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Crinetics Pharmaceuticals, Inc.
$42.03 -0.20 (-0.47%) At close · Jul 6
Market Cap
$4.43B
Shares
105,440,208

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$42.03 Open$42.03 Day$41.39–44.11 52W$25.83–57.99 Avg vol 30d1.3M Short int12.9M · 12.2% float · 13.2d Short vol57% Last earningsMay 7, 2026 DataJan 2020–Jul 2026 Filing10-Q · May 7
Equibles Rating blended score · not investment advice
Overall
Sell
Technical · trend & momentum Buy
50 / 200-day cross no cross
+ Price vs 200-day avg +0% above
+ Price vs 50-day avg +14% above
RSI (14) 71 · overbought
+ MACD trend positive
52-week position 50% · mid-range
Sentiment · smart money Bearish
Trend (MA cross) 50d $37 › 200d $42 — 200d above 50d
Institutional flow 3 of 244 funds reported for Jun 30 · net -16 sh shares
Insider flow Net -$3.4M over 90 days · 100% sells
Short interest 12.19% of float · ▲ +1.7% MoM · 13.2 days cover
Volume signal High volume on a down day — possible exhaustion
+ Institution breadth 244 holders — near 3-yr high, broad support
Fundamentals Weak
Revenue growth −74% Y/Y
EPS growth −34% Y/Y
Free cash flow $-383.7M
+ Balance sheet net cash $101.5M

Blended from price, positioning & fundamentals · daily-close · not investment advice.

Up next
Next earnings call
Aug 6, 2026 Est · unconfirmed · in 4 wks
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed May 7, 2026
AI Brief

TL;DR.

Bullish
    Bearish

      AI-generated from the earnings call and 8-K · may contain errors · not investment advice

      Guidance & track record
      Latest guidance · from the 8-K filed May 7, 2026
      Non-GAAP operating expenses · 2026 Non-GAAP Initiated $480M – $520M

      Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

      Technicals

      trend & momentum for long-term holders Buy
      1 · 2 · 3
      50 / 200-day cross
      no cross Neutral
      Price vs 200-day avg
      +0% above Bullish
      Price vs 50-day avg
      +14% above Bullish
      RSI (14)
      71 · overbought Bearish
      MACD trend
      positive Bullish
      52-week position
      50% · mid-range Neutral
      Market signals — smart money & positioning
      Bearish · 3 of 6
      Trend (MA cross) No cross
      50d $37 › 200d $42 — 200d above 50d
      Institutional flow Distributing
      3 of 244 funds reported for Jun 30 · net -16 sh shares
      Insider flow Distributing
      Net -$3.4M over 90 days · 100% sells
      Short interest Rising
      12.19% of float · ▲ +1.7% MoM · 13.2 days cover
      Volume signal Reversal watch
      High volume on a down day — possible exhaustion
      Institution breadth Multi-yr high
      244 holders — near 3-yr high, broad support
      Price context
      position in its 52-week range
      52-wk low $26 Now $42 · 50% 52-wk high $58
      vs 200-day avg +0% vs 50-day avg +14%

      Illustrative technical + ownership context — a signal mix, not investment advice.

      Key metrics

      the company's own KPIs, from its earnings releases, calls, and filings
      Metric Latest Period YoY
      Enrollment forms 232 Q1 2026
      Patients on reimbursed therapy 70% end of Q1 2026
      first quarter prescriptions from patients reinitiating therapy after discontinuing prior treatme 15% Q1 FY2026 call
      new patient enrollment forms 232 Q1 FY2026 call
      patients on therapy reimbursed 70% end of Q1 FY2026 call
      placebo-adjusted IGF-1 normalization (paltusotine) 79.7% PATHFNDR-1 analysis call
      treatment-naive patients share of total enrollments 15% Q1 FY2026 call
      unique prescribers 263 as of March 31 call
      Most prior authorization duration 12 Q4 FY2025
      U.S.-based open-label extension enrollment forms 22 Q4 FY2025

      Figures exactly as the company stated them · click a metric with a to chart its history · period links open the stating document · "call" marks figures stated on the earnings call, "filing" figures stated in the 10-K/10-Q · YoY needs the prior-year figure on file

      Versus peers

      Biotechnology — same industry group
      Open screener →
      Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
      CRNX
      Crinetics Pharmaceuticals, Inc.
      this stock
      $4.43B -9.7% -74.1% 12.2%
      AKTX
      Akari Therapeutics Plc
      $998.08B -5.7% 0.0%
      ONC
      BeOne Medicines Ltd.
      $488.96B +1.9% +22179.2% 995.1 0.1%
      VRTX
      Vertex Pharmaceuticals Inc / Ma
      $134.41B +16.8% +46.2% 31.4 1.8%
      REGN
      Regeneron Pharmaceuticals, Inc.
      $69.33B -15.7% +20.8% 16.1 3.2%

      Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

      At a glance

      key data from every section
      Ownership
      Institutional Holders Reducing
      Holders
      244
      % held
      112.2%
      Reported
      3 of 244
      Top holder
      FMR LLC
      Held Float
      View
      Held by Funds
      Fund positions
      315
      View
      Short & Settlement
      Short Interest Rising
      Shares short
      12.9M
      Days to cover
      13.2d
      Change
      +217.6K sh
      View
      Short Volume
      Short vol %
      57%
      As of
      Jul 6, 2026
      Short Total
      View
      Fails to Deliver
      FTD shares
      21.0K
      Value
      $735.4K
      As of
      Jun 10, 2026
      View
      Off-Exchange
      Off-exchange %
      46.7%
      Week of
      May 4, 2026
      Off-exch Lit
      View
      Smart Money
      Insider Trades Net selling
      Net (90d)
      -$3.4M
      Buyers / Sellers
      0 / 1
      Buyers Sellers
      View
      Congressional Trades Buy
      Member
      Gilbert Cisneros
      Amount
      $1.0K–$15.0K
      Traded
      Mar 3, 2026
      View
      Financials
      Financials
      Revenue (FY)
      $7.7M
      Net income (FY)
      $-465.3M
      EPS diluted
      $-4.95
      View
      Filings
      SEC Filings
      Latest
      8-K
      Filed
      Jul 6, 2026
      This year
      14
      View
      Proposed Sales
      Value
      $232.1K
      Shares
      6.0K
      Filed
      Jul 2, 2026
      View
      Exempt Offerings
      Offering
      $350.0M
      Filed
      Mar 11, 2024
      View
      Earnings & Events
      Earnings Calls
      Last call
      May 7, 2026
      View
      Investor Relations
      Latest news
      Vertex to Acquire Crinetics Pharm…
      Published
      Jul 6, 2026
      View

      Performance

      5D 20D 120D MTD YTD
      CRNX +14.5% +21.4% -21.1% +12.3% -9.7%
      SPY +3.1% -0.8% +8.2% +0.6% +10.2%
      vs SPY +11.5% +22.1% -29.3% +11.7% -19.9%
      Key facts CIK 1658247 CUSIP 22663K107 13F (30d) 5 filings 4 filers Visit website Investor relations