SLP · Simulations Plus, Inc.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting person.

These shares were sold in multiple transactions at prices ranging from $18.34 to $18.39, inclusive.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

These shares were sold in multiple transactions at prices ranging from $18.36 to $18.49, inclusive.

The number of shares reflects a revision to correct the inadvertent inclusion of 46,492 shares of the issuer's common stock from previously reported holdings of the reporting persons.

Fully Vested

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in a single transaction at $18.20.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in a single transaction at $16.51.

Fully Vested

The sale reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting person.

These shares were sold in a single transaction at $16.50.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

These shares were sold in multiple transactions at prices ranging from $16.61 to $17.75, inclusive.

Fully Vested

The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting person.

These shares were sold in a single transaction at $16.53.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in a single transaction at $14.98.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnote (3) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

These shares were sold in multiple transactions at prices ranging from $15.00 to $15.24, inclusive.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting person.

There shares were sold in a single transaction at $13.37.

Fully vested.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Fully vested.

The reporting person(s) made a bona fide gift of 9,095 shares of common stock to the Auburn University Foundation.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

There shares were sold in a single transaction at $16.91.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

The stock options shall vest in four equal installments over a four year period, with one fourth of the stock options vesting on each anniversary of the date of grant.

The stock options shall vest in four equal installments over a four year period, with one fourth of the stock options vesting on each anniversary of the date of grant.

The stock options shall vest in four equal installments over a four year period, with one fourth of the stock options vesting on each anniversary of the date of grant.

The stock options shall vest 40% on the first anniversary date and continuing to vest on the 2nd and 3rd anniversary dates thereafter at 30%.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnote (3) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnote.

These shares were sold in multiple transactions at prices ranging from $15.02 to $15.77, inclusive.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting person.

These shares were sold in a single transaction at $14.10.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting person.

These shares were sold in a single transaction at $12.93.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

Stock granted as independent director compensation, issued under the issuer's 2021 Equity Incentive Plan.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3) and (4) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

These shares were sold in multiple transactions at prices ranging from $18.35 to $18.91, inclusive.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3) and (4) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

These shares were sold in multiple transactions at prices ranging from $17.35 to $18.33, inclusive.

The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3), (4), (5), (6) and (7) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

These shares were sold in multiple transactions at prices ranging from $30.34 to $31.04, inclusive.