TWO SIGMA INVESTMENTS, LP

Position in ASMB — Assembly Biosciences, Inc.

CIK 1179392 NEW YORK, NY

Position in ASMB

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$490,737

-$79,525 QoQ

Shares Held

17,858

-13.1% QoQ

Ownership

0.088%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#50

of 92 holders

Holding Since

Mar 2020

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. ASMB ranks #249 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$490,737	17,858	-13.1%	Shares	Sole	2026-08-14
2026-03-31	$570,262	20,550	-84.8%	Shares	Sole	2026-05-15
2023-12-31	$110,739	135,048	+252.6%	Shares	Sole	2024-02-14
2023-03-31	$32,174	38,303	+19.4%	Shares	Sole	2023-05-15
2022-09-30	$52,589	32,067	-48.6%	Shares	Sole	2022-11-14
2022-06-30	$131,119	62,438	-67.2%	Shares	Sole	2022-08-15
2021-12-31	$443,378	190,291	-70.6%	Shares	Sole	2022-02-14
2021-06-30	$2,507,713	646,318	+16.7%	Shares	Sole	2021-08-16
2021-03-31	$2,547,456	553,795	+3925.0%	Shares	Sole	2021-05-17
2020-09-30	$226,197	13,759	-82.2%	Shares	Sole	2020-11-16
2020-06-30	$1,799,254	77,155	+44.7%	Shares	Sole	2020-08-14
2020-03-31	$790,928	53,333	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.