Position in TBPH
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$20,425,406
+$10,371,756 QoQ
Shares Held
1,258,497
+134.2% QoQ
Ownership
2.44%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Jun 2020
15 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in TBPH Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,458,107,972 across 316 Biotechnology names. TBPH ranks #45 (0.4% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in TBPH
Export CSV
15 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $20,425,406 | 1,258,497 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $10,053,650 | 537,341 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $3,376,571 | 231,272 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $196,245 | 17,792 | Shares | Sole | 2025-08-14 | |
| 2024-06-30 | $419,955 | 49,523 | Shares | Sole | 2024-08-14 | |
| 2023-12-31 | $437,674 | 38,939 | Shares | Sole | 2024-02-14 | |
| 2023-06-30 | $600,900 | 58,058 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $3,872,006 | 356,867 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $10,802,907 | 962,826 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $6,620,101 | 652,870 | Shares | Sole | 2022-11-14 | |
| 2022-03-31 | $1,426,734 | 149,240 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $387,479 | 35,066 | Shares | Sole | 2022-02-14 | |
| 2021-03-31 | $836,034 | 40,962 | Shares | Sole | 2021-05-17 | |
| 2020-09-30 | $584,288 | 39,519 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $3,611,329 | 172,050 | Shares | Sole | 2020-08-14 | |
| No filing history on record for this holder in this stock. | ||||||