Position in KPTI
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$6,792,729
+$5,950,367 QoQ
Shares Held
695,264
+359.7% QoQ
Ownership
3.07%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#10
of 96 holders
Holding Since
Mar 2020
21 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in KPTI Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. KPTI ranks #101 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in KPTI
Export CSV
21 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $6,792,729 | 695,264 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $842,362 | 151,232 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $1,095,116 | 148,793 | Shares | Sole | 2026-02-17 | |
| 2024-12-31 | $93,143 | 137,786 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $71,321 | 85,930 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $12,035 | 13,866 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $20,673 | 13,691 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $123,067 | 142,274 | Shares | Sole | 2024-02-14 | |
| 2023-06-30 | $622,123 | 347,555 | Shares | Sole | 2023-08-14 | |
| 2022-12-31 | $902,047 | 265,308 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $1,246,709 | 228,335 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $4,617,121 | 1,023,752 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $8,239,107 | 1,117,925 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $6,359,469 | 989,031 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $6,382,695 | 1,096,683 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $8,731,937 | 846,118 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $15,702,593 | 1,492,642 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $622,481 | 40,212 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $18,799,719 | 1,287,652 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $4,464,801 | 235,734 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $8,406,718 | 437,622 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||