Avenue, 35 and 45/47 Wiggins Avenue, and 60 Westview Street
			225, 266, and 275 Second Avenue		317,617			—		—	317,617	3	13,515		84.8		84.8
			19 Presidential Way		144,892			—		—	144,892	1	5,045		94.7		94.7
			840 Winter Street		30,009			—		130,000	160,009	1	1,315		100.0		18.8
			100 Beaver Street		82,330			—		—	82,330	1	4,886		100.0		100.0
			285 Bear Hill Road		26,270			—		—	26,270	1	1,167		100.0		100.0
			Route 128		2,653,488			—		130,000	2,783,488	22	$	103,900	92.8	%	88.5	%
			(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” of this Supplemental Information for additional details.																Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	26
---	---		Property Listing (continued)
---
June 30, 2021
(Dollars in thousands)		Market / Submarket / Address					RSF							Number of Properties	Annual Rental Revenue		Occupancy Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						Operating			Operating and Redevelopment
		Operating		Development			Redevelopment			Total
Greater Boston (continued)
	Route 495
			111 and 130 Forbes Boulevard		155,846			—		—	155,846	2	$	1,746	100.0	%	100.0	%
			20 Walkup Drive		91,045			—		—	91,045	1	649		100.0		100.0
			Route 495		246,891			—		—	246,891	3	2,395		100.0		100.0
			Greater Boston		9,893,984			510,116		490,545	10,894,645	77	579,594		95.5		91.0
San Francisco Bay Area
	Mission Bay
			Alexandria Center® for Science and Technology – Mission Bay		1,990,262			—		—	1,990,262	9	95,196		99.8		99.9
			1455, 1515, 1655(1), and 1725(1) Third Street, 409 and 499 Illinois Street(1), 1500(1) and 1700 Owens Street, and 455 Mission Bay Boulevard South
			Mission Bay		1,990,262			—		—	1,990,262	9	95,196		99.8		99.8
	South San Francisco
			Alexandria Technology Center® – Gateway		1,415,020			—		—	1,415,020	11	57,788		76.4		76.4
			600, 601(1), 611(1), 630, 650, 651(1), 681(1), 685(1), 701(1), 901, and 951<br><br>Gateway Boulevard
			213(1), 249, 259, 269, and 279 East Grand Avenue		919,704			—		—	919,704	5	48,911		100.0		100.0
			Alexandria Center® for Life Science – South San Francisco		334,077			152,148		—	486,225	3	17,670		80.3		80.3
			201 Haskins Way and 400 and 450 East Jamie Court
			500 Forbes Boulevard(1)		155,685			—		—	155,685	1	6,619		100.0		100.0
			7000 Shoreline Court		139,709			—		—	139,709	1	8,643		100.0		100.0
			341 and 343 Oyster Point Boulevard		108,208			—		—	108,208	2	6,443		100.0		100.0
			849/863 Mitten Road/866 Malcolm Road		103,857			—		—	103,857	1	4,564		100.0		100.0
			South San Francisco		3,176,260			152,148		—	3,328,408	24	150,638		87.4		87.4
	Greater Stanford
			Menlo Gateway(1)		772,983			—		—	772,983	3	29,486		100.0		100.0
			100 Independence Drive and 125 and 135 Constitution Drive
			Alexandria Center® for Life Science – San Carlos		523,240			216,001		—	739,241	9	32,242		97.6		97.6
			825, 835, 960, and 1501-1599 Industrial Road
			3825 and 3875 Fabian Way		478,000			—		—	478,000	2	21,802		100.0		100.0
			Alexandria Stanford Life Science District		289,685			—		92,147	381,832	4	23,888		100.0		75.9
			3160, 3165, 3170, and 3181 Porter Drive
			Alexandria PARC		197,498			—		—	197,498	4	9,297		78.1		78.1
			2100, 2200, 2300, and 2400 Geng Road
			3330, 3412, 3450, and 3460 Hillview Avenue		183,267			—		—	183,267	4	15,180		100.0		100.0
			2475 and 2625/2627/2631 Hanover Street		116,054			—		—	116,054	2	9,531		94.1		94.1
			2425 Garcia Avenue/2400/2450 Bayshore Parkway		99,208			—		—	99,208	1	$	4,257	100.0	%	100.0	%
			(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” of this Supplemental Information for additional details.																Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	27
---	---		Property Listing (continued)
---
June 30, 2021
(Dollars in thousands)		Market / Submarket / Address					RSF							Number of Properties	Annual Rental Revenue		Occupancy Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						Operating			Operating and Redevelopment
		Operating		Development			Redevelopment			Total
San Francisco Bay Area (continued)
	Greater Stanford (continued)
			Shoreway Science Center		82,462			—		—	82,462	2	$	5,422	100.0	%	100.0	%
			75 and 125 Shoreway Road
			1450 Page Mill Road		77,634			—		—	77,634	1	8,009		100.0		100.0
			3350 West Bayshore Road		60,000			—		—	60,000	1	3,090		74.3		74.3
			Greater Stanford		2,880,031			216,001		92,147	3,188,179	33	162,204		97.3		94.3
			San Francisco Bay Area		8,046,553			368,149		92,147	8,506,849	66	408,038		94.0		92.9
New York City
	New York City
			Alexandria Center® for Life Science – New York City		740,972			—		—	740,972	3	66,741		99.0		99.0
			430 and 450 East 29th Street
			219 East 42nd Street		349,947			—		—	349,947	1	14,006		100.0		100.0
			Alexandria Center® for Life Science – Long Island City		69,553			—		120,027	189,580	1	3,214		100.0		36.7
			30-02 48th Avenue
			New York City		1,160,472			—		120,027	1,280,499	5	83,961		99.4		90.1
San Diego
	Torrey Pines
			ARE Spectrum		336,461			146,456		—	482,917	4	18,076		100.0		100.0
			3115 and 3215 Merryfield Row and 3013 and 3033 Science Park Road
			ARE Sunrise		321,464			—		—	321,464	4	7,642		76.8		76.8
			10931/10933 and 10975 North Torrey Pines Road, 3010 Science Park Road, and 10975, 10995, and 10996 Torreyana Road
			ARE Torrey Ridge		294,326			—		—	294,326	3	12,678		84.6		84.6
			10578, 10618, and 10628 Science Center Drive
			ARE Nautilus		220,651			—		—	220,651	4	10,924		100.0		100.0
			3530 and 3550 John Hopkins Court and 3535 and 3565 General Atomics Court
			11119, 11255, and 11355 North Torrey Pines Road		211,641			—		—	211,641	3	8,738		100.0		100.0
			3545 Cray Court		118,225			—		—	118,225	1	3,636		46.1		46.1
			Torrey Pines		1,502,768			146,456		—	1,649,224	19	$	61,694	87.8	%	87.8	%	Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	28
---	---		Property Listing (continued)
---
June 30, 2021
(Dollars in thousands)		Market / Submarket / Address					RSF							Number of Properties	Annual Rental Revenue		Occupancy Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						Operating			Operating and Redevelopment
		Operating		Development			Redevelopment			Total
San Diego (continued)
	University Town Center
			Alexandria Point(1)		1,435,916			—		—	1,435,916	8	$	62,685	100.0	%	100.0	%
			9880(2), 10210, 10260, 10290, and 10300 Campus Point Drive and 4161, 4224, and 4242 Campus Point Court
			5200 Illumina Way(1)		792,687			—		—	792,687	6	29,977		100.0		100.0
			University District		448,954			—		—	448,954	6	18,870		100.0		100.0
			9393 and 9625(1) Towne Centre Drive, 4755, 4757, and 4767 Nexus Center Drive, and 4796 Executive Drive
			University Town Center		2,677,557			—		—	2,677,557	20	111,532		100.0		100.0
	Sorrento Mesa
			SD Tech by Alexandria(1)		779,989			195,435		79,945	1,055,369	14	23,925		86.1		78.1
			9605, 9645, 9675, 9685, 9725, 9735, 9808, 9855, and 9868 Scranton Road, 5505 Morehouse Drive(2), and 10055, 10065, 10121(2), and 10151(2) Barnes Canyon Road
			Sequence District by Alexandria		805,223			—		—	805,223	7	25,817		92.5		92.5
			6260, 6290, 6310, 6340, 6350, 6420, and 6450 Sequence Drive
			Summers Ridge Science Park		316,531			—		—	316,531	4	11,077		100.0		100.0
			9965, 9975, 9985, and 9995 Summers Ridge Road
			ARE Portola		101,857			—		—	101,857	3	3,603		100.0		100.0
			6175, 6225, and 6275 Nancy Ridge Drive
			9444 Waples Street		88,380			—		—	88,380	1	1,636		61.2		61.2
			5810/5820 Nancy Ridge Drive		82,272			—		—	82,272	1	1,031		41.4		41.4
			7330 Carroll Road		66,244			—		—	66,244	1	2,431		100.0		100.0
			9877 Waples Street		63,774			—		—	63,774	1	2,374		100.0		100.0
			5871 Oberlin Drive		33,842			—		—	33,842	1	1,710		100.0		100.0
			Sorrento Mesa		2,338,112			195,435		79,945	2,613,492	33	73,604		89.3		86.3
	Sorrento Valley
			3911, 3931, 3985, 4025, 4031, 4045, and 4075 Sorrento Valley Boulevard		191,406			—		—	191,406	7	6,483		100.0		100.0
			11025, 11035, 11045, 11055, 11065, and 11075 Roselle Street		121,655			—		—	121,655	6	3,328		97.1		97.1
			Sorrento Valley		313,061			—		—	313,061	13	9,811		98.9		98.9
	Other				271,299			—		37,267	308,566	3	6,524		100.0		87.9
			San Diego		7,102,797			341,891		117,212	7,561,900	88	$	263,165	93.8	%	92.3	%
			(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” of this Supplemental Information for additional details.<br><br>(2)We own 100% of this property.																Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	29
---	---		Property Listing (continued)
---
June 30, 2021
(Dollars in thousands)		Market / Submarket / Address					RSF							Number of Properties	Annual Rental Revenue		Occupancy Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						Operating			Operating and Redevelopment
		Operating		Development			Redevelopment			Total
Seattle
	Lake Union
			The Eastlake Life Science Campus by Alexandria		937,290			—		—	937,290	8	$	56,782	100.0	%	100.0	%
			1165, 1201(1), 1208(1), 1551, and 1616 Eastlake Avenue East, 188 and 199(1) East Blaine Street, and 1600 Fairview Avenue East
			400 Dexter Avenue North		290,111			—		—	290,111	1	14,441		100.0		100.0
			2301 5th Avenue		197,135			—		—	197,135	1	9,308		99.0		99.0
			219 Terry Avenue North		30,705			—		—	30,705	1	1,852		100.0		100.0
			601 Dexter Avenue North		18,680			—		—	18,680	1	425		100.0		100.0
			Lake Union		1,473,921			—		—	1,473,921	12	82,808		99.9		99.9
	SoDo
			830 4th Avenue South		42,380			—		—	42,380	1	1,479		70.5		70.5
	Elliott Bay
			3000/3018 Western Avenue		47,746			—		—	47,746	1	1,839		100.0		100.0
			410 West Harrison Street and 410 Elliott Avenue West		36,724			—		—	36,724	2	912		68.2		68.2
			Elliott Bay		84,470			—		—	84,470	3	2,751		86.2		86.2
	Other				1,027,806			—		213,976	1,241,782	24	21,316		96.3		79.7
			Seattle		2,628,577			—		213,976	2,842,553	40	108,354		97.6		90.2
Maryland
	Rockville
			9601, 9605, 9609, 9613, and 9615 Medical Center Drive		711,072			—		94,256	805,328	6	5,334		99.8		88.2
			9800, 9804, 9900, 9920, and 9950 Medical Center Drive		560,788			84,264		—	645,052	8	24,225		100.0		100.0
			9704, 9708, 9712, and 9714 Medical Center Drive		215,619			—		—	215,619	4	7,937		100.0		100.0
			1330 Piccard Drive		131,511			—		—	131,511	1	4,021		100.0		100.0
			1500 and 1550 East Gude Drive		90,489			—		—	90,489	2	1,411		77.3		77.3
			14920 and 15010 Broschart Road		86,703			—		—	86,703	2	2,283		100.0		100.0
			1405 Research Boulevard		72,170			—		—	72,170	1	2,476		100.0		100.0
			5 Research Place		63,852			—		—	63,852	1	2,743		100.0		100.0
			5 Research Court		51,520			—		—	51,520	1	1,788		100.0		100.0
			9920 Belward Campus Drive		51,181			—		—	51,181	1	1,966		100.0		100.0
			12301 Parklawn Drive		49,185			—		—	49,185	1	1,329		100.0		100.0
			Rockville		2,084,090			84,264		94,256	2,262,610	28	55,513		99.0		94.7
	Gaithersburg
			Alexandria Technology Center® – Gaithersburg I		613,438			—		—	613,438	9	16,729		98.9		98.9
			9, 25, 35, 45, 50, and 55 West Watkins Mill Road and 910, 930, and 940 Clopper Road
			Alexandria Technology Center® – Gaithersburg II		315,085			—		169,420	484,505	7	$	10,342	99.0	%	64.4	%
			700, 704, and 708 Quince Orchard Road and 19, 20, 21, and 22 Firstfield Road
	(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” of this Supplemental Information for additional details.																		Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	30
---	---		Property Listing (continued)
---
June 30, 2021
(Dollars in thousands)		Market / Submarket / Address					RSF							Number of Properties	Annual Rental Revenue		Occupancy Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						Operating			Operating and Redevelopment
		Operating		Development			Redevelopment			Total
Maryland (continued)
	Gaithersburg (Continued)
			20400 Century Boulevard		—			—		80,550	80,550	1	$	—	N/A		—
			401 Professional Drive		63,154			—		—	63,154	1	1,899		100.0	%	100.0	%
			950 Wind River Lane		50,000			—		—	50,000	1	1,004		100.0		100.0
			620 Professional Drive		27,950			—		—	27,950	1	1,207		100.0		100.0
			Gaithersburg		1,069,627			—		249,970	1,319,597	20	31,181		99.1		80.3
	Beltsville
			8000/9000/10000 Virginia Manor Road		191,884			—		—	191,884	1	2,771		96.7		96.7
	Northern Virginia
			14225 Newbrook Drive		248,186			—		—	248,186	1	6,127		100.0		100.0
			Maryland		3,593,787			84,264		344,226	4,022,277	50	95,592		98.9		90.3
Research Triangle
	Research Triangle
			Alexandria Center® for Life Science – Durham		1,912,211			—		325,936	2,238,147	16	34,208		89.3		76.3
			6, 8, 10, 12, 14, 40, 41, 42, and 65 Moore Drive, 21, 25, 27, 29, and 31<br><br>Parmer Way, 2400 Ellis Road, and 14 TW Alexander Drive
			Alexandria Center® for Advanced Technologies		100,000			250,000		—	350,000	3	2,606		96.7		96.7
			6, 8, and 10 Davis Drive
			Alexandria Center® for AgTech		180,400			160,000		—	340,400	2	6,880		95.2		95.2
			5 and 9 Laboratory Drive
			Alexandria Technology Center® – Alston		186,870			—		—	186,870	3	4,216		94.5		94.5
			100, 800, and 801 Capitola Drive
			108/110/112/114 TW Alexander Drive		158,417			—		—	158,417	1	5,393		100.0		100.0
			Alexandria Innovation Center® – Research Triangle		136,455			—		—	136,455	3	4,129		100.0		100.0
			7010, 7020, and 7030 Kit Creek Road
			7 Triangle Drive		96,626			—		—	96,626	1	3,156		100.0		100.0
			2525 East NC Highway 54		82,996			—		—	82,996	1	3,651		100.0		100.0
			407 Davis Drive		81,956			—		—	81,956	1	1,644		100.0		100.0
			601 Keystone Park Drive		77,395			—		—	77,395	1	1,375		100.0		100.0
			6040 George Watts Hill Drive		61,547			—		—	61,547	1	2,148		100.0		100.0
			5 Triangle Drive		32,120			—		—	32,120	1	1,147		100.0		100.0
			6101 Quadrangle Drive		30,122			—		—	30,122	1	540		100.0		100.0
			Research Triangle		3,137,115			410,000		325,936	3,873,051	35	71,093		92.8		84.1
Canada					268,551			—		—	268,551	3	5,164		77.0		77.0
Non-cluster/other markets					600,709			—		—	600,709	13	11,174		46.0		46.0
North America, excluding properties held for sale					36,432,545			1,714,420		1,704,069	39,851,034	377	1,626,135		94.3	%	90.1	%
Properties held for sale					225,849			—		—	225,849	4	6,168		51.1	%	51.1	%
Total – North America					36,658,394			1,714,420		1,704,069	40,076,883	381	$	1,632,303
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	31
---	---
Investments in Real Estate
---
June 30, 2021

Demand for our value-creation development and redevelopment projects of high-quality office/laboratory space, as well as continued operational excellence at our world-class, sophisticated laboratory facilities and strong execution by our team, has translated into record leasing activity.

Under Construction		Projects Expected to Commence Construction in 2021/2022(1)		Incremental<br>Projected Annual Rental Revenues
3.4 Million RSF		3.6 Million RSF		>$545 million
33 Properties	+	19 Properties	=
80% Leased/Negotiating		89% Leased/Negotiating

(1)We also expect other projects to commence construction in 2021.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	32
Investments in Real Estate
---
June 30, 2021
(Dollars in thousands)

As of July 26, 2021, construction activities were in process at all of our active construction projects. Construction workers continue to observe social distancing and follow rules that restrict gatherings of large groups of people in close proximity, as well as adhere to other appropriate measures, which may slow the pace of construction.

			Development and Redevelopment
	Operating		Under Construction		Near<br>Term			Intermediate<br>Term		Future		Subtotal		Total
Investments in real estate
Book value as of June 30, 2021(1)	$	20,575,715	$	1,858,986	$	1,224,340		$	578,541	$	879,729	$	4,541,596	$	25,117,311
Square footage
Operating	36,658,394		—		—			—		—		—		36,658,394
New Class A development and redevelopment properties	—		3,418,489		5,740,386		(2)	3,189,951		13,073,721		25,422,547		25,422,547
Value-creation square feet currently included in rental properties(3)	—		—		(818,052)			(369,173)		(2,785,326)		(3,972,551)		(3,972,551)
Total square footage	36,658,394		3,418,489		4,922,334			2,820,778		10,288,395		21,449,996		58,108,390

(1)Balances exclude our share of the cost basis associated with our properties held by our unconsolidated real estate joint ventures, which is classified as investments in unconsolidated real estate joint ventures in our consolidated balance sheets. Refer to “Investments in real estate” in the “Definitions and reconciliations” of this Supplemental Information for reconciliation detail of investments in real estate.

(2)Includes 3,554,058 RSF, currently 89% leased/negotiating, expected to commence vertical construction or redevelopment during 2021/2022. Refer to “New Class A development and redevelopment properties: current projects” for additional details.

(3)Refer to “Investments in real estate” in the “Definitions and reconciliations” of this Supplemental Information for additional details on value-creation square feet currently included in rental properties.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	33
New Class A Development and Redevelopment Properties: Recent Deliveries
---
June 30, 2021		Alexandria Center® for Life Science –<br><br>South San Francisco(1)	Alexandria Center® for Life Science –<br><br>San Carlos	Alexandria Center® for Life Science –<br><br>Long Island City
---	---	---
San Francisco Bay Area/South San Francisco	San Francisco Bay Area/Greater Stanford	New York City/New York City
171,042 RSF	310,177 RSF	32,892 RSF
100% Leased	100% Leased	100% Leased		9877 Waples Street	1165 Eastlake Avenue East	9804 Medical Center Drive	Alexandria Center® for Life Science – Durham(2)
---	---	---	---
San Diego/Sorrento Mesa	Seattle/Lake Union	Maryland/Rockville	Research Triangle/Research Triangle
63,774 RSF	100,086 RSF	176,832 RSF	326,445 RSF
100% Leased	100% Leased	100% Leased	100% Leased

(1)Image represents 201 Haskins Way in our Alexandria Center® for Life Science – South San Francisco.

(2)Image represents 2400 Ellis Road in our Alexandria Center® for Life Science – Durham campus.

| Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021 | 34 | | --- | --- || New Class A Development and Redevelopment Properties: Recent Deliveries (continued) | | --- | | June 30, 2021 | | (Dollars in thousands) | | Property/Market/Submarket | | | Our Ownership Interest | | RSF Placed in Service | | | | | | | | Occupancy Percentage(1) | | Total Project | | | | Unlevered Yields | | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | Delivery Date | | | 4Q20 | | 1Q21 | | 2Q21 | | Total | | | | Initial Stabilized | | Initial Stabilized (Cash Basis) | | | | | | | | | | | | | | RSF | | | Investment | | | | Development projects | | | | | | | | | | | | | | | | | | | | | | | | | | | Alexandria Center® for Life Science – South San Francisco/San Francisco Bay Area/South San Francisco | | Various | 100% | | — | | — | | 171,042 | | 171,042 | | | 100% | 323,190 | | $ | 370,000 | | 6.4 | % | | 6.2 | % | | | Alexandria Center® for Life Science – San Carlos/<br><br>San Francisco Bay Area/Greater Stanford | | Various | 100% | | 96,463 | | 99,557 | | 114,157 | | 310,177 | | | 100% | 526,178 | | 630,000 | | | 6.4 | | | 6.1 | | | | 1165 Eastlake Avenue East/Seattle/Lake Union | | March 2021 | 100% | | — | | 100,086 | | — | | 100,086 | | | 100% | 100,086 | | 138,000 | | | 6.3 | | (2) | 6.4 | | (2) | | 9804 Medical Center Drive/Maryland/Rockville | | January 2021 | 100% | | — | | 176,832 | | — | | 176,832 | | | 100% | 176,832 | | 89,300 | | | 8.3 | | | 8.0 | | | | Redevelopment projects | | | | | | | | | | | | | | | | | | | | | | | | | | | Alexandria Center® for Life Science – Long Island City/New York City/New York City | | Various | 100% | | 17,716 | | — | | 15,176 | | 32,892 | | | 100% | 189,580 | | 184,300 | | | 5.5 | | | 5.6 | | | | 9877 Waples Street/San Diego/Sorrento Mesa | | December 2020 | 100% | | 63,774 | | — | | — | | 63,774 | | | 100% | 63,744 | | 31,000 | | | 8.8 | | | 8.1 | | | | Other/San Diego | | June 2021 | 100% | | — | | — | | 128,745 | | 128,745 | | | 100% | 128,745 | | 47,000 | | | 8.0 | | (3) | 8.0 | | (3) | | Alexandria Center® for Life Science – Durham/Research Triangle/Research Triangle | | June 2021 | 100% | | — | | — | | 326,445 | | 326,445 | | | 100% | 652,381 | | 245,000 | | | 7.5 | | | 6.7 | | | | Total | | | | | 177,953 | | 376,475 | | 755,565 | | 1,309,993 | | | | | | $ | 1,734,600 | | 6.6 | % | | 6.4 | % | |

Refer to “New Class A development and redevelopment properties: current projects” of this Supplemental Information for details on the RSF in service and under construction, if applicable.

(1)Relates to total operating RSF placed in service as of the most recent delivery.

(2)Unlevered yields represent aggregate returns for 1165 Eastlake Avenue East, an amenity-rich research headquarters for Adaptive Biotechnologies Corporation, and 1208 Eastlake Avenue East, an adjacent multi-tenant office/laboratory building.

(3)We expect to achieve yields greater than 8.0%.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	35
New Class A Development and Redevelopment Properties: Current Projects
---
June 30, 2021
The Arsenal on the Charles	201 Brookline Avenue	840 Winter Street	Alexandria Center® for Life Science –<br><br>South San Francisco(1)
---	---	---	---
Greater Boston/<br>Cambridge/Inner Suburbs	Greater Boston/Fenway	Greater Boston/Route 128	San Francisco Bay Area/South San Francisco
360,545 RSF	510,116 RSF	130,000 RSF	152,148 RSF
92% Leased/Negotiating	84% Leased/Negotiating	73% Leased/Negotiating	100% Leased/Negotiating	Alexandria Center® for Life Science –<br><br>San Carlos	3160 Porter Drive	Alexandria Center® for Life Science –<br><br>Long Island City	3115 Merryfield Row
---	---	---	---
San Francisco Bay Area/Greater Stanford	San Francisco Bay Area/Greater Stanford	New York City/New York City	San Diego/Torrey Pines
216,001 RSF	92,147 RSF	120,027 RSF	146,456 RSF
100% Leased/Negotiating	88% Leased/Negotiating	41% Leased/Negotiating	100% Leased/Negotiating

(1)Image represents 201 Haskins Way in our Alexandria Center® for Life Science – South San Francisco.

| Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021 | 36 | | --- | --- || New Class A Development and Redevelopment Properties: Current Projects (continued) | | --- | | June 30, 2021 || SD Tech by Alexandria(1) | 5505 Morehouse Drive | 10277 Scripps Ranch Boulevard | 9601 and 9603 Medical Center Drive | 9950 Medical Center Drive | | --- | --- | --- | --- | --- | | San Diego/Sorrento Mesa | San Diego/Sorrento Mesa | San Diego/Other | Maryland/Rockville | Maryland/Rockville | | 195,435 RSF | 79,945 RSF | 37,267 RSF | 94,256 RSF | 84,264 RSF | | 100% Leased/Negotiating | 100% Leased/Negotiating | 47% Leased/Negotiating | —% Leased/Negotiating | 100% Leased/Negotiating | | 700 Quince Orchard Road | 20400 Century Boulevard | Alexandria Center® for Life Science – Durham(2) | Alexandria Center® for AgTech | Alexandria Center® for<br><br>Advanced Technologies(3) | | --- | --- | --- | --- | --- | | Maryland/Gaithersburg | Maryland/Gaithersburg | Research Triangle/Research Triangle | Research Triangle/Research Triangle | Research Triangle/Research Triangle | | 169,420 RSF | 80,550 RSF | 325,936 RSF | 160,000 RSF | 250,000 RSF | | 100% Leased/Negotiating | 27% Leased/Negotiating | 77% Leased/Negotiating | 59% Leased/Negotiating | 75% Leased/Negotiating |

(1)Image represents 10055 Barnes Canyon Road in our SD Tech by Alexandria campus.

(2)Image represents 14 TW Alexander Drive in our Alexandria Center® for Life Science – Durham campus.

(3)Image represents 10 Davis Drive in our Alexandria Center® for Advanced Technologies campus.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	37
New Class A Development and Redevelopment Properties: Current Projects (continued)
---
June 30, 2021		Market<br><br>Property/Submarket				Square Footage							Percentage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
	Dev/Redev		In Service		CIP		Total			Leased				Leased/Negotiating				Initial<br><br>Occupancy(1)
Under construction
Greater Boston
The Arsenal on the Charles/Cambridge/Inner Suburbs		Redev		475,743		360,545		836,288			85	%			92	%				2021
201 Brookline Avenue/Fenway		Dev		—		510,116		510,116			18				84					2022
840 Winter Street/Route 128		Redev		30,009		130,000		160,009			19				73					2022
San Francisco Bay Area
Alexandria Center® for Life Science – South San Francisco/South San Francisco		Dev		171,042		152,148		323,190			100				100				2Q21
Alexandria Center® for Life Science – San Carlos/Greater Stanford		Dev		310,177		216,001		526,178			100				100				4Q20
3160 Porter Drive/Greater Stanford		Redev		—		92,147		92,147			21				88					3Q21
New York City
Alexandria Center® for Life Science – Long Island City/New York City		Redev		69,553		120,027		189,580			41				41				4Q20
San Diego
3115 Merryfield Row/Torrey Pines		Dev		—		146,456		146,456			100				100					2022
SD Tech by Alexandria/Sorrento Mesa		Dev		—		195,435		195,435			100				100					2022
5505 Morehouse Drive/Sorrento Mesa		Redev		—		79,945		79,945			100				100					2021
10277 Scripps Ranch Boulevard/Other		Redev		32,774		37,267		70,041			47				47					2022
Seattle
Other		Redev		246,647		213,976		460,623			51				53					2022
Maryland
9601 and 9603 Medical Center Drive/Rockville		Redev		—		94,256		94,256			—				—					2022
9950 Medical Center Drive/Rockville		Dev		—		84,264		84,264			100				100					1H22
700 Quince Orchard Road/Gaithersburg		Redev		—		169,420		169,420			100				100					2021
20400 Century Boulevard/Gaithersburg		Redev		—		80,550		80,550			27				27					2022
Research Triangle
Alexandria Center® for Life Science – Durham/Research Triangle(2)		Redev		326,445		325,936		652,381			77				77				2Q21/2022
Alexandria Center® for AgTech/Research Triangle(3)		Redev/Dev		180,400		160,000		340,400			55				59					2021
Alexandria Center® for Advanced Technologies/Research Triangle		Dev		—		250,000		250,000	(4)		73		(4)		75		(4)		2H21/2022
				1,842,790		3,418,489		5,261,279			69				80
Pre-leased/negotiating near-term projects and key pending acquisition
Charles Park/Greater Boston/Cambridge(5)		Redev		—		400,000		400,000			—				100
4150 Campus Point Court/San Diego/University Town Center		Dev		—		171,102		171,102			100				100
Other near-term projects expected to commence vertical construction in 2021/2022<br><br>(16 properties)(6)		Dev		—		2,982,956		2,982,956			—				87
				—		3,554,058		3,554,058			5				89
				1,842,790		6,972,547		8,815,337			43	%			84	%

(1)Initial occupancy dates are subject to leasing and/or market conditions. Construction disruptions resulting from COVID-19 and observance of social distancing measures may impact construction and occupancy forecasts and will continue to be monitored closely. Multi-tenant projects may have occupancy by tenants over a period of time. Stabilized occupancy may vary depending on single tenancy versus multi-tenancy.

(2)The recently acquired Alexandria Center® for Life Science – Durham redevelopment project includes three properties at 40 Moore Drive, 2400 Ellis Road, and 14 TW Alexander Drive. 2400 Ellis Road is 100% leased and was delivered in 2Q21. We expect stabilized occupancy for the remaining buildings in 2022.

(3)The strategic collaborative agtech campus consists of Phase I at 5 Laboratory Drive, including campus amenities, which was previously delivered, and Phase II at 9 Laboratory Drive.

(4)Represents 150,000 RSF that is 58% leased/negotiating at 8 Davis Drive and 100,000 RSF that is 100% leased at 10 Davis Drive.

(5)We expect to complete this acquisition in December 2021.

(6)Includes 1.8 million RSF related to leases under negotiation/executed letters of intent and 0.8 million RSF related to letters of intent under negotiation.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	38
New Class A Development and Redevelopment Properties: Current Projects (continued)
---
June 30, 2021
(Dollars in thousands)
	Our Ownership Interest															Unlevered Yields
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
Market<br><br>Property/Submarket			In Service		CIP		Cost to Complete				Total at<br>Completion				Initial Stabilized				Initial Stabilized (Cash Basis)
Under construction
Greater Boston
The Arsenal on the Charles/Cambridge/Inner Suburbs	100	%		$	359,079	$	293,274	$	119,647			$	772,000				6.2	%		5.5	%
201 Brookline Avenue/Fenway	98.0	%		—		398,491		335,509				734,000					6.8	%		6.0	%
840 Winter Street/Route 128	100	%		12,973		52,176		TBD
San Francisco Bay Area
Alexandria Center® for Life Science – South San Francisco/South San Francisco	100	%		177,921		149,407		42,672				370,000					6.4	%		6.2	%
Alexandria Center® for Life Science – San Carlos/Greater Stanford	100	%		388,369		170,932		70,699				630,000					6.4	%		6.1	%
3160 Porter Drive/Greater Stanford	100	%		—		86,951		20,049				107,000					5.2	%		5.0	%
New York City
Alexandria Center® for Life Science – Long Island City/New York City	100	%		52,421		117,509		14,370				184,300					5.5	%		5.6	%
San Diego
3115 Merryfield Row/Torrey Pines	100	%		—		87,222		64,778				152,000					6.2	%		6.2	%
SD Tech by Alexandria/Sorrento Mesa	50.0	%		—		45,291		135,709				181,000					7.2	%		6.6	%
5505 Morehouse Drive/Sorrento Mesa	100	%		—		28,001		38,999				67,000					6.9	%		7.0	%
10277 Scripps Ranch Boulevard/Other	100	%		11,786		13,433		TBD
Seattle
Other	100	%		54,321		66,492		TBD
Maryland
9601 and 9603 Medical Center Drive/Rockville	100	%		—		28,121		TBD
9950 Medical Center Drive/Rockville	100	%		—		41,297		18,303				59,600					8.6	%		7.7	%
700 Quince Orchard Road/Gaithersburg	100	%		—		50,977		28,523				79,500					8.6	%		7.3	%
20400 Century Boulevard/Gaithersburg	100	%		—		9,824		TBD
Research Triangle
Alexandria Center® for Life Science – Durham/Research Triangle	100	%		88,265		73,127		83,608				245,000					7.5	%		6.7	%
Alexandria Center® for AgTech/Research Triangle	100	%		91,175		83,057		18,768				193,000					7.1	%		7.0	%
Alexandria Center® for Advanced Technologies/Research Triangle	100	%		—		63,404		87,596				151,000					7.5	%		7.3	%
				$	1,236,310	$	1,858,986	$	1,290,000	(1)		$	4,390,000	(1)

(1)Amounts rounded to the nearest $10 million.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	39
New Class A Development and Redevelopment Properties: Summary of Pipeline
---
June 30, 2021
(Dollars in thousands)
Market<br><br>Property/Submarket	Our Ownership Interest			Book Value			Square Footage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
			Development and Redevelopment
			Under Construction			Near<br>Term		Intermediate<br>Term		Future		Total
Greater Boston
The Arsenal on the Charles/Cambridge/Inner Suburbs	100	%		$	320,937		360,545		200,000		—		12,502		573,047
Alexandria Center® for Life Science – Fenway/Fenway	(1)			522,662			510,116		—		305,000		—		815,116
840 Winter Street/Route 128	100	%		52,176			130,000		—		—		—		130,000
325 Binney Street/Cambridge	100	%		181,094			—		450,000		—		—		450,000
57 Coolidge Avenue/Cambridge/Inner Suburbs	75.0	%		50,620			—		275,000		—		—		275,000
15 Necco Street/Seaport Innovation District	93.7	%		196,456			—		350,000		—		—		350,000
Reservoir Woods/Route 128	100	%		45,592			—		202,428		—		752,845		955,273	(2)
10 Necco Street/Seaport Innovation District	100	%		92,731			—		—		175,000		—		175,000
215 Presidential Way/Route 128	100	%		6,808			—		—		112,000		—		112,000
550 Arsenal Street/Cambridge/Inner Suburbs	100	%		54,285			—		—		—		775,000		775,000	(2)
Alexandria Technology Square®/Cambridge	100	%		7,881			—		—		—		100,000		100,000
380 and 420 E Street/Seaport Innovation District	100	%		118,560			—		—		—		1,000,000		1,000,000	(2)
99 A Street/Seaport Innovation District	95.0	%		45,940			—		—		—		235,000		235,000
One Upland Road, 100 Tech Drive, and One Investors Way/Route 128	100	%		13,769			—		—		—		1,100,000		1,100,000
231 Second Avenue/Route 128	100	%		1,093			—		—		—		32,000		32,000
Other value-creation projects	100	%		9,988			—		—		—		16,955		16,955
				1,720,592			1,000,661		1,477,428		592,000		4,024,302		7,094,391
San Francisco Bay Area
Alexandria Center® for Life Science – South San Francisco/<br><br>South San Francisco	100	%		149,407			152,148		—		—		—		152,148
Alexandria Center® for Life Science – San Carlos/Greater Stanford	100	%		439,612			216,001		—		700,000		587,000	(2)	1,503,001
3160 Porter Drive/Greater Stanford	100	%		86,951			92,147		—		—		—		92,147
Alexandria Technology Center® – Gateway/South San Francisco	46.8	%		70,219			—		517,010	(2)	—		291,000		808,010
901 California Avenue/Greater Stanford	100	%		1,680			—		56,924		—		—		56,924
88 Bluxome Street/SoMa	100	%		313,432			—		1,070,925		—		—		1,070,925
1450 Owens Street/Mission Bay	100	%		60,904			—		—		191,000		—		191,000
3825 and 3875 Fabian Way/Greater Stanford	100	%		—			—		—		250,000		228,000		478,000	(2)
3450 and 3460 Hillview Avenue/Greater Stanford	100	%		—			—		—		76,951		—		76,951	(2)
East Grand Avenue/South San Francisco	30.0	%		6,103			—		—		—		90,000		90,000
2475 Hanover Street/Greater Stanford	100	%		—			—		—		—		83,980		83,980	(2)
Other value-creation projects	100	%		—			—		—		—		25,000		25,000
				$	1,128,308		460,296		1,644,859		1,217,951		1,304,980		4,628,086
(1)We have a 98.0% ownership interest in 201 Brookline Avenue, which is currently under construction. We have a 100% ownership interest in the intermediate-term development project.<br><br>(2)Represents total square footage upon completion of development or redevelopment of a new Class A property. Square footage presented includes RSF of buildings currently in operation at properties that also have inherent future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property and commence future construction. Refer to “Definitions and reconciliations” of this Supplemental Information for additional details on value-creation square feet currently included in rental properties.																	Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	40
---	---
New Class A Development and Redevelopment Properties: Summary of Pipeline (continued)
---
June 30, 2021
(Dollars in thousands)
Market<br><br>Property/Submarket	Our Ownership Interest			Book Value			Square Footage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
			Development and Redevelopment
			Under Construction			Near<br>Term		Intermediate<br>Term		Future		Total
New York City
Alexandria Center® for Life Science – Long Island City/New York City	100	%		$	117,509		120,027		—		—		—		120,027
47-50 30th Street/New York City	100	%		30,094			—		135,938		—		—		135,938
Alexandria Center® for Life Science – New York City/New York City	100	%		66,556			—		—		550,000	(1)	—		550,000
219 East 42nd Street/New York City	100	%		—			—		—		—		579,947		579,947	(2)
				214,159			120,027		135,938		550,000		579,947		1,385,912
San Diego
3115 Merryfield Row/Torrey Pines	100	%		87,222			146,456		—		—		—		146,456
SD Tech by Alexandria/Sorrento Mesa	50.0	%		131,727			195,435		190,074		160,000		333,845		879,354
5505 Morehouse Drive/Sorrento Mesa	100	%		28,001			79,945		—		—		—		79,945
10277 Scripps Ranch Boulevard/Other	100	%		13,433			37,267		32,774	(2)	—		—		70,041
11255 and 11355 North Torrey Pines Road/Torrey Pines	100	%		109,564			—		288,956		—		—		288,956	(2)
10931 and 10933 North Torrey Pines Road/Torrey Pines	100	%		—			—		242,000		—		—		242,000	(2)
Alexandria Point/University Town Center	55.0	%		108,620			—		596,102		—		324,445	(2)	920,547
University District/University Town Center	100	%		61,401			—		—		600,000	(3)	—		600,000	(2)
10975 and 10995 Torreyana Road/Torrey Pines	100	%		48,250			—		—		—		125,280		125,280	(2)
5200 Illumina Way/University Town Center	51.0	%		12,632			—		—		—		451,832		451,832
Sequence District by Alexandria/Sorrento Mesa	100	%		37,383			—		—		—		1,798,915		1,798,915	(2)
9444 Waples Street/Sorrento Mesa	100	%		—			—		—		—		149,000		149,000	(2)
4045 and 4075 Sorrento Valley Boulevard/Sorrento Valley	100	%		7,667			—		—		—		149,000		149,000	(2)
Other value-creation projects	100	%		6,876			—		54,000		—		50,000		104,000
				652,776			459,103		1,403,906		760,000		3,382,317		6,005,326
Seattle
1150 Eastlake Avenue East/Lake Union	100	%		78,423			—		310,000		—		—		310,000
701 Dexter Avenue North/Lake Union	100	%		61,971			—		217,000		—		—		217,000
601 Dexter Avenue North/Lake Union	100	%		36,510			—		—		—		188,400		188,400	(2)
1010 4th Avenue South/SoDo	100	%		50,315			—		—		—		544,825		544,825
830 4th Avenue South/SoDo	100	%		—			—		—		—		52,488		52,488	(2)
Other value-creation projects	100	%		72,483			213,976		51,255	(2)	—		35,000		300,231
				$	299,702		213,976		578,255		—		820,713		1,612,944
(1)We are currently negotiating a long-term ground lease with the City of New York for the future site of a new building approximating 550,000 RSF.<br><br>(2)Represents total square footage upon completion of development or redevelopment of a new Class A property. Square footage presented includes RSF of buildings currently in operation at properties that also have inherent future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property and commence future construction. Refer to “Definitions and reconciliations” of this Supplemental Information for additional details on value-creation square feet currently included in rental properties.<br><br>(3)Includes our recently acquired properties at 4555 Executive Drive and 9363, 9373, and 9393 Towne Centre Drive in our University Town Center submarket, which are currently under evaluation for development, subject to future market conditions.																	Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	41
---	---
New Class A Development and Redevelopment Properties: Summary of Pipeline (continued)
---
June 30, 2021
(Dollars in thousands)
Market<br><br>Property/Submarket	Our Ownership Interest			Book Value			Square Footage
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
			Development and Redevelopment
			Under Construction			Near<br>Term		Intermediate<br>Term		Future		Total
Maryland
9601 and 9603 Medical Center Drive and Excess Land/Rockville	100	%		$	42,465		94,256		—		—		258,000	352,256
9950 Medical Center Drive/Rockville	100	%		41,297			84,264		—		—		—	84,264
700 Quince Orchard Road/Gaithersburg	100	%		50,977			169,420		—		—		—	169,420
20400 Century Boulevard/Gaithersburg	100	%		9,824			80,550		—		—		—	80,550
Alexandria Center® at Traville Gateway/Rockville	100	%		30,681			—		410,000		—		70,000	480,000
9808 Medical Center Drive/Rockville	100	%		5,701			—		90,000		—		—	90,000
				180,945			428,490		500,000		—		328,000	1,256,490
Research Triangle
Alexandria Center® for Life Science – Durham/Research Triangle	100	%		115,791			325,936		—		—		885,000	1,210,936
Alexandria Center® for Advanced Technologies/Research Triangle	100	%		81,525			250,000		—		70,000		700,000	1,020,000
Alexandria Center® for AgTech, Phase II/Research Triangle	100	%		83,057			160,000		—		—		—	160,000
Other value-creation projects	100	%		4,185			—		—		—		76,262	76,262
				284,558			735,936		—		70,000		1,661,262	2,467,198
Other value-creation projects	100	%		60,556			—		—		—		972,200	972,200
Total pipeline as of June 30, 2021				$	4,541,596		3,418,489		5,740,386		3,189,951		13,073,721	25,422,547	(1)
Key pending acquisitions
Charles Park/Cambridge(2)							—		400,000		—		—	400,000
Mercer Mega Block/Lake Union							—		800,000		—		—	800,000
							3,418,489		6,940,386		3,189,951		13,073,721	26,622,547

(1)Total square footage includes 3,972,551 RSF of buildings currently in operation that will be redeveloped or replaced with new development RSF upon commencement of future construction. Refer to “Definitions and reconciliations” of this Supplemental Information for additional details on value-creation square feet currently included in rental properties.

(2)We expect to complete this acquisition in December 2021.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	42
Construction Spending
---
June 30, 2021
(In thousands)
	Six Months Ended
---	---	---
Construction Spending	June 30, 2021
Additions to real estate – consolidated projects	$	1,001,983
Investments in unconsolidated real estate joint ventures		720
Contributions from noncontrolling interests		(30,138)
Construction spending (cash basis)		972,565
Change in accrued construction		20,451
Construction spending		993,016
Projected construction spending for the six months ending December 31, 2021		916,984
Guidance midpoint	$	1,910,000	Year Ending
---	---	---
Projected Construction Spending	December 31, 2021
Development, redevelopment, and pre-construction projects(1)	$	1,790,000
Contributions from noncontrolling interests (consolidated real estate joint ventures)		(100,000)
Revenue-enhancing and repositioning capital expenditures		155,000
Non-revenue-enhancing capital expenditures		65,000
Guidance midpoint	$	1,910,000

(1)Refer to “Development, redevelopment, and pre-construction” in the “Definitions and reconciliations” of this Supplemental Information for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	43
Joint Venture Financial Information
---
June 30, 2021
Consolidated Real Estate Joint Ventures
---	---	---	---	---	---	---	---	---	---
Property	Market	Submarket	Noncontrolling<br><br>Interest Share(1)				Operating RSF<br><br>at 100%
75/125 Binney Street	Greater Boston	Cambridge/Inner Suburbs		60.0%				388,270
225 Binney Street	Greater Boston	Cambridge/Inner Suburbs		70.0%				305,212
57 Coolidge Avenue	Greater Boston	Cambridge/Inner Suburbs		25.0%				—	(2)
409 and 499 Illinois Street	San Francisco Bay Area	Mission Bay		40.0%				455,069
1500 Owens Street	San Francisco Bay Area	Mission Bay		49.9%				158,267
Alexandria Technology Center® – Gateway(3)	San Francisco Bay Area	South San Francisco		53.2%				1,089,852
213 East Grand Avenue	San Francisco Bay Area	South San Francisco		70.0%				300,930
500 Forbes Boulevard	San Francisco Bay Area	South San Francisco		90.0%				155,685
Alexandria Center® for Life Science – Millbrae Station	San Francisco Bay Area	South San Francisco		63.0%				—
Alexandria Point(4)	San Diego	University Town Center		45.0%				1,337,916
5200 Illumina Way	San Diego	University Town Center		49.0%				792,687
9625 Towne Centre Drive	San Diego	University Town Center		49.9%				163,648
SD Tech by Alexandria(5)	San Diego	Sorrento Mesa		50.0%				677,597
The Eastlake Life Science Campus by Alexandria(6)	Seattle	Lake Union		70.0%				321,218
Unconsolidated Real Estate Joint Ventures
Property	Market	Submarket	Our Ownership Share(7)				Operating RSF<br><br>at 100%
1655 and 1725 Third Street	San Francisco Bay Area	Mission Bay		10.0	%			586,208
Menlo Gateway	San Francisco Bay Area	Greater Stanford		49.0	%			772,983
1401/1413 Research Boulevard	Maryland	Rockville		65.0	%	(8)		(9)

(1)In addition to the consolidated real estate joint ventures listed, various partners hold insignificant noncontrolling interests in five other real estate joint ventures in North America.

(2)We expect to commence vertical construction of 275,000 RSF during 2021.

(3)Includes 601, 611, 651, 681, 685, and 701 Gateway Boulevard in our South San Francisco submarket. Noncontrolling interest share is anticipated to be 49% as we make further contributions into the joint venture over time.

(4)Includes 10210, 10260, 10290, and 10300 Campus Point Drive and 4161, 4224, and 4242 Campus Point Court in our University Town Center submarket.

(5)Includes 9605, 9645, 9675, 9685, 9725, 9735, 9808, 9855, and 9868 Scranton Road 10055 and 10065 Barnes Canyon Road in our Sorrento Mesa submarket.

(6)Includes 1201 and 1208 Eastlake Avenue East and 199 East Blaine Street in our Lake Union submarket.

(7)In addition to the unconsolidated real estate joint ventures listed, we hold an interest in one other insignificant unconsolidated real estate joint venture in North America.

(8)Represents our ownership interest; our voting interest is limited to 50%.

(9)Joint venture with a distinguished retail real estate developer for an approximate 90,000 RSF retail shopping center.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	44
Joint Venture Financial Information (continued)
---
June 30, 2021
(Dollars in thousands)
		As of June 30, 2021
---	---	---	---	---
	Noncontrolling Interest <br>Share of Consolidated <br>Real Estate JVs		Our Share of <br>Unconsolidated Real <br>Estate JVs
Investments in real estate	$	1,795,944	$	478,137
Cash, cash equivalents, and restricted cash		61,225		7,237
Other assets		228,471		61,995
Secured notes payable (refer to page 49)		—		(219,705)
Other liabilities		(94,845)		(4,042)
Redeemable noncontrolling interests		(11,567)		—
	$	1,979,228	$	323,622
	Noncontrolling Interest Share of <br>Consolidated Real Estate JVs				Our Share of Unconsolidated <br>Real Estate JVs
---	---	---	---	---	---	---	---	---
	June 30, 2021				June 30, 2021
	Three Months Ended		Six Months Ended		Three Months Ended		Six Months Ended
Total revenues	$	48,353	$	93,115	$	12,207	$	22,719
Rental operations		(12,613)		(24,628)		(2,279)		(3,825)
		35,740		68,487		9,928		18,894
General and administrative		(223)		(332)		(124)		(154)
Interest		—		—		(3,060)		(5,383)
Depreciation and amortization		(16,301)		(31,744)		(4,135)		(7,211)
Fixed returns allocated to redeemable noncontrolling interests(1)		220		437		—		—
	$	19,436	$	36,848	$	2,609	$	6,146
Straight-line rent and below-market lease revenue	$	1,227	$	2,082	$	1,117	$	2,115
Funds from operations(2)	$	35,737	$	68,592	$	6,744	$	13,357

(1)Represents an allocation of joint venture earnings to redeemable noncontrolling interests primarily in one property in our South San Francisco submarket. These redeemable noncontrolling interests earn a fixed return on their investment rather than participate in the operating results of the property.

(2)Refer to “Funds from operations and funds from operations per share” in our Earnings Press Release and “Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders” in “Definitions and reconciliations” of this Supplemental Information for the definition and reconciliation from the most directly comparable financial measure presented in accordance with GAAP.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	45
Investments
---
June 30, 2021
(Dollars in thousands)

We present our equity investments at fair value whenever fair value or net asset value (“NAV”) is readily available. Adjustments for our limited partnership investments represent changes in reported NAV as a practical expedient to estimate fair value. For investments without readily available fair values, we adjust the carrying amount whenever such investments have an observable price change, and further adjustments are not made until another price change, if any, is observed. Refer to “Investments” in the “Definitions and reconciliations” of this Supplemental Information for additional details.

	June 30, 2021
	Three Months Ended			Six Months Ended			Year Ended December 31, 2020
Realized gains	$	60,232	(1)	$	107,497	(2)	$	47,288	(3)
Unrealized gains	244,031			197,780			374,033
Investment income	$	304,263		$	305,277		$	421,321
	June 30, 2021
---	---	---	---	---	---	---	---	---
Investments	Cost		Unrealized<br>Gains			Carrying Amount
Publicly traded companies	$	226,831	$	401,095	(4)	$	627,926
Entities that report NAV	362,020		466,065			828,085
Entities that do not report NAV:
Entities with observable price changes	57,237		94,341			151,578
Entities without observable price changes	343,646		—			343,646
Investments held at adjusted carrying value or fair value	$	989,734	$	961,501		1,951,235
Investments accounted for under the equity method of accounting						48,048
Total investments						$	1,999,283	(5)

(1)Includes realized gains of $34.8 million related to the sales of our investments in two publicly traded biotechnology companies.

(2)Includes realized gains of $57.7 million related to the acquisition of one of our privately held non-real estate investments in a biopharmaceutical company by a pharmaceutical company and the sales of investments in two publicly traded biotechnology companies.

(3)Includes impairments of $24.5 million related to investments in privately held entities that do not report NAV.

(4)Includes gross unrealized gains and losses of $416.0 million and $14.9 million, respectively, as of June 30, 2021.

(5)Represents 3.4% of total gross assets as of June 30, 2021.

Public/Private<br>Mix (Cost)
Tenant/Non-Tenant<br>Mix (Cost)
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	46
---	---
Key Credit Metrics
---
June 30, 2021
Liquidity		Minimal Outstanding Borrowings and Significant Availability on Unsecured Senior Line of Credit
---	---	---
		(in millions)
4.5B
(in millions)
Availability under our unsecured senior line of credit, net of amounts outstanding under our commercial paper program	2,700
Outstanding forward equity sales agreements(1)
Cash, cash equivalents, and restricted cash
Investments in publicly traded companies
Liquidity as of June 30, 2021	4,464
Net Debt and Preferred Stock to Adjusted EBITDA(2)		Fixed-Charge Coverage Ratio(2)

All values are in US Dollars.

(1)Represents expected net proceeds from the future settlement of the remaining 4.6 million shares outstanding under our forward equity sales agreements as of June 30, 2021.

(2)Quarter annualized. Refer to “Fixed-charge coverage ratio” and “Net debt and preferred stock to Adjusted EBITDA” in the “Definitions and reconciliations” of this Supplemental Information for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	47
Summary of Debt
---
June 30, 2021
(in millions)

Weighted-Average Remaining Term of 12.5 Years

(1)Refer to footnote 2 on the next page under “Fixed-rate and variable-rate debt” for additional details.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	48
Summary of Debt (continued)
---
June 30, 2021
(Dollars in thousands)
Fixed-rate and variable-rate debt	Fixed-Rate<br>Debt			Variable-Rate Debt			Total				Percentage			Weighted-Average
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
										Interest Rate(1)			Remaining Term<br>(in years)
Secured notes payable	$	227,984		$	—		$	227,984			2.6	%		3.54	%	2.9
Unsecured senior notes payable	8,313,025			—			8,313,025				94.0			3.54		13.1
Unsecured senior line of credit	—			—			—				—			N/A		4.5
Commercial paper program	—			299,990			299,990				3.4			0.23		(2)
Total/weighted average	$	8,541,009		$	299,990		$	8,840,999			100.0	%		3.43	%	12.5	(2)
Percentage of total debt	97		%	3		%	100		%

(1)Represents the weighted-average interest rate as of the end of the applicable period, including expense/income related to the amortization of loan fees, amortization of debt premiums (discounts), and other bank fees.

(2)The commercial paper notes bear interest at short-term fixed rates and can generally be issued with a maturity of 30 days or less and with a maximum maturity of 397 days from the date of issuance. Borrowings under the program are used to fund short-term capital needs and are backed by our unsecured senior line of credit. The commercial paper outstanding as of June 30, 2021, matured on July 7, 2021. In the event we are unable to issue commercial paper notes or refinance outstanding borrowings under terms equal to or more favorable than those under our unsecured senior line of credit, we expect to borrow under the unsecured senior line of credit at L+0.815%. As such, we calculate the weighted-average remaining term of our commercial paper by using the maturity date of our unsecured senior line of credit. Using the maturity date of our outstanding commercial paper, the consolidated weighted-average maturity of our debt is 12.4 years. The commercial paper notes sold during the three months ended June 30, 2021, were issued at a weighted-average yield to maturity of 0.20% and had a weighted-average maturity term of 8 days.

Debt covenants	Unsecured Senior Notes Payable		Unsecured Senior Line of Credit
Debt Covenant Ratios(1)	Requirement	June 30, 2021	Requirement	June 30, 2021
Total Debt to Total Assets	≤ 60%	31%	≤ 60.0%	28.1%
Secured Debt to Total Assets	≤ 40%	1%	≤ 45.0%	0.7%
Consolidated EBITDA to Interest Expense	≥ 1.5x	10.4x	≥ 1.50x	4.15x
Unencumbered Total Asset Value to Unsecured Debt	≥ 150%	301%	N/A	N/A
Unsecured Interest Coverage Ratio	N/A	N/A	≥ 1.75x	8.21x

(1)All covenant ratio titles utilize terms as defined in the respective debt and credit agreements. The calculation of consolidated EBITDA is based on the definitions contained in our loan agreements and is not directly comparable to the computation of EBITDA as described in Exchange Act Release No. 47226.

Unconsolidated real estate joint ventures’ debt
Unconsolidated Joint Venture	Our Share		Maturity Date	Stated Rate	Interest Rate(1)				Debt Balance at 100%(2)
1401/1413 Research Boulevard		65.0%	5/17/22	L+2.50%		3.50	%	(3)	$	26,921
1655 and 1725 Third Street		10.0%	3/10/25	4.50%		4.57	%		598,444
Menlo Gateway, Phase II		49.0%	5/1/35	4.53%		4.59	%		155,579
Menlo Gateway, Phase I		49.0%	8/10/35	4.15%		4.18	%		138,245
									$	919,189

(1)Includes interest expense and amortization of loan fees.

(2)Represents outstanding principal, net of unamortized deferred financing costs, as of June 30, 2021.

(3)This loan is subject to a fixed floor rate of 3.5%.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	49
Summary of Debt (continued)
---
June 30, 2021
(Dollars in thousands)
Debt	Stated <br>Rate			Interest<br><br>Rate(1)			Maturity<br><br>Date(2)		Principal Payments Remaining for the Periods Ending December 31,												Principal		Unamortized (Deferred Financing Cost), (Discount)/Premium		Total
---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---	---
						2021		2022		2023		2024		2025		Thereafter
Secured notes payable
Greater Boston	4.82	%		3.40	%		2/6/24		$	1,705	$	3,564	$	3,742	$	183,527	$	—	$	—	$	192,538	$	7,059	$	199,597
San Francisco Bay Area	4.14	%		4.42			7/1/26		—		—		—		—		—		28,200		28,200		(517)		27,683
San Francisco Bay Area	6.50	%		6.50			7/1/36		26		28		30		32		34		554		704		—		704
Secured debt weighted-average interest rate/subtotal	4.74	%		3.54					1,731		3,592		3,772		183,559		34		28,754		221,442		6,542		227,984
Commercial paper program(3)	0.23	%	(3)	0.23		(3)	(3)		—		—		—		—		—		300,000		300,000		(10)		299,990
Unsecured senior line of credit	L+0.815	%	(4)	N/A			1/6/26		—		—		—		—		—		—		—		—		—
Unsecured senior notes payable	3.45	%		3.62			4/30/25		—		—		—		—		600,000		—		600,000		(3,369)		596,631
Unsecured senior notes payable	4.30	%		4.50			1/15/26		—		—		—		—		—		300,000		300,000		(2,225)		297,775
Unsecured senior notes payable – green bond	3.80	%		3.96			4/15/26		—		—		—		—		—		350,000		350,000		(2,358)		347,642
Unsecured senior notes payable	3.95	%		4.13			1/15/27		—		—		—		—		—		350,000		350,000		(2,815)		347,185
Unsecured senior notes payable	3.95	%		4.07			1/15/28		—		—		—		—		—		425,000		425,000		(2,777)		422,223
Unsecured senior notes payable	4.50	%		4.60			7/30/29		—		—		—		—		—		300,000		300,000		(1,799)		298,201
Unsecured senior notes payable	2.75	%		2.87			12/15/29		—		—		—		—		—		400,000		400,000		(3,486)		396,514
Unsecured senior notes payable	4.70	%		4.81			7/1/30		—		—		—		—		—		450,000		450,000		(3,351)		446,649
Unsecured senior notes payable	4.90	%		5.05			12/15/30		—		—		—		—		—		700,000		700,000		(7,455)		692,545
Unsecured senior notes payable	3.375	%		3.48			8/15/31		—		—		—		—		—		750,000		750,000		(6,581)		743,419
Unsecured senior notes payable – green bond	2.00	%		2.12			5/18/32		—		—		—		—		—		900,000		900,000		(10,165)		889,835
Unsecured senior notes payable	1.875	%		1.97			2/1/33		—		—		—		—		—		1,000,000		1,000,000		(10,131)		989,869
Unsecured senior notes payable	4.85	%		4.93			4/15/49		—		—		—		—		—		300,000		300,000		(3,274)		296,726
Unsecured senior notes payable	4.00	%		3.91			2/1/50		—		—		—		—		—		700,000		700,000		10,364		710,364
Unsecured senior notes payable	3.00	%		3.08			5/18/51		—		—		—		—		—		850,000		850,000		(12,553)		837,447
Unsecured debt weighted average/subtotal				3.42					—		—		—		—		600,000		8,075,000		8,675,000		(61,985)		8,613,015
Weighted-average interest rate/total				3.43	%				$	1,731	$	3,592	$	3,772	$	183,559	$	600,034	$	8,103,754	$	8,896,442	$	(55,443)	$	8,840,999
Balloon payments									$	—	$	—	$	—	$	183,221	$	600,000	$	8,103,200	$	8,886,421	$	—	$	8,886,421
Principal amortization									1,731		3,592		3,772		338		34		554		10,021		(55,443)		(45,422)
Total debt									$	1,731	$	3,592	$	3,772	$	183,559	$	600,034	$	8,103,754	$	8,896,442	$	(55,443)	$	8,840,999
Fixed-rate debt									$	1,731	$	3,592	$	3,772	$	183,559	$	600,034	$	7,803,754	$	8,596,442	$	(55,433)	$	8,541,009
Variable-rate debt									—		—		—		—		—		300,000		300,000		(10)		299,990
Total debt									$	1,731	$	3,592	$	3,772	$	183,559	$	600,034	$	8,103,754	$	8,896,442	$	(55,443)	$	8,840,999
Weighted-average stated rate on maturing debt									N/A		N/A		N/A		4.82%		3.45%		3.32%

(1)Represents the weighted-average interest rate as of the end of the applicable period, including amortization of loan fees, amortization of debt premiums (discounts), and other bank fees.

(2)Reflects any extension options that we control.

(3)Refer to footnote 2 on the prior page under “Fixed-rate and variable-rate debt.”

(4)During the year ended December 31, 2020, we achieved certain sustainability measures, as described in our unsecured senior line of credit agreement, which reduced the borrowing rate by one basis point for one year ending December 31, 2021.

Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	50
Definitions and Reconciliations
---
June 30, 2021

This section contains additional details for sections throughout this Supplemental Information and the accompanying Earnings Press Release, as well as explanations and reconciliations of certain non-GAAP financial measures and the reasons why we use these supplemental measures of performance and believe they provide useful information to investors. Additional detail can be found in our most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q, as well as other documents filed with or furnished to the SEC from time to time.

Adjusted EBITDA and Adjusted EBITDA margin

The following table reconciles net income (loss) and revenues, the most directly comparable financial measures calculated and presented in accordance with GAAP, to Adjusted EBITDA and revenues, as adjusted, respectively:

	Three Months Ended
(Dollars in thousands)	6/30/21		3/31/21		12/31/20		9/30/20		6/30/20
Net income	$	404,520	$	25,533	$	457,133	$	95,799	$	243,561
Interest expense	35,158		36,467		37,538		43,318		45,014
Income taxes	2,800		1,426		2,053		2,430		1,406
Depreciation and amortization	190,052		180,913		177,750		176,831		168,027
Stock compensation expense	12,242		12,446		11,394		12,994		9,185
Loss on early extinguishment of debt	—		67,253		7,898		52,770		—
Gain on sales of real estate	—		(2,779)		(152,503)		(1,586)		—
Realized gains on non-real estate investments	(34,773)		(22,919)		—		—		—
Unrealized (gains) losses on non-real estate investments	(244,031)		46,251		(233,538)		14,013		(171,652)
Impairment of real estate	4,926		5,129		25,177		7,680		13,218
Impairment of non-real estate investments	—		—		—		—		4,702
Termination fee	—		—		—		(86,179)		—
Adjusted EBITDA	$	370,894	$	349,720	$	332,902	$	318,070	$	313,461
Revenues	$	509,619	$	479,849	$	463,720	$	545,042	$	436,956
Non-real estate investments – realized gains	60,232		47,265		21,599		17,361		13,005
Realized gains on non-real estate investments	(34,773)		(22,919)		—		—		—
Impairment of non-real estate investments	—		—		—		—		4,702
Termination fee	—		—		—		(86,179)		—
Revenues, as adjusted	$	535,078	$	504,195	$	485,319	$	476,224	$	454,663
Adjusted EBITDA margin	69%		69%		69%		67%		69%

We use Adjusted EBITDA as a supplemental performance measure of our operations, for financial and operational decision-making, and as a supplemental means of evaluating period-to-period comparisons on a consistent basis. Adjusted EBITDA is calculated as earnings before interest, taxes, depreciation, and amortization (“EBITDA”), excluding stock compensation expense, gains or losses on early extinguishment of debt, gains or losses on sales of real estate, impairments of real estate, and significant termination fees. Adjusted EBITDA also excludes unrealized gains or losses and significant realized gains and impairments that result from our non-real estate investments. These non-real estate investment amounts are classified in our consolidated statements of operations outside of total revenues.

We believe Adjusted EBITDA provides investors with relevant and useful information as it allows investors to evaluate the operating performance of our business activities without having to account for differences recognized because of investing and financing decisions related to our real estate and non-real estate investments, our capital structure, capital market transactions, and variances resulting from the volatility of market conditions outside of our control. For example, we exclude gains or losses on the early extinguishment of debt to allow investors to measure our performance independent of our indebtedness and capital structure. We believe that adjusting for the effects of impairments and gains or losses on sales of real estate, significant impairments and gains on the sale of non-real estate investments, and significant termination fees allows investors to evaluate performance from period to period on a consistent basis without having to account for differences recognized because of investing and financing decisions related to our real estate and non-real estate investments or other corporate activities that may not be representative of the operating performance of our properties.

In addition, we believe that excluding charges related to stock compensation and unrealized gains or losses facilitates for investors a comparison of our business activities across periods without the volatility resulting from market forces outside of our control. Adjusted EBITDA has limitations as a measure of our performance. Adjusted EBITDA does not reflect our historical expenditures or future requirements for capital expenditures or contractual commitments. While Adjusted EBITDA is a relevant measure of performance, it does not represent net income (loss) or cash flows from operations calculated and presented in accordance with GAAP, and it should not be considered as an alternative to those indicators in evaluating performance or liquidity.

In order to calculate Adjusted EBITDA margin, we also make comparable adjustments to our revenues. We adjust our total revenues by realized gains, losses, and impairments related to our non-real estate investments and significant termination fees to arrive at revenues, as adjusted. Our calculation of Adjusted EBITDA margin divides Adjusted EBITDA by our revenues, as adjusted. We believe that consistent application of these comparable adjustments to both components of Adjusted EBITDA margin provides a more useful calculation for the comparison across periods.

Annual rental revenue

Annual rental revenue represents the annualized fixed base rental obligations, calculated in accordance with GAAP, for leases in effect as of the end of the period, related to our operating RSF. Annual rental revenue is presented using 100% of the annual rental revenue of our consolidated properties and our share of annual rental revenue for our unconsolidated real estate joint ventures. Annual rental revenue per RSF is computed by dividing annual rental revenue by the sum of 100% of the RSF of our consolidated properties and our share of the RSF of properties held in unconsolidated real estate joint ventures. As of June 30, 2021, approximately 94% of our leases (on an RSF basis) were triple net leases, which require tenants to pay substantially all real estate taxes, insurance, utilities, repairs and maintenance, common area expenses, and other operating expenses (including increases thereto) in addition to base rent. Annual rental revenue excludes these operating expenses recovered from our tenants. Amounts recovered from our tenants related to these operating expenses, along with base rent, are classified in income from rentals in our consolidated statements of operations.

Cash interest

Cash interest is equal to interest expense calculated in accordance with GAAP plus capitalized interest, less amortization of loan fees and debt premiums (discounts). Refer to the definition of fixed-charge coverage ratio for a reconciliation of interest expense, the most directly comparable financial measure calculated and presented in accordance with GAAP, to cash interest.

Class A properties and AAA locations

Class A properties are properties clustered in AAA locations that provide innovative tenants with highly dynamic and collaborative environments that enhance their ability to successfully recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. Class A properties generally command higher annual rental rates than other classes of similar properties.

AAA locations are in close proximity to concentrations of specialized skills, knowledge, institutions, and related businesses. Such locations are generally characterized by high barriers to entry for new landlords, high barriers to exit for tenants, and a limited supply of available space.

Development, redevelopment, and pre-construction

A key component of our business model is our disciplined allocation of capital to the development and redevelopment of new Class A properties, and property enhancements identified during the underwriting of certain acquired properties, located in collaborative life science, agtech, and technology campuses in AAA innovation clusters. These projects are generally focused on providing high-quality, generic, and reusable spaces that meet the real estate requirements of, and are reusable by, a wide range of tenants. Upon completion, each value-creation project is expected to generate a significant increase in rental income, net operating income, and cash flows. Our development and redevelopment projects are generally in locations that are highly desirable to high-quality entities, which we believe results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value.

Development projects generally consist of the ground-up development of generic and reusable facilities. Redevelopment projects consist of the permanent change in use of office, warehouse, and shell space into office/laboratory, agtech, or tech office space. We generally will not commence new development projects for aboveground construction of new Class A office/laboratory, agtech, and tech office space without first securing significant pre-leasing for such space, except when there is solid market demand for high-quality Class A properties.

Pre-construction activities include entitlements, permitting, design, site work, and other activities preceding commencement of construction of aboveground building improvements. The advancement of pre-construction efforts is focused on reducing the time required to deliver projects to prospective tenants. These critical activities add significant value for future ground-up development and are required for the vertical construction of buildings. Ultimately, these projects will provide high-quality facilities and are expected to generate significant revenue and cash flows.

Development, redevelopment, and pre-construction spending also includes the following costs: (i) certain tenant improvements and renovations that will be reimbursed, (ii) amounts to bring certain acquired properties up to market standard and/or other costs identified during the acquisition process (generally within two years of acquisition), and (iii) permanent conversion of space for highly flexible, move-in-ready office/laboratory space to foster the growth of promising early- and growth-stage life science companies.

Revenue-enhancing and repositioning capital expenditures represent spending to reposition or significantly change the use of a property, including through improvement in the asset quality from Class B to Class A.

Non-revenue-enhancing capital expenditures represent costs required to maintain the current revenues of a stabilized property, including the associated costs for renewed and re-leased space.

Dividend payout ratio (common stock)

Dividend payout ratio (common stock) is the ratio of the absolute dollar amount of dividends on our common stock (shares of common stock outstanding on the respective record dates multiplied by the related dividend per share) to funds from operations attributable to Alexandria’s common stockholders – diluted, as adjusted.

Dividend yield

Dividend yield for the quarter represents the annualized quarter dividend divided by the closing common stock price at the end of the quarter.

Fixed-charge coverage ratio

Fixed-charge coverage ratio is a non-GAAP financial measure representing the ratio of Adjusted EBITDA to fixed charges. We believe this ratio is useful to investors as a supplemental measure of our ability to satisfy fixed financing obligations and preferred stock dividends. Cash interest is equal to interest expense calculated in accordance with GAAP plus capitalized interest, less amortization of loan fees and debt premiums (discounts).

The following table reconciles interest expense, the most directly comparable financial measure calculated and presented in accordance with GAAP, to cash interest and fixed charges:

	Three Months Ended
(Dollars in thousands)	6/30/21		3/31/21		12/31/20		9/30/20		6/30/20
Adjusted EBITDA	$	370,894	$	349,720	$	332,902	$	318,070	$	313,461
Interest expense	$	35,158	$	36,467	$	37,538	$	43,318	$	45,014
Capitalized interest	43,492		39,886		37,589		32,556		30,793
Amortization of loan fees	(2,859)		(2,817)		(2,905)		(2,605)		(2,737)
Amortization of debt premiums	465		576		869		910		888
Cash interest and fixed charges	$	76,256	$	74,112	$	73,091	$	74,179	$	73,958
Fixed-charge coverage ratio:
– quarter annualized	4.9x		4.7x		4.6x		4.3x		4.2x
– trailing 12 months	4.6x		4.4x		4.4x		4.3x		4.2x
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	52
---	---		Definitions and Reconciliations (continued)
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June 30, 2021

Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders

GAAP-basis accounting for real estate assets utilizes historical cost accounting and assumes that real estate values diminish over time. In an effort to overcome the difference between real estate values and historical cost accounting for real estate assets, the Nareit Board of Governors established funds from operations as an improved measurement tool. Since its introduction, funds from operations has become a widely used non-GAAP financial measure among equity REITs. We believe that funds from operations is helpful to investors as an additional measure of the performance of an equity REIT. Moreover, we believe that funds from operations, as adjusted, allows investors to compare our performance to the performance of other real estate companies on a consistent basis, without having to account for differences recognized because of real estate acquisition and disposition decisions, financing decisions, capital structure, capital market transactions, variances resulting from the volatility of market conditions outside of our control, or other corporate activities that may not be representative of the operating performance of our properties.

The 2018 White Paper published by the Nareit Board of Governors (the “Nareit White Paper”) defines funds from operations as net income (computed in accordance with GAAP), excluding gains or losses on sales of real estate, and impairments of real estate, plus depreciation and amortization of operating real estate assets, and after adjustments for our share of consolidated and unconsolidated partnerships and real estate joint ventures. Impairments represent the write-down of assets when fair value over the recoverability period is less than the carrying value due to changes in general market conditions and do not necessarily reflect the operating performance of the properties during the corresponding period.

We compute funds from operations, as adjusted, as funds from operations calculated in accordance with the Nareit White Paper, excluding significant gains, losses, and impairments realized on non-real estate investments, unrealized gains or losses on non-real estate investments, gains or losses on early extinguishment of debt, significant termination fees, acceleration of stock compensation expense due to the resignation of an executive officer, deal costs, the income tax effect related to such items, and the amount of such items that is allocable to our unvested restricted stock awards. Neither funds from operations nor funds from operations, as adjusted, should be considered as alternatives to net income (determined in accordance with GAAP) as indications of financial performance, or to cash flows from operating activities (determined in accordance with GAAP) as measures of liquidity, nor are they indicative of the availability of funds for our cash needs, including our ability to make distributions.

The following table reconciles net income to funds from operations for the share of consolidated real estate joint ventures attributable to noncontrolling interests and our share of unconsolidated real estate joint ventures:

(In thousands)	Noncontrolling Interest Share of Consolidated Real Estate JVs				Our Share of Unconsolidated <br>Real Estate JVs
	June 30, 2021				June 30, 2021
	Three Months Ended		Six Months Ended		Three Months Ended		Six Months Ended
Net income	$	19,436	$	36,848	$	2,609	$	6,146
Depreciation and amortization	16,301		31,744		4,135		7,211
Funds from operations	$	35,737	$	68,592	$	6,744	$	13,357

Initial stabilized yield (unlevered)

Initial stabilized yield is calculated as the estimated amounts of net operating income at stabilization divided by our investment in the property. Our initial stabilized yield excludes the benefit of leverage. Our cash rents related to our value-creation projects are generally expected to increase over time due to contractual annual rent escalations. Our estimates for initial stabilized yields, initial stabilized yields (cash basis), and total costs at completion represent our initial estimates at the commencement of the project. We expect to update this information upon completion of the project, or sooner if there are significant changes to the expected project yields or costs.

•Initial stabilized yield reflects rental income, including contractual rent escalations and any rent concessions over the term(s) of the lease(s), calculated on a straight-line basis.

•Initial stabilized yield (cash basis) reflects cash rents at the stabilization date after initial rental concessions, if any, have elapsed and our total cash investment in the property.

Investment-grade or publicly traded large cap tenants

Investment-grade or publicly traded large cap tenants represent tenants that are investment-grade rated or publicly traded companies with an average daily market capitalization greater than $10 billion for the twelve months ended June 30, 2021, as reported by Bloomberg Professional Services. Credit ratings from Moody’s Investors Service and S&P Global Ratings reflect credit ratings of the tenant’s parent entity, and there can be no assurance that a tenant’s parent entity will satisfy the tenant’s lease obligation upon such tenant’s default. We monitor the credit quality and related material changes of our tenants. Material changes that cause a tenant’s market capitalization to decline below $10 billion, which are not immediately reflected in the twelve-month average, may result in their exclusion from this measure.

Investments

We hold investments in publicly traded companies and privately held entities primarily

involved in the life science, agtech, and technology industries. We recognize, measure, present, and

disclose these investments as follows:

		Statements of Operations
	Balance Sheet	Gains and Losses
	Carrying Amount	Unrealized	Realized
			Difference between proceeds received upon disposition and historical cost
Publicly traded companies	Fair value	Changes in fair value
Privately held entities without readily determinable fair values that:
Report NAV	Fair value, using NAV as a practical expedient	Changes in NAV, as a practical expedient to fair value
Do not report NAV	Cost, adjusted for observable price changes and impairments	Observable price changes	Impairments to reduce costs to fair value, which result in an adjusted cost basis and the differences between proceeds received upon disposition and adjusted or historical cost
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	53
---	---		Definitions and Reconciliations (continued)
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June 30, 2021

For investments in privately held entities that do not report NAV per share, an observable

price is a price observed in an orderly transaction for an identical or similar investment of the same issuer. Observable price changes result from, among other things, equity transactions for the same issuer executed during the reporting period, including subsequent equity offerings or other reported equity transactions related to the same issuer. For these transactions to be considered observable price changes of the same issuer, we evaluate whether these transactions have similar rights and obligations, including voting rights, distribution preferences, conversion rights, and other factors, to the investments we hold.

Investments in real estate

The following table reconciles our investments in real estate as of June 30, 2021:

(In thousands)	Investments in Real Estate
Gross investments in real estate	$	25,117,311
Less: accumulated depreciation	(3,457,337)
Net investments in real estate – North America	21,659,974
Net investments in real estate – Asia	32,411
Investments in real estate	$	21,692,385	Space Intentionally Blank
---

The square footage presented in the table below includes RSF of buildings in operation as of June 30, 2021, primarily representing lease expirations at recently acquired properties that also have inherent future development or redevelopment opportunities, for which we have the intent to demolish or redevelop the existing property upon expiration of the existing in-place leases and commencement of future construction:

	Dev/<br>Redev		RSF of Lease Expirations Targeted for<br>Development and Redevelopment
Property/Submarket		2021		2022		Thereafter			Total
Near-term projects:
50 and 60 Sylvan Road/Route 128	Redev		202,428		—		—			202,428
651 Gateway Boulevard/South San Francisco	Redev		—		198,089		101,921	(1)		300,010
11255 and 11355 North Torrey Pines Road/<br> Torrey Pines	Dev		—		139,135		—			139,135
10931 and 10933 North Torrey Pines Road/<br> Torrey Pines	Dev		—		92,450		—			92,450
10277 Scripps Ranch Boulevard/Other	Redev		32,774		—		—			32,774
Other/Seattle	Redev		—		51,255		—			51,255
			235,202		480,929		101,921			818,052
Intermediate-term projects:
3825 Fabian Way/Greater Stanford	Redev		—		250,000		—			250,000
3450 and 3460 Hillview Avenue/Greater Stanford	Redev		—		42,340		34,611			76,951
9393 Towne Centre Drive/University Town Center	Dev		42,222		—		—			42,222
			42,222		292,340		34,611			369,173
Future projects:
550 Arsenal Street/Cambridge/Inner Suburbs	Dev		—		—		260,867			260,867
380 and 420 E Street/Seaport Innovation District	Dev		—		—		195,506			195,506
40 Sylvan Road/Route 128	Redev		—		—		312,845			312,845
3875 Fabian Way/Greater Stanford	Redev		—		—		228,000			228,000
960 Industrial Road/Greater Stanford	Dev		—		—		110,000			110,000
2475 Hanover Street/Greater Stanford	Redev		—		—		83,980			83,980
219 East 42nd Street/New York City	Dev		—		—		349,947			349,947
10975 and 10995 Torreyana Road/Torrey Pines	Dev		—		—		84,829			84,829
4161 Campus Point Court/University Town Center	Dev		—		—		159,884			159,884
10260 Campus Point Drive/University Town Center	Dev		—		—		109,164			109,164
Sequence District by Alexandria/Sorrento Mesa	Dev/Redev		—		—		689,938			689,938
9444 Waples Street/Sorrento Mesa	Dev		—		—		88,380			88,380
4045 and 4075 Sorrento Valley Boulevard/<br> Sorrento Valley	Dev		—		—		50,926			50,926
601 Dexter Avenue North/Lake Union	Dev		—		—		18,680			18,680
830 4th Avenue South/SoDo	Dev		—		—		42,380			42,380
			—		—		2,785,326			2,785,326
			277,424		773,269		2,921,858			3,972,551

(1) Represents vacant square footage as of June 30, 2021.

Joint venture financial information

We present components of balance sheet and operating results information related to our real estate joint ventures, which are not presented, or intended to be presented, in accordance with GAAP. We present the proportionate share of certain financial line items as follows: (i) for each real estate joint venture that we consolidate in our financial statements, which are controlled by us through contractual rights or majority voting rights, but of which we own less than 100%, we apply the noncontrolling interest economic ownership percentage to each financial item to arrive at the amount of such cumulative noncontrolling interest share of each component presented; and (ii) for each real estate joint venture that we do not control and do not consolidate, and are instead controlled jointly or by our joint venture partners through contractual rights or majority voting rights, we apply our economic ownership percentage to each financial item to arrive at our proportionate share of each component presented.

The components of balance sheet and operating results information related to our real estate joint ventures do not represent our legal claim to those items. For each entity that we do not wholly own, the joint venture agreement generally determines what equity holders can receive upon capital events, such as sales or refinancing, or in the event of a liquidation. Equity holders are normally entitled to their respective legal ownership of any residual cash from a joint venture only after all liabilities, priority distributions, and claims have been repaid or satisfied.

We believe this information can help investors estimate the balance sheet and operating results information related to our partially owned entities. Presenting this information provides a perspective not immediately available from consolidated financial statements and one that can supplement an understanding of the joint venture assets, liabilities, revenues, and expenses included in our consolidated results.

The components of balance sheet and operating results information related to our real estate joint ventures are limited as an analytical tool as the overall economic ownership interest does not represent our legal claim to each of our joint ventures’ assets, liabilities, or results of operations. In addition, joint venture financial information may include financial information related to the unconsolidated real estate joint ventures that we do not control. We believe that in order to facilitate for investors a clear understanding of our operating results and our total assets and liabilities, joint venture financial information should be examined in conjunction with our consolidated statements of operations and balance sheets. Joint venture financial information should not be considered an alternative to our consolidated financial statements, which are presented and prepared in accordance with GAAP.

Key items included in net income attributable to Alexandria’s common stockholders

We present a tabular comparison of items, whether gain or loss, that may facilitate a high-level understanding of our results and provide context for the disclosures included in this Supplemental Information, our most recent annual report on Form 10-K, and our subsequent quarterly reports on Form 10-Q. We believe such tabular presentation promotes a better understanding for investors of the corporate-level decisions made and activities performed that significantly affect comparison of our operating results from period to period. We also believe this tabular presentation will supplement for investors an understanding of our disclosures and real estate operating results. Gains or losses on sales of real estate and impairments of held for sale assets are related to corporate-level decisions to dispose of real estate. Gains or losses on early extinguishment of debt are related to corporate-level financing decisions focused on our capital structure strategy. Significant realized and unrealized gains or losses on non-real estate investments and impairments of real estate and non-real estate investments are not related to the operating performance of our real estate assets as they result from strategic, corporate-level non-real estate investment decisions and external market conditions. Impairments of non-real estate investments are not related to the operating performance of our real estate as they represent the write-down of non-real estate investments when their fair values decline below their respective carrying

values due to changes in general market or other conditions outside of our control. Significant items, whether a gain or loss, included in the tabular disclosure for current periods are described in further detail in this Supplemental Information and accompanying Earnings Press Release.

Net cash provided by operating activities after dividends

Net cash provided by operating activities after dividends includes the deduction for distributions to noncontrolling interests. For purposes of this calculation, changes in operating assets and liabilities are excluded as they represent timing differences.

Net debt and preferred stock to Adjusted EBITDA

Net debt and preferred stock to Adjusted EBITDA is a non-GAAP financial measure that we believe is useful to investors as a supplemental measure of evaluating our balance sheet leverage. Net debt and preferred stock is equal to the sum of total consolidated debt less cash, cash equivalents, and restricted cash, plus preferred stock outstanding as of the end of the period. Refer to the definition of Adjusted EBITDA and Adjusted EBITDA margin for further information on the calculation of Adjusted EBITDA.

The following table reconciles debt to net debt and preferred stock and computes the ratio to Adjusted EBITDA:

(Dollars in thousands)	6/30/21			3/31/21			12/31/20			9/30/20			6/30/20
Secured notes payable	$	227,984		$	229,406		$	230,925		$	342,363		$	344,784
Unsecured senior notes payable	8,313,025			8,311,512			7,232,370			7,230,819			6,738,486
Unsecured senior line of credit and commercial paper	299,990			—			99,991			249,989			440,000
Unamortized deferred financing costs	66,913			68,293			56,312			58,284			52,175
Cash and cash equivalents	(323,876)			(492,184)			(568,532)			(446,255)			(206,860)
Restricted cash	(33,697)			(42,219)			(29,173)			(38,788)			(34,680)
Preferred stock	—			—			—			—			—
Net debt and preferred stock	$	8,550,339		$	8,074,808		$	7,021,893		$	7,396,412		$	7,333,905
Adjusted EBITDA:
– quarter annualized	$	1,483,576		$	1,398,880		$	1,331,608		$	1,272,280		$	1,253,844
– trailing 12 months	$	1,371,586		$	1,314,153		$	1,274,187		$	1,228,440		$	1,185,347
Net debt and preferred stock to Adjusted EBITDA:
– quarter annualized	5.8		x	5.8		x	5.3		x	5.8		x	5.8		x
– trailing 12 months	6.2		x	6.1		x	5.5		x	6.0		x	6.2		x
Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2021	55
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June 30, 2021

Net operating income, net operating income (cash basis), and operating margin

The following table reconciles net income to net operating income and to net operating income (cash basis):

	Three Months Ended				Six Months Ended
(Dollars in thousands)	6/30/21		6/30/20		6/30/21		6/30/20
Net income	$	404,520	$	243,561	$	430,053	$	274,239
Equity in earnings of unconsolidated real estate joint ventures	(2,609)		(3,893)		(6,146)		(777)
General and administrative expenses	37,880		31,775		71,876		63,738
Interest expense	35,158		45,014		71,625		90,753
Depreciation and amortization	190,052		168,027		370,965		343,523
Impairment of real estate	4,926		13,218		10,055		15,221
Loss on early extinguishment of debt	—		—		67,253		—
Gain on sales of real estate	—		—		(2,779)		—
Investment income	(304,263)		(184,657)		(305,277)		(162,836)
Net operating income	365,664		313,045		707,625		623,861
Straight-line rent revenue	(27,903)		(23,367)		(55,285)		(43,964)
Amortization of acquired below-market leases	(13,267)		(13,787)		(25,379)		(29,751)
Net operating income (cash basis)	$	324,494	$	275,891	$	626,961	$	550,146
Net operating income (cash basis) – annualized	$	1,297,976	$	1,103,564	$	1,253,922	$	1,100,292
Net operating income (from above)	$	365,664	$	313,045	$	707,625	$	623,861
Total revenues	$	509,619	$	436,956	$	989,468	$	876,875
Operating margin	72%		72%		72%		71%

Net operating income is a non-GAAP financial measure calculated as net income, the most directly comparable financial measure calculated and presented in accordance with GAAP, excluding equity in the earnings of our unconsolidated real estate joint ventures, general and administrative expenses, interest expense, depreciation and amortization, impairments of real estate, gains or losses on early extinguishment of debt, gains or losses on sales of real estate, and investment income or loss. We believe net operating income provides useful information to investors regarding our financial condition and results of operations because it primarily reflects those income and expense items that are incurred at the property level. Therefore, we believe net operating income is a useful measure for investors to evaluate the operating performance of our consolidated real estate assets. Net operating income on a cash basis is net operating income adjusted to exclude the effect of straight-line rent and amortization of acquired above- and below-market lease revenue adjustments required by GAAP. We believe that net operating income on a cash basis is helpful to investors as an additional measure of operating performance because it eliminates straight-line rent revenue and the amortization of acquired above- and below-market leases.

Furthermore, we believe net operating income is useful to investors as a performance measure of our consolidated properties because, when compared across periods, net operating income reflects trends in occupancy rates, rental rates, and operating costs, which provide a perspective not immediately apparent from net income or loss. Net operating income can be used to measure the initial stabilized yields of our properties by calculating net operating income generated by a property divided by our investment in the property. Net operating income excludes certain components from net income in order to provide results that are more closely related to the results of operations of our properties. For example, interest expense is not necessarily linked to the operating performance of a real estate asset and is often incurred at the corporate level rather than at the property level. In addition, depreciation and amortization, because of historical cost accounting and useful life estimates, may distort comparability of operating performance at the property level. Impairments of real estate have been excluded in deriving net operating income because we do not consider impairments of real estate to be property-level operating expenses. Impairments of real estate relate to changes in the values of our assets and do not reflect the current operating performance with respect to related revenues or expenses. Our impairments of real estate represent the write-down in the value of the assets to the estimated fair value less cost to sell. These impairments result from investing decisions or a deterioration in market conditions. We also exclude realized and unrealized investment gain or loss, which results from investment decisions that occur at the corporate level related to non-real estate investments in publicly traded companies and certain privately held entities. Therefore, we do not consider these activities to be an indication of operating performance of our real estate assets at the property level. Our calculation of net operating income also excludes charges incurred from changes in certain financing decisions, such as losses on early extinguishment of debt, as these charges often relate to corporate strategy. Property operating expenses included in determining net operating income primarily consist of costs that are related to our operating properties, such as utilities, repairs, and maintenance; rental expense related to ground leases; contracted services, such as janitorial, engineering, and landscaping; property taxes and insurance; and property-level salaries. General and administrative expenses consist primarily of accounting and corporate compensation, corporate insurance, professional fees, office rent, and office supplies that are incurred as part of corporate office management. We calculate operating margin as net operating income divided by total revenues.

We believe that in order to facilitate for investors a clear understanding of our operating results, net operating income should be examined in conjunction with net income or loss as presented in our consolidated statements of operations. Net operating income should not be considered as an alternative to net income or loss as an indication of our performance, nor as an alternative to cash flows as a measure of our liquidity or our ability to make distributions.

Operating statistics

We present certain operating statistics related to our properties, including number of properties, RSF, occupancy percentage, leasing activity, and contractual lease expirations as of the end of the period. We believe these measures are useful to investors because they facilitate an understanding of certain trends for our properties. We compute the number of properties, RSF, occupancy percentage, leasing activity, and contractual lease expirations at 100% for all properties in which we have an investment, including properties owned by our consolidated and unconsolidated real estate joint ventures. For operating metrics based on annual rental revenue, refer to our discussion of annual rental revenue herein.

Same property comparisons

As a result of changes within our total property portfolio during the comparative periods presented, including changes from assets acquired or sold, properties placed into development or redevelopment, and development or redevelopment properties recently placed into service, the consolidated total income from rentals, as well as rental operating expenses in our operating results, can show significant changes from period to period. In order to supplement an evaluation of our results of operations over a given quarterly or annual period, we analyze the operating performance for all consolidated properties that were fully operating for the entirety of the comparative periods presented, referred to as same properties. We separately present quarterly and year-to-date same property results to align with the interim financial information required by the SEC in our management’s discussion and analysis of our financial condition and results of operations. These same properties are analyzed separately from properties acquired subsequent to the first day in the earliest comparable quarterly or year-to-date period presented, properties that underwent development or redevelopment at any time during the comparative periods, unconsolidated real estate joint ventures, properties classified as held for sale, and corporate entities (legal entities performing general and administrative functions), which are excluded from same property results. Additionally, termination fees, if any, are excluded from the results of same properties.

Space Intentionally Blank

The following table reconciles the number of same properties to total properties for the six months ended June 30, 2021:

Development – under construction	Properties			Acquisitions after January 1, 2020				Properties
9950 Medical Center Drive	1			3181 Porter Drive				1
Alexandria Center® for Life Science – San Carlos	2			275 Grove Street				1
		601, 611, and 651 Gateway Boulevard			3
3115 Merryfield Row	1			3330, 3412, 3450, and 3460 Hillview Avenue				4
Alexandria Center® for Life Science – South San Francisco	1
		9605, 9609, 9613, and 9615 Medical Center Drive			4
Alexandria Center® for AgTech	2
Alexandria Center® for Advanced Technologies	2			9808 and 9868 Scranton Road				2
			Alexandria Center® for Life Science – Durham
201 Brookline Avenue	1						13
SD Tech by Alexandria	1			Reservoir Woods				3
	11			One Upland Road				1
Development – placed into				830 4th Avenue South				1
service after January 1, 2020	Properties			11255 and 11355 North Torrey Pines Road				2
9804 Medical Center Drive	1
1165 Eastlake Avenue East	1			Sequence District by Alexandria				7
	2			380 and 420 E Street				2
Redevelopment – under construction	Properties			Alexandria Center® for Life Science – Fenway				1
5505 Morehouse Drive	1
Alexandria Center® for Life Science – Long Island City	1			550 Arsenal Street				1
			1501-1599 Industrial Road			6
3160 Porter Drive	1			One Investors Way				1
The Arsenal on the Charles	11			2475 Hanover Street				1
700 Quince Orchard Road	1			10975 and 10995 Torreyana Road				1
Alexandria Center® for Life Science – Durham	3			9444 Waples Street				1
			Other			22
840 Winter Street	1							78
20400 Century Boulevard	1			Unconsolidated real estate JVs				5
10277 Scripps Ranch Boulevard	1			Properties held for sale				4
9601 and 9603 Medical Center Drive	2
Other	6			Total properties excluded from same properties				131
	29
Redevelopment – placed into				Same properties				250
service after January 1, 2020	Properties			Total properties in North America as of June 30, 2021				381
9877 Waples Street	1
Other	1
	2

Stabilized occupancy date

The stabilized occupancy date represents the estimated date on which the project is expected to reach occupancy of 95% or greater.

Tenant recoveries

Tenant recoveries represent revenues comprising reimbursement of real estate taxes, insurance, utilities, repairs and maintenance, common area expenses, and other operating expenses and earned in the period during which the applicable expenses are incurred and the tenant’s obligation to reimburse us arises.

We classify rental revenues and tenant recoveries generated through the leasing of real estate assets within revenue in income from rentals in our consolidated statements of operations. We provide investors with a separate presentation of rental revenues and tenant recoveries in “Same Property Performance” of this Supplemental Information because we believe it promotes investors’ understanding of our operating results. We believe that the presentation of tenant recoveries is useful to investors as a supplemental measure of our ability to recover operating expenses under our triple net leases, including recoveries of utilities, repairs and maintenance, insurance, property taxes, common area expenses, and other operating expenses, and of our ability to mitigate the effect to net income for any significant variability to components of our operating expenses.

The following table reconciles income from rentals to tenant recoveries:

	Three Months Ended										Six Months Ended
(In thousands)	6/30/21		3/31/21		12/31/20		9/30/20		6/30/20		6/30/21		6/30/20
Income from rentals	$	508,371	$	478,695	$	461,335	$	543,412	$	435,856	$	987,066	$	873,461
Rental revenues	(396,804)		(370,233)		(353,950)		(438,393)		(341,555)		(767,037)		(679,497)
Tenant recoveries	$	111,567	$	108,462	$	107,385	$	105,019	$	94,301	$	220,029	$	193,964

Total equity capitalization

Total equity capitalization is equal to the outstanding shares of common stock multiplied by the closing price on the last trading day at the end of each period presented.

Total market capitalization

Total market capitalization is equal to the sum of total equity capitalization and total debt.

Unencumbered net operating income as a percentage of total net operating income

Unencumbered net operating income as a percentage of total net operating income is a non-GAAP financial measure that we believe is useful to investors as a performance measure of the results of operations of our unencumbered real estate assets as it reflects those income and expense items that are incurred at the unencumbered property level. Unencumbered net operating income is derived from assets classified in continuing operations, which are not subject to any mortgage, deed of trust, lien, or other security interest, as of the period for which income is presented.

The following table summarizes unencumbered net operating income as a percentage of total net operating income:

	Three Months Ended
(Dollars in thousands)	6/30/21		3/31/21		12/31/20		9/30/20		6/30/20
Unencumbered net operating income	$	353,104	$	330,160	$	315,586	$	388,575	$	296,358
Encumbered net operating income	12,560		11,801		11,367		16,024		16,687
Total net operating income	$	365,664	$	341,961	$	326,953	$	404,599	$	313,045
Unencumbered net operating income as a percentage of total net operating income	97%		97%		97%		96%		95%

Weighted-average interest rate for capitalization of interest

The weighted-average interest rate required for calculating capitalization of interest pursuant to GAAP represents a weighted-average rate based on the rates applicable to borrowings outstanding during the period, including expense/income related to interest rate hedge agreements, amortization of loan fees, amortization of debt premiums (discounts), and other bank fees. A separate calculation is performed to determine our weighted-average interest rate for capitalization for each month. The rate will vary each month due to changes in variable interest rates, outstanding debt balances, the proportion of variable-rate debt to fixed-rate debt, the amount and terms of interest rate hedge agreements, and the amount of loan fee and premium (discount) amortization.

The following table presents the weighted-average interest rate for capitalization of interest:

	Three Months Ended
	6/30/21	3/31/21	12/31/20	9/30/20	6/30/20
Weighted-average interest rate for capitalization of interest	3.47%	3.44%	3.66%	3.64%	4.03%

Weighted-average shares of common stock outstanding – diluted

From time to time, we enter into capital market transactions, including forward equity sales agreements (“Forward Agreements”), to fund acquisitions, to fund construction of our highly leased development and redevelopment projects, and for general working capital purposes. We are required to consider the potential dilutive effect of our forward equity sales agreements under the treasury stock method while the forward equity sales agreements are outstanding. As of June 30, 2021, we had Forward Agreements outstanding to sell an aggregate of 4.6 million shares of common stock.

The weighted-average shares of common stock outstanding used in calculating EPS – diluted, FFO per share – diluted, and FFO per share – diluted, as adjusted, during each period are calculated as follows:

	Three Months Ended					Six Months Ended
(In thousands)	6/30/21	3/31/21	12/31/20	9/30/20	6/30/20	6/30/21	6/30/20
Weighted-average of common stock outstanding – basic	145,825	137,319	133,688	124,901	124,333	141,596	122,883
Forward Agreements	233	369	139	927	115	300	234
Weighted-average of common stock outstanding – diluted	146,058	137,688	133,827	125,828	124,448	141,896	123,117
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