Thank you, operator and thank you all for participating in today's call. Joining me from the company are Mark Iwicki, Chairman, President and Chief Executive Officer; Todd Bazemore, Chief Operating Officer; Mary Reumuth, Chief Financial Officer; and Kim Brazzell, our Chief Medical Officer. Today's call is being webcast live. The webcast link can be found in the Investors and Media section of our website at www.kalarx.com. During this call, we will be referring to non-GAAP financial measures, which are not prepared in accordance with generally accepted accounting principles. A reconciliation of the non-GAAP financial measures to the most directly comparable GAAP measures is available in our press release issued today, which can also be found on our website. On this call, we will make certain comments about Kala's future expectations, plans and prospects that are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements will include statements regarding the potential market and commercial launch plans for EYSUVIS, observations associated with our commercialization of EYSUVIS and INVELTYS and the sufficiency of our cash resources. These and other forward-looking statements are based on the beliefs and expectations of management as of this conference call. Our actual results may differ materially from our expectations. The company undertakes no obligation to revise or update any forward-looking statements to reflect events or circumstances that occur after this conference call, except as required by the law. Investors should carefully read the risks and uncertainties described in today's press release as well as the risk factors, which identify specific factors that may cause actual results or events to differ materially from those described in our forward-looking statements included in the company's quarterly report on Form 10-Q and other filings we make with the SEC. The Form 10-Q will be filed with the SEC later today and will be available on our website. I will now turn the call over to Kala's CEO, Mark Iwicki.

Thanks, Niranjan and good morning everyone. Thank you for joining us today to review Kala's first quarter 2021 financial results and recent business highlights. It's an exciting time at Kala. We now have two commercial products available for eye care professionals and patients, deep relationships across the ophthalmology and optometry markets and are advancing a suite of innovative NCE pipeline programs. Taken together, we are working to extend our reach to address a broad range of front and back of the eye diseases and help millions more patients. We believe this provides us with a tremendous foundation for future growth. As we look to the remainder of 2021, we are working hard to ensure the commercial success of EYSUVIS and INVELTYS. We are pleased with the early EYSUVIS launch feedback from doctors and patients as well as the significant commercial coverage that we've been able to secure in the few months since launch. In addition, we are encouraged by recent trends suggesting that elective ocular surgeries are growing toward pre-COVID levels as vaccines are becoming more readily available. We believe this positions INVELTYS for future growth in the market. We also continue to advance our next wave of therapeutic candidates which includes programs for the treatment of both front and back of the eye diseases. As we have described before, we believe these programs, which include a selective glucocorticoid receptor modulator or SEGRM and a tyrosine kinase inhibitor or TKI have the potential to fuel future growth for Kala by leveraging our existing capabilities and extensive scientific know-how to deliver new solutions for retinal disorders that affect millions of people worldwide. We look forward to providing additional detail around these programs later this year as they move towards clinical development. We believe we're in a strong position to advance our portfolio of innovative products and development programs. This morning, we announced we entered into a new credit facility and increased the funds available to us subject to certain conditions to up to $125 million and also pushed out the beginning of our debt repayment obligations by a minimum of two years. This is an important milestone that ultimately contributes to enhancing our cash runway. We now anticipate that our cash resources as of March 31, 2021 together with anticipated revenue from EYSUVIS and INVELTYS will enable us to fund our operations for at least two years as we continue to invest in our Company. Mary will provide some additional comments about this update later in the call. I will now turn the call over to Todd to review our commercial progress with EYSUVIS and INVELTYS.

Thank you, Mark. I'll begin this morning with the launch update for EYSUVIS. We are pleased to report that as of the week ending April 23rd, data from Symphony Health and our patient hub indicate that more than 11,600 prescriptions for EYSUVIS have been filled, written by more than 2000 unique prescribers since the product launched in early January. In the short period of time, EYSUVIS is quickly establishing itself in the market as an ideal first-line treatment option for dry eye flares. Symphony patient source data indicate that approximately half of all EYSUVIS prescriptions are for treatment of eye patients who previously had not been on a prescription therapy for their dry eye disease. Supporting our belief that EYSUVIS has the potential to become the preferred first-line prescription therapy for dry eye flares. Turning now to execution against two of our strategic priorities for the EYSUVIS launch, ensuring optimal access and broad payer coverage and establishing EYSUVIS as the preferred prescription therapy for the short-term treatment of dry eye disease. Our market access team has done a great job expanding our payer coverage for EYSUVIS. Just four months into launch, we have secured coverage for approximately 43% of commercial lives, totaling approximately 69 million lives. Gaining market access coverage with commercial payers is a core part of our launch strategy in 2021. Commercial payers make up the largest proportion of dry eye prescriptions, and patients with mild-to-moderate dry eye disease are typically younger and are more likely to have commercial health insurance. Earlier in the first quarter, we announced that EYSUVIS was added to Express Scripts' National Preferred, Basic and High Performance Formularies. We also announced that Cigna would add EYSUVIS to their formulary, as a preferred brand effective May 15, 2021. In addition to these two formulary wins, we have secured coverage from other commercial health plans as well including EmblemHealth and Primera. We are incredibly pleased with this level of coverage so early in launch and believe it indicates payer anticipation of significant demand for EYSUVIS. We look forward to further growing our market access coverage this year, which will be a key driver of our prescription growth in the months ahead. With substantial progress underway and building payer coverage, we are also making significant headway into establishing EYSUVIS as a first-line prescription therapy for the short-term treatment of dry eye disease, which includes dry eye flares. We are routinely surveying eye care professionals and market research, and the EYSUVIS awareness is growing. Our most recent survey indicated that nearly 80% of respondents report that they are familiar to extremely familiar with EYSUVIS and in the same survey, nearly 70% of respondents stated that they have already prescribed EYSUVIS. Additionally, survey responses indicate that eye care professionals give EYSUVIS as suitable for a wide range of dry eye patients. We believe these quantitative results are closely linked to the positive anecdotal feedback we have been receiving from eye care professionals since we launched EYSUVIS in January. Physicians consistently comment that EYSUVIS is a very comfortable eyedrop to administer and that patients are benefiting from its rapid onset of action. Eye care professionals report that patients are achieving rapid symptom relief and that they are highly satisfied with how well the product works. In order to support the progress we are making against both securing market access and building demand for EYSUVIS, we plan to initiate our next sales force expansion in the second quarter, increasing from 91 to approximately 105 sales representatives by the start of the third quarter. Then pending continued growth in payer coverage and the status of the COVID-19 pandemic, we plan to further expand our sales force to approximately 125 sales representatives by the end of 2021. We are very pleased with EYSUVIS launch performance to date. The team is executing against our strategic launch priorities and our ongoing efforts as we take the ophthalmology and optometry communities on EYSUVIS is generating significant demand. We look forward to updating you on our launch progress on future calls. Turning now to INVELTYS. As we have shared over the past year, the pandemic has impacted the ocular surgery market. In the first quarter of 2021, approximately 37,000 prescriptions of INVELTYS were reported by Symphony Health compared to 41,000 prescriptions reported in the fourth quarter of 2020. Despite the challenges the pandemic continues to present, we believe that INVELTYS prescriptions and revenues will grow over time. However, we remain unable to project the specific timing or quantify the potential impact on future revenues, given the continued uncertainty around the impact and duration of the COVID-19 pandemic on elective ocular procedures. Now I'd like to turn the call over to Mary to go over our financial results.

Thanks, Todd. During this discussion of our financial results, I will reference certain non-GAAP financial measures. These non-GAAP financial measures exclude stock-based compensation, depreciation, and non-cash interest expense. For a full reconciliation of our GAAP to non-GAAP financial measures, please refer to today's press release which is available on our website. This morning, we announced that we have further strengthened our cash position by entering into a new five-year, $125 million credit facility with Oxford Finance, replacing our existing $75 million facility. The terms of the new facility provide for an initial tranche of $80 million with the ability to borrow two additional tranches totaling $45 million based on meeting certain revenue targets. The terms also eliminate the minimum cash balance required under our previous facility resulting in additional cash on our balance sheet of $10 million. Principal payments will begin in December 2024 at the earliest for two years beyond our previous facility. Additional information regarding the new credit facility is available in the 8-K we filed this morning. As Mark mentioned, we believe this will allow us to invest in our company as we continue to establish our marketed products and advance our preclinical pipeline. Based on our current operational plans, we anticipate that our cash resources as of March 31, 2021, along with anticipated revenue from EYSUVIS and INVELTYS will enable us to fund operations for at least the next two years. Now turning to a recap of the first quarter of 2021, our cash position as of March 31, 2021, is $156 million compared to $153.5 million as of December 31, 2020. This increase primarily reflects net proceeds of $34.7 million received from sales of common stock under our At-The-Market or ATM offering program in the three months ended March 31, 2021, partially offset by cash used in operations. For the period ending March 31, 2021, we reported net product revenues of $3.3 million. This is comprised of $1.63 million from net revenues from INVELTYS sales and $1.64 million of net revenues for EYSUVIS sales. Net product revenues from INVELTYS sales increased approximately $500,000 compared to the first quarter of 2020, in which we reported $1.1 million from sales in INVELTYS. As a reminder, we recognize revenue when product is shipped to wholesalers. Cost of product revenues for the first quarter of 2021 was $800,000 compared to $400,000 for the same period in 2020. The increase was primarily due to the launch of EYSUVIS during the quarter as well as an increase in total INVELTYS units sold during the three months ended March 31, 2021 compared to the three months ended March 31, 2020. Non-GAAP cost of product revenues was $700,000 for the first quarter of 2021 compared to $300,000 for the same period in 2020. SG&A expenses for the first quarter of 2021 were $27.7 million compared to $15.4 million for the same period in 2020. The increase was primarily due to an increase in costs as a result of the launch of EYSUVIS, including expansion of the sales force and increased stock-based compensation costs. Non-GAAP SG&A expenses were $23.8 million for the first quarter of 2021 compared to $13.5 million dollars for the same period in 2020. R&D expenses for the first quarter of 2021 were $3.1 million compared to $5.4 million for the same period in 2020. This decrease was primarily due to a decrease in external spend on STRIDE3 or Phase 3 clinical trial of EYSUVIS, for which we announced positive data in the first quarter of 2020. Non-GAAP R&D expenses were $2.1 million for the first quarter of 2021 compared to $4.6 million for the same period in 2020. Loss from operations for the first quarter of 2021 was $28.3 million compared to $20.1 million for the same period in 2020. Non-GAAP operating loss was $23.4 million for the first quarter of 2021 compared to $17.4 million for the same period in 2020. Net loss for the first quarter of 2021 was $30.4 million or $0.49 per share compared to a net loss of $22 million or $0.54 per share for the same period in 2020. Non-GAAP net loss was $25.2 million for the first quarter of 2021 compared to $19 million for the same period in 2020. Please refer to today's press release for the weighted average number of shares used in the calculation of our net loss per share for each of the quarterly periods discussed. That concludes our prepared remarks for today. I will now pass the call over to the operator for questions.

Our first question comes from Andreas Argyrides with Wedbush.

Hi, this is Andreas for Liana Moussatos. Congrats guys on the quarter. Just a quick question on INVELTYS. What trends are you seeing in the amount of cataract surgeries that give you confidence that they are going to pick up later in the year.

Yes, Andreas. This is Todd, I'm happy to answer that question for you. So we're currently seeing surgical volume roughly at around 80% of its pre-COVID levels. I think what gives us encouragement is obviously the vaccine rollout continuing to go very well combined with the fact that market scope is routinely conducting market research with surgeons to ask them what the impacts of COVID are and what they think future surgical volume will be as the vaccines continue to roll out? And the ophthalmologists are reporting that they expect by the end of the year to be able to return nearly to full pre-COVID surgical volume levels.

I'm going to hop back in the queue and I will ask questions.

Thank you. Our next question comes from Christopher Neyor with JP Morgan.

The first question is about EYSUVIS contracting, specifically ongoing negotiations. Can you discuss your confidence in securing additional contracts in the near term? Additionally, how do you perceive the pace and progress of obtaining payer coverage compared to what you experienced during the INVELTYS launch? Lastly, regarding the EYSUVIS patient hub, what has been your success rate, and what feedback have you received from both physicians and patients, particularly for those without commercial and Medicare coverage? Any insights would be appreciated.

Sure, Chris. This is Todd. I'll try to tick you through those. if I miss something, please don't hesitate to jump back in. We're really pleased with the way the EYSUVIS, a commercial market access is shaping up here and launch here. We do expect additional wins to come; I expect additional wins to come within the second quarter. And as we've always said, we expect that commercial coverage to continue to expand throughout the year and really be the key driver of continued prescription growth as we head into the remaining three quarters of 2021. So feeling really good, I think the team is doing a great job executing on that and we do expect to have additional wins to be able to announce and share with you throughout the year. I think on the hub side, I think like most patient hubs, we're having some success there getting some scripts filled that how this is set up to help us with the prior authorization required for patients whose insurance does not yet have EYSUVIS on formulary. And so that's certainly a short-term solution to help in those situations, but ideally, what we want to be able to do is move away from the hub by securing broad market access having most patients had access to EYSUVIS through their health insurance plan and not require a prior authorization to get the prescription approved and covered. That's going to allow patients when they get the prescription from EYSUVIS to go straight to their local pharmacy, get the script filled, have a benefit, fill their EYSUVIS prescription at a reasonable co-pay and have the ability to start treating their dry eye flare immediately.

Yes, that's very helpful. How should we assess the current mix between the volumes of scripts that are covered versus those that are not?

So I think if you're asking about the actual market access, coverage is about 43% of commercial lives that we now have coverage for EYSUVIS, is that the question you're asking?

Or more so, what percentage of the script volumes that you're seeing are currently covered versus uncovered?

Yes. You look like most newly launched products, most patients' insurance do not yet cover it. And that means that most of the prescriptions that were written certainly in the first quarter did not have insurance coverage and required a prior authorization, and so another thing that gives us great confidence as our market access continues to expand and patients are not requiring prior authorizations, it will have a significant impact on prescription volume growth for the remainder of the year.

Thank you. Our next question comes from Francois Brisebois with Oppenheimer. Your line is now open.

Just wondering, can you help us understand the breakdown a little bit that you're seeing between ophthalmologists and optometrists for prescriptions?

Francois, this is Todd. Good question. Right now, the majority of our prescriptions are being generated by optometrists, about 55% of prescriptions from optometrists, about 45% from ophthalmologists. That's not surprising to us. We know that optometrists tend to treat a little bit younger patient population when it comes to dry eye, who are more likely to have commercial insurance. There are also oftentimes sort of the first-line eye care professional, and so they may be seeing more of the mild-to-moderate patients who are suffering from three, four, or five acute dry eye flares a year and our patients that are ideal as first-line prescription therapy patients for EYSUVIS.

Okay, great. And then on that line of the first-line treatment, can you talk a little bit more about the endpoints that about 50% of your patients are treatment-naive and when you say first-line, just to be very clear here, is it mostly first-line for patients experiencing flares or first-line for patients with dry eye, just simply dry eye?

Yeah. So, to your first question, we're really encouraged by the fact it is early in launch, already half of the EYSUVIS prescriptions are for treatment-naive patients, and those are patients that have not been on a prescription dry eye therapy previously. It's probably we're oftentimes when a new product is launched, you may get used in the more severe patient population that may be on other therapies and you may be used as a chunk of our add-on, but the fact is so early in launch on eye care professionals already going into EYSUVIS as a first-line prescription therapy for many of the patients is really encouraging. And when we talk about first-line, I think certainly for a patient that's experiencing dry eye flares, we think that's a lot of where the prescriptions are going. But remember, that's the majority of all dry eye patients. Across multiple quantitative research studies, it's indicated that anywhere from 80% to 90% of diagnosed dry eye patients suffer from these acute flares. We also know that only about 10% of those diagnosed patients are currently on one of the FDA-approved chronic dry eye medications. So we think that means that the majority of diagnosed dry eye patients are great candidates for first-line prescription therapy for EYSUVIS.

Okay. Now, that's very helpful. And then lastly if you can just help us here, where are we exactly in terms of reimbursement, you just mentioned, again the wins, their dates of effectiveness and what you would expect once something is effective, is a kind of a bowers, kind of a pent-up demand or is it slow? And then just lastly, if you can touch on the percentage of patients here that are commercial versus Medicare?

Sure, I'll start with the latter. About 50% of all dry eye prescriptions are reimbursed by commercial payers, around 40% that are Medicare and the remaining 10% is some mix of cash and Medicaid. The Cigna contract goes live here in just a couple of weeks; ESI has been live since the beginning of February, and I think the team is doing a great job getting out there and communicating and educating eye care professionals about where there is access, which patients' insurance covers EYSUVIS. This means they're able to write those prescriptions and get the prescription filled without having to call back from the pharmacists. So yes, they are continuing doing a great job, and we will continue to communicate that. We're just a couple of weeks now from Cigna rolling out with that coverage, and I'm really confident in the team's ability to drive prescriptions if that coverage comes online.

Thank you. Our next question comes from Tazeen Ahmad with Bank of America.

Hi. Can you tell us if you have any sense yet about the number of bottles per year that are going to be utilized by each patient? I know you still early in the launch trajectory, but are you noticing any trends on that and then I have a couple of follow-ups.

Tazeen, it's Todd. To your point, it's still too early to know the number of refills. Just four months into launch, but we do have some transparency to us with the scripts that have come into the hub. What percentage of those scripts have been written with refills? Currently, it's about two-thirds of all of our prescriptions that we've seen at the hub were written with refills attached to them. So that gives us really good confidence that most of the scripts have been met with refills and so as patients use their first follow-up, I see this and then experience additional players and need a refill, be able to go and get it, without having to go back to the doctor's office for another prescription.

And how many refills are they allowing?

It varies. The majority of the refills are being written for more than two refills. But we're seeing great variance on that. We've seen some as low as 1 refill to some sort of as many as 10 refills.

In the first four months since the launch, can you provide any estimates on the impact of COVID, and as the country reopens, how do you expect the easing of restrictions to affect the duration of the launch?

Yeah. It's a really good question. We are definitely seeing impacts. I think the biggest impact is just on our sales representatives' ability to get in and see their customers face to face and have really meaningful sales interactions. It is currently probably about 65% to 70% of our eye care professionals that we're actually able to get in and see face to face. As you can imagine, the salesforce is really focused their efforts in the first quarter on our high-decile customers that they can actually get in and see. As time goes on and more of those practices get comfortable allowing sales reps back in, I think that will certainly have a positive impact. It will give us a chance to get in and detail more eye care professionals, make sure they have samples and co-pay cards, which is going to be really important for expanding our reach.

Okay. We've heard as discussed before, but I was curious if you have updated thoughts on the number of visits the sales rep might need to make to our physicians' practice to result in scripts being written. Has that evolved during the course of the pandemic?

Yes, I would say also a little too early to say. We are standing, it typically takes multiple sales calls to get in. Those sales calls involved talking about dry eye flares, identifying if those patients are in the practice, appropriately positioning EYSUVIS as a first-line prescription therapy for those patients. So too early to say on the exact number of calls per term. We are certainly seeing that it takes a few sales calls before an eye care professional adopts and begins prescribing EYSUVIS.

Okay. And then, have you adopted virtual doctor visits? I guess zoom calls or anything like that.

Yeah, we certainly have virtual targets in place. They involve both rep to eyecare professional interactions as well as, we have done some virtual peer programs, with some of our speaker programs that can be done virtually as well.

Okay, great. And maybe just moving on, one more question. Beyond marketed products, you talked about a pipeline of pre-clinical assets, both for the front and back of the eye and wondering when we could get some more color about those, and when they might enter the clinic?

Yes, I'll hand it over to Kam.

Yes. What we've said publicly is on our SEGRM program, our target is to identify a lead compound by the end of this year, 2021 and then to begin the IND enabling work that would let us get into the clinic, hopefully within 12 to 18 months of that time.

So you would identify by the end of this year 2021.

Yes.

Thank you. Our next question comes from Yi Chen with H.C. Wainwright.

How many eyecare professionals have been reached by the sales team from January to April and what are the reasons for those that have not prescribed EYSUVIS.

Yes. This is Todd, I'm happy to answer that question. As I was saying earlier, it's probably about in the range of 65% to 70% of our eye care professionals that we're able to see face to face. We have certainly gotten to those eyecare professionals. We have others that we're getting through virtual promotion. The sales force has spent most of this time as you can imagine during the first quarter focused on the higher decile targets that we're able to get in and see face-to-face. We believe from the market research and the feedback we've got that eyecare professionals are very enthusiastic about EYSUVIS. As we said in the most recent round of quantitative research, 70% had said they had already written a prescription for EYSUVIS. We think the biggest thing that we can do to help them at this point is to continue to improve market access and generate on-payer coverage. So, that a larger percentage of the prescriptions that are being written end up in a filled prescription that's covered by the patient's insurance.

Okay. Could you give us an update on the usage of the patient access program?

Sure. I mean, are you referring to the hub or are you referring to our co-pay card?

The co-pay card.

Yes, it's a little less than half of the prescriptions are coming in; they were getting filled with the co-pay card.

Thank you. Our next question comes from Tim Chiang with Northland Securities. Your line is now open.

I know you guys mentioned that you have about 43% coverage secured with market access for EYSUVIS. What is the target? What do you think that figure will be by year-end?

Tim, we have not set a specific target or have not externally communicated a specific target for market access by year-end. We've just said that our goal is to obtain broad market access coverage within commercial payers by the end of 2021, with really a focus for Medicare coverage to start coming online in 2022.

Okay, and maybe just a follow-up. As we get to the reopen, what sort of major medical conferences are you guys going to be attending near term and throughout this year, that sort of increases the awareness for your products? Obviously, I think a lot of ophthalmologists and optometrists, they are much more interested in new products. So I was just sort of wondering, what sort of conferences you guys are going to be attending.

Yes, we will be at all of them and we're really pleased that these conferences starting to come back online and in-person meetings. So this past week was the big optometry conference down in Atlanta. It's an in-person event, and we had great representation there. A number of programs ongoing. The whole Eye conference will be going on next week, that is largely attended by ophthalmologists, and again that meeting will be in person. So as these conferences start to occur in person, we will have a significant presence, both of our medical affairs department and our commercial teams at each of the conferences.

Okay, great. And maybe just one last question, just sort of, I don't think you will be able to answer it. But obviously, how do you sort of look at your prices for both EYSUVIS and INVELTYS throughout the course of this year and next? Obviously, you signed some contracts here, you've got to whack price for us, it was around $460. Anything you can highlight and just in terms of where the gross to net discounts are at this point, and are they pretty much in line with what other new products add in terms of that discount.

Yes. I certainly appreciate the question, Tim. As you know, we're not providing direct guidance on net revenues or gross to net. But I think it's a fair statement to say that similar to other new product launches, we expect there to be deeper discounts in the first few quarters of launch when you start to account for things like initial trade distribution and patient assistance programs, and expect those gross to nets to improve over time as we secure broader market access coverage at that point or just paying rebates to the payers as opposed to a lot of the other patient access programs that you have to initially put in place at launch.

Thank you. Our next question comes from Kelly Shi with Jefferies. Your line is now open.

This is Kelly Shi from Jefferies. My first question is a follow-up on the COVID impact. Have you seen gradual recovery in Q2 on the new patient starts on EYSUVIS given the vaccination has accelerated in the United States? And do you expect to see full recovery of regular doctor office visits? And also have a second question, I wonder if you have market research data informed. What percentage of the dry patients treated with steroids as a frontline treatment of acute flares and do you see a difference on prescribing steroids between optometrists and ophthalmologists?

Sure, I'll tell you, I'll try to kick to each of those. Please don't hesitate to jump in if there is something that I missed. I think in terms of COVID impacts, as I said earlier, we're encouraged with the vaccine rollout. I think at this point, it's estimated that roughly around 56% to 57% of the U.S. population has received at least one shot. Obviously hard for us to predict what future quarters are going to look like, and how the rest of the rollout of vaccinations is going to go, but we're optimistic. We are certainly seeing more practices that we're able to get into, and see the eye care professionals face to face, certainly just point compared to back in the winter when we were dealing with the second wave of spikes in cases being reported. So that appears to be improving. Certainly we have seen really good prescription volume growth for both INVELTYS and EYSUVIS in the second quarter looking at the weekly data compared to first quarter. So a lot of really positive signs there. As far as your next question about the split and use of the product, we are seeing at this point about 55% of prescriptions being generated by optometrists, about 45% by ophthalmologists. So the optometrists do appear to be early adopters of EYSUVIS, and we certainly anticipated that based on a lot of the market research we did to prepare for launch. And understanding that a lot of those patients with more mild to moderate dry eye disease who do not have chronic persistent symptoms on a daily basis and are really not candidates for chronic maintenance therapy and medication, patients who are better suited to be treated with a short-term treatment of a few times a year like eyedrops. Those patients are largely treated by the optometrists, and so we are not surprised by the fact that they are early adopters. And then you asked about general use of steroids to treat dry eye flares. It's been quite limited, only about 3% of the 17.5 million diagnosed dry eye patients previously would get a prescription for steroids and off-label steroids. There are certainly certain subsets, some physicians like corneal specialists that are more comfortable still reducing more steroids, but when you look broadly across sort of all optometrists and ophthalmologists, it's only previously about 3% of diagnosed dry eye patients who receive off-label steroids, and of course, we expect that to grow significantly now with EYSUVIS' approval and having an on-label steroid to treat the acute dry eye flares.

Thank you. I'm not showing any further questions at this time. I would now like to turn the call back over to Mark Iwicki for closing remarks.

Thank you everyone for joining us this morning. We're really pleased with progress on the business and especially the early indicators of launch success with EYSUVIS. We look forward to updating everyone soon and hope everyone stays safe. Thank you.

This concludes today's conference call. Thank you for participating. You may now disconnect.