6-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Form 6-K

Report ofForeign Issuer

Pursuant to Section 13a-16 or15d-16

of the Securities Exchange Act of 1934

For the month of: January, 2022

Commission File Number: 001-38336

NUTRIEN LTD.

(Name ofregistrant)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Form 20-F  ☐            Form 40-F  ☒

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):  ☐

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):  ☐

Exhibit 99.1 to this report on Form 6-K shall be incorporated by reference into and as an exhibit to the registrant’s Registration Statements on Form S-8 (File Nos. 333-222384, 333-222385 and 333-226295) and on Form F-10 (File No. 333-237068) under the Securities Act of 1933, as amended.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

EXHIBIT INDEX

EX-99.1

Exhibit 99.1

FORM 51-102F3

MATERIAL CHANGE REPORT

Nutrien Ltd. (“Nutrien”)

122 - 1st Avenue South, Suite 500

Saskatoon, Saskatchewan, S7K 7G3

January 4, 2022

A news release disclosing the material change was issued by Nutrien on January 4, 2022 and disseminated through the facilities of Business Wire. A copy of the news release was filed on SEDAR with the securities regulatory authorities in each of the provinces of Canada.

On January 4, 2022, Nutrien announced that Mr. Mayo Schmidt has left his position as President and Chief Executive Officer of Nutrien and has resigned from the board of directors of Nutrien (the “Board”). Mr. Ken Seitz, Executive Vice President and Chief Executive Officer of Potash, has been named Nutrien’s interim President and Chief Executive Officer.

On January 4, 2022, Nutrien announced that Mr. Schmidt has left his position as President and Chief Executive Officer of Nutrien and has resigned from the Board.

Mr. Seitz, Executive Vice President and Chief Executive Officer of Potash, has been named Nutrien’s interim President and Chief Executive Officer. Mr. Seitz joined Nutrien as Executive Vice President and Chief Executive Officer of Potash in 2019 and previously served as President and Chief Executive Officer of Canpotex Limited, a potash exporter.

Nutrien also announced that the Board will be working with an executive search firm to begin a global search to select a permanent Chief Executive Officer, which will consider internal and external candidates.

Not applicable.

Not applicable.

Not applicable.

For further information, please contact Michael Webb, Executive Vice President and Chief Human Resources and Administrative Officer, at (403) 225-7000.

January 13, 2022

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