6-K

SECURITIESAND EXCHANGE COMMISSION

Washington,D.C. 20549

FORM6-K

REPORTOF FOREIGN PRIVATE ISSUER

PURSUANTTO RULE 13a-16 OR 15d-163

UNDERTHE SECURITIES EXCHANGE ACT OF 1934

Forthe month of April 2025

AlterityTherapeutics Limited

(Name of Registrant)

Level 14, 350 Collins Street,Melbourne, Victoria 3000 Australia

(Address of Principal Executive Office)

Indicateby check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒       Form 40-F ☐

ThisForm 6-K is being incorporated by reference into our Registration Statement on Form S-8 (Files No. 333-251073, 333-248980and 333-228671) and ourRegistration Statements on Form F-3 (Files No. 333-274816, 333-251647, 333-231417and 333-250076)

ALTERITYTHERAPEUTICS LIMITED

(adevelopment stage enterprise)

The following exhibits are submitted:

1

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: April 22, 2025

2

Exhibit 99.1

As at Date: 16 - Apr - 2025 Top Holders Grouped Report Alterity Therapeutics Limited Security Class(es): ATHOPTWC25 - LISTED OPT EXP 26/02/2027 @ $0.028 Display Top: 20 ABN: 27 152 260 814 Level 5, 126 Phillip Street, Sydney NSW 2000 GPO Box 5193, Sydney NSW 2000 1300 288 664 (within australia) +61 2 9698 5414 (international) [email protected] www.automic.com.au % IC Holding Holder Name Position 29.25% 357,496,669 UBS NOMINEES PTY LTD 1 18.11% 221,393,841 CITICORP NOMINEES PTY LIMITED 2 7.81% 95,454,546 HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED 3 7.68% 93,856,318 BNP PARIBAS NOMS PTY LTD 4 6.04% 73,785,556 WARBONT NOMINEES PTY LTD <UNPAID ENTREPOT A/C> 5 6.02% 73,586,854 J P MORGAN NOMINEES AUSTRALIA PTY LIMITED 6 4.20% 51,320,761 BNP PARIBAS NOMS (NZ) LTD 7 2.76% 33,785,556 NEWECONOMY COM AU NOMINEES PTY LIMITED <900 ACCOUNT> 8 2.73% 33,333,334 HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED - GSCO ECA 9 2.48% 30,303,031 ORCHIDBAY INVESTMENTS PTY LTD <ORCHIDBAY INVESTMENTS A/C> 10 2.25% 27,450,403 MERRILL LYNCH (AUSTRALIA) NOMINEES PTY LIMITED 11 2.19% 26,810,350 HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED - A/C 2 12 1.86% 22,727,273 JAGEN NOMINEES PTY LTD <THE B LIBERMAN FAMILY A/C> 13

Report generated on 16 - Apr - 2025 at 09:54 AM ABN: 27 152 260 814 Level 5, 126 Phillip Street, Sydney NSW 2000 GPO Box 5193, Sydney NSW 2000 1300 288 664 (within australia) +61 2 9698 5414 (international) [email protected] www.automic.com.au Position Holder Name Holding % IC 1.36% 16,666,667 BILGOLA NOMINEES PTY LIMITED 14 0.66% 8,060,606 KYRIACO BARBER PTY LTD 15 0.62% 7,575,758 JL FAMILY NOMINEES PTY LTD <JUSTIN LIBERMAN FAMILY A/C> 16 0.55% 6,666,667 BNP PARIBAS NOMS PTY LTD <GLOBAL MARKETS> 17 0.50% 6,060,606 ONE MANAGED INVESTMENT FUNDS LIMITED <TI GROWTH A/C> 18 0.43% 5,303,031 NETWEALTH INVESTMENTS LIMITED <WRAP SERVICES A/C> 19 0.40% 4,841,797 HEDGEFUN MANAGERS PTY LTD 20 97.89% 1,196,479,624 TOTALS 100.00% 1,222,300,911 Total Issued Capital

As at Date: 16 - Apr - 2025 Holdings Range Report Alterity Therapeutics Limited Security Class(es): ATHOPTWC25 - LISTED OPT EXP 26/02/2027 @ $0.028 Report generated on 16 - Apr - 2025 at 09:55 AM ABN: 27 152 260 814 Level 5, 126 Phillip Street, Sydney NSW 2000 GPO Box 5193, Sydney NSW 2000 1300 288 664 (within australia) +61 2 9698 5414 (international) [email protected] www.automic.com.au 0.00% 0 0 above 0 up to and including 1,000 0.00% 0 0 above 1,000 up to and including 5,000 0.00% 0 0 above 5,000 up to and including 10,000 0.18% 2,155,000 25 above 10,000 up to and including 100,000 99.82% 1,220,145,911 46 above 100,000 100.00% 1,222,300,911 71 TOTALS Holding Ranges Holders Total Units % Issued Share Capital