Skip to main content
Equibles

TWO SIGMA INVESTMENTS, LP

Position in LYEL — Lyell Immunopharma, Inc.

CIK 1179392 NEW YORK, NY
Back to LYEL Full portfolio

Position in LYEL

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$743,624
+$511,229 QoQ
Shares Held
52,927
+356.9% QoQ
Ownership
0.216%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#28
of 87 holders
Holding Since
Dec 2021
16 quarters on record
Voting authority Sole 99% Shared 0% None 1%

Common Shares in LYEL Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. LYEL ranks #220 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 ALNY
Alnylam Pharmaceuticals, Inc.
 1,875,937 $564,713,315
2 MRNA
Moderna, Inc.
 7,193,530 $503,762,905
3 IONS
Ionis Pharmaceuticals Inc
 6,252,342 $495,748,197
4 REGN
Regeneron Pharmaceuticals, Inc.
 656,124 $409,119,558
5 BBIO
BridgeBio Pharma, Inc.
 4,722,185 $351,708,338
6 EXEL
Exelixis, Inc.
 4,209,861 $229,058,537
7 INCY
Incyte Corp
 2,003,559 $227,123,448
8 ARGX
Argenx SE
 185,638 $172,229,367

All Filings in LYEL

Export CSV
16 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $743,624 52,927
2026-03-31 $232,395 11,585
2025-12-31 $480,660 15,616
2025-09-30 $338,230 20,827
2025-06-30 $88,921 10,059
2025-03-31 $208,571 387,680
2024-12-31 $130,880 204,501
2024-09-30 $333,733 241,836
2024-06-30 $577,363 398,182
2024-03-31 $955,755 428,590
2023-12-31 $468,482 241,486
2023-09-30 $73,353 49,900
2023-06-30 $177,444 55,800
2023-03-31 $910,950 385,996
2022-12-31 $570,183 164,318
2021-12-31 $563,108 72,753