Position in RPRX
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$108,005,654
+$81,682,232 QoQ
Shares Held
2,251,525
+230.5% QoQ
Ownership
0.391%
of shares outstanding
% of Portfolio
0.10%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2021
18 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in RPRX Over Time
Shares Held
Position Value (USD)
Derivatives in RPRX
reported options exposure · as of Dec 31, 2021CallValue
$0
CallShares
0
PutValue
$290,905
PutShares
7,300
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. RPRX ranks #9 (2.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in RPRX
Export CSV
19 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $108,005,654 | 2,251,525 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $26,323,422 | 681,248 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $41,782,492 | 1,184,311 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,949,295 | 54,102 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $50,212,970 | 1,613,009 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $61,744,480 | 2,420,403 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $68,725,915 | 2,429,336 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $54,257,329 | 2,057,540 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $39,592,123 | 1,303,659 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $59,305,518 | 2,111,268 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $59,890,245 | 2,206,715 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $34,788,335 | 1,131,696 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $6,279,452 | 174,284 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $17,393,107 | 440,109 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $31,796,041 | 791,340 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $19,798,611 | 470,947 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $7,286,571 | 187,027 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $6,115,978 | 153,475 | Shares | Sole | 2022-02-14 | |
| 2021-12-31 | $290,905 | 7,300 | Put | Sole | 2022-02-14 | |
| No filing history on record for this holder in this stock. | ||||||