TWO SIGMA INVESTMENTS, LP
Position in HRMY — Harmony Biosciences Holdings, Inc.
CIK 1179392
NEW YORK, NY
Position in HRMY
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$34,922,141
+$14,378,403 QoQ
Shares Held
959,136
+30.8% QoQ
Ownership
1.65%
of shares outstanding
% of Portfolio
0.03%
of 13F equity value
Holder Rank
#13
of 328 holders
Holding Since
Dec 2020
20 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in HRMY Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,273,657,992 across 342 Biotechnology names. HRMY ranks #42 (0.5% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in HRMY
Export CSV
20 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $34,922,141 | 959,136 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $20,543,738 | 733,443 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $7,744,181 | 206,953 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $6,208,909 | 225,287 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $7,548,860 | 238,888 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $11,477,334 | 345,807 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $9,483,189 | 275,594 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $5,719,960 | 142,999 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $2,816,641 | 93,359 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $2,366,819 | 70,483 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $323,129 | 10,004 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $4,091,039 | 124,841 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $12,601,292 | 358,093 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $7,474,335 | 228,923 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $10,102,364 | 183,346 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $6,060,510 | 136,837 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $1,706,950 | 35,000 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $11,092,200 | 228,000 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $490,743 | 11,509 | Shares | Sole | 2022-02-14 | |
| 2020-12-31 | $285,151 | 7,888 | Shares | Sole | 2021-02-16 | |
| No filing history on record for this holder in this stock. | ||||||