TWO SIGMA INVESTMENTS, LP

Position in AUPH — Aurinia Pharmaceuticals Inc.

CIK 1179392 NEW YORK, NY

Position in AUPH

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$58,843,712

+$8,030,304 QoQ

Shares Held

3,467,514

+1.1% QoQ

Ownership

2.61%

of shares outstanding

% of Portfolio

0.05%

of 13F equity value

Holder Rank

of 279 holders

Holding Since

Mar 2020

14 quarters on record

Voting authority Sole 98% Shared 0% None 2%

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,273,624,947 across 342 Biotechnology names. AUPH ranks #34 (0.8% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,875,937	$564,713,315
2	MRNA	Moderna, Inc.	7,193,530	$503,762,905
3	IONS	Ionis Pharmaceuticals Inc	6,252,342	$495,748,197
4	REGN	Regeneron Pharmaceuticals, Inc.	656,124	$409,119,558
5	BBIO	BridgeBio Pharma, Inc.	4,722,185	$351,708,338
6	EXEL	Exelixis, Inc.	4,209,861	$229,058,537
7	INCY	Incyte Corp	2,003,559	$227,123,448
8	ARGX	Argenx SE	185,638	$172,229,367

14 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$58,843,712	3,467,514	+1.1%	Shares	Sole	2026-08-14
2026-03-31	$50,813,408	3,428,705	+74.7%	Shares	Sole	2026-05-15
2025-12-31	$31,305,734	1,962,742	+46.4%	Shares	Sole	2026-02-17
2025-09-30	$14,818,790	1,341,067	+728.6%	Shares	Sole	2025-11-14
2025-06-30	$1,370,852	161,848	+51.4%	Shares	Sole	2025-08-14
2025-03-31	$859,379	106,888	-38.4%	Shares	Sole	2025-05-15
2023-12-31	$1,560,664	173,600	-72.4%	Shares	Sole	2024-02-14
2023-09-30	$4,882,046	628,320	-54.1%	Shares	Sole	2023-11-14
2023-06-30	$13,243,895	1,368,171	+89.1%	Shares	Sole	2023-08-14
2023-03-31	$7,930,677	723,602	+15.7%	Shares	Sole	2023-05-15
2022-12-31	$2,700,747	625,173	+19.3%	Shares	Sole	2023-02-14
2022-09-30	$3,942,329	524,246	+4710.0%	Shares	Sole	2022-11-14
2020-09-30	$160,542	10,899	-55.7%	Shares	Sole	2020-11-16
2020-03-31	$356,931	24,599	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.