TNXP · Tonix Pharmaceuticals Holding Corp.

Shares acquired through the Tonix Pharmaceuticals Holding Corp. 2025 Employee Stock Purchase Plan.

Represents the weighted average purchase price of shares purchased in a series of open market transactions on the transaction date at prices ranging from $11.735 to $11.883 per share. The Reporting Person undertakes to provide, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price.

Represents the weighted average purchase price of shares purchased in a series of open market transactions on the transaction date at prices ranging from $11.63 to $11.65 per share. The Reporting Person undertakes to provide, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan, and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan, and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan, and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's 2026 Stock Incentive Plan, and vests on the earlier of the one year anniversary of the grant date and the Issuer's 2027 Annual Meeting of Stockholders.

Represents the weighted average purchase price of shares purchased in a series of open market transactions on the transaction date at prices ranging from $12.5699 to $12.625 per share. The Reporting Persons undertakes to provide, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price.

Reporting person may be deemed a control person of this entity.

Reporting person may be deemed a control person of this entity.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

One-third of the option vests on the first anniversary of issuance and 1/48th each month thereafter for 36 months.

Represents the weighted average purchase price. Actual purchase prices ranged from $35.98 to $36.05.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended.

The option vests on the date of the Company's 2026 annual meeting of stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan, as amended, and vests on the earlier of the one year anniversary of the grant date or the Issuer's 2026 Annual Meeting of Stockholders.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

The option was granted pursuant to the Issuer's Amended and Restated 2020 Stock Incentive Plan.

One-third of the option vests on the first anniversary of issuance and 1/36th each month thereafter for 24 months.

Involuntary sale of fractional shares following a reverse stock split of the Issuer's common stock.

Shares were surrendered without considerations following a reverse stock split of the Issuer's common stock.

Involuntary sale of fractional shares following a reverse stock split of the Issuer's common stock

Involuntary sale of fractional shares following a reverse stock split of the Issuer's comment stock.

Involuntary sale of fractional share following a reverse stock split of the Issuer's common stock.