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ATHE 6-K

Alterity Therapeutics Ltd (ATHE)

6-K 2025-07-07 For: 2025-07-07
View Original
Added on April 09, 2026

SECURITIESAND EXCHANGE COMMISSION

Washington,D.C. 20549

FORM6-K

REPORTOF FOREIGN PRIVATE ISSUER

PURSUANTTO RULE 13a-16 OR 15d-163

UNDERTHE SECURITIES EXCHANGE ACT OF 1934


Forthe month of July 2025

AlterityTherapeutics Limited

(Name of Registrant)

Level 14, 350 Collins Street,Melbourne, Victoria 3000 Australia

(Address of Principal Executive Office)

Indicateby check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.


Form 20-F ☒       Form 40-F ☐


ThisForm 6-K is being incorporated by reference into our Registration Statement on Form S-8 (Files No. 333-251073, 333-248980and 333-228671) and ourRegistration Statements on Form F-3 (Files No. 333-274816, 333-251647, 333-231417and 333-250076)

ALTERITYTHERAPEUTICS LIMITED

(adevelopment stage enterprise)

The following exhibits are submitted:

99.1 Change in substantial holding
1

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Alterity Therapeutics Limited
By: /s/ Geoffrey P. Kempler
Geoffrey P. Kempler
Chairman

Date: July 7, 2025

2

Exhibit 99.1

604    Page 1 of 2    15 July 2001

Form 604


Corporations Act 2001

Section671B


Notice of change of interests of substantial holder

To Company Name/Scheme AlterityTherapeutics Limited
ACN/ARSN 080699 065

1.Details of substantial holder (1)

Name The<br> Bank of New York Mellon Corporation (BNYMC) and each Group Entity listed in Annexure A (Group<br> Entity), (together BNYMC Group)
ACN/ARSN (if<br> applicable)
There was a change in the interests of the substantial holder on 03/July/2025
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The previous notice was given to the company on 22/May/2025
The previous notice was dated 21/May/2025

Previous and present voting power


The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows:

Class of securities (4) Previous notice Present notice
Person’s votes Voting power (5) Person’s votes Voting power (5)
Ordinary shares 2,466,998,317 27.03% 2,559,017,317* 28.04%*
*See Note 1 in Annexure C

3. Changes in relevant interests


Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows:

Date of change Person whose relevant interest changed Nature of change (6) Consideration given in relation to change (7) Class and number of securities affected Person’s votes affected
See Annexure B

4. Present relevant interests


Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows:

Holder of relevant interest Registered holder of securities Person entitled to be registered as holder (8) Nature of relevant<br><br> interest (6) Class and number of securities Person’s votes
See AnnexureC

604    Page 2 of 2    15 July 2001

5. Changes in association


The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows:

Name and ACN/ARSN (if applicable) Nature of association
BNYMC and each Group Entity Each Group Entity is an associate of BNYMC pursuant to section 12(2)(a) of the Corporations Act 2001 (Cth) as each entity is directly or indirectly owned and controlled by BNYMC.

6. Addresses


The addresses of persons named in this form are as follows:

Name Address
The Bank of New York Mellon Corporation 240 Greenwich Street, New York, NY 10286 USA
Each Group Entity 240 Greenwich Street, New York, NY 10286 USA

Signature


print name Kevin Lockhart capacity Attorney-In-Fact
sign here /s/ Kevin Lockhart date 04/July/2025

AnnexureA


Thisis Annexure A of 1 page referred to in Form 604 Notice of Change

of Interests of Substantial Holder given by The Bank of New York

MellonCorporation and its related bodies corporate.


The Bank of New York Mellon Corporation is the ultimate parent company of a corporate group comprised of a large number of operating and holding companies. Details of the entities directly owned and controlled by The Bank of New York Mellon Corporation are listed below.

The Bank of New York Mellon
Pershing Group LLC
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Pershing LLC
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print name Kevin Lockhart capacity Attorney-In-Fact
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sign here /s/ Kevin Lockhart date 04/July/2025

Annexure B

This is Annexure B of 1 page referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate


Changes in relevant interests


Date of change Person whose relevant interest changed Nature of Change Consideration given in relation to change Class and number of securities affected (Ordinary Shares) Person’s votes affected
27-May-2025 The Bank of New York Mellon Deposit of securities N/A 9,600,000 9,600,000
2-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 2,659,200 2,659,200
11-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 21,5646000 21,564,600
12-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 3,000,000 3,000,000
13-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 1,800,000 1,800,000
17-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 7,087,200 7,087,200
20-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 9,000,000 9,000,000
24-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 13,500,000 13,500,000
26-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 1,200,000 1,200,000
27-Jun-2025 The Bank of New York Mellon Deposit of securities N/A 9,000,000 9,000,000
1-Jul-2025 The Bank of New York Mellon Deposit of securities N/A 7,608,000 7,608,000
2-Jul-2025 The Bank of New York Mellon Deposit of securities N/A 3,000,000 3,000,000
3-Jul-2025 The Bank of New York Mellon Deposit of securities N/A 3,000,000 3,000,000
Print Name - Kevin Lockhart Capacity - Attorney-In-Fact
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Sign Here /s/ Kevin Lockhart Date - 04 July 2025

Annexure C


This is Annexure C of 2 pages referred to in Form 604 Noticeof Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporatePresent relevant interests

Holder of relevant interest Nature of relevant interest Class and number of securities
The Bank of New York Mellon (BNYM) Remote Interest Held Under Deposit Agreement<br><br> <br>****<br><br> <br>Relevant interest under section 608(1)(c) of the<br> Corporations Act 2001 (Cth) arising from BNYM having the limited power to dispose of, or control the exercise of a power to dispose<br> of, securities deposited with or held by BNYM (or its custodian or agent) in its capacity as depositary administering an ADR program<br> for Alterity Therapeutics Limited (Company) under the Deposit Agreement dated January 2, 2008 between the Company, holders<br> of American depositary receipts (ADRs) and BNYM (Deposit Agreement).<br><br> <br>[*See Note 1 below]. 2,559,016,348<br><br> <br>ordinary shares
BNYMC Group (other than BNYM) Relevant interest under section 608(3)(a) and/or section 608(3)(b) of the Corporations Act 2001 (Cth) being a relevant interest held through a body corporate (namely BNYM) in which the voting power of each other entity in the BNYMC Group is above 20%, or that each other entityin the BNYMC Group controls.<br><br> <br>[*See Note 1 and Note 2 below] 2,559,016,348<br><br> <br>ordinary shares
Pershing LLC Relevant interest under sections 608(1) of the Corporations Act 2001 (Cth) arising from Pershing LLC being the registered owner of the<br>securities. 969 ordinary shares
BNYMC Group (other than Pershing LLC) Relevant interest under section 608(3)(a) and/or section 608(3)(b) of the Corporations Act 2001 (Cth) being a relevant interest held through<br>a body corporate (namely Pershing LLC) in which the voting power of each other entity in the BNYMC Group is above 20%, or that each other<br>entity in the BNYMC Group controls.<br><br> <br>[*See Note 2 below] 969 ordinary shares

NOTES:

* Note 1:<br> Of the total of 2,559,017,317 securities in which the BNYMC Group has a relevant interest,<br> BNYM has a relevant interest in 2,559,016,348 securities as depositary for Alterity Therapeutics Limited ADR program administered under the Deposit Agreement. BNYM's relevant<br> interest in these securities arises as a result of the Deposit Agreement containing rights<br> for BNYM to dispose of securities held under the ADR program in limited circumstances. Under<br> the Deposit Agreement, ADR holders retain their rights to dispose of those securities and<br> to give voting instructions for the exercise of voting rights attached to the securities.<br> BNYMC Group's power to vote or dispose of these securities is qualified accordingly.
* Note 2: Each Group Entity is a direct<br> or indirect wholly owned subsidiary of BNYMC, the ultimate parent company. Other than BNYM<br> in respect of 2,559,016,348 securities (of which BNYM's power to only dispose of 2,559,016,348<br> securities is limited - see Note 1), and Pershing LLC in respect of 969 securities,<br> none of the BNYMC Group entities are entitled to be registered as holder of the securities<br> and their power to vote or dispose of the securities is qualified accordingly.
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print name Kevin Lockhart capacity Attorney-In-Fact
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sign here /s/ Kevin Lockhart date 04/July/2025