TWO SIGMA INVESTMENTS, LP

Position in COGT — Cogent Biosciences, Inc.

CIK 1179392 NEW YORK, NY

Position in COGT

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$1,456,551

-$586,883 QoQ

Shares Held

37,637

-29.1% QoQ

Ownership

0.022%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#175

of 321 holders

Holding Since

Sep 2022

11 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,273,657,992 across 342 Biotechnology names. COGT ranks #186 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$1,456,551	37,637	-29.1%	Shares	Sole	2026-08-14
2026-03-31	$2,043,434	53,090	+321.3%	Shares	Sole	2026-05-15
2025-12-31	$447,552	12,600	-86.7%	Shares	Sole	2026-02-17
2025-03-31	$567,881	94,805	-7.0%	Shares	Sole	2025-05-15
2024-12-31	$795,522	101,990	-4.3%	Shares	Sole	2025-02-14
2024-09-30	$1,151,528	106,623	-28.6%	Shares	Sole	2024-11-14
2024-06-30	$1,259,450	149,401	+6.2%	Shares	Sole	2024-08-14
2024-03-31	$945,571	140,710	+732.1%	Shares	Sole	2024-05-15
2023-03-31	$182,458	16,910	-82.4%	Shares	Sole	2023-05-15
2022-12-31	$1,109,644	95,990	-35.7%	Shares	Sole	2023-02-14
2022-09-30	$2,228,361	149,354	—	Shares	Sole	2022-11-14
No filing history on record for this holder in this stock.