TWO SIGMA INVESTMENTS, LP

Position in HUMA — Humacyte, Inc.

CIK 1179392 NEW YORK, NY

Position in HUMA

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$23,047

-$84,717 QoQ

Shares Held

29,548

-83.4% QoQ

Ownership

0.011%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#83

of 163 holders

Holding Since

Dec 2021

14 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. HUMA ranks #332 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

14 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$23,047	29,548	-83.4%	Shares	Sole	2026-08-14
2026-03-31	$107,764	177,536	-88.1%	Shares	Sole	2026-05-15
2025-12-31	$1,433,299	1,491,467	+9.1%	Shares	Sole	2026-02-17
2025-09-30	$2,377,856	1,366,584	-11.1%	Shares	Sole	2025-11-14
2025-06-30	$3,213,126	1,537,381	+162.2%	Shares	Sole	2025-08-14
2025-03-31	$999,881	586,441	-36.2%	Shares	Sole	2025-05-15
2024-12-31	$4,641,439	919,097	-14.0%	Shares	Sole	2025-02-14
2024-09-30	$5,811,220	1,068,239	-6.5%	Shares	Sole	2024-11-14
2024-06-30	$5,481,801	1,142,042	+4356.2%	Shares	Sole	2024-08-14
2024-03-31	$79,703	25,628	-92.3%	Shares	Sole	2024-05-15
2023-12-31	$944,799	332,676	+182.9%	Shares	Sole	2024-02-14
2023-09-30	$344,573	117,602	+378.7%	Shares	Sole	2023-11-14
2022-12-31	$51,836	24,567	-20.9%	Shares	Sole	2023-02-14
2021-12-31	$225,192	31,061	—	Shares	Sole	2022-02-14
No filing history on record for this holder in this stock.