Position in IPSC
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$6,612,581
+$1,253,150 QoQ
Shares Held
2,699,013
+13.8% QoQ
Ownership
1.49%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#19
of 98 holders
Holding Since
Dec 2022
10 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in IPSC Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,273,664,878 across 342 Biotechnology names. IPSC ranks #102 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in IPSC
Export CSV
10 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $6,612,581 | 2,699,013 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $5,359,431 | 2,371,430 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $1,488,436 | 1,495,916 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $453,900 | 911,446 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $320,052 | 572,544 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $40,938 | 86,006 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $67,464 | 66,797 | Shares | Sole | 2025-02-14 | |
| 2023-06-30 | $50,130 | 15,864 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $129,146 | 37,218 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $183,972 | 35,862 | Shares | Sole | 2023-02-14 | |
| No filing history on record for this holder in this stock. | ||||||