AKBA · Akebia Therapeutics, Inc.
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AI Brief
Q2 FY26 earnings call · Aug 5, 2026TL;DR. Akebia reported strong sequential Vafseo revenue and patient growth, and announced a positive interim VOICE trial result for Vafseo versus ESAs on mortality/hospitalization, while guiding 2027 Vafseo revenue to decline on planned price cuts after loss of tadapa exclusivity; Auryxia revenue continued to fall, driving a quarterly net loss.
- + Vafseo Q2 net product revenue grew 34% sequentially to $21.3 million, with over 10,500 patients on therapy (a 41% sequential increase) and ~1,200 prescribers.
- + VOICE interim analysis met stopping criteria, showing Vafseo statistically superior to ESAs on the composite of all-cause mortality and hospitalization (win odds 1.16; p=0.0016).
- + Phase 2 basket trial of ebribafusp in IgA nephropathy, lupus nephritis, and C3 glomerulopathy initiated, with initial data expected in 2027.
- + Vafseo IP portfolio strengthened with a new Orange Book-listed patent and a potential 5-year term extension, with portfolio expirations out to 2036.
- − Q2 swung to a net loss of $8.9 million from net income of $0.2 million a year ago, driven by lower revenue and higher expenses including a $1.9 million restructuring charge.
- − Management expects 2027 Vafseo revenue to decline versus 2026 due to a planned price reduction after expected end of tadapa on December 31, 2026.
- − Auryxia revenue fell to $25.5 million from $47.2 million year-over-year and is expected to continue declining in 2026 due to generic competition and pricing pressure.
- − R&D expense rose to $14.1 million from $11.0 million year-over-year on higher clinical activity and headcount costs.
- − Total revenue declined to $49.1 million from $62.5 million year-over-year due to lower Auryxia revenue.
AI-generated from the earnings call and 8-K · may contain errors · not investment advice
Equibles Rating
blended score · not investment adviceBlended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.
Guidance & track record
Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.
Technicals
trend & momentum for long-term holders Strong SellIllustrative technical + ownership context — a signal mix, not investment advice.
Key metrics
Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.
Versus peers
Drug Manufacturers - Specialty & Generic — same industry group| Company | Mkt cap | YTD | Rev growth Y/Y | P/E | Short % shares |
|---|---|---|---|---|---|
|
AKBA
this stock
Akebia Therapeutics, Inc.
|
$244.05M | -45.9% | +47.5% | — | 7.4% |
|
TAK
Takeda Pharmaceutical Co Ltd
|
$60.23B | +14.6% | — | — | 0.1% |
|
GALDY
Galderma Group AG/ADR
|
$46.00B | -6.4% | — | — | 0.0% |
|
TEVA
Teva Pharmaceutical Industries Ltd
|
$45.67B | +26.0% | +4.3% | 64.3 | 2.7% |
|
HLN
Haleon plc
|
$40.72B | -13.7% | — | — | 0.5% |
Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding
At a glance
key data from every sectionPerformance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| AKBA | -5.2% | -11.1% | -37.8% | -5.3% | -45.9% |
| SPY | -0.4% | -0.2% | +12.4% | +0.2% | +12.0% |
| vs SPY | -4.8% | -11.0% | -50.2% | -5.5% | -57.9% |