Position in RPRX
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$163,733,539
+$55,727,885 QoQ
Shares Held
2,920,163
+29.7% QoQ
Ownership
0.508%
of shares outstanding
% of Portfolio
0.13%
of 13F equity value
Holder Rank
#25
of 646 holders
Holding Since
Dec 2021
19 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in RPRX Over Time
Shares Held
Position Value (USD)
Derivatives in RPRX
reported options exposure · as of Dec 31, 2021CallValue
$0
CallShares
0
PutValue
$290,905
PutShares
7,300
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. RPRX ranks #10 (2.2% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in RPRX
Export CSV
20 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $163,733,539 | 2,920,163 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $108,005,654 | 2,251,525 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $26,323,422 | 681,248 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $41,782,492 | 1,184,311 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,949,295 | 54,102 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $50,212,970 | 1,613,009 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $61,744,480 | 2,420,403 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $68,725,915 | 2,429,336 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $54,257,329 | 2,057,540 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $39,592,123 | 1,303,659 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $59,305,518 | 2,111,268 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $59,890,245 | 2,206,715 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $34,788,335 | 1,131,696 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $6,279,452 | 174,284 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $17,393,107 | 440,109 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $31,796,041 | 791,340 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $19,798,611 | 470,947 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $7,286,571 | 187,027 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $6,115,978 | 153,475 | Shares | Sole | 2022-02-14 | |
| 2021-12-31 | $290,905 | 7,300 | Put | Sole | 2022-02-14 | |
| No filing history on record for this holder in this stock. | ||||||