Position in MCRB
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$166,702
-$216,443 QoQ
Shares Held
18,794
-27.0% QoQ
Ownership
0.189%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
16 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in MCRB Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,273,657,992 across 342 Biotechnology names.
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in MCRB
Export CSV
16 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $166,702 | 18,794 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $383,145 | 25,749 | Shares | Sole | 2026-02-17 | |
| 2025-03-31 | $22,629 | 32,328 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $20,286 | 24,412 | Shares | Sole | 2025-02-14 | |
| 2023-12-31 | $489,423 | 349,588 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $28,629 | 12,029 | Shares | Sole | 2023-11-14 | |
| 2022-06-30 | $1,152,672 | 336,056 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $912,442 | 128,152 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $554,353 | 66,549 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $6,955,935 | 999,416 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $3,796,967 | 159,202 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $4,321,861 | 209,901 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $3,442,495 | 140,510 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $773,655 | 27,328 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $754,217 | 158,449 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $161,546 | 45,251 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||