Good day, everyone, and welcome to PsychSciences' fourth quarter 2025 earnings results. At this time, all participants are in a listen-only mode. After the presentation, there will be a question and answer session. To participate, you will need to press star 1-1 on your telephone. You will then hear a message advising your hand is raised. To withdraw your question, simply press star 1-1 again. Please note, this conference is being recorded. Now it's my pleasure to turn the call over to Tripp Taylor with Investor Relations. Please proceed.

Thank you for participating in today's call. Presenting today are Sight Sciences Co-Founder and Chief Executive Officer, Paul Baddawi, and Chief Financial Officer, Jim Rodberg. Also in attendance is Sight Sciences Chief Operating Officer, Allie Ballerlein. Earlier today, SiteSciences released its financial results for the fourth quarter ended December 31, 2025, and initiated its revenue guidance and adjusted operating expense guidance for full year 2026. A copy of the press release is available on our website at investors.sitesciences.com. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements, including statements about material business considerations, 2026 outlook, and financial guidance. These statements are based on plans and expectations as of today, which may change over time. In addition, actual results could differ materially from projected results due to a number of risks and uncertainties. For a discussion of factors that may affect the company's future financial results in business, please refer to the earnings release issued prior to this call and the company's most recent SEC filings. We undertake no obligation to publicly update or revise any forward-looking statements except as required by law. Also on this call, management refers to certain financial measures that were not prepared in accordance with generally accepted accounting principles in the United States, including adjusted operating expenses. We believe that these non-GAAP financial measures are important indicators of the company's operating performance because they exclude items that are unrelated to and may not be indicative of its core operating results. See our earnings release for a reconciliation of these non-GAAP financial measures to the most directly comparable GAAP financial measures, as well as additional information about our reliance on non-GAAP financial measures. I will now turn the call over to Paul.

Thanks, Tripp. We ended 2025 with solid execution across our business, highlighted by fourth quarter revenue growth in both segments, strong gross margins, and continued operating expense discipline in cash management. In 2026, we're building on this momentum with a clear strategy to return to double-digit growth while maintaining our operational rigor and financial discipline. Before reviewing the quarter, I want to frame our discussion around the size and significance of the markets we serve and why we're confident in our long-term opportunity. Our flagship interventional technologies, Omni and TierCare, address two of the most prevalent anterior segment diseases, glaucoma and dry eye disease. Glaucoma remains the leading cause of irreversible blindness globally, and dry eye disease continues to be one of the most common reasons patients seek care from eye care providers. With proprietary, minimally invasive technologies designed to comprehensively address the root underlying causes of disease, we are expanding both the role of interventional solutions in the markets we serve and the markets themselves. Together, these two increasingly interventional categories offer substantial runway for continued growth in the years ahead. Consistent with that strategy, we've updated the way we describe our businesses. What we previously referred to as surgical glaucoma and dry eye, we now call interventional glaucoma and interventional dry eye, reflecting our focus on elevating the standards of care with earlier procedure-based interventions. We believe this interventional focus positions us to participate in an important part of the treatment continuum, and over time creates multiple durable growth drivers across both glaucoma and dry eye. We believe there is significant customer and patient overlap in these two categories that can unlock synergistic commercial value. Many patients who suffer from glaucoma also suffer from dry eye disease and meibomian gland dysfunction, which can be exacerbated by continued use of glaucoma medications, a known cause of ocular surface disease. In addition, many practices have dedicated eye care providers managing patients with both diseases, creating a natural synergy in care pathway and treatment. With strong collaboration between our interventional glaucoma and interventional dry eye teams, we have the potential to enhance our customer engagement, support adoption across both businesses and strengthen the scalability of our interventional eye care strategy with proven technologies experienced teams strong customer relationships and a track record of execution we believe we are well positioned to drive meaningful value as we continue building a leading interventional eye care company now turning to our segments i'll begin with interventional dry eye where we recently achieved a very important reimbursement milestone In the fourth quarter, 2MAX, Novitas Solutions, and First Coast Service Options established pricing for CPT code 0563T, the code associated with our care care procedure. This marks a turning point for our care care business model, and we are now executing our strategy with the goal of pioneering the reimbursed interventional dry eye treatment market. We were very encouraged by the commercial traction we generated with a variety of dry eye customers in the fourth quarter. As pre-announced in January, interventional dry eye revenue in the fourth quarter was $0.7 million, up both sequentially and compared to the prior year. Revenues were driven by the sale of approximately 700 smart lids to approximately 80 accounts, roughly 30 of which were new account engagements. The sequential and year-over-year revenue growth in the quarter was largely driven by sales in the Novitas and First Coast regions, where customer engagement with tier care has been strong and reflects positive momentum in the reimbursed business model. A portion of new customers are existing glaucoma customers of ours, who are excited to partner further on the tier care treatment opportunity. The increasing engagement across accounts as they establish their interventional dry eye practices and validate successful processing and payment of their first claims is promising. This progress is particularly notable given our small but growing sales team and the limited time since our reimbursed launch. As part of our commercialization strategy, we are focused on high-volume dry eye prescribers where TearCare presents a clear and compelling clinical and economic value proposition. In parallel, we are engaging new eye care providers in states where fee schedules have been newly established based on existing dry eye treatment activity, and we continue to expand our outreach to glaucoma customers in these markets, where TearCare is a natural complement to their current practice offerings. Early interest from new providers and renewed engagement from existing providers underscore for growing demand for tear care and interventional dry eye procedures. In order to scale this business and fuel growth, we are making additional investments in our interventional dry eye commercial organization. These investments are intended to strengthen provider engagement and expand commercialization in markets with established reimbursement. We added resources in the fourth quarter and will continue building out our commercial infrastructure to drive growth in 2026. Expanding market access also remains a critical pillar of our growth strategy. As we deepen our engagement with additional MACs and commercial payers throughout 2026, we believe we can accelerate adoption and expand access for patients. We have built a strong foundation on clinically differentiated technology, initial market access fee schedules, and early commercial validation, positioning us to pioneer the reimbursed interventional dry eye market for years to come. Turning to interventional glaucoma, the fourth quarter marked an important milestone in 2025, as we fully lapped the LCD changes, restricting multiple MIGS procedures in combination with cataract surgery. These LCDs reduced the number of devices used and caused meaningful headwinds to market growth in 2025. Despite these headwinds, our Omni technology once again demonstrated its importance in the glaucoma treatment paradigm in this single MIGS environment. In the fourth quarter, we built on our strong third quarter performance and generated another quarter of growth compared to the prior year. Revenue was $19.7 million, up 5% year-over-year, and flat sequentially, at the top end of our pre-announced revenue range provided in January. Ordering accounts increased 2% compared to the prior year, driven by a combination of reactivating accounts and adding new accounts. Utilization remained healthy, down only slightly after a particularly strong third quarter. Additionally, we saw continued benefit from higher Omni edge utilization, which drove higher average selling prices in the quarter. With the interventional mindset increasingly impacting the glaucoma treatment algorithm, we are focused on developing the standalone market with Omni. We are investing in targeted commercial resources to drive pseudophagic education and activation with surgeons and clinic staff. With similarities to the office-based cataract evaluation workflow that is familiar to most ophthalmic and optometric practices, we have designed an interventional glaucoma evaluation workflow that we believe represents a significant opportunity to expand omni-adoption in standalone interventions and support a meaningful source of revenue growth over time. In 2026, our interventional glaucoma strategy focuses on disciplined execution to drive share gains, expansion of the combo cataract segment, and further development of the underpenetrated standalone market. Driven by our experienced commercial team, clinically differentiated technology, and our investment in our dedicated pseudophagic market development team, we are positioned for a return to sustainable growth in interventional glaucoma. In closing, our strong fourth quarter performance reflects consistent execution across the organization and reinforces the momentum we are carrying into 2026. We believe we are well positioned to return to durable revenue growth in both segments as we leverage our differentiated technologies, experienced teams, and the synergies of these two opportunities to continue building a leading interventional eye care company. I will now turn the call over to Jim to discuss our financial results.

Thanks, Paul. before I turn to the results, I want to emphasize that we're entering 2026 from a position of strength. With the operating discipline and cost structure we need to support growth, and over time, we believe this positions us to achieve cash flow break-even without the need to raise additional equity capital. Unless otherwise noted, my comments reflect results for the fourth quarter of 2025, and comparisons are to the same period in the prior year. In the fourth quarter, total revenue was $20.4 million, a 7% increase. Interventional glaucoma revenue was $19.7 million, an increase of 5%, driven by increases in ordering accounts and average selling prices. Interventional dry eye revenue was $0.7 million, up from $0.3 million, reflecting positive traction in our reimbursed interventional dry eye business model. Gross margin was 87%, consistent with the prior year. Interventional glaucoma gross margin remained strong at 88%, compared to 87%, with the increase primarily due to higher average selling prices and product mix, slightly offset by tariff costs. Interventional dry eye gross margin improved to 68%, compared to 51%, primarily due to higher average selling prices. Total operating expenses were $21.5 million, a decrease of 25% compared to $28.5 million, primarily due to lower personnel-related expenses and stock-based compensation. As a reminder, we conducted a reduction in force in August 2025, and the fourth quarter was the first full quarter of our lower cost structure. Adjusted operating expenses were $18.9 million, a decrease of 23% compared to $24.4 million. Net loss was $4.2 million, or $0.08 per share, compared to a net loss of $11.8 million, or $0.23 per share. We ended the quarter with $92 million of cash and cash equivalents, compared to $120.4 million at the end of 2024. Cash usage was $0.4 million in the quarter, the lowest cash usage quarter of the year, reflecting continued operational discipline. We ended the year with $40 million of debt excluding unamortized discount and debt issuance costs unchanged from our 2024 year-end balance. Moving to our revenue outlook for full year 2026, we are initiating revenue guidance of $82 to $88 million, which reflects growth of 6% to 14% compared to 2025. This guidance includes revenue for our interventional glaucoma segment of $77 to $81 million, representing growth of 2% to 7%, and our interventional dry eye segment of 5 to 7 million, compared to 1.6 million in the prior year. This guidance reflects our philosophy of setting prudent targets and our focus on disciplined execution and the growth we believe we can deliver. Looking closer at the first quarter, we expect interventional glaucoma to grow low single digits compared to the first quarter of 2025. We expect the first quarter revenue to be the lowest quarter of the year in this segment and expect the second half of 2026 to be higher than the first half. Interventional dry eye revenue is expected to be approximately $1 million in the first quarter, and as we expand and scale our reimbursed tier care launch, we expect revenue to ramp throughout the year. We are also initiating our guidance expectations for full year 2026, adjusted operating expenses of $93 to $96 million, representing an increase of 6% to 9% compared to 2025. The expected increase is driven primarily by targeted market access and commercial investments in both interventional dry eye and interventional glaucoma. We're pleased with the operational and strategic progress achieved in the fourth quarter and throughout 2025. We remain focused on pioneering two significant categories in the interventional standalone glaucoma and reimbursed interventional dry eye markets. As we continue to execute against our long-term objectives, we're laying a strong foundation for sustainable growth and future success. Operator, please open the line for questions.

Thank you. And as a reminder to ask a question, simply press star 11 on your telephone and wait for your name to be announced. To remove yourself, press star 1-1 again. Our first question comes from the line of Frank Takinin with Lake Street Capital Markets. Please proceed.

Thank you for taking the questions, and congrats on a strong finish to the year. I was hoping to start with one on guidance. I'm just curious if you could provide some color on kind of low-end versus high-end assumptions, and it'd probably be helpful to talk about interventional glaucoma and interventional disease separately. Thank you.

Yeah, thanks, Frank. I can take that one. On interventional glaucoma, we're in a much more stable market and reimbursement environment than we saw a year ago. And we've got a couple of areas that we talked about in the prepared remarks where we're focused on there, expanding the combo cataract segment, as well as taking share there, and expanding the standalone market opportunity. So on the guidance there, in a much more stable market and stable environment, it's an area where we've been a leader in implant-free MIGs, and we've got a team that's had a proven track record of execution. And in a one-MIGs world, Omni performs quite well. So we feel good about getting back to growth here in 2026. On IDE, baked into that guidance, we're early. Q4 was a really critical milestone for us with the MACV schedules established. And you saw $0.7 million of revenue in the fourth quarter. As we look ahead to 2026, our initial guidance here, we want to set prudent guidance, and then really within that, we haven't assumed additional market access wins within our guidance, but the team is certainly heavily focused on market access initiatives and moving that forward here in 2026. So overall, I think we're excited about getting back to growth with both of our segments here getting to growth in 2026 and looking forward to executing here in 2026.

Perfect. And then a follow-up on kind of both of those factors. What are you assuming for underlying market growth in interventional glaucoma? And then saw the ASP a little bit over 1,000 for dry eye. Does that feel like a sustainable ASP rate, or is that maybe a little bit high for how we should be thinking about it?

Yeah, on the glaucoma market, Frank, we think it's in the low to mid-single-digit market growth there. And then, Allie?

Yeah, happy to take the ASP question. So remember, when you look at the IDE revenue, that includes a mix of smart lids sold as well as smart hubs sold. So, the ASP would be reflective of that mix within those segments. And we don't provide specific ASP information of our products, but that is certainly a factor that you should think about when you're building out your IDE model and considering the different components of revenue.

Got it. Thanks for taking the questions. Thanks, Rick.

Thank you. Our next question is from Danielle Antalfi with UBS. Please proceed.

Hey, good afternoon, guys. Thanks so much for taking the question. Sorry for my voice. I'm a little sick. Just a question on the standalone glaucoma market. I'm just curious what you see or how you see this evolving in the near term. I was at AO back in October. It seems to be very much a focus, and I'm a big believer in the standalone glaucoma market. But from a percentage penetration perspective, like how quickly can this ramp? And the second part of the question, what are the obstacles to getting there? And what are you guys doing to help break down some of those obstacles? Thanks so much.

Hi, Danielle. This is Paul. Happy to take that one. Yeah, it's an exciting time in interventional glaucoma for the past several years. site science as well as a handful of other industry players have been spending a lot of time working with our eye care provider partners in educating, educating the field on the benefits of earlier intervention with minimally invasive procedural based solutions for glaucoma. I think we're moving, we're excited to be making some targeted investments in activating the standalone market, so moving beyond an interventional mindset, moving beyond education. I think most glaucoma surgeons today do genuinely believe that intervening earlier with proven procedural interventions, whether that's a pharmaceutical or medical device, pure procedure, is better for patients over the long term. And now the goal is how to activate, how to turn that understanding of interventions being better earlier into actual cases. And we spent the last year at Sight Sciences really trying to understand how to activate the standalone opportunity. I talked about it a bit in the prepared remarks. We're modeling our standalone activation after something that's so well understood in ophthalmology. That's cataract surgery. Cataract surgery is a wonderful procedure. It's the number one procedure by volume in all of medicine. And there's a well understood patient workflow for cataract surgery. So a patient understands that they need to get cataract surgery. What happens next is they come back to their eye care provider for a dedicated visit to really understand what are the available cataract options. And then from there, they get a surgery scheduled. And we're finding in 2025, when we do that with a handful of accounts, when we bring, when we work with our providers to help them follow this workflow where they bring back a interventional glaucoma patient candidate for an interventional glaucoma dedicated consult, that consult results in a much higher level of procedural activation that activation might be omni it might be some other interventional procedure but if we if we do that well and our industry partners do that well and we convert this market from eyedrops to intervention whether that's omni or other procedures it's good it's good for patients it's good for providers and ultimately would be great for site sciences as well in terms In terms of percentages, I think, Danielle, your other question, we believe we estimate that the current MIGS market is approximately, like, in terms of revenue cases, maybe 90% combo cataract, 10% standalone. We believe we have a slightly higher percentage of mix of standalone. We estimate mid-80s combo cataract, mid-teens standalone. And we believe that mix for us is going to shift. Again, we've made some dedicated pseudophagic market development commercial investments, about a half a dozen market development focused professionals at Sight Sciences right now who are working across the country with our eye care providers and customers to activate the standalone market, to follow that interventional glaucoma consult playbook that we arrived that in 2025 and actually implementing it to drive standalone case volume. So, we're excited about it. It takes time to develop significant markets, but we believe that this will continue to be an area of growth for us over the years ahead.

Thank you so much.

Thanks.

Our next question comes from the line of Steve Lichtman with William Blair. Please proceed.

Thank you. Hi guys. I apologize for any background noise. I'm in the car. Congrats on the progress. I wanted to ask first actually on the operating expenses, you know, 4Q performance and the 2026 outlook were both better than our thinking. So as you think about this year, how are you balancing the opportunity you see on both sides of your business, but in particular on dry eye with keeping the level of spend in check? Are you focusing really on the two MAC areas for now in dry eye, any color there would be helpful.

Yeah, thanks, Steve. Hey, it's Jim. So as we look at investments in 2026, yeah, the bulk of them are on commercial infrastructure, and you nailed it. On our interventional dry eye, we're going to be placing investments in that space, and both on the market access side and driving market access progress, and then also on the commercial infrastructure side. So if and when we get additional market access wins, we're ready on the commercial side to drive traction. Our thinking is we want to have an eye on break-even and financial discipline like we've done over the past couple of years. We've proven we can really manage OPEX and manage spend. And now we're in a position with a strong balance sheet to go feel that growth. And we're going to invest. We're going to learn a lot and invest and potentially pivot quickly, but invest where it makes sense to go feel that growth in both dry eye as well as on the interventional glaucoma, particularly the standalone opportunity.

Yeah, just to add to that, I mean, we see the interventional dry eye opportunity as such a compelling large market opportunity and the early traction that we're seeing with accounts has validated that with us so the investments that we already have in commercial infrastructure appeared to be you know seeing good returns on those investments and we do expect to grow that team as we move forward both in the areas where we already have have uh fee schedules established and then also over time as we have additional reimbursement wins. So we are very excited about that, and that was something that we wanted to make sure we accounted for when putting out our operating expense.

Great, and then just double-clicking on that, in terms of the dry eye revenue for this year, it sounds like you're really laying out guidance essentially in those two MACs predominantly. And can you remind us, you know, obviously you're looking to get more wins, but just in those two max alone, what do you see the revenue opportunity is for dry eye?

Yeah, sure. So it's still an incredible opportunity just with those two max. They have 10.4 million covered lives. Our estimate, because there is a higher prevalence of dry eye disease in a Medicare-aged population, that there's about 700,000 patients in those markets with moderate to severe MGB. So still a very large market opportunity when you think about, you know, in Q4, we sold 700-ish smart lids. We're still at, you know, 0.1% of the market. So very early in terms of adoption per year, and when we think about guidance, even the revenue opportunity in those areas is quite significant. Our bigger constraint is our own commercial infrastructure and resources to go activate those accounts and work with customers to set up their interventional dry eye practices. So we do have a small team that is growing, but we also wanted to be careful to set prudent guidance, even taking into account the two states. So we won't be providing today kind of what's the full revenue opportunity of those markets, but it is quite compelling. And we think we've put guidance in a very prudent and reasonable place to start the year. And as we learn more and as we expand the team, we will provide updates.

Great. Thanks so much. Thanks, Steve.

Thank you. Our next question is from Tom Stefan with Stifo. Please proceed.

Thanks for taking the questions. First one on tier care, I know it's early and this may be a difficult question, but as coverage and reimbursement starts to take hold, can you talk to us a bit about sort of how you think about the peak sales potential of tier care, the inputs, the framework, et et cetera. And as a figure, I'll take a stab here, is a figure of at least $100 million a reasonable starting point as we think about tier care peak sales? And then I have a follow-up.

Yeah, thanks, Tom. I'll take that. So first of all, you know, obviously dry eye disease is a prevalent problem here in the United States. And if you look at the people who have moderate to severe MGD, there are 7 to 8 million people who suffer from dry eye disease. Obviously, tear care is a procedure that has been proven through the Sahara data to show real benefits to signs and symptoms of those patients with dry eye disease. And so we think it's a compelling opportunity for patients who need procedural intervention and want procedural intervention versus regular daily or multiple times a day drop. And so in terms of the opportunity from a market potential, it's obviously very large. What is critical in that is our ability to gain market access to patients being able to get interventional procedures using their insurance benefits. And obviously, we are still very early in the curve of adoption there with 10.4 million covered lives, and we do look to expand that over time to be able to really make procedural intervention a standard of care. In terms of your question of peak sales, we see this as a very large market opportunity. We aren't going to quantify that today, but you can very quickly do some math that shows this is an incredible opportunity for us from a revenue perspective, but more importantly, this is also an opportunity that is better for patients in terms of having a procedural intervention versus regular eye drops with proven clinical results. It's also better for the eye care providers because the eye care providers get to participate in economics since they are doing a procedural intervention versus drops where there's no incremental reimbursement for them. And we've also proven that it's better for the payers with our budget impact and cost utility analysis that shows that this is a better economic outcome for the payers as well. So we really think that this is a win for all. We're very, very early in terms of market adoption and penetration. So we aren't going to get out ahead of that today. But to us, this is one of the most compelling opportunities in eye care today.

And Tom, I would just add to that, obviously, we've spent a lot of time together in the MIGS category where you've got, you know, several thousand MIGS-trained surgeons, several thousand surgeons who are, you know, trained on Omni. In particular, when you think about the procedural dry eye opportunity, you know, not only are there more patients suffering from dry eye disease, but there's also many more eye care providers and customers that will be our customers for tear care across the country. That includes, obviously in surgery, it's just ophthalmology. In interventional dry eye, we have both the ophthalmic customers as well as the optometric customers. So there's thousands of ophthalmologists who can be customers for tier care. And there's many, many more optometrists who can be and will be customers for tier care. So that's another way to think about the TAM. We'll obviously prove it as we go. We're excited to prove it commercially and generate the traction and deliver the results quarter after quarter. But I think you're going to see a different kind of business model. One, because there's so many more patients. Two, there are so many more eye care providers. And lastly, the model becomes more interesting over time because unlike surgery and unlike MIGS, where the goal is a single treatment and hopefully that treatment keeps pressure under control for as many years as humanly possible, we know that's not the case with dry eye treatments, drop or procedure. And in this model, patients should stay in the model getting one to two treatments per So we think that the TAM is super interesting for all of those reasons.

Really appreciate the color. And then maybe to pivot to Glaucoma, and just on the first quarter outlook, up low single digit year over year, I would presume maybe is a bit below market, and it's against an easy comp. So can you talk a bit about just what you're seeing in the first quarter that supports that near-term view? anything we should be cognizant of from maybe a headwind standpoint that's driving that outlook? Thanks.

Hey Thomas, Jim, I'll take that one. I would say the only thing to really call out that's impacted us here in the first quarter as well as many others are the storms across the U.S. in January and February. um so that that's one piece otherwise we don't see any other any other meaningful things to call out here in the first quarter got it thanks everyone thank you our next question comes from adam major with piper sendler please proceed hi good afternoon thank you for taking the questions um two for me one on dry eye and one on interventional glaucoma um on dry eye

I was hoping just to get some additional color around your conversations that you're having with the other Macs as well as commercial payers, just trying to get a sense for when we could start to see some of those other payer dominoes fall. and would love just to better understand, you know, what exactly, you know, is – are they pushing back on anything? Maybe it's just a matter of time and bureaucracy, but you have 24-month randomized control trial data. So, you know, what do we kind of need to get those additional payers over the goal line? And then I had an additional question. Thanks.

Yeah, I'll take that one. And, you know, we've continued to be very active, engaging with the other MACs, having great conversations, discussing their own review processes of the clinical and economic data, as well as establishing pricing. And I will say that those conversations are continuing to progress. we do expect to have more MACs join and have more MACs establish fee schedules and we would expect that to happen this year so that's kind of our expectation you know more granularity it's always hard to predict exact timing with MACs but I will say that as you pointed out there is very strong clinical evidence and economic data and we are showing demand and interest from constituents in their market they are ECPs and patients are wanting access to this technology and because we do have these schedules already established in First Coast and Novotis that is creating heightened pressure on other Macs to also allow access to their Medicare beneficiaries to have have a fee schedule established so we are happy with the progress there again won't speculate on exactly who will be the next one to establish a fee schedule or when that will be, but I will say that those conversations have continued to move forward, and that's really what we expected.

Okay, fantastic. Thanks for all the color, Ali. And for the follow-up, I actually wanted to ask a reimbursement question on the glaucoma side. And, you know, I saw recently that AMA elected to move forward with the new Goniotomy codes with an effective date of January 2028. You know, so I guess what is SITE's expectation for kind of where reimbursement ultimately shakes out with those new codes? You know, can you level set us on the percentage of revenue tied to Goniotomy for your business? And, you know, how are you thinking about any potential impact, either positive or negative? Thanks for taking the questions.

Yeah, hi, Adam. Yeah, we are aware of the potential re-rock of goniotomy. We believe it's going to be the code will be split into an adult goniotomy code and a pediatric goniotomy code. pediatric goniotomy as you might expect is more intensive procedurally and has more follow-up requirements and so we would expect that the pediatric goniotomy economics might be you know maintained but the adult goniotomy when it's revalued everyone you know all experts in this area are saying they would expect it to be, unfortunately, reduced. If when that happens, it would be in effect January 2028, a fee reduction would obviously put pressure on the utilization of that procedure. OMNI, our flagship interventional glaucoma technology, it performs canaloplasty followed by trabeculotomy or aka goniotomy. It's billed either to canaloplasty or to goniotomy. We would expect if there's pressure on goniotomy alone as a procedure from an omni perspective as the leader in implant-free MIGs and the leader in ab interno canaloplasty, that that could actually be a tailwind at that time. Obviously, we believe hopefully the valuation of goniotomy is fair and reasonable. It's an important procedure in glaucoma. We hope that the assessment is acceptable to all stakeholders, mainly eye care providers. Thanks, Paul. Thanks, Paul. Sure.

Thank you.

Our next question comes from the line of david saxon with needham and company please proceed great uh good afternoon guys thanks for taking my questions um two for me one on uh both of the businesses first um just on the interventional dry eye i think you talked about in the script uh you're selling to some omni customers i think you in the past you've talked about something like 200 omni accounts in those to MAC region. So, just wanted to get an understanding, like, is this selling approach to ophthalmologists any different than what you would do with optometrists, either in terms of the length of the sales cycle or clinical education or any other dynamics like that?

Yeah, I'll take that. So, first of all, I'd say we're still very much in early days with this. So, the accounts that we're engaging with now truly are the early visionaries. They're the ones that are seeing procedural dry eye as a real opportunity for them, an important part of their procedure practices, and are looking to be leaders in this area. And so I do think that that profile of account is already different than what we'll see kind of at scale, especially with coverage density. Obviously, right now, it's a very targeted density associated with those accounts that have traditional fee-for-service Medicare beneficiaries, and so that also influences the accounts that are primary targets right now. So, right now, we are seeing a lot of synergies with ophthalmology practices that are existing interventional glaucoma accounts because they do have a high mix of medicare beneficiaries already and they have a lot of experience with a partnership with site sciences that said when we look at kind of our our revenue mix we are continuing to see you know new both a mix of new accounts and existing accounts order so both accounts that already believed in the benefits of procedural dry eye and uh you know had adopted the product in without reimbursement and then those that are now coming on board so I think it's too early for us to call out specific trends or dynamics here just because it is a unique market environment but we are very encouraged that our omni customers also have a serious problem with dry eye with within their patient population and they're looking for options to treat those so that has been a great synergy for us and one that we expect to continue to grow on in 2026.

Okay, thanks for that, Ali. And then on the IG business, looks like ordering facility count was down sequentially. Any color there? And then, you know, since you rolled out on the edge, you've been seeing a benefit from some pricing. I think you have Ultra, the next iteration coming out shortly. So, like, anything baked into the guide around kind of additional pricing uplift there? Thanks so much.

Thanks, David. On the utilization or account question, utilization has been fairly strong, and from Q3 to Q4, relatively flat. On the account side, we did have year-over-year growth, Q3 to Q4 down slightly, but Q3 was particularly strong in 2025. So as we look ahead, we continue to have a balance of reengaging accounts as well as adding new accounts. So our growth will come from a balance of accounts and adding new accounts as well as reengaging existing accounts and utilization at those. In terms of pricing, we did have some favorable pricing from EDGE in 2025, and as we look ahead to launching ULTRA here at some time in 2026, we don't have specific uplift baked in for ULTRA ASPs into the guidance. Great. Thanks so much.

This concludes our Q&A session. I will pass it back to Paul Badawi for his closing comments.

Thank you for attending today's call. We appreciate your interest in site sciences, and we look forward to updating you on our progress in the future.

And with that, we conclude our conference. Thank you for participating, and you may now disconnect.