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Day One Biopharmaceuticals, Inc.
$21.53 +0.00 (+0.00%) At close · Apr 24
Market Cap
$2.22B
Shares
103,334,169

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$21.53 Open$21.53 Day$21.53–21.53 52W$5.64–21.53 Avg vol 30d2.2M Short int6.6M · 6.4% float · 5.4d Short vol34% Last earningsFeb 24, 2026 DataMay 2021–Apr 2026 Filing10-K · Feb 24
Up next
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed Feb 24, 2026
AI Brief

TL;DR.

Bullish
    Bearish

      AI-generated from the earnings call and 8-K · may contain errors · not investment advice

      Equibles Rating blended score · not investment advice
      Overall
      Buy
      SellHoldBuy
      Technical Buy Momentum Very Strong Sentiment Bullish Fundamentals Fair Quant / Vol Moderate
      Market backdrop VIX 16.5 · calm Equity put/call 0.62
      Technical
      price trend
      Buy
      50 / 200-day cross No cross
      Price vs 200-day avg +99%
      above
      Price vs 50-day avg +17%
      above
      RSI (14) 81
      overbought
      MACD trend Negative
      52-week position 100%
      near high
      Momentum
      relative strength
      Very Strong
      1-month return +1%
      trailing
      6-month return +206%
      trailing
      YTD return +131%
      this year
      Relative strength +201%
      vs S&P · 6-mo
      Sentiment
      smart money
      Bullish
      Trend (MA cross) No cross
      50d $18 › 200d $11 — 50d above 200d
      Institutional flow Accumulating
      +13% holders QoQ · +85 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Falling
      6.37% of float · ▼ -9.1% MoM · 5.4 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Multi-yr high
      211 holders — near 3-yr high, broad support
      Fundamentals
      Fair
      Revenue growth +21%
      Y/Y
      EPS growth −2%
      Y/Y
      Free cash flow $-104.1M
      Balance sheet $197.1M
      net cash
      Quant / Vol
      risk profile
      Moderate
      Volatility 100%
      annualized · 1-yr
      Max drawdown −27%
      past year
      ATR 0.7%
      of price · 14-day

      Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

      Guidance & track record
      Latest guidance · from the Earnings Call filed Dec 31, 2025
      Ojemda net product revenue · for 2026 Initiated $225M – $250M
      prior FY $158.18M midpoint +50.1% Y/Y

      Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

      Technicals

      trend & momentum for long-term holders Buy
      2 · 1 · 3
      50 / 200-day cross
      No cross Neutral
      Price vs 200-day avg
      +99% Bullish
      Price vs 50-day avg
      +17% Bullish
      RSI (14)
      81 Bearish
      MACD trend
      Negative Bearish
      52-week position
      100% Bullish
      Market signals — smart money & positioning
      Bullish · 3 of 6
      Trend (MA cross) No cross
      50d $18 › 200d $11 — 50d above 200d
      Institutional flow Accumulating
      +13% holders QoQ · +85 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Falling
      6.37% of float · ▼ -9.1% MoM · 5.4 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Multi-yr high
      211 holders — near 3-yr high, broad support
      Price context
      position in its 52-week range
      52-wk low $6 Now $22 · 100% 52-wk high $22
      vs 200-day avg +99% vs 50-day avg +17%

      Illustrative technical + ownership context — a signal mix, not investment advice.

      Key metrics

      the company's own KPIs, from its earnings releases, calls, and filings
      Metric Latest Period YoY
      prescription volumes 1,394 Q4 2025

      Figures exactly as the company stated them · click a metric with a to chart its history · period links open the stating document · "call" marks figures stated on the earnings call, "filing" figures stated in the 10-K/10-Q · YoY needs the prior-year figure on file

      Versus peers

      Biotechnology — same industry group
      Open screener →
      Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
      DAWN
      Day One Biopharmaceuticals, Inc.
      this stock
      $2.22B +131.0% +20.6% 6.4%
      ONC
      BeOne Medicines Ltd.
      $439.30B +0.0% +22179.2% 894.0 0.1%
      VRTX
      Vertex Pharmaceuticals Inc / Ma
      $121.89B +5.9% +46.2% 28.5 1.9%
      REGN
      Regeneron Pharmaceuticals, Inc.
      $69.52B -14.0% +20.8% 16.2 3.3%
      ARGX
      Argenx SE
      $53.71B +4.2% 2.3%

      Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

      At a glance

      key data from every section
      Ownership
      Institutional Holders Accumulating
      Holders
      211
      % held
      83.6%
      Net QoQ
      +3.8M sh
      Top holder
      BlackRock, Inc.
      Held Float
      View
      Held by Funds
      Fund positions
      142
      View
      Short & Settlement
      Short Interest Falling
      Shares short
      6.6M
      Days to cover
      5.4d
      Change
      -657.8K sh
      View
      Short Volume
      Short vol %
      34%
      As of
      Apr 22, 2026
      Short Total
      View
      Fails to Deliver
      FTD shares
      65
      Value
      $1.4K
      As of
      Apr 28, 2026
      View
      Off-Exchange
      Off-exchange %
      24.3%
      Week of
      Apr 20, 2026
      Off-exch Lit
      View
      Financials
      Financials
      Revenue (FY)
      $158.2M
      Net income (FY)
      $-107.3B
      EPS diluted
      $-1.04
      View
      Filings
      SEC Filings
      Latest
      8-K
      Filed
      Apr 23, 2026
      This year
      9
      View
      Proposed Sales
      Value
      $179.3K
      Shares
      15.5K
      Filed
      Feb 17, 2026
      View
      Exempt Offerings
      Offering
      $130.0M
      Filed
      Feb 16, 2021
      View
      Earnings & Events
      Earnings Calls
      Last call
      Feb 24, 2026
      View

      Performance

      5D 20D 120D MTD YTD
      DAWN +0.3% +0.6% +205.8% +0.4% +131.0%
      SPY -0.1% +10.0% +4.4% +9.1% +4.1%
      vs SPY +0.3% -9.4% +201.4% -8.7% +126.9%
      Key facts CIK 1845337 CUSIP 23954D109 13F (30d) 1 filings 1 filers Visit website Investor relations