TWO SIGMA INVESTMENTS, LP

Position in SGMT — Sagimet Biosciences Inc.

CIK 1179392 NEW YORK, NY

Position in SGMT

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$633,102

+$423,413 QoQ

Shares Held

81,902

+104.1% QoQ

Ownership

0.132%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#51

of 122 holders

Holding Since

Dec 2023

11 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. SGMT ranks #233 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$633,102	81,902	+104.1%	Shares	Sole	2026-08-14
2026-03-31	$209,689	40,132	-5.6%	Shares	Sole	2026-05-15
2025-12-31	$251,789	42,532	-16.9%	Shares	Sole	2026-02-17
2025-09-30	$351,170	51,191	+292.4%	Shares	Sole	2025-11-14
2025-06-30	$99,402	13,045	-73.8%	Shares	Sole	2025-08-14
2025-03-31	$162,507	49,849	-1.2%	Shares	Sole	2025-05-15
2024-12-31	$226,948	50,433	-72.5%	Shares	Sole	2025-02-14
2024-09-30	$508,677	183,638	+148.2%	Shares	Sole	2024-11-14
2024-06-30	$253,025	73,984	-1.6%	Shares	Sole	2024-08-14
2024-03-31	$407,697	75,221	+71.3%	Shares	Sole	2024-05-15
2023-12-31	$237,938	43,900	—	Shares	Sole	2024-02-14
No filing history on record for this holder in this stock.