DTIL · Precision Biosciences Inc

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock.

The RSUs vest on the earlier to occur of (i) June 3, 2027 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock.

The RSUs vest on the earlier to occur of (i) June 3, 2027 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock.

The RSUs vest on the earlier to occur of (i) June 3, 2027 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock.

The RSUs vest on the earlier to occur of (i) June 3, 2027 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock.

The RSUs vest on the earlier to occur of (i) June 3, 2027 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

Award vests in three substantially equal annual installments beginning on February 19, 2027, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

Award vests in three substantially equal annual installments beginning on February 18, 2027, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

Award vests in three substantially equal annual installments beginning on February 19, 2027, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

Award vests in three substantially equal annual installments beginning on February 18, 2027, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on May 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On June 3, 2025 the Reporting person was granted RSUs. The RSUs vested on the earlier to occur of (i) June 3, 2026 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On June 3, 2025 the Reporting person was granted RSUs. The RSUs vested on the earlier to occur of (i) June 3, 2026 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On June 3, 2025 the Reporting person was granted RSUs. The RSUs vested on the earlier to occur of (i) June 3, 2026 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Represents the vesting of Restricted Stock Units ("RSUs") on May 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Represents the vesting of Restricted Stock Units ("RSUs") on May 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Represents the vesting of Restricted Stock Units ("RSUs") on May 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On June 3, 2025 the Reporting person was granted RSUs. The RSUs vested on the earlier to occur of (i) June 3, 2026 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On June 3, 2025 the Reporting person was granted RSUs. The RSUs vested on the earlier to occur of (i) June 3, 2026 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

Represents the vesting of Restricted Stock Units ("RSUs") on May 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on April 25, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on September 29, 2025. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on August 2, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on January 17, 2025. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

RSUs vests in three substantially equal annual installments beginning on February 17, 2026, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on February 17, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Represents the vesting of Restricted Stock Units ("RSUs") on February 17, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

RSUs vests in three substantially equal annual installments beginning on February 17, 2026, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on February 17, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

RSUs vests in three substantially equal annual installments beginning on February 17, 2026, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on February 17, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

RSUs vests in three substantially equal annual installments beginning on February 17, 2026, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on August 2, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.97 to $4.30. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote

The sales were effected pursuant to a Rule 10b5-1 plan adopted on April 25, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on January 17, 2025. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

The sales were effected pursuant to a Rule 10b5-1 plan adopted on September 29, 2025. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On January 20, 2023 the Reporting Person was granted RSUs, which vested in three substantially equal annual installments beginning on January 20, 2024, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Includes 3,413 shares acquired under the Issuer's 2019 Employee Stock Purchase Plan at a weighted average price per share of $5.74

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On January 20, 2023 the Reporting Person was granted RSUs, which vested in three substantially equal annual installments beginning on January 20, 2024, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On April 18, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On August 22, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On April 18, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On August 22, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

On April 18, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.