TWO SIGMA INVESTMENTS, LP

Position in DYN — Dyne Therapeutics, Inc.

CIK 1179392 NEW YORK, NY

Position in DYN

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$314,893

-$5,301,651 QoQ

Shares Held

14,178

-91.1% QoQ

Ownership

0.008%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#159

of 245 holders

Holding Since

Mar 2021

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,273,664,878 across 342 Biotechnology names. DYN ranks #267 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$314,893	14,178	-91.1%	Shares	Sole	2026-08-14
2024-06-30	$5,616,544	159,154	+1685.8%	Shares	Sole	2024-08-14
2024-03-31	$253,011	8,912	-63.5%	Shares	Sole	2024-05-15
2023-09-30	$218,624	24,400	-24.9%	Shares	Sole	2023-11-14
2023-06-30	$365,625	32,500	-79.6%	Shares	Sole	2023-08-14
2023-03-31	$1,831,530	158,987	+2.3%	Shares	Sole	2023-05-15
2022-12-31	$1,800,494	155,349	+812.5%	Shares	Sole	2023-02-14
2022-09-30	$216,204	17,024	-36.3%	Shares	Sole	2022-11-14
2022-03-31	$257,600	26,722	-79.1%	Shares	Sole	2022-05-16
2021-12-31	$1,518,697	127,729	+12.8%	Shares	Sole	2022-02-14
2021-09-30	$1,838,432	113,204	+335.4%	Shares	Sole	2021-11-15
2021-03-31	$403,780	26,000	—	Shares	Sole	2021-05-17
No filing history on record for this holder in this stock.