Prosight Management, LP
Filing Date
Global Rank
#2,353
/ 8,622
▲ 361
· as of Mar 2026
Top Industry
Biotechnology
60.4%
3Y Alpha vs SPY
-13.4%
Period ended 4 months ago
Filed May 15, 2026 · 2mo
25 quarters · since Mar 2020
Clone Performance
Jul 2023–Jul 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+17.2%
SPY
+67.9%
Annualised alpha
-13.4%
Max drawdown
−44.8%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 100% of reported value on average across 13 quarters. Past performance does not predict future results.
Portfolio Concentration
46 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
8.7%
−0.3 pts
Top 5
40.6%
+5.9 pts
Top 10
65.0%
+7.8 pts
HHI
518
Diversified+68
Portfolio Trend
25 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 99.8% | $608,845,822 |
| Industrials | 0.2% | $974,008 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
19 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| STTK | Shattuck Labs, Inc. | +2,622,937 | 5,004,439 | $32,178,542 | |
| OKUR | OnKure Therapeutics, Inc. | +1,337,472 | 2,154,381 | $8,919,137 | |
| JANX | Janux Therapeutics, Inc. | +1,157,477 | 3,550,000 | $49,345,000 | |
| KURA | Kura Oncology, Inc. | +827,100 | 3,356,700 | $27,289,971 | |
| BSX | Boston Scientific Corp | +585,547 | 795,547 | $49,920,574 | |
| PRCT | PROCEPT BioRobotics Corp | +565,000 | 1,945,000 | $48,644,450 | |
| LKFT | Lakefront Biotherapeutics NV | +475,888 | 1,550,000 | $46,500,000 | |
| WGS | GeneDx Holdings Corp. | +468,463 | 523,463 | $33,616,793 | |
| NKTR | Nektar Therapeutics | +180,367 | 735,000 | $52,883,250 | |
| KIDS | Orthopediatrics Corp | +165,658 | 302,399 | $4,799,072 | |
| PHR | Phreesia, Inc. | +122,848 | 1,100,000 | $9,218,000 | |
| PLRX | Pliant Therapeutics, Inc. | +111,856 | 1,667,600 | $2,101,176 | |
| TERN | Terns Pharmaceuticals, Inc. | +107,300 | 202,300 | $10,665,256 | |
| SNDX | Syndax Pharmaceuticals Inc | +105,000 | 770,000 | $17,987,200 | |
| ABVX | Abivax S.A. | +88,000 | 105,000 | $11,691,750 | |
| CRNX | Crinetics Pharmaceuticals, Inc. | +87,096 | 350,000 | $12,712,000 | |
| ALNY | Alnylam Pharmaceuticals, Inc. | +58,891 | 76,000 | $25,146,120 | |
| CRBP | Corbus Pharmaceuticals Holdings, Inc. | +13,236 | 697,108 | $6,545,844 | |
| ZYME | Zymeworks Inc. | +8,656 | 539,049 | $13,497,786 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
10 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| MGTX | MeiraGTx Holdings plc | −579,817 | 2,629,971 | $22,775,548 | |
| ROIV | Roivant Sciences Ltd. | −447,162 | 180,000 | $4,986,000 | |
| CON | Concentra Group Holdings Parent, Inc. | −385,208 | 505,822 | $10,849,881 | |
| TBI | TrueBlue, Inc. | −193,447 | 249,107 | $974,008 | |
| ADCT | ADC Therapeutics SA | −177,338 | 8,300,000 | $31,125,000 | |
| TECX | Tectonic Therapeutic, Inc. | −155,128 | 79,872 | $2,468,843 | |
| IMVT | Immunovant, Inc. | −67,579 | 175,825 | $4,367,493 | |
| RCKT | Rocket Pharmaceuticals, Inc. | −60,086 | 683,856 | $2,448,204 | |
| RNTX | Rein Therapeutics, Inc. | −31,000 | 411,600 | $535,080 | |
| VEEV | Veeva Systems Inc | −3,653 | 86,480 | $15,191,076 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
16 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ALKS | Alkermes plc. | 513,632 | $18,162,027 | |
| SDGR | Schrodinger, Inc. | 510,578 | $5,800,166 | |
| EBS | Emergent BioSolutions Inc. | 639,118 | $5,304,679 | |
| ICUI | Icu Medical Inc/De | 27,450 | $3,545,167 | |
| UPB | Upstream Bio, Inc. | 241,123 | $2,170,107 | |
| OMER | Omeros Corp | 174,800 | $1,845,888 | |
| ISRG | Intuitive Surgical Inc | 4,000 | $1,843,960 | |
| ANTX | AN2 Therapeutics, Inc. | 515,754 | $1,763,878 | |
| RGNX | REGENXBIO Inc. | 200,000 | $1,676,000 | |
| COYA | Coya Therapeutics, Inc. | 420,360 | $1,656,218 | |
| VKTX | Viking Therapeutics, Inc. | 45,000 | $1,464,300 | |
| IRTC | iRhythm Holdings, Inc. | 10,000 | $1,180,200 | |
| IMRX | Immuneering Corp | 123,409 | $650,365 | |
| PVLA | Palvella Therapeutics, Inc. | 5,000 | $623,250 | |
| NVCR | NovoCure Ltd | 50,400 | $549,360 | |
| TMDX | TransMedics Group, Inc. | 5,000 | $497,050 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
8 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ICLR | Icon PLC | 110,000 | $20,044,200 | |
| FOLD | AMICUS THERAPEUTICS, INC. | 1,150,000 | $16,376,000 | |
| SEM | Select Medical Holdings Corp | 1,035,086 | $15,371,027 | |
| AVTR | Avantor, Inc. | 898,499 | $10,296,798 | |
| LH | Labcorp Holdings Inc. | 34,532 | $8,663,388 | |
| CDNA | CareDx, Inc. | 250,000 | $4,710,000 | |
| BBIO | BridgeBio Pharma, Inc. | 30,000 | $2,294,700 | |
| TEM | Tempus AI, Inc. | 35,000 | $2,066,750 | |
| No positions match the current search. | ||||
46 tracked positions ·
$609,819,830 total
· filing declares
46 positions · $609,819,841
· as of Mar 31, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| NKTR |
Nektar Therapeutics
Healthcare
|
Added | 735,000 | $52,883,250 | 8.67% | |
| BSX |
Boston Scientific Corp
Healthcare
|
Added | 795,547 | $49,920,574 | 8.19% | |
| JANX |
Janux Therapeutics, Inc.
Healthcare
|
Added | 3,550,000 | $49,345,000 | 8.09% | |
| PRCT |
PROCEPT BioRobotics Corp
Healthcare
|
Added | 1,945,000 | $48,644,450 | 7.98% | |
| LKFT |
Lakefront Biotherapeutics NV
Healthcare
|
Added | 1,550,000 | $46,500,000 | 7.63% | |
| WGS |
GeneDx Holdings Corp.
Healthcare
|
Added | 523,463 | $33,616,793 | 5.51% | |
| STTK |
Shattuck Labs, Inc.
Healthcare
|
Added | 5,004,439 | $32,178,542 | 5.28% | |
| ADCT |
ADC Therapeutics SA
Healthcare
|
Reduced | 8,300,000 | $31,125,000 | 5.10% | |
| KURA |
Kura Oncology, Inc.
Healthcare
|
Added | 3,356,700 | $27,289,971 | 4.48% | |
| ALNY |
Alnylam Pharmaceuticals, Inc.
Healthcare
|
Added | 76,000 | $25,146,120 | 4.12% | |
| MGTX |
MeiraGTx Holdings plc
Healthcare
|
Reduced | 2,629,971 | $22,775,548 | 3.73% | |
| ALKS |
Alkermes plc.
Healthcare
|
NEW | 513,632 | $18,162,027 | 2.98% | |
| SNDX |
Syndax Pharmaceuticals Inc
Healthcare
|
Added | 770,000 | $17,987,200 | 2.95% | |
| VEEV |
Veeva Systems Inc
Healthcare
|
Reduced | 86,480 | $15,191,076 | 2.49% | |
| ZYME |
Zymeworks Inc.
Healthcare
|
Added | 539,049 | $13,497,786 | 2.21% | |
| CRNX |
Crinetics Pharmaceuticals, Inc.
Healthcare
|
Added | 350,000 | $12,712,000 | 2.08% | |
| ABVX |
Abivax S.A.
Healthcare
|
Added | 105,000 | $11,691,750 | 1.92% | |
| CON |
Concentra Group Holdings Parent, Inc.
Healthcare
|
Reduced | 505,822 | $10,849,881 | 1.78% | |
| TERN |
Terns Pharmaceuticals, Inc.
Healthcare
|
Added | 202,300 | $10,665,256 | 1.75% | |
| PHR |
Phreesia, Inc.
Healthcare
|
Added | 1,100,000 | $9,218,000 | 1.51% | |
| OKUR |
OnKure Therapeutics, Inc.
Healthcare
|
Added | 2,154,381 | $8,919,137 | 1.46% | |
| CRBP |
Corbus Pharmaceuticals Holdings, Inc.
Healthcare
|
Added | 697,108 | $6,545,844 | 1.07% | |
| SDGR |
Schrodinger, Inc.
Healthcare
|
NEW | 510,578 | $5,800,166 | 0.95% | |
| EBS |
Emergent BioSolutions Inc.
Healthcare
|
NEW | 639,118 | $5,304,679 | 0.87% | |
| ROIV |
Roivant Sciences Ltd.
Healthcare
|
Reduced | 180,000 | $4,986,000 | 0.82% | |
| KIDS |
Orthopediatrics Corp
Healthcare
|
Added | 302,399 | $4,799,072 | 0.79% | |
| IMVT |
Immunovant, Inc.
Healthcare
|
Reduced | 175,825 | $4,367,493 | 0.72% | |
| ICUI |
Icu Medical Inc/De
Healthcare
|
NEW | 27,450 | $3,545,167 | 0.58% | |
| TECX |
Tectonic Therapeutic, Inc.
Healthcare
|
Reduced | 79,872 | $2,468,843 | 0.40% | |
| RCKT |
Rocket Pharmaceuticals, Inc.
Healthcare
|
Reduced | 683,856 | $2,448,204 | 0.40% | |
| UPB |
Upstream Bio, Inc.
Healthcare
|
NEW | 241,123 | $2,170,107 | 0.36% | |
| PLRX |
Pliant Therapeutics, Inc.
Healthcare
|
Added | 1,667,600 | $2,101,176 | 0.34% | |
| OMER |
Omeros Corp
Healthcare
|
NEW | 174,800 | $1,845,888 | 0.30% | |
| ISRG |
Intuitive Surgical Inc
Healthcare
|
NEW | 4,000 | $1,843,960 | 0.30% | |
| ANTX |
AN2 Therapeutics, Inc.
Healthcare
|
NEW | 515,754 | $1,763,878 | 0.29% | |
| ACET |
Adicet Bio, Inc.
Healthcare
|
Held | 250,244 | $1,704,161 | 0.28% | |
| RGNX |
REGENXBIO Inc.
Healthcare
|
NEW | 200,000 | $1,676,000 | 0.27% | |
| COYA |
Coya Therapeutics, Inc.
Healthcare
|
NEW | 420,360 | $1,656,218 | 0.27% | |
| VKTX |
Viking Therapeutics, Inc.
Healthcare
|
NEW | 45,000 | $1,464,300 | 0.24% | |
| IRTC |
iRhythm Holdings, Inc.
Healthcare
|
NEW | 10,000 | $1,180,200 | 0.19% | |
| TBI |
TrueBlue, Inc.
Industrials
|
Reduced | 249,107 | $974,008 | 0.16% | |
| IMRX |
Immuneering Corp
Healthcare
|
NEW | 123,409 | $650,365 | 0.11% | |
| PVLA |
Palvella Therapeutics, Inc.
Healthcare
|
NEW | 5,000 | $623,250 | 0.10% | |
| NVCR |
NovoCure Ltd
Healthcare
|
NEW | 50,400 | $549,360 | 0.09% | |
| RNTX |
Rein Therapeutics, Inc.
Healthcare
|
Reduced | 411,600 | $535,080 | 0.09% | |
| TMDX |
TransMedics Group, Inc.
Healthcare
|
NEW | 5,000 | $497,050 | 0.08% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.