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SLNO · Soleno Therapeutics Inc

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Market Cap
$2.76B
Shares
52.12M

No Price Data

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FQ3-26 quarter ends
~Sep 30, 2026 Est
filed May 7, 2026

AI Brief

TL;DR.

Bullish
    Bearish

      AI-generated from the earnings call and 8-K · may contain errors · not investment advice

      Ask ALVIS about this →

      Equibles Rating

      blended score · not investment advice
      Overall
      Buy
      SellHoldBuy
      Technical Limited Momentum Limited Sentiment Neutral Fundamentals Excellent Quant / Vol Limited
      Market backdrop VIX 14.3 · calm Equity put/call 0.52
      Technical
      price trend
      Limited
      Not enough data for a confident read.
      Momentum
      relative strength
      Limited
      Not enough data for a confident read.
      Sentiment
      smart money
      Neutral
      Trend (MA cross) No cross
      50/200-day averages unavailable
      Institutional flow Distributing
      -10% holders QoQ · +44 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Falling
      8.45% of float · ▼ -32.5% MoM · 2.3 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Steady
      228 holders — mid 3-yr range
      Fundamentals
      Excellent
      Revenue growth +139%
      Y/Y
      Gross margin -4%
      contracting
      EPS growth +109%
      Y/Y
      Free cash flow $46.7M
      Buyback $100.0M
      authorized
      Balance sheet $20.2M
      net cash
      Quant / Vol
      risk profile
      Limited
      Not enough data for a confident read.

      Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

      Key metrics

      the company's own KPIs, from written earnings releases and filings
      Metric Latest Period YoY
      active patients on drug 859 as of December 31, 2025
      cash flow from operating activities $48.7M the fourth quarter
      invested in accelerated share repurchase program $100M the year ended December 31, 2025
      lives covered 185M from approval on March 26, 2025 through December 31, 2025
      new prescribers in the fourth quarter 136 the fourth quarter
      patient start forms received 1,250 from approval on March 26, 2025 through December 31, 2025
      patient start forms received (fourth quarter) 207 the fourth quarter
      unique prescribers 630 from approval on March 26, 2025 through December 31, 2025
      Discontinuation rate of VYKAT XR related to adverse events 12% fourth quarter 2025
      Lives covered as percentage of total lives 60% from launch through December 31, 2025

      Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

      Versus peers

      Biotechnology — same industry group
      Open screener →
      Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
      SLNO
      Soleno Therapeutics Inc
      this stock
      $2.76B +138.8% 8.5%
      ONC
      BeOne Medicines Ltd.
      $513.62B +14.4% +22179.2% 789.7 0.1%
      VRTX
      Vertex Pharmaceuticals Inc / Ma
      $128.19B +11.6% +46.2% 29.5 1.6%
      REGN
      Regeneron Pharmaceuticals, Inc.
      $82.72B +4.1% +20.8% 19.9 3.3%
      ARGX
      Argenx SE
      $52.94B +1.2% 2.1%

      Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

      At a glance

      key data from every section
      Ownership
      Institutional Holders Reducing
      Holders
      228
      % held
      126.6%
      Net QoQ
      -2.4M sh
      Top holder
      JANUS HENDERSON GROUP PLC
      Held Float
      View
      Held by Funds
      Fund positions
      165
      View
      Short & Settlement
      Short Interest Falling
      Shares short
      4.4M
      Days to cover
      2.3d
      Change
      -2.1M sh
      View
      Short Volume
      Short vol %
      31%
      As of
      May 15, 2026
      Short Total
      View
      Fails to Deliver
      FTD shares
      201
      Value
      $10.7K
      As of
      May 20, 2026
      View
      Financials
      Financials
      Revenue (FY)
      $1.5M
      Net income (FY)
      $20.9M
      EPS diluted
      $0.39
      View
      Buybacks
      Authorized
      $100.0M
      View
      Filings
      SEC Filings
      Latest
      8-K
      Filed
      May 18, 2026
      This year
      12
      View
      Proposed Sales
      Value
      $110.7M
      Shares
      1.3M
      Filed
      Aug 15, 2025
      View
      Exempt Offerings
      Offering
      $60.0M
      Filed
      Oct 4, 2023
      View
      Earnings & Events
      Earnings Calls
      Last call
      Mar 4, 2026
      View
      Key facts CIK 1484565 CUSIP 834203309 13F (30d) 3 filings 3 filers Visit website Investor relations