Ligand Pharmaceuticals Incorporated reported Q3 2026 royalties of $70.3 million, up 51%, while total revenue and income fell 32% to $78.7 million. Its July 14, 2026 XOMA acquisition expanded the portfolio to over 200 commercial, clinical and preclinical royalty assets.
LGND · Ligand Pharmaceuticals Inc
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Ligand reported royalty revenue of $70.3 million, up 51% year-over-year, and raised adjusted diluted EPS guidance to $9.50 to $9.75 per share. The $730 million Zoma acquisition closed, and up to seven pivotal readouts are expected through 2027.
Ligand Pharmaceuticals reported third-quarter 2026 royalty revenue up 51% year-over-year to $70.3 million and raised 2026 adjusted diluted EPS guidance to $9.50 to $9.75 from $9.00 to $9.50, while reaffirming revenue guidance of $270 million to $310 million.
Ligand Pharmaceuticals Incorporated entered a financing agreement with AvenCell Therapeutics, Inc. for up to $47 million, including up to $41 million for royalties on AvenCell assets and up to $6 million in Series C financing.
Ligand acquired royalty and milestone rights to Santen’s Ryjunea from Sydnexis for $23 million upfront, including a tiered low-double-digit to high-teens royalty on net sales in EMEA and certain milestone payments.
Metrics snapshot
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Quarterly results
* Q4 derived as the full year minus Q1 to Q3.
AI Brief
Q3 FY26 earnings call · Oct 29, 2026TL;DR. Third-quarter royalty revenue grew 51% year-over-year to $70.3 million, like-for-like total revenues and income increased 26%, and nine-month adjusted diluted EPS increased 10%, while Ligand raised 2026 adjusted diluted EPS guidance to $9.50–$9.75 and reaffirmed revenue guidance. The XOMA acquisition more than doubled Ligand’s portfolio, which now exceeds 200 assets, and left approximately $750 million of deployable capital; however, quarterly adjusted EPS and GAAP earnings declined as higher G&A, investment losses, lower liquidity, and revenue-timing uncertainty pressured results.
- + Ligand raised full-year 2026 adjusted diluted EPS guidance to $9.50–$9.75 from $9.00–$9.50 while reaffirming revenue guidance.
- + Filspari became Ligand’s largest royalty asset at an estimated $16.8 million for the quarter, up 85% from a year ago.
- + Palvella’s Qtorin rapamycin NDA received FDA Priority Review with a February 28, 2027 PDUFA date and a potential first-half 2027 launch.
- − Third-quarter G&A expense increased to $72.6 million from $28.4 million, primarily due to XOMA transaction, integration, share-based compensation, and expanded staffing costs.
- − Cash, cash equivalents, and short-term investments declined to $447.4 million from $733.5 million at December 31, 2025, primarily because of the XOMA acquisition.
- − Customer-order and milestone timing creates uncertainty and can shift revenue between quarters.
AI-generated from the earnings call and 8-K · may contain errors · not investment advice
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Key metrics
the company's own KPIs, from written earnings releases and filings| Metric | Latest | Period | YoY |
|---|---|---|---|
| Adjusted net income non-GAAP | $85.4M | six months ended June 30, 2026 | — |
Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period
Versus peers
Biotechnology — same industry group| Company | Mkt cap | YTD | Rev growth Y/Y | P/E | Short % shares |
|---|---|---|---|---|---|
|
LGND
this stock
Ligand Pharmaceuticals Inc
|
$6.18B | +63.3% | +29.5% | 121.6 | 12.3% |
|
VRTX
Vertex Pharmaceuticals Inc
|
$136.56B | +18.8% | +46.2% | 34.7 | 1.9% |
|
REGN
Regeneron Pharmaceuticals, Inc.
|
$98.84B | +23.8% | +20.8% | 21.1 | 2.1% |
|
MRNA
Moderna, Inc.
|
$90.38B | +657.4% | +4.3% | — | 8.2% |
|
CSLLY
Csl Ltd
|
$66.05B | — | — | — | 0.0% |
Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding
At a glance
key data from every section- Filed
- Oct 30, 2026
- This year
- 25
Ligand Pharmaceuticals Incorporated reported Q3 2026 royalties of $70.3 million, up 51%, while total revenue and income fell 32% to $78.7 million. Its July 14, 2026 XOMA acquisition expanded the portfolio to over 200 commercial, clinical and preclinical royalty assets.
ViewPerformance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| LGND | +0.9% | +4.5% | +31.2% | -4.3% | +63.3% |
| SPY | +2.6% | -1.2% | +0.5% | -0.2% | +10.6% |
| vs SPY | -1.7% | +5.6% | +30.7% | -4.2% | +52.7% |
Capital returns
Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.