GYRE · Gyre Therapeutics, Inc.

$6.57 -0.02 (-0.30%) At close · Aug 31

Russell 2000 member Rebalance outlook locked

Market Cap

$734.85M

111.51M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 61

Total Value: $57,104,773

Total Shares: 8,665,375

Institutional Ownership Trend

11 quarters

Holder Concentration

Across 61 13F filers · Δ vs Mar 31, 2026

Top Holder

43.3%

+14.4 pts

Top 5

82.0%

+6.9 pts

Top 10

92.6%

+0.4 pts

HHI

2,294

Moderately concentrated+669

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +5

Institutional value: +140.5%

Shares held: +154.3%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega BlackRock, Inc.	+235,313	993,943
Mega GEODE CAPITAL MANAGEMENT, LLC	+101,536	532,950
Mega VANGUARD PORTFOLIO MANAGEMENT LLC	+54,139	123,953
Mega NORTHERN TRUST CORP	+35,696	169,537
Mega MORGAN STANLEY	+33,050	41,691

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega VANGUARD CAPITAL MANAGEMENT LLC	−107,277	876,927
Mid SBI Securities Co., Ltd.	−4,087	166,750
Mega FMR LLC	−3,743	14,974
Mid Tower Research Capital LLC (TRC)	−3,294	2,469
Mega UBS Group AG	−2,324	18,763

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mid HSG Holding Ltd	3,750,299	$24,714,470
Mid Octagon Capital Advisors LP	954,416	$6,289,601
Mega Nuveen, LLC	24,505	$161,487
Mega MILLENNIUM MANAGEMENT LLC	18,488	$121,835
Mega PRICE T ROWE ASSOCIATES INC /MD/	15,031	$99,054

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mid Brevan Howard Capital Management LP	13,808	$96,241
Mid SIMPLEX TRADING, LLC	674	$4,697
Large CWM, LLC	104	$724
Large NISA INVESTMENT ADVISORS, LLC	102	$710
Large US BANCORP \DE\	98	$683

Filter: New 12 Increased 31 Reduced 10 Sold out 7 Unchanged 8

Showing 61 of 61

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

HSG Holding Ltd

$24,714,470

43.28%

3,750,299

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SNP China Enterprises Ltd	3,750,299	$24,714,470	100.0%	Defined

BlackRock, Inc.

$6,550,081

11.47%

993,943

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	4,363	$28,752	0.4%	Sole
BlackRock Investment Management, LLC	47,198	$311,034	4.7%	Sole
BLACKROCK ADVISORS LLC	46,262	$304,866	4.7%	Sole
BlackRock Fund Advisors	558,305	$3,679,229	56.2%	Sole
BlackRock Institutional Trust Company, N.A.	335,257	$2,209,343	33.7%	Sole
Aperio Group, LLC	2,558	$16,857	0.3%	Sole

Octagon Capital Advisors LP

$6,289,601

11.01%

954,416

VANGUARD CAPITAL MANAGEMENT LLC

$5,778,948

10.12%

876,927

GEODE CAPITAL MANAGEMENT, LLC

$3,512,140

6.15%

532,950

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	76,824	$506,270	14.4%	Defined
Held directly	456,126	$3,005,870	85.6%	Defined

STATE STREET CORP

$1,617,199

2.83%

245,402

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	245,402	$1,617,199	100.0%	Defined

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$1,214,444

2.13%

184,286

NORTHERN TRUST CORP

$1,117,247

1.96%

169,537

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	166,671	$1,098,361	98.3%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	2,866	$18,886	1.7%	Other

SBI Securities Co., Ltd.

$1,098,882

1.92%

166,750

VANGUARD FIDUCIARY TRUST CO

$995,571

1.74%

151,073

VANGUARD PORTFOLIO MANAGEMENT LLC

$816,850

1.43%

123,953

GOLDMAN SACHS GROUP INC

$568,288

1.00%

86,235

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	86,235	$568,288	100.0%	Defined

Bank of New York Mellon Corp

$413,521

0.72%

62,750

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	34,588	$227,934	55.1%	Defined
The Bank of New York Mellon	28,162	$185,587	44.9%	Defined

MORGAN STANLEY

$274,741

0.48%

41,691

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	36	$237	0.1%	Defined
MORGAN STANLEY & CO. LLC	4,887	$32,205	11.7%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	32,451	$213,852	77.8%	Defined
MORGAN STANLEY SMITH BARNEY LLC	292	$1,924	0.7%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	4,025	$26,523	9.7%	Defined

STRS OHIO

$170,022

0.30%

25,800

DIMENSIONAL FUND ADVISORS LP

$166,515

0.29%

25,268

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Ireland Ltd	758	$4,995	3.0%	Defined
Held directly	24,510	$161,520	97.0%	Sole

ALLIANCEBERNSTEIN L.P.

$162,048

0.28%

24,590

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	24,590	$162,048	100.0%	Defined

Nuveen, LLC

$161,487

0.28%

24,505

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TEACHERS ADVISORS, LLC joint	24,505	$161,487	100.0%	Defined

UBS Group AG

$123,646

0.22%

18,763

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	25	$164	0.1%	Defined
UBS AG	17,879	$117,822	95.3%	Defined
UBS Securities LLC	859	$5,660	4.6%	Defined

MILLENNIUM MANAGEMENT LLC

$121,835

0.21%

18,488

DEUTSCHE BANK AG\

$118,217

0.21%

17,939

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	37	$243	0.2%	Defined
DWS Investments UK Ltd	17,902	$117,974	99.8%	Defined

RHUMBLINE ADVISERS

$111,140

0.19%

16,865

WELLS FARGO & COMPANY/MN

$107,396

0.19%

16,297

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	16,231	$106,962	99.6%	Defined
Wells Fargo Securities, LLC	66	$434	0.4%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$99,054

0.17%

15,031

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	15,031	$99,054	100.0%	Defined

FMR LLC

$98,678

0.17%

14,974

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	14,974	$98,678	100.0%	Defined

ROYAL BANK OF CANADA

$86,953

0.15%

13,195

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	537	$3,538	4.1%	Defined
RBC Capital Markets, LLC	2,128	$14,023	16.1%	Defined
Held directly	10,530	$69,392	79.8%	Sole

BANK OF AMERICA CORP /DE/

$82,539

0.14%

12,525

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	12,525	$82,539	100.0%	Defined

Polymer Capital Management (US) LLC

$77,630

0.14%

11,780

Vanguard Global Advisers, LLC

$65,787

0.12%

9,983

Police & Firemen's Retirement System of New Jersey

$59,382

0.10%

9,011

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	9,011	$59,382	100.0%	Defined

CITIGROUP INC

$56,580

0.10%

8,586

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	8,586	$56,580	100.0%	Defined

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$55,659

0.10%

8,446

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	8,446	$55,659	100.0%	Defined

JPMORGAN CHASE & CO

$51,605

0.09%

7,831

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	7,604	$50,110	97.1%	Defined
J.P. Morgan Investment Management Inc.	56	$369	0.7%	Defined
J.P. Morgan Securities plc	171	$1,126	2.2%	Defined

State of Alaska, Department of Revenue

$34,393

0.06%

5,219

Russell Investments Group, Ltd.

$24,929

0.04%

3,783

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	3,783	$24,929	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$22,972

0.04%

3,486

BARCLAYS PLC

$21,272

0.04%

3,228

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	2,816	$18,557	87.2%	Defined
BARCLAYS CAPITAL INC.	412	$2,715	12.8%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$17,793

0.03%

2,700

Tower Research Capital LLC (TRC)

$16,270

0.03%

2,469

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	2,469	$16,270	100.0%	Defined

Legal & General Group Plc

$13,535

0.02%

2,054

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	2,054	$13,535	100.0%	Defined

Ameritas Investment Partners, Inc.

$4,500

0.01%

683

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	683	$4,500	100.0%	Other

Activest Wealth Management

$3,512

0.01%

533

Arax Advisory Partners

$1,621

0.00%

246

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$1,093

0.00%

166

Sterling Capital Management LLC

$1,060

0.00%

161

GAMMA Investing LLC

$962

0.00%

146

Physician Wealth Advisors, Inc.

$540

0.00%

Bare Financial Services, Inc

$520

0.00%

GoalVest Advisory LLC

$329

0.00%

Covestor Ltd

$316

0.00%

OSAIC HOLDINGS, INC.

$289

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	33	$217	75.1%	Defined
Osaic Advisory Services, LLC	11	$72	24.9%	Defined

Allworth Financial LP

$250

0.00%

EverSource Wealth Advisors, LLC

$129

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMSS Wesson Wealth Solutions, LLC	5	$32	24.8%	Sole
Held directly	15	$97	75.2%	Sole

Caitong International Asset Management Co., Ltd

$98

0.00%

Integrated Wealth Concepts LLC

$92

0.00%

Farther Finance Advisors, LLC

$52

0.00%

Optiver Holding B.V.

$39

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Optiver VOF	6	$39	100.0%	Defined

Smartleaf Asset Management LLC

$39

0.00%

ROTHSCHILD INVESTMENT LLC

0.00%

Essential Partners LLC

0.00%

MassMutual Private Wealth & Trust, FSB

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Brevan Howard US Investment Management, LP	13,808	$96,241	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	98	$683	100.0%	Defined

Key facts CIK 1124105 CUSIP 403783103 13F (30d) 47 filings 47 filers Visit website Investor relations