Position in REPL
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$1,844,173
-$793,172 QoQ
Shares Held
166,592
-51.7% QoQ
Ownership
0.177%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#50
of 199 holders
Holding Since
Jun 2020
23 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in REPL Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. REPL ranks #169 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in REPL
Export CSV
23 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $1,844,173 | 166,592 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $2,637,345 | 344,751 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $4,316,399 | 444,074 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $659,920 | 157,499 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $208,291 | 22,421 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $432,929 | 44,403 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $2,574,416 | 212,586 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $1,964,470 | 179,240 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $1,863,180 | 207,020 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $2,523,230 | 308,841 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $962,554 | 114,182 | Shares | Sole | 2024-02-14 | |
| 2023-06-30 | $4,228,617 | 182,111 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $4,501,957 | 254,924 | Shares | Sole | 2023-05-15 | |
| 2022-09-30 | $1,461,629 | 84,634 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $1,052,418 | 60,207 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $3,715,088 | 218,792 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $2,620,786 | 96,708 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $3,146,463 | 106,156 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $6,027,636 | 156,888 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $11,248,884 | 368,695 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $12,548,755 | 328,932 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $1,469,481 | 63,835 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $318,750 | 12,827 | Shares | Sole | 2020-08-14 | |
| No filing history on record for this holder in this stock. | ||||||