Position in NTLA
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$60,329,650
+$36,067,996 QoQ
Shares Held
4,705,901
+74.4% QoQ
Ownership
3.37%
of shares outstanding
% of Portfolio
0.06%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in NTLA Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. NTLA ranks #18 (1.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in NTLA
Export CSV
25 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $60,329,650 | 4,705,901 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $24,261,654 | 2,698,738 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $42,304,712 | 2,449,607 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $21,354,264 | 2,276,574 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $14,169,554 | 1,992,905 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $21,498,043 | 1,843,743 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $20,146,809 | 980,380 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $18,559,398 | 829,285 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $16,906,765 | 614,568 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $15,485,474 | 507,887 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $5,185,363 | 163,990 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $1,749,462 | 42,900 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $5,223,688 | 140,158 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $6,992,444 | 200,414 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $5,125,656 | 91,595 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $21,765,235 | 420,503 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $34,754,645 | 478,253 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $23,430,556 | 198,161 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $41,607,159 | 310,154 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $7,584,188 | 46,842 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $27,824,729 | 346,704 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $15,457,107 | 284,138 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $4,950,517 | 249,020 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $5,717,734 | 272,014 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $1,946,942 | 159,194 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||