SERA · Sera Prognostics, Inc. · Holdings

$2.03 -0.02 (-0.98%) At close · Sep 11

Market Cap

$80.08M

39.45M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Quarter:

Holders: 46

Total Value: $31,043,064

Total Shares: 17,056,642

Institutional Ownership Trend

20 quarters

Holder Concentration

Across 46 13F filers · Δ vs Mar 31, 2026

Top Holder

32.2%

+4.7 pts

Top 5

85.1%

+7.9 pts

Top 10

93.8%

+3.1 pts

HHI

1,847

Moderately concentrated+382

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: -10

Institutional value: -23.4%

Shares held: -14.5%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large Aberdeen Group plc	+202,750	2,753,525
Mega VANGUARD CAPITAL MANAGEMENT LLC	+93,677	1,297,792
Mega Qube Research & Technologies Ltd	+30,954	50,871
Mega BlackRock, Inc.	+25,264	221,369
Mid Catalyst Funds Management Pty Ltd	+15,326	38,890

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega CITADEL ADVISORS LLC	−222,298	41,411
Mega MORGAN STANLEY	−54,045	50,972
Mega BARCLAYS PLC	−28,788	3,179
Mega NORTHERN TRUST CORP	−27,940	68,595
Mega MILLENNIUM MANAGEMENT LLC	−17,518	73,986

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)	Open
Mid Global Retirement Partners, LLC	1,000	$1,820

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Micro PSP Research LLC	2,396,685	$4,865,270
Small SANDERS MORRIS HARRIS LLC	314,950	$639,348
Mid GSA CAPITAL PARTNERS LLP	104,973	$213,095
Mega JANE STREET GROUP, LLC	53,908	$109,432
Large Squarepoint Ops LLC	31,428	$63,798

Filter: New 1 Increased 11 Reduced 13 Sold out 11 Unchanged 21

Showing 46 of 46

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BAKER BROS. ADVISORS LP

$10,006,669

32.23%

5,498,170

Whetstone Capital Advisors, LLC

$6,018,537

19.39%

3,306,889

Aberdeen Group plc

$5,011,415

16.14%

2,753,525

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	2,753,525	$5,011,415	100.0%	Defined

Vivo Capital, LLC

$3,003,800

9.68%

1,650,440

VANGUARD CAPITAL MANAGEMENT LLC

$2,361,981

7.61%

1,297,792

CAPTRUST FINANCIAL ADVISORS

$975,074

3.14%

535,755

GEODE CAPITAL MANAGEMENT, LLC

$635,119

2.05%

348,967

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	69,040	$125,652	19.8%	Defined
Held directly	279,927	$509,467	80.2%	Defined

BlackRock, Inc.

$402,890

1.30%

221,369

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BlackRock Investment Management, LLC	6,973	$12,690	3.1%	Sole
BlackRock Fund Advisors	102,359	$186,293	46.2%	Sole
BlackRock Institutional Trust Company, N.A.	112,037	$203,907	50.6%	Sole

AWM Investment Company, Inc.

$377,435

1.22%

207,382

VANGUARD FIDUCIARY TRUST CO

$311,052

1.00%

170,908

STATE STREET CORP

$227,121

0.73%

124,792

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS TRUST COMPANY	124,792	$227,121	100.0%	Defined

MILLENNIUM MANAGEMENT LLC

$134,654

0.43%

73,986

Perigon Wealth Management, LLC

$132,286

0.43%

72,685

NORTHERN TRUST CORP

$124,842

0.40%

68,595

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	68,595	$124,842	100.0%	Defined

Bank of New York Mellon Corp

$110,886

0.36%

60,927

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
The Bank of New York Mellon	1,967	$3,579	3.2%	Defined
Newton Investment Management North America, LLC	58,960	$107,307	96.8%	Defined

BRIDGEWAY CAPITAL MANAGEMENT, LLC

$101,383

0.33%

55,705

Requisite Capital Management, LLC

$101,279

0.33%

55,648

MORGAN STANLEY

$92,769

0.30%

50,972

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY SMITH BARNEY LLC	50,972	$92,769	100.0%	Defined

Qube Research & Technologies Ltd

$92,585

0.30%

50,871

Ballentine Partners, LLC

$90,388

0.29%

49,664

Twelve Points Wealth Management LLC

$78,966

0.25%

43,388

HighTower Advisors, LLC

$76,865

0.25%

42,234

CITADEL ADVISORS LLC

$75,368

0.24%

41,411

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	41,411	$75,368	100.0%	Defined

Catalyst Funds Management Pty Ltd

$70,779

0.23%

38,890

GOLDMAN SACHS GROUP INC

$59,224

0.19%

32,541

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	32,541	$59,224	100.0%	Defined

DIMENSIONAL FUND ADVISORS LP

$53,687

0.17%

29,499

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	3,634	$6,613	12.3%	Defined
Dimensional Ireland Ltd	2,332	$4,244	7.9%	Defined
Held directly	23,533	$42,830	79.8%	Sole

Birch Hill Investment Advisors LLC

$49,673

0.16%

27,293

Cetera Investment Advisers

$45,500

0.15%

25,000

XTX Topco Ltd

$30,590

0.10%

16,808

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	16,808	$30,590	100.0%	Defined

TWO SIGMA INVESTMENTS, LP

$29,522

0.10%

16,221

Riverview Capital Advisers, LLC

$23,057

0.07%

12,669

Wagner Wealth Management, LLC

$22,568

0.07%

12,400

Focus Partners Wealth

$22,123

0.07%

12,156

UBS Group AG

$20,581

0.07%

11,309

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	11,269	$20,509	99.7%	Defined
UBS Securities LLC	40	$72	0.3%	Defined

Vanguard Global Advisers, LLC

$20,327

0.07%

11,169

Geneos Wealth Management Inc.

$19,656

0.06%

10,800

WEALTH ENHANCEMENT ADVISORY SERVICES, LLC

$19,117

0.06%

10,504

BARCLAYS PLC

$5,785

0.02%

3,179

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS CAPITAL INC.	3,179	$5,785	100.0%	Defined

FMR LLC

$4,620

0.01%

2,539

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	2,539	$4,620	100.0%	Defined

Global Retirement Partners, LLC

$1,820

0.01%

1,000

JPMORGAN CHASE & CO

$404

0.00%

222

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Securities plc	222	$404	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$338

0.00%

186

NISA INVESTMENT ADVISORS, LLC

$234

0.00%

129

ROYAL BANK OF CANADA

$81

0.00%

SBI Securities Co., Ltd.

0.00%

Caitong International Asset Management Co., Ltd

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	35,229	$71,514	65.4%	Defined
Jane Street Global Trading, LLC	18,679	$37,918	34.6%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	31,428	$63,798	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Optiver VOF	412	$836	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Institutional Asset Management Trust Co	19	$38	100.0%	Sole

Key facts CIK 1534969 CUSIP 81749D107 13F (30d) 13 filings 13 filers Visit website Investor relations