Thank you for joining us today for Materialise's quarterly conference call. With us on the call are Fried Vancraen, Founder and Chief Executive Officer of Materialise. Peter Leys, Executive Chairman, and Johan Albrecht, Chief Financial Officer. Today's call and webcast are being accompanied by a slide presentation that reviews Materialise's strategic, financial, and operational performance for the fourth quarter of 2021. To access the slides, if you haven't already done so, please go to the Investor Relations section of the company's website at www.materialise.com. The earnings release that was issued earlier today can also be found on that page. Before we get started, I'd like to remind you that management may make forward-looking statements regarding the Company's plans, expectations, and growth prospects, among other things. These forward-looking statements are subject to known and unknown uncertainties and risks that could cause actual results to differ materially from the expectations expressed, including competitive dynamics and industry change. Any forward-looking statements, including those related to the Company's future results and activities, represent management's estimates as of today and should not be relied upon as representing their estimates as of any subsequent date. Management disclaims any duty to update or revise any forward-looking statements to reflect future events or changes in expectations. A more detailed description of the risks and uncertainties and other factors that could impact the Company's future business or financial results can be found in the Company's most recent annual report on Form 20-F filed with the SEC. Finally, management will discuss certain non-IFRS measures on today's call. A reconciliation table is contained in the earnings release and at the end of the slide presentation. With that introduction, I'd like to turn the call over to Peter Leys. Go ahead, please, Peter.

Thank you, Harriet. And good morning, and good afternoon, everybody. Before turning to Slide 4, which summarizes the highlights of our Q4 and 2021 full year financial results, I would like to emphasize that our focus and actions today are centered on the safety and well-being of our Ukrainian collaborators. Their lives and security are of utmost importance to us. Fried will address the actions we are taking to assist them during his remarks. Now, turning to our 2021 results. Some of you may remember in the third quarter of 2021, Materialise boasted all-time quarterly records both in terms of revenues and in terms of EBITDA. Today, we can announce that none of the Q3 records are still on the books for the simple reason that they have been surpassed by the all-time higher revenues and adjusted EBITDA that we posted in the fourth quarter. Driven by very robust revenue growth in each of our segments, our consolidated Q4 revenues increased by more than 25% to a quarterly all-time high of close to €57 million. Our adjusted EBITDA for the quarter was €10.5 million, representing a margin of 18.4%. Our net profit for the quarter was almost €4.8 million. In particular, our software and medical segments realized very strong EBITDA margins in the fourth quarter, software more than 45%, and medical more than 30%. For completeness's sake, I should add that also for the full-year 2021, our revenue adjusted EBITDA and net profits are all-time records. Johan will fill you in on those numbers later. These results show that our strategy of continuing to invest throughout the COVID-19 pandemic in our people in general, and in the research and development in particular, was the right choice and is already paying off in the short term. I would like to now pass the floor to Fried, who will walk you through some of the key operational achievements of Materialise in 2021.

Good morning and good afternoon, everyone. Before turning to our operational achievements in 2021, I want to reiterate what Peter just said with respect to Ukraine. I am, together with other members of our executive committee, in daily contact with the leadership of our Ukrainian office. We are trying to help our team members there as much as we can through a variety of different avenues. The assistance we offer includes providing alternative housing and office space both within and outside of Ukraine. In spite of the hostilities they are facing, many of our collaborators continue to contribute to the projects they are working on by making maximum use of the flexible working conditions we installed during the COVID crisis. Simultaneously, many of our people around the globe are adjusting their activities and priorities and stepping in to assist wherever they can. We want to express deep admiration and respect for the courage, dedication, and professionalism that the collaborators in Ukraine have shown in circumstances where their safety and the safety of their beloved ones is constantly at stake. In 2021, a year that was still dominated by COVID restrictions and impacted by supply chain issues, I'm very proud of the collective performance of all Materialise employees. As peak has already outlined, we delivered a good performance both in terms of revenue and profitability, and this is for the second quarter in a row. In a world with many restrictions and limited budgets, we grew our top and bottom lines compared to not only 2020, but also to 2019, while also reducing our carbon footprint drastically across all our segments. Our global operations performed well in the new digital and work-from-home context. Our production lines have shown to provide safe and effective work environments for our workforce during different phases of COVID infections. Most importantly, we did all this while maintaining our R&D spending to secure our future. Most of the new products that will ensure the company's future growth would not be possible without the sustained research and development efforts. Overall, we believe our consistent performance during the crisis period has strengthened our position in the markets we serve and has demonstrated to our customers and partners that Materialise is a sustainable company, one they can rely on for their long-term future. Let's look at some of the specific achievements at the level of our three segments. Our medical software for engineering anatomy, the Mimics Innovation Suite, realized revenues of almost €23 million in 2021. That proves that the Mimics Innovation Suite is essential for many engineers that want to develop or produce medical devices based on medical image data. The growth was driven by new models that aid and make use of artificial intelligence or that enable users to link with their own artificial intelligence developments. Similarly, the Mimics Innovation Suite has also become an engine to explore and develop new augmented reality and virtual reality applications in the medical field. This has led to growth in both the medical device company and the hospital markets, where we will be able to support medical treatments in the future. Our Medical Device activity had very strong growth, especially in cranio-maxillofacial surgery in an extremely volatile environment. With hospitals making certain shifts in prioritization due to COVID, our design and production team succeeded in providing constant service. Additionally, in the middle of the challenging COVID-related circumstances, we were one of the first companies to bring our mass customization of medical guides and implants fully in line with the new European Medical Device Directive. This significantly increases the hurdles for new medical product introductions in the European market. On top of that, we managed to create several CMF products in our subsidiary engine brand for the European market. Finally, the engine plant itself became a 100% subsidiary of Materialise, fully focused on CMF and osteosynthesis as we've been concluding other business with former owners. Increased focus and stronger offerings should enable us to capture additional market share, both in Brazil and in Europe. Our manufacturing is back on track with the highest growth numbers of all our segments. Despite the production limitations in the civil aerospace on which we focused, we are seeing healthy growth thanks to the promising segment of eVTOL as explained during our Q3 call. The key driver of the recovery in the business systems segment is where we focus a lot on healthcare equipment. There, we have been seeing an increase in the use of additive manufacturing for small production series. Thanks to our wide offering with engineering support and multiple AM technologies, Materialise is well-placed to support the companies in those markets for which we expect healthy growth and development in the near future. Finally, also important to the manufacturing segment's growth is the considerable growth in the Eyewear and Motion business. For Motion, we integrated at a scan and at sprint into Materialise motion, as did the preparatory work to launch new product lines during 2022. Our software segment has launched a series of impactful innovation initiatives from a strong base. The strong basis Magics consistently grew its user community during 2021. Even after being on the market for 30 years, Magics was chosen by the readers of 3D Print as the AM Software of 2021. We are confident that the R&D initiatives we executed in 2021 will make it even stronger. We relaunched Metrics 26 in '22, with a fully integrated but robust GSK Kernel from Siemens. This will enable it to integrate even better with design and post-processing workflows. The new metrics will also be compatible with the Zinc 3D CEMEA system and finish no embedding of testing. The beds of tests for process journals and workflow automation are also running successfully. As we speak, the beds of testing of storefronts are being launched. In short, after the serious development efforts of 2021, 2022 will be the year when multiple releases of new products fitting our broader cloud strategy will take place. During our next earnings call with the official releases at AMR and Rapid, I will provide further details on our cloud strategy.

Thank you, Chris. I'll begin with a brief review of our consolidated revenue on Slide 6 now. As a reminder, when we refer to sales in our presentation, we mean revenues plus deferred revenues. Please note that unless otherwise stated, all comparisons in this call are against our results for the fourth quarter of 2020 and the full year 2020. For the quarter, revenue increased 25.8% to €57 million. The growth took place in all three segments. Our software segment grew by 19%, Materialise Medical increased 20%, and revenue in manufacturing rose by 35%. For the quarter, Materialise Software accounted for 22% of our total revenue, Materialise Medical for 36%, and Materialise Manufacturing for 42%. For the full year, revenue grew €35 million or 20.5% to €205.5 million, including a €4 million increase in our deferred revenue from software license and maintenance fees compared to December 2020. This underscores the strong license sales performance of our software and medical segments. Cross-segment revenue from software products represented 32% of our total revenue for both the quarter and the full year. Moving to Slide 7, you will see our consolidated adjusted EBITDA numbers for the fourth quarter. Consolidated adjusted EBITDA increased by €3.1 million to €10.49 million compared to Q4 last year and achieved new quarterly records. Our EBITDA margin grew to 18.4%, two percentage points above last year's 16.3%. Full-year EBITDA grew 50 basis points from €20.4 million in 2020 to €32.5 million in 2021. EBITDA margin for the full year reached 15.8% compared to 12% last year. This increase resulted from various positive factors including our strong revenue growth, improved gross margin, driven by increased insourcing and continuous productivity improvements along with disciplined spending, in particular with respect to overheads. Importantly, our EBITDA increase did not come at the expense of our R&D spending. Moreover, the initiatives we previously described to enhance our internal business application platform continued and are on track. Slide 8 summarizes the results of our Materialise software segment. Software revenue increased 19.3% to €12.2 million. Meanwhile, recurring revenue and non-recurring revenue grew 33.6%, driven by new perpetual license fees. EBITDA increased 43% to €5.5 million. The adjusted EBITDA margin grew to 45% as a result of solid revenue growth and our operating expenses being managed carefully even as our digital transformation project progressed. Moving now to Slide 9, you will see that the total revenue for the Materialise Medical segment increased 20.3%, and for the first time, it broke the €20 million barrier. Revenue from medical software sales grew 25%, while revenue from medical devices and services increased 18% compared to last year. Revenue from medical software sales accounted for 31% of the segment revenue. Adjusted EBITDA grew 31% to €6.358 million compared to €4.8 million. The segment's adjusted EBITDA margin was 30.7% compared to 28.2% last year. Let’s turn to Slide 10 for an overview of the Q4 performance of our Materialise Manufacturing segment. Revenue increased 34.9% to €24.1 million. Importantly, revenue was approximately €5 million higher than in the first quarter of 2021, when we first noted the positive signs from industrial goods across all business lines. Adjusted EBITDA for the quarter was €1.2 million, with an EBITDA margin of 5%, negatively impacted by temporarily higher production variables in our additive manufacturing business lines. Full-year adjusted EBITDA increased €3.9 million to €6.4 million, while EBITDA margin increased to 7.2% from 3.7%, as a result of revenue growth, optimized capacity usage, and improved production efficiencies. Slide 11 provides the highlights of our income statement for the fourth quarter and the full year 2021. For the quarter, revenue increased by €11.7 million or 25.8%, and gross profit increased by €7 million or 26.9%. Gross profit was positively impacted by efficiency gains and the growing software and service portions in our revenue sales mix. As a result, gross profit margin increased by 0.5 percentage points to 58.3%. For the full year, this margin even increased by 1.9 percentage points. Operating expenses increased by 5.9% compared to last year's quarter. Our sales and marketing spending increased by 22.7% as sales and marketing projects were refined. G&A expenditures increased 11.3%, due to the rollout of the ongoing internal digital transformation project discussed in our previous earnings calls. In line with our strategy, research and development expenses increased by 12.2% compared to Q4 if we exclude last year's €2.1 million impairment cost of our tracheal splint program. This quarter, net operating income was €1.26 million. As a result of these elements, the group's operating profit amounted to €4.976 million compared to a loss of almost €2 million in last year's period. For the full year, operating profit rose to €12.217 million from a loss of €4.639 million. Net financial income was €275,000 compared to a loss of €596,000 last year. Income tax expense amounted to €490,000 compared to Q4 2020's positive tax income of €531,000. Net profit for the fourth quarter was €4.762 million compared to a net loss of €2.039 million for the 2020 period. For the full year, the profit rose to €13.145 million, resulting in €0.23 per share from a net loss of €7.2 million or a loss of €0.13 per share. Now please turn to Slide 12 for a recap of balance sheet and cash flow highlights. In this fourth quarter, our balance sheet remains strong. Cash amounted to €196 million compared to €111.5 million at December 31st, 2020. Over the same period, our borrowings decreased by €16 million to €99.1 million. Only €21.3 million of our debt is short-term as of December 31st. Equity increased by €99.4 million to €232.6 million as a combined result of the year-to-date net profits amounting to €13.1 million and growth from the June and July follow-on capital increase of €85.8 million. The exercise of stock options for €2.4 million, the impairments over financial assets in a span of €3.4 million over the year '21, and positive conversion differences of €1 million mainly from the strong US dollar against the Euro. Total deferred revenue increased to €38.3 million compared to €34.9 million as of December 31st, 2020. Of the €38.3 million, €34.3 million were related to annual software sales and maintenance contracts versus €30.2 million as of December 31st, 2020. Cash flow from operating activities for the full year amounted to €25.8 million compared to €30 million last year. The increased operating result was partly offset by unfavorable working capital requirements due to strong activity growth. Capital expenditures for the quarter amounted to €4.5 million and €11.7 million for the year, and they were not financed. Our financial reports are excluding Link3D, of which we acquired 100% of the shares through January 4, 2022. As referenced in 2021, Link3D realized revenue of approximately $2.3 million, and the negative EBITDA of approximately $4.6 million.

Thank you, Johan. If you could kindly turn to Slide 13. Encouraged by our very strong results in the second half of 2021, we believe our more mature business lines in particular, our Magics software suite, our Mimics Innovation Suite, and our personalized medical device business lines, all have the potential of continuing to scale solidly with a healthy margin, and we plan to support these businesses accordingly in 2022. Simultaneously, we have the ambition to significantly increase our spending in 2022, especially in R&D and sales and marketing, with a view to accelerating the development of our new growth businesses, which includes our software cloud platform, including the newly acquired Link3D solutions, and our medical and wearable verticals. We believe that the combined growth of our more mature and newer business lines, including Link3D, will generate consolidated revenue growth in 2022 of at least 10% compared to the previous year. As we will allocate significant portions of the expanding EBITDA margins of some of our more mature business lines towards increased investments in our newer growth businesses, in particular, building 3D product portfolios, we expect our consolidated adjusted EBITDA to decrease by approximately 10% compared to last year. This outlook for 2022 does not take into account the very recent events in Ukraine. As a reminder, we have no meaningful sales in Ukraine or in Russia. Our 430 collaborators in Ukraine are mainly active in engineering, software development, and supporting IT and staff functions. As Fried explained earlier, we believe that the impact of the war in Ukraine for our customers and for the continuity of our business will be minimal because many of our people in Ukraine continue to work whenever they can, and Materialise colleagues with similar skills and competencies elsewhere in the world are stepping in to assist them whenever that is needed. Nevertheless, the recent onset of hostilities in Ukraine does add a level of complexity to our outlook for 2022 as we currently cannot assess how long they will last or how the global economy will react to the sanctions being imposed upon Russia. We hope to have more visibility on these events, which are very disturbing to all of us, and their potential short-term impact on our business when we release our first quarter results. And on this note, I would now like to open the floor for questions. Operator, please go ahead.

Thank you. Our first question comes from Troy Jensen from Lake Street Capital. Your line is open.

Hey, gentlemen. Congrats on the great fourth quarter.

Thank you, Troy.

Hey, Peter, I just want to start off with software. I guess I was happy to see that up nicely; it had been stuck at about a $10 million quarterly level. It sounds like Mimics grew faster. I think I read in the press earlier in the slide; there was 25% growth, but the segment was up 19%. But I guess I just want to confirm that Magics and Streamics are still growing kind of in the high teens; is that correct?

Well, actually the Magics growth is not in the high teens, but close to 10%. The Streamics is actually being replaced by Link3D in the future. But we see a healthy growth in the sales, and we expect that the new cloud platform will really become a good driver in the future.

Great. I sure hope so. How about just specifically to Q1 in the healthcare segment? I think of you guys as fairly exposed to elective surgeries. Obviously, with COVID spiking back in January and February, just the concern that Q1 may be seasonally weaker than we've historically seen?

Troy, we had that experience of elective surgeries being postponed due to COVID-related treatments earlier. But frankly, the impact, as our numbers show, of COVID on businesses and on surgeries that we support being again, picked up is minimal.

Good. All right. Okay. I was fearing the Omicron spike might really slow that down. About that to Fried medical point of care, I hear more point-of-care applications for medical. Is that something that you guys favor, or do you prefer more centralized? I guess to me, it's good for Mimics sales, but just thoughts on the importance.

Well, we have a balanced view. We favor point-of-care solutions, especially with respect to vitalization models, and 3D planning models, and the like. We do believe that on the other side, on the implant side, a more centralized approach is the only feasible one if you want to comply with all regulatory requirements, and we have proven that we can elaborate high-volume, patient-specific solutions of implants with a quality level that is similar to standardized implants. I think this is very difficult if you do this in a very distributed way of working.

Great. Pretty good answer. That's okay. About last question from me in manufacturing has been a great segment here recently. Could you just call it again? I thought I heard you say maybe European auto was weak. But what was strong in the quarter for you guys in manufacturing?

We observe a significant utilization of 3D printing in the industrial and healthcare equipment segment, indicating a notable structural change and growth in this area for small series of complex equipment. 3D printing is becoming increasingly vital in this context. We view this as a region where manufacturing has substantial growth potential in a sustainable manner.

Great. At some point you said more import production applications are driving the business in. Am I correct?

Yes.

Awesome. All right, guys. Keep up the good work.

Thank you, Troy.

Thank you.

Your next question is from Jason Celino from KeyBanc Capital Markets. Your line is open.

Hi, thank you. This is actually Devin Au for Jason. First question I have is around the 2022 guidance. I know that there is a lot of near-term geopolitical uncertainty. But in terms of other macro factors, like supply chain disruptions that you and the customers faced during the past couple of years, what is your expectation of macro challenges trending in 2022? Do you expect some improvement? Any color you could put on that?

As Fried explained earlier, the strong growth in manufacturing has been realized to some extent by being able to focus on other sectors than just the automotive sector. The business systems in general and the healthcare applications, in particular, is something that we have focused on and that has helped us in restoring growth. This shift allows us to really show strong growth now. If automotive picks up in the course of 2022, we've been saying this for a couple of years now, that if it does pick up, that should only further foster strong performance of our manufacturing in 2022. Let's wait and see.

Got it. That's helpful. And then maybe one more on gross margin. It’s a nice step up to 57% in 2021. Any color you can provide on how we should think about that margin in 2022, as manufacturing rebounded nicely in 2021? Should we continue to expect a gradual step up in margin as that segment grows and benefits from leverage?

We expect quite a gradual improvement of the margins in manufacturing. We have a temporary lesser margin in the fourth quarter, which we anticipate will improve again gradually.

Got it. Thanks, guys, and congrats on the good results.

Thank you.

Thank you.

We have a question from Noelle Dilts from Stifel. Your line is open.

Hi. Good morning. Congrats on a strong quarter. I really only had one major question, which is, I think the investments that you're talking about making in R&D and sales and marketing make a lot of sense for 2022. But I was hoping you could discuss how we should think about the returns on those investments. Are you expecting to maintain higher levels of investment going into 2023 and 2024? How should we just think about this from a longer-term business model perspective? Thanks.

Noelle, just for 2022, to begin with, I think you can expect an uptick of those investments more in the second half than in the first half of the year, as we are ramping up recruitment of the developers that we are currently looking for. These investments will not stop in 2023. We do expect that sales, particularly of the Link3D, and more generally, the Magics cloud platform, will actually start showing up in our P&L more in 2023 than in 2022. So, 2022 will really be a year where it will involve significant investments with not much additional revenue coming from these investments. Hitting our P&L significantly in 2023 and, more importantly, the years thereafter, we expect that our investments in the Link3D platform will actually show the recurring revenue that we are aiming for.

Next question is from Gregory Ramirez from Bryan Garnier. Your line is open.

Hi, good afternoon. Thank you for taking my questions. First, regarding the software division in Q4, how should we understand the increase in software revenues, particularly from Materialise products like Magics? It seems to be driven by new licenses. Is this linked to specific orders from 3D printing manufacturers? Should we view it as a one-time occurrence due to the year-end, or is it related to upgrades on existing machines? I also have a question about the expected growth structure for 2022, which is anticipated to be over 10%. You mentioned that software and medical sectors are showing strong trends. However, it seems that this is particularly influenced by the automotive sector. Is there any specific reason we should believe that the growth in the manufacturing division will be significantly lower in 2022? Lastly, I would like to ask about the adjusted EBITDA guidance for '22. What can we expect regarding the potentially negative impact on EBITDA from Link3D? It appears that the decline in EBITDA for '22 is largely attributed to the Link3D acquisition.

Thank you, Gregory. We hope to have addressed your many questions. To summarize, regarding your first question about the software growth approaching 20% in Q4, it is traditionally a strong quarter for software sales. Therefore, the 20% growth we reported in the last quarter is certainly, in part, related to the fact that we are discussing Q4, the final quarter of the year.

Yes.

Well, manufacturing posted spectacular 35% plus growth this quarter. It's basically significant growth because of the comparison with the previous quarter which was significantly weak due to the COVID-19 crisis. So, we're basically filling our capacity again, and we will continue to fill our capacity in 2022. Once we get to that level the focus will be on making the right choices and ensuring we fill our capacity with products that generate the best possible margin, and there we believe that some of the healthcare applications I alluded to earlier should help us in improving the margin of manufacturing. The rebound is what manufacturing is currently experiencing. That being said, as part of our manufacturing segments, we are also reporting wearables businesses, our eyewear and our motion business, and we believe they will continue to contribute to some of the growth we expect to report in 2022.

Your last question related to the EBITDA profile for 2022 and the role that Link3D will play there. The short answer to your question is, yes, the bulk of the negative investments contributing negatively to our EBITDA in 2022 will be linked to the development of our software Cloud platform. This, of course, includes continued investments in the product portfolio that we acquired from Link3D.

Thank you. And just to come back on the first quarter inquiry. So do you confirm there is, I would say, no specific one-off there for almost 20% growth in software in Q4?

There is no specific one-off. It's well distributed. But again, as Peter mentioned for manufacturing, that reference year of 2020 was, of course, a weak year.

Thank you very much.

Q4 was strong, especially when compared to the weaker Q4 from the previous year.

Thank you very much.

Thank you, Gregory.

Thank you.

And our last question is from Bhavna Advani with JPMorgan. Your line is open.

Hi, this is Bhavna for Paul Chung from JPMorgan. I have a little more question. So on the EBITDA margin, just going back, can you talk a little bit about where you see that going in '23? Do you see some of the return on investment on top line and how can you look at the margin outlook?

We tried to guide for the year. So guiding for 2022 we are not really guiding for 2023. But as I said earlier on, while 2022 will be hit significantly with lots of investments and not that much additional revenue, we expect to continue the level of investments in 2023. We do expect that several revenues will compensate those revenues in 2023. However, the bulk of the return is more likely to come in the years thereafter.

As support businesses will also continue to grow, that's just to be said, we will have expanding margins and realize scale effects. It should go back to the higher margins as we utilize this year, along with the continued positive evolution.

Thank you, Johan. My comment only related to basically investments in the software cloud platform and not on a consolidated basis in general. Yes, thank you.

I see. Then going to the revenue contribution. Can you speak at all about what you'd expect Link3D to bring in in 2022, both on sales and EBITDA?

Okay. We do not intend to continue to give separate numbers for Link3D. Also because we will be quickly integrating the product. But roughly, we provided you the numbers of the revenue that Link3D generated in 2021 in terms of contribution. By linking 3D to revenue in 2022, we do not expect significant increases there.

Got it. Those were all my questions. Thank you. Congrats on the good quarter.

We do expect an increase; I mean, it was a negative $4.6 million. We expect just to be sure to increase the quote-unquote negative EBITDA coming from that product line.

There are no further questions at this time. I would now like to turn the conference back to Mr. Peter Leys.

Thank you, Operator, and thank you again all for joining us today. We also want to thank our employees around the globe for their dedication and contributions. On behalf of all members of the Materialise family, I would like to convey the following closing message to our colleagues and friends in Ukraine. Dear colleagues, we admire your courage. You are an inspiration to all of us. We stand behind each and every one of you. Please take good care of yourselves. Thank you.

This concludes today's conference call. Thank you for joining. You may now disconnect.