HOWL · Werewolf Therapeutics, Inc. · Holdings
Substantial doubt about the company's ability to continue as a going concern.
“We believe there is substantial doubt about our ability to continue as a going concern for at least twelve months from the date that these condensed consolidated financial statements are issued in this Quarterly Report. We are currently evaluating strategies to raise additional capital, however, there can be no assurances that we will be successful in mitigating the conditions which raise substantial doubt about our ability to continue as a going concern in the near term, if at all.”View the 10-Q filed Jul 31, 2026
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 46 13F filersWho Holds HOWL
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 45 filers, like-for-like change -22.4%; actively managed books -27.1%; index-like books -4.0%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 69.5% | 19 | -27.6% |
| Exempt adviser | 5.8% | 1 | 0.0% |
| Adviser | 0.7% | 1 | -93.4% |
| Bank | 6.9% | 6 | +34.6% |
| Broker-dealer | 0.1% | 2 | +15.1% |
| Non-US | 0.0% | 2 | +2.3% |
| Holding company | 1.4% | 4 | -18.1% |
| Insurer | 0.0% | 0 | — |
| Benefit plan | 0.0% | 0 | — |
| Unknown | 15.6% | 10 | +72.8% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 18.9% | 8 | -4.0% |
| Systematic-like | 21.9% | 9 | +744.5% |
| Concentrated | 28.7% | 6 | -60.7% |
| Diversified active | 25.1% | 21 | -11.1% |
| Unknown | 5.4% | 1 | 0.0% |
| Not measured | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 37.5% | 20 | -51.6% |
| Medium turnover | 22.0% | 9 | -25.0% |
| High turnover | 24.6% | 13 | +545.1% |
| Unknown | 15.9% | 3 | -12.9% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 20.0% | 7 | +6.8% |
| Medium horizon | 7.8% | 7 | -57.9% |
| Long horizon | 48.9% | 26 | -42.4% |
| Unknown | 23.3% | 5 | +245.5% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 21.6% | 8 | -6.2% |
| $1B to $10B | 4.6% | 13 | -64.8% |
| $10B to $100B | 46.6% | 7 | -30.9% |
| $100B or more | 27.2% | 17 | +7.0% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Individuals and high net worth | 0.7% | 7 | -10.7% |
| Pooled investment vehicles | 54.5% | 10 | -26.9% |
| Registered funds and BDCs | 14.3% | 2 | -7.8% |
| Pension and profit sharing plans | 0.0% | 0 | — |
| Insurance companies | 0.0% | 0 | — |
| Governments and sovereign funds | 0.0% | 0 | — |
| Diversified | 0.0% | 0 | — |
| Unknown | 30.5% | 26 | -19.8% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 38.2% | 10 | +60.2% |
| Venture capital funds | 22.0% | 1 | -64.3% |
| Mixed private funds | 0.0% | 0 | — |
| No private funds | 15.0% | 9 | -4.3% |
| Real estate funds | 0.0% | 0 | -100.0% |
| Other private funds | 0.0% | 0 | -100.0% |
| Private funds, type not stated | 0.0% | 0 | — |
| Securitized asset funds | 0.0% | 0 | — |
| Unknown | 24.7% | 25 | -8.6% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 89.4% | 38 | -26.7% |
| Outside the US | 10.6% | 7 | +52.3% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Conviction and Crowding
45 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).
Estimated Holder Cost Basis
Quarter ended Jun 30, 2026, on that quarter's share basisEstimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.
Estimated cost covers 81.9% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.
Shareholder Targets
13F filers that own its peers but not HOWL, quarter ended Jun 30, 2026Found through its holder-overlap peers: BIOA, TSHA, AVTX. 264 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | Avoro Capital Advisors LLC Registered adviser, Concentrated | $205,803,320 2 held | TSHA, AVTX |
| 2 | FMR LLC Holding company, Diversified active | $189,572,091 3 held | AVTX, TSHA, BIOA |
| 3 | Vestal Point Capital, LP Registered adviser, Diversified active | $146,538,150 2 held | TSHA, AVTX |
| 4 | Octagon Capital Advisors LP Registered adviser, Concentrated | $108,854,471 2 held | TSHA, BIOA |
| 5 | RTW INVESTMENTS, LP Registered adviser, Diversified active | $95,579,356 2 held | TSHA, AVTX |
| 6 | a16z Capital Management, L.L.C. Registered adviser, Concentrated | $79,244,996 1 held | BIOA |
| 7 | Siren, L.L.C. Unknown, Diversified active | $67,055,202 1 held | TSHA |
| 8 | Deep Track Capital, LP Adviser, Diversified active | $66,712,800 1 held | AVTX |
| 9 | Affinity Asset Advisors, LLC Registered adviser, Diversified active | $65,509,500 2 held | AVTX, TSHA |
| 10 | FARALLON CAPITAL MANAGEMENT LLC Registered adviser, Diversified active | $61,485,540 2 held | AVTX, TSHA |
Fund Ownership of HOWL by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 3.20% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 0.69% | 335,197 |
| Index ETFs | 2.51% | 1,217,976 |
| Active ETFs | 0.00% | 0 |
| Active funds | 0.00% | 653 |
| Unclassified | 0.00% | 0 |
| All registered funds | 3.20% | 1,553,826 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Large RA CAPITAL MANAGEMENT, L.P. Registered adviser | $859,587 | 21.23% | 2,387,744 | Shares | 2026-08-14 | |
| Large Balyasny Asset Management L.P. Registered adviser | $644,432 | 15.92% | 1,790,089 | Shares | 2026-08-14 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $438,471 | 10.83% | 1,217,976 | Shares | 2026-08-13 | |
| Large RENAISSANCE TECHNOLOGIES LLC Registered adviser | $242,867 | 6.00% | 674,632 | Shares | 2026-08-13 | |
| Small Lynx1 Capital Management LP Registered adviser | $236,802 | 5.85% | 657,786 | Shares | 2026-08-13 | |
| Small SPHERA FUNDS MANAGEMENT LTD. Exempt adviser | $225,651 | 5.57% | 626,810 | Shares | 2026-08-14 | |
| Micro DC Funds, LP | $212,076 | 5.24% | 589,102 | Shares | 2026-08-14 | |
| Small Verdad Advisers, LP | $125,535 | 3.10% | 348,709 | Shares | 2026-08-14 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC Registered adviser | $120,893 | 2.99% | 335,815 | Shares | 2026-08-12 | |
| Mega BANK OF AMERICA CORP /DE/ Bank | $112,140 | 2.77% | 311,502 | Shares | 2026-08-14 | |
| Mid XTX Topco Ltd | $97,732 | 2.41% | 271,478 | Shares | 2026-08-14 | |
| Mega JANE STREET GROUP, LLC | $90,661 | 2.24% | 251,837 | Shares | 2026-08-14 | |
| Mega UBS Group AG Bank | $77,700 | 1.92% | 215,838 | Shares | 2026-08-13 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $56,781 | 1.40% | 157,726 | Shares | 2026-08-13 | |
| Large Vontobel Holding Ltd. | $55,338 | 1.37% | 60,000 | Shares | 2026-10-16 | |
| Small Vilga Financial Planning LLC | $49,272 | 1.22% | 53,423 | Shares | 2026-10-09 | |
| Mega STATE STREET CORP Bank | $42,900 | 1.06% | 119,168 | Shares | 2026-09-22 | |
| Large Squarepoint Ops LLC Registered adviser | $37,167 | 0.92% | 103,242 | Shares | 2026-08-14 | |
| Mega BlackRock, Inc. Holding company | $36,566 | 0.90% | 101,573 | Shares | 2026-08-07 | |
| Small Rangeley Capital, LLC Registered adviser | $36,000 | 0.89% | 100,000 | Shares | 2026-08-14 | |
| Mega NORTHERN TRUST CORP Bank | $31,266 | 0.77% | 86,851 | Shares | 2026-08-13 | |
| Large Alyeska Investment Group, L.P. Registered adviser | $31,159 | 0.77% | 86,554 | Shares | 2026-08-14 | |
| Mid MPM BIOIMPACT LLC Adviser | $28,851 | 0.71% | 80,142 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $27,000 | 0.67% | 75,000 | Call | 2026-09-02 | |
| Mega MILLENNIUM MANAGEMENT LLC Registered adviser | $22,339 | 0.55% | 62,055 | Shares | 2026-08-14 | |
| Mid Virtu Financial LLC | $16,368 | 0.40% | 45,467 | Shares | 2026-08-13 | |
| Mega TWO SIGMA INVESTMENTS, LP Registered adviser | $9,828 | 0.24% | 27,300 | Shares | 2026-08-14 | |
| Mid GSA CAPITAL PARTNERS LLP Registered adviser | $9,772 | 0.24% | 27,146 | Shares | 2026-08-06 | |
| Mega GOLDMAN SACHS GROUP INC Holding company | $7,208 | 0.18% | 20,023 | Shares | 2026-08-14 | |
| Mid StoneX Group Inc. | $7,200 | 0.18% | 20,000 | Shares | 2026-08-12 | |
| Mega MORGAN STANLEY Holding company | $6,878 | 0.17% | 19,108 | Shares | 2026-08-13 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $5,580 | 0.14% | 15,500 | Put | 2026-09-02 | |
| Mid CERTUITY, LLC Registered adviser | $5,400 | 0.13% | 15,000 | Shares | 2026-07-28 | |
| Mega BARCLAYS PLC Bank | $4,764 | 0.12% | 13,235 | Shares | 2026-08-14 | |
| Mid HBK Sorce Advisory LLC Registered adviser | $4,761 | 0.12% | 13,227 | Shares | 2026-08-06 | |
| Mid Larson Financial Group LLC Registered adviser | $4,698 | 0.12% | 13,052 | Shares | 2026-08-14 | |
| Mega LPL Financial LLC Broker-dealer | $4,244 | 0.10% | 11,791 | Shares | 2026-08-07 | |
| Small Ranch Capital Advisors Inc. Registered adviser | $3,960 | 0.10% | 11,000 | Shares | 2026-08-03 | |
| Small Marest Capital, LLC Registered adviser | $3,913 | 0.10% | 10,870 | Shares | 2026-08-05 | |
| Large Cetera Investment Advisers Registered adviser | $3,672 | 0.09% | 10,200 | Shares | 2026-08-12 | |
| Mid Tower Research Capital LLC (TRC) | $3,562 | 0.09% | 9,897 | Shares | 2026-08-11 | |
| Large OSAIC HOLDINGS, INC. Holding company | $3,105 | 0.08% | 8,625 | Shares | 2026-08-14 | |
| Small Financial Perspectives, Inc Registered adviser | $2,430 | 0.06% | 6,750 | Shares | 2026-07-24 | |
| Mega JPMORGAN CHASE & CO Bank | $758 | 0.02% | 2,108 | Shares | 2026-08-12 | |
| Mid GROUP ONE TRADING LLC Broker-dealer | $673 | 0.02% | 1,871 | Shares | 2026-08-14 | |
| Mega BNP PARIBAS ARBITRAGE, SA Non-US | $284 | 0.01% | 790 | Shares | 2026-08-13 | |
| Mid SIMPLEX TRADING, LLC | $91 | 0.00% | 255 | Shares | 2026-08-12 | |
| Mid SBI Securities Co., Ltd. Non-US | $36 | 0.00% | 100 | Shares | 2026-07-23 | |
| Mid Optiver Holding B.V. | $7 | 0.00% | 22 | Shares | 2026-08-12 |