TWO SIGMA INVESTMENTS, LP

Position in VSTM — Verastem, Inc.

CIK 1179392 NEW YORK, NY

Position in VSTM

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$3,535,153

-$146,453 QoQ

Shares Held

667,010

+39.9% QoQ

Ownership

0.759%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Jun 2023

12 quarters on record

Voting authority Sole 97.40378704966942.ToString("F0")% Shared 0.ToString("F0")% None 2.5962129503305795.ToString("F0")%

Healthcare · as of Mar 31, 2026

TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. VSTM ranks #121 (0.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,992,577	$659,283,951
2	REGN	Regeneron Pharmaceuticals, Inc.	812,236	$627,566,023
3	MRNA	Moderna, Inc.	9,086,404	$461,589,323
4	IONS	Ionis Pharmaceuticals Inc	5,857,629	$439,849,361
5	BBIO	BridgeBio Pharma, Inc.	3,120,631	$231,738,058
6	VRTX	Vertex Pharmaceuticals Inc / Ma	378,146	$168,857,314
7	RVMD	Revolution Medicines, Inc.	1,558,807	$151,593,980
8	VKTX	Viking Therapeutics, Inc.	4,432,142	$144,221,900

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$3,535,153	667,010	+39.9%	Shares	Sole	2026-05-15
2025-12-31	$3,681,606	476,892	+12.4%	Shares	Sole	2026-02-17
2025-09-30	$3,746,145	424,252	-27.7%	Shares	Sole	2025-11-14
2025-06-30	$2,436,137	587,021	+472.5%	Shares	Sole	2025-08-14
2025-03-31	$618,340	102,544	+25.9%	Shares	Sole	2025-05-15
2024-12-31	$421,137	81,458	-19.0%	Shares	Sole	2025-02-14
2024-09-30	$300,629	100,545	+897.0%	Shares	Sole	2024-11-14
2024-06-30	$30,053	10,085	-16.5%	Shares	Sole	2024-08-14
2024-03-31	$142,567	12,082	-46.6%	Shares	Sole	2024-05-15
2023-12-31	$184,061	22,612	-50.0%	Shares	Sole	2024-02-14
2023-09-30	$367,435	45,195	-47.5%	Shares	Sole	2023-11-14
2023-06-30	$640,680	86,113	—	Shares	Sole	2023-08-14
No filing history on record for this holder in this stock.