6-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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FORM 6-K

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REPORT OF FOREIGN PRIVATE ISSUER

Pursuant to Rule 13a-16 or 15d-16

of the Securities Exchange Act of 1934

February 20, 2026

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NOVO NORDISK A/S

(Exact name of Registrant as specified in its charter)

Novo Allé 1

DK- 2880, Bagsvaerd

Denmark

(Address of principal executive offices)

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Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F

Notice for the Annual General Meeting of Novo Nordisk A/S

Bagsværd, Denmark, 20 February 2026 – The Annual General Meeting will be held on:

Thursday 26 March 2026 at 14:00 (CET)

The Annual General Meeting will be held as a combined physical and virtual meeting. Accordingly, shareholders can choose between participating in person at Bella Center, Center Boulevard 5, entrance 6, 2300 Copenhagen S, Denmark, or virtually by PC or smartphone/tablet. We encourage shareholders to exercise their rights by submitting proxies or votes by correspondence in advance of the Annual General Meeting. Further details on registration and participation are included in the enclosed meeting notice.

Novo Nordisk offers shareholders and others to follow the Annual General Meeting via live webcast on Novo Nordisk’s website. Please refer to the enclosed meeting notice for further information on the webcast.

BOARD OF DIRECTORS

All shareholder-elected Board members are up for election.

The Board of Directors proposes re-election of Lars Rebien Sørensen as Chair of the Board and re-election of Cees de Jong as Vice Chair. Moreover, the Board proposes re-election of Britt Meelby Jensen, Stephan Engels and Kasim Kutay. The Board proposes Helena Saxon, Jan van de Winkel and Ramona Sequeira as new members of the Board of Directors.

Novo Nordisk is a leading global healthcare company founded in 1923 and headquartered in Denmark.Our purpose is to drive change to defeat serious chronic diseases built upon our heritage in diabetes. We do so by pioneering scientificbreakthroughs, expanding access to our medicines and working to prevent and ultimately cure disease. Novo Nordisk employs about 68,800people in 80 countries and markets its products in around 170 countries. Novo Nordisk's B shares are listed on Nasdaq Copenhagen (Novo-B).Its ADRs are listed on the New York Stock Exchange (NVO). For more information, visit novonordisk.com, Facebook, Instagram, X, LinkedInand YouTube.

Contacts for further information

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf of the undersigned, thereunto duly authorized.