Good morning, and welcome to Oncolytics Biotech's Second Quarter 2023 Conference Call. All participants are now in listen-only mode. There will be a question-and-answer session at the end of this call. Please be advised that this call is being recorded at the company's request. I would now like to turn the call over to Jon Patton, Director of Investor Relations and Communications. Please go ahead.

Thank you, operator, and good morning, everyone. Earlier this morning, Oncolytics issued a press release providing recent operational highlights and financial results for the second quarter of 2023. A replay of today's call will be available on the Events & Presentations section of the Oncolytics website approximately two hours after its completion. After remarks from company management, we will open the call for Q&A. As a reminder, various remarks made during this call contain certain forward-looking statements relating to the company's business prospects and the development and commercialization of pelareorep, including statements regarding the company's focus, strategy and objectives, company's belief as to the potential and mode of action of pelareorep as a cancer therapeutic, company's plans regarding Precision Promise and the anticipated timing of entering into a definitive agreement in connection therewith, the company's plans and expectations regarding potential and registrational studies, the company's business development plans and strategies, and other statements related to anticipated developments in the company's business. These statements are based on management's current expectations and beliefs and are subject to a number of factors, which involve known and unknown risks, delays, uncertainties and other factors not under the company's control that may cause actual results, performance or achievements of the company to be materially different from the results, performance or expectations implied by these forward-looking statements. Any new forward-looking statement in which Oncolytics expresses an expectation or beliefs as to future results, such expectations or beliefs are expressed in good faith and are believed to have a reasonable basis, but there can be no assurance that these statements or expectations or beliefs will be achieved. These factors include results of current or pending clinical trials, risks associated with intellectual property protection, financial projections, actions by regulatory agencies and those factors detailed in the company's filings with the SEDAR and the SEC. Oncolytics does not undertake any obligation to update these forward-looking statements, except as required by applicable laws. On our call today we hear from Oncolytics' Chief Executive Officer, Dr. Matt Coffey; Chief Medical Officer, Dr. Thomas Heineman; Global Head of Business Development, Andrew de Guttadauro; and Chief Financial Officer, Kirk Look. I'll now hand the call off to Matt to give a few highlights from this past quarter. Matt?

Thank you Jon, and welcome to all who have joined us this morning. We are excited by the continued progress of our CAR T programs for pelareorep, or pela, as we will refer to it in pancreatic and breast cancer that are being accelerated towards registrational studies. In June at the ASCO annual meeting, we presented results from our HR positive, HER-2 negative metastatic breast cancer program. Data from the randomized BRACELET-1 trial showed a 50% improvement in progression-free survival and a nearly threefold increase in confirmed overall response rate for pela in combination with paclitaxel versus paclitaxel alone. This impressive data readout validated earlier Phase 2 results from IND-213, which showed a statistically significant near doubling of median overall survival in HR positive HER-2 negative metastatic breast cancer patients. This program is now Phase 3 ready. The company will now prioritize progressing swiftly to a registrational trial of pela-paclitaxel combination therapy in HR positive HER-2 negative metastatic breast cancer. Our second registration program in pancreatic cancer has generated compelling data and is clearly attracting attention among thought leaders in the community. This is evidenced by pela being selected as a new investigational treatment in Precision Promise, an innovative adaptive Phase 3 clinical trial designed to accelerate registration pathways for pancreatic cancer therapies and expected to reduce Phase 3 costs by about 50% compared to a traditional trial. The study's success is expected to support approval of pela in combination with the checkpoint inhibitor and the chemotherapeutic agents gemcitabine and nab-paclitaxel for the treatment of first-line metastatic pancreatic ductal adenocarcinoma. Pela's inclusion in Precision Promise is supported by prior pancreatic cancer clinical data that suggests it synergizes with checkpoint inhibition and chemotherapy. As a reminder, our Phase 1/2 GOBLET study data has almost tripled the average historical objective response rate by combining pela with nab-paclitaxel, gemcitabine and atezolizumab in first-line advanced pancreatic cancer. However, in total we have data from over 120 pancreatic cancer patients. We have treated across multiple studies with and without chemotherapy and checkpoint inhibitors, which Tom will discuss a bit later. Our plan for this indication is to finalize agreements with the Precision Promise team by the fourth quarter of this year, and we expect to open the investigational treatment of pela, a checkpoint inhibitor, gemcitabine, and nab-paclitaxel in early 2024. At the end of July, we announced a $15 million equity offering, which closed last week and was led by a healthcare-focused institutional investor. Our HR positive HER-2 negative metastatic breast cancer and metastatic pancreatic cancer programs both represent meaningful registration opportunities, and this additional funding further strengthens our position to advance pela into registrational trials. We plan to provide guidance on the registration enabling pathway for both of these programs later this year. Now, I'll turn the call over to Tom and Andrew for a more detailed discussion of our clinical programs and business development efforts. We'll start with you, Tom.

Thanks Matt. I'll begin my section by summarizing and highlighting the key data from our two pillar programs. As Matt mentioned, we are thrilled with the readout from our randomized BRACELET-1 trial of pela combined with paclitaxel and HR positive HER-2 negative metastatic breast cancer. These data showed that pela combination therapy led to a robust improvement in progression-free survival with a hazard ratio of 0.29 and a nearly threefold increase in the confirmed overall response rate. Just to emphasize, a hazard ratio of 0.29 means that a combination of pela and paclitaxel reduced the risk of disease progression by 71% compared to paclitaxel monotherapy. We hosted a key opinion leader webinar on June 5th to provide expert perspectives on these results and what they mean for our HR positive HER-2 negative breast cancer programs' next steps. If you missed the webinar and are interested in a more detailed discussion of the BRACELET-1 results, we encourage you to watch the replay that is available in the Events & Presentations section of our company website. As a reminder, BRACELET-1 is a randomized Phase 2 trial that enrolled a total of 48 HR positive HER-2 negative metastatic breast cancer patients into three groups. The control group that received paclitaxel monotherapy, a group that received the combination of paclitaxel and pela, and a third group that received paclitaxel-pela, and the checkpoint inhibitor avelumab. The BRACELET-1 primary endpoint was overall response rate at week 16 with additional endpoints of progression-free survival, safety, and tolerability, and immune biomarker evaluation. The BRACELET-1 primary endpoint of overall response rate at week 16 increased from 20% in the paclitaxel monotherapy arm to 31% in the paclitaxel-pela combination arm. The benefit of adding pela to paclitaxel became even more apparent as the data matured with a 37.5% confirmed overall response rate in the pela-paclitaxel combination arm compared to only 13% for paclitaxel monotherapy. Adding avelumab to paclitaxel and pela did not improve anti-cancer activity, which reinforces our decision to focus on the pela-paclitaxel doublet as we move forward to our registrational study. BRACELET-1 also includes an endpoint of progression-free survival, which has been used to support approvals of oncology drugs, including in breast cancer. We observed a robust increase in progression-free survival in the pela plus paclitaxel cohort compared to the control arm. Median progression-free survival was 6.3 months in the paclitaxel monotherapy group and increased by more than 50% to 9.5 months in the pela-paclitaxel combination group for a hazard ratio of 0.29 as of a March 2023 data cutoff. While the study was not designed for statistical comparisons, the progression-free survival benefit in the pela plus paclitaxel arm reached statistical significance. The addition of avelumab to the pela-paclitaxel combination did not add clinical benefit. In fact, the avelumab combination behaved similarly to paclitaxel monotherapy, suggesting that the addition of avelumab actually nullified the beneficial effects of pela. The question of why adding avelumab may have reversed the beneficial effects of the pela-paclitaxel combination therapy was discussed during our key opinion leader webinar on June 5th. Briefly, avelumab is unique among licensed checkpoint inhibitors in its ability to bind FC receptors, including those on immune cells. This may have led to the eradication of potentially protective pela-induced immune responses. Translational data from the BRACELET-1 study support this hypothesis. It's important to note that overall survival results from BRACELET-1 have not been reported yet as multiple patients continue to be followed for survival. BRACELET-1 is the second randomized Phase 2 study in which pela combined with paclitaxel provided clinical benefit in patients with metastatic breast cancer. Specifically, these data support the findings from the earlier IND-213 study in which pela plus paclitaxel demonstrated a statistically significant near doubling of median overall survival in HR positive HER-2 negative metastatic breast cancer patients. These two trials taken together provide a strong foundation for a registrational study with dual primary endpoints of overall survival and progression-free survival. Incorporating progression-free survival as an endpoint offers the potential to deliver a key data readout substantially earlier than would be possible with a single primary endpoint of overall survival. Based on the findings from IND-213 and BRACELET-1, we can now confidently move to a registrational study in HR positive HER-2 negative metastatic breast cancer. Next, I'd like to switch to a discussion of our pancreatic cancer program. Our Phase 1/2 GOBLET trial in which patients are treated with pela plus Roche's checkpoint inhibitor atezolizumab is evaluating multiple gastrointestinal cancers and continues to make encouraging progress towards key milestones, especially in the pancreatic cancer cohort, which forms our pipeline's second core pillar. As Matt mentioned, we are very excited that pela combination therapy has been selected by a panel of pancreatic cancer experts as a new investigational treatment arm in the pivotal Precision Promise Phase 3 platform trial. The Precision Promise trial is designed to accelerate the development of promising new therapies for metastatic pancreatic cancer. The trial was designed with guidance from the FDA and optimizes the number of participants needed to generate licensure enabling data. This, along with operational efficiencies, can accelerate late-stage development by up to two years compared to traditional registrational trials. The inclusion of pela-based combination therapy in the Precision Promise trial is based on data from our prior pancreatic cancer clinical studies that support pela's ability to synergize with checkpoint inhibition and chemotherapy to benefit patients with metastatic pancreatic cancer. Prior data include preliminary results from our Phase 1/2 GOBLET study that showed a 69% objective response rate in first-line advanced or metastatic pancreatic cancer patients treated with pela combined with atezolizumab and standard-of-care chemotherapy, gemcitabine and nab-paclitaxel. This compares to an average of about 25% objective response rate observed in historical trials in metastatic pancreatic cancer. While the GOBLET study is our most recent pancreatic cancer trials, we also have data from several prior studies in this disease and have treated over 120 pancreatic cancer patients with pela-based combination therapies. The previous studies laid the foundation for the GOBLET study as they suggested that pela-based combination therapies could provide favorable outcomes in pancreatic cancer patients. These included improved overall survival, as well as potentially beneficial immunologic effects, including the stimulation of adaptive immune responses and an influx of CD8+ T cells into the tumors. Looking forward, we anticipate providing updated data from the GOBLET pancreatic cancer cohort, as well as updates from the advanced anal and metastatic colorectal cancer cohorts in the second half of the year. We'll also provide additional guidance on the path towards registration in pancreatic cancer later this year.

Thank you, Tom and good morning, everyone. From a BD perspective, the top line data readout from our BRACELET-1 trial was the featured headline of the quarter. As the BRACELET-1 data mature and we integrate data that we've already generated from IND-213 and the WEAR-1, we'll be able to better leverage the full suite of immunotherapeutic effects of pela in breast cancer. As we move towards registration, we plan to pursue the most advantageous global clinical and commercialization partnership. We have already established several relationships with leading biopharma companies like Pfizer, Roche, Merck Serono, and others. This initial interest came from our previously reported IND-213 study, which demonstrated a statistically significant near doubling of median overall survival in HR positive HER-2 negative metastatic breast cancer patients, the same population that was treated in BRACELET-1. Having seen the BRACELET-1 study data made public in June at ASCO, additional biopharma companies have come forward and we have just begun meaningful discussions with certain potential new collaborators. While it is too soon to speculate on a potential deal at this juncture, it has been encouraging to have an uptick in interest from the biopharma community. We plan to foster these relationships to generate competitive tension between potential partners to ensure we reach the optimal deal for the future of pela and our shareholders at the right time. On the pancreatic cancer front, we reported interim data from the GOBLET study in November of last year, and we announced we received fast-track designation from the FDA in December. The effect of these news events are still being felt in the Precision Promise announcement Tom discussed. What some people may not realize is that the vetting process for pelareorep to be included in the Precision Promise platform trial was quite rigorous. We had meetings and presentations with multiple pancreatic cancer key opinion leaders over the course of several months where they reviewed the GOBLET data, but also multiple historical pancreatic cancer studies that in aggregate have included over 120 pelareorep patients. We were very pleased to have been selected for this Phase 3 opportunity and we look forward to a productive relationship to bring better treatment options to pancreatic cancer patients. We also continue to be excited by the preclinical CAR T results presented at ASCO and in Science Translational Medicine. CAR T therapies generated more than $1 billion in sales last year in a subset of cancer patients with hematological malignancies. The potential for pela to enable CAR T therapies in solid tumor indications represents an opportunity for us to expand what is an already large market and solid tumors are the vast majority of the cancers diagnosed each year. Our strategy is to engage potential partners with the goal of out-licensing pela's development as an enabling technology for CAR T therapies, which would allow us to participate in the lucrative upside potential CAR T commercial opportunity with minimal risk and a continued focus on our current core clinical programs in breast and pancreatic cancer. The impressive and growing safety database for pela, combined with numerous leading anti-cancer agents without causing unacceptable toxicities, has been exhibited across many combinations and indications. This supports the case for continued development of pela as an immunotherapy backbone that can enhance the efficacy of other agents and continues to be a strong selling point in our conversations with potential partners who are interested in harnessing its immunologic effects to maximize the commercial impact of their own drugs and therapeutic candidates. Next, I'll hand it to Kirk to discuss our recent financial results.

Thank you, Andrew. I'm pleased to report that Oncolytics continues to improve its financial position. As Matt mentioned at the start of our call, we successfully raised $15 million in a public offering led by a healthcare-focused institutional investor. These funds, along with our existing resources, allow us to move forward with the definitive agreements for the Precision Promise study and obtain the necessary regulatory approval to start enrollment. With the ASCO BRACELET-1 data in hand, we can continue to move forward with the regulatory process seeking FDA advice and guidance on a registrational study in HR positive HER-2 negative metastatic breast cancer. As of June 30th, 2023, we had $24.4 million in cash, cash equivalents and marketable securities compared to $32.1 million as of December 31st, 2022. After the close of our recently announced public offering, our pro forma cash balance stands at $42.7 million and our anticipated financial runway now extends towards the end of 2024. Our general and administrative expenses for the second quarter of 2023 were $3.5 million compared to $2.8 million for the same period last year. The increase is primarily due to higher investor relations activities and a rise in costs associated with our annual general meeting. Research and development expenses for the second quarter of 2023 were $3.7 million compared to $3.2 million for the same period last year. The increase comes from higher manufacturing and personnel-related expenses, partly offset by lower BRACELET-1 study costs. The net loss for the second quarter of 2023 was $7.4 million compared to $5.1 million in the second quarter of 2022. This equates to a net loss of $0.12 per share for the second quarter of 2023 and $0.09 per share for the second quarter of 2022. This completes my financial review and brings us to Matt's closing remarks.

Thanks Kirk. Now before moving to the Q&A, I'll provide a brief recap of all the exciting milestones we expect to achieve by the end of the year. We plan to provide updates at ESMO in the second half of the year from GOBLET patients in our first-line pancreatic cancer cohort and third-line metastatic colorectal cancer cohort. We also anticipate providing additional guidance on the registrational pathway for both of our CAR T programs in pancreatic cancer and HR positive HER-2 negative metastatic breast cancer. The BRACELET-1 overall survival data continues to mature, so we'll provide an update on that timeline once we can provide a reasonable expectation. As always, I would like to express my gratitude for all the contributions from our collaborators, talented employees, dedicated investigators to patients participating in our studies, and of course, all of our investors. We'll now open the call up for questions. Operator?

Thank you, sir. And your first question will be from Patrick Trucchio at H.C. Wainwright. Please go ahead.

Thanks. Good morning, and congrats on all the progress. I guess, just a couple of questions from me. The first is, can you talk a little bit about the pace of enrollment in the Precision Promise program and specifically, how much influence will you have on the conduct of this program, and how is it expected to accelerate the registrational pathway for pelareorep? And then, secondly, also regarding this program, what would you expect to be necessary to lead to an accelerated approval pathway in pancreatic, and when might you have that first data cut from the program?

Thanks Patrick. That's a great question. Tom and Andrew are probably closest to this. So, I'll let Tom talk to the regulatory acceleration and the benefits of working in this. And I think Andrew might want to weigh in a little bit on what their presumed timelines are based on the enrollment assumptions that they've made public. Tom, do you want to kick us off a little bit?

Sure. The benefits of collaborating with Precision Promise extend beyond cost considerations. One key advantage is that the Precision Promise protocol is a well-established study that has been thoroughly reviewed and discussed with the FDA. This gives us a solid clinical program and pathway. The study is already partnered with many top academic sites in the U.S., providing us access to numerous experts in pancreatic cancer who are highly experienced not just in the disease, but specifically in this study. Consequently, we have a reliable group of partners to work with right from the start, which will facilitate enrollment and help address any issues that may arise during the study. From a regulatory standpoint, as mentioned, this study was already developed in collaboration with the FDA. If all goes well and we achieve the expected positive outcomes, there should be a clear route to a BLA submission based on this study's results without needing to conduct additional studies afterward. These are some of the advantages of working with them. Additionally, the operational benefits include time savings, as we won't need to initiate sites or familiarize everyone with the protocol. Thus, we see clear operational efficiencies alongside the regulatory benefits and access to highly qualified experts in the field.

Yeah. Helpful.

Andrew, can you talk a little bit on the number of sites and then anticipated enrollment? I think we're targeting what, 18 months after the time of initiation for that first read?

Yeah. About that. We expect we'll sign the agreement in the next couple of months, hopefully somewhere around there. And then it's about 17 months to get to go/no-go analysis. So, figure around the first half of 2025, we'd have that initial read, Patrick. Because the speed is much faster than if we had to start this organically, as Tom was saying, where you have to start every site. In terms of number of sites, there are 28 sites. What's unique about the sites is they're all brand name, top sites with some of the most famous pancreatic key opinion leaders in the industry. You're talking about places like MD Anderson, Memorial Sloan Kettering, and the like. So, they can recruit fast because that's where patients are referred to for something as intractable as pancreatic. So, they've given us their projections. We're pretty positive that we can get to that go/no-go decision around the first half of 2025, assuming everything moves forward as planned with the execution of the definitive agreements and other paperwork that needs to be put in place, and that's already ongoing as we speak.

Right. Got it. That's really helpful. And I'm wondering if you can discuss further some of the preclinical research collaboration evaluating pela plus CAR T combination and when you might have further details to present.

That's a great question. So, we do have companies we've been public about, without naming whom, who are testing our pelareorep with their CAR Ts because we believe that largely, for instance, with PD-1/L1s, we work pretty well with all of them, with the exception of one that had that FC portion discrepancy. That's not the case with CAR Ts. CAR Ts, as you know, are very particular both to the antigen, their construct, how they're made, and what they target. We really have to go one by one with companies that are interested and have our pela tested with their constructs. So far the results have been promising, but I don't know yet when those will be presented because a lot of that is dependent on the type of agreement and how willing the company may be to share those results publicly quickly, especially if it confers a potential advantage in moving forward. But certainly before anything moves into the clinic, they would have to sign a definitive licensing agreement with us to allow them to do that work. At that point, we would make something more public for sure.

Great. Thank you very much.

Thank you. Next question will be from Soumit Roy at Jones Research. Please go ahead.

Good morning, everyone, and congratulations on all the progress. Regarding breast cancer, I’d like to understand how strict the enrollment criteria were for the HER-2 negative patients. Were there any HER-2 low patients considered before the recent acknowledgment of HER-2 low being effective against HER-2 therapies? I’m trying to determine how strict the enrollment criteria were and what went well with your 15 and 16 patients in each trial arm that gives you the confidence to maintain that kind of enrollment criteria in the registration trial to ensure continued success.

Great question. Tom, do you want to jump in and talk about sort of the evolving HER-2 status and what that means potentially going forward and why we're so confident that this study is replicating what we're seeing with IND-213?

Sure. When this study was conducted, the idea of HER-2 low as a marker for specific therapy was not established yet. Antibody drug conjugates had not been approved. I'm quite sure that both HER-2 negative and HER-2 low patients were included in this study as would be expected. The reason we are confident in the data from this study is that these patients had already failed standard-of-care hormonal therapy, including those treated with CDK 4/6 inhibitors. This group is typical of patients with metastatic breast cancer who are now ready for chemotherapy. We observed a strong objective response rate and progression-free survival benefit. These patients will continue to exist in the real world, even with the availability of antibody drug conjugates, because some patients may not qualify for those therapies and will need alternatives. Additionally, there will be patients who do receive antibody drug conjugates but subsequently fail those treatments; as effective as they are, they do not offer a cure. Once such patients progress after receiving antibody drug conjugates, they will also require new treatment options. We believe that the pela-based combination will be a potentially beneficial treatment for both patients ineligible for antibody drug conjugates and those who eventually fail this therapy.

So for the registration trial, how would you set up the enrollment criteria? Would you make it strictly as HER-2 negatives or would you be more amenable depending on the physician's choice if they're ready?

Well, this is a matter for ongoing discussion, including ultimately with the FDA, but I think we can pretty confidently say that there is a medical population with a substantial medical need that we can define in the Phase 3 population. Whether the exact details need to be worked out, but it's likely to include, for example, patients who have failed antibody drug conjugate therapy, plus or minus perhaps those patients who are ineligible for antibody drug conjugate. There are plenty of patients out there who are going to need options and I don't think we'll have any trouble defining a population in Phase 3 that can address that need.

Thank you for the information. I have one last question. When can we expect an update on the registration trial for breast cancer? Will it be around the end of the year? Also, regarding the pancreatic cancer trial, do we know what the primary endpoint is? Is it progression-free survival or overall survival?

Yeah. I mean, for the pancreatic cancer trial, the primary endpoint will be overall survival, right, as is typical in pancreatic cancer studies. Perhaps I'll have Matt comment on the update on the breast cancer.

Yeah. Soumit, we're letting the OS actually develop, just to ensure that we have the likelihood of a dual endpoint. We're still actually tracing or tracking patients who are just receiving paclitaxel plus pela. We haven't even got to the full PFS on that, which is fascinating because arm one, we didn't even get anyone out to like 12 months and we know we have patients out at cycle 2022, 2023 now. What we sort of suspect will happen is we're in discussions with a number of groups, as Tom alluded to. We think it's probably easiest to capture this population in the post ADAC. Patients would go from a CDK 4/6 to a first-line ADAC. We're just seeing people get onto first-line ADACs now. We do anticipate after San Antonio, there'll be more of these patients. We're thinking a sufficient pool of patients will be available mid-next year. In terms of regulatory filings, we will be reaching out to the agency this year, so we're hoping for the ability to provide some regulatory guidance late this year, early next as the OS matures. Some of this, of course, is just scheduling with the FDA and the parties we're talking to who have vested interest in the ADACs would obviously like us to not cannibalize those sales, but rather be a creative to them by just tracking the same patients that are going to be able to receive the HR lows. As I'm sure you know, at ASCO, there's literature now saying you can test a patient, have them be negative, test them again, and they'll be slightly positive. The whole concept around what is an HR negative patient, I think is in flux. By doing our regulatory filings this year, we'll have more color around what the true nature of the patient population is, but as Tom said, there's no shortage of these patients. We're very confident we'll get to a definable patient population that stakeholders and the FDA can agree with.

All right. Thank you so much again for all the color and taking the questions. We look forward to the ESMO data.

Thanks so much.

Thank you. Your next question will be from John Newman at Canaccord. Please go ahead.

Hi, guys. Good morning, and thanks for taking my question. So, Matt, just had a kind of a follow-up question on the ADCs. How do you think about pelareorep, excuse me, being used long-term with ADCs? Do you see a pathway here where perhaps you get your initial approval in combination with chemotherapy, but then you're able to perhaps investigate a combination with ADCs? And if so, is there a specific subset of patients that you think might be more attractive for that combination? Thanks.

Yeah. No, absolutely. So, the first part of your question is what we would look to do is go after ADAC failures who are still taxane-naive. Similar to the patient population that we treated on BRACELET, in terms that they would be taxane-naive. We don't think that ADACs are especially immunosuppressive. They're actually deemed to be quite mild, in comparison to chemotherapy. We don't think this would diminish the immunological response. In terms of ultimately combining with ADACs, we are very interested in that possibility. What we know of our agent is that anything that causes cellular stress does lead to susceptibility. We're seeing that the product does seem to work better in patients that have better immunological status or basically just saying it works better in patients who aren't as heavily pretreated. We do think that there is a role for combining this with ADAC that would be part of our lifecycle management, and it is something that stakeholders have actively asked us to pursue. So, it is obviously an area of interest for us.

Thank you. And at this time, gentlemen, it appears that we have no other questions. Please proceed with any closing remarks.

Well, thank you operator, and thanks to all who joined our call today. Have a great day. Thanks very much.

Thank you, sir. Ladies and gentlemen, this does indeed conclude your conference call for today. Once again, thank you for attending. And at this time we do ask that you please disconnect your lines.