TWO SIGMA INVESTMENTS, LP

Position in STTK — Shattuck Labs, Inc.

CIK 1179392 NEW YORK, NY

Position in STTK

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$1,290,472

-$741,485 QoQ

Shares Held

185,947

-41.2% QoQ

Ownership

0.185%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#39

of 100 holders

Holding Since

Dec 2021

14 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. STTK ranks #193 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

14 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$1,290,472	185,947	-41.2%	Shares	Sole	2026-08-14
2026-03-31	$2,031,957	316,012	-27.8%	Shares	Sole	2026-05-15
2025-12-31	$1,597,710	437,729	+7.1%	Shares	Sole	2026-02-17
2025-09-30	$976,549	408,598	+431.1%	Shares	Sole	2025-11-14
2025-06-30	$60,931	76,934	-9.7%	Shares	Sole	2025-08-14
2025-03-31	$80,976	85,238	-34.8%	Shares	Sole	2025-05-15
2024-12-31	$158,121	130,679	-31.3%	Shares	Sole	2025-02-14
2024-09-30	$664,318	190,349	-17.0%	Shares	Sole	2024-11-14
2024-06-30	$884,897	229,248	+84.6%	Shares	Sole	2024-08-14
2024-03-31	$1,110,160	124,179	+299.3%	Shares	Sole	2024-05-15
2022-09-30	$83,978	31,103	-35.4%	Shares	Sole	2022-11-14
2022-06-30	$195,521	48,158	-72.0%	Shares	Sole	2022-08-15
2022-03-31	$733,184	172,109	+19.9%	Shares	Sole	2022-05-16
2021-12-31	$1,221,567	143,545	—	Shares	Sole	2022-02-14
No filing history on record for this holder in this stock.