Good morning, and thank you for joining us to review NovoCure's fourth quarter and full year 2024 performance. I'm on the phone this morning with our Executive Chairman, Bill Doyle; CEO, Ashley Cordova; and our CFO, Christoph Brackmann. Other members of our executive leadership team will be available for Q&A. For your reference, slides accompanying this earnings release can be found on our website, www.novocure.com, on the Investor Relations page under quarterly reports. Before we start, I would like to remind you that our discussions during this conference call will include forward-looking statements, and actual results could differ materially from those projected in these statements. These statements involve a number of risks and uncertainties, some of which are beyond our control and are described from time to time in our SEC filings. We do not intend to update publicly any forward-looking statements, except as required by law. Where appropriate, we may refer to non-GAAP financial measures to evaluate our business, specifically adjusted EBITDA, a measure of earnings before interest, taxes, depreciation, amortization, and share-based compensation. We believe adjusted EBITDA is an important metric as it removes the impact of earnings attributable to our capital structure, tax rate, and material non-cash items, and best reflects the financial value generated by our business. Reconciliations of non-GAAP to GAAP financial measures are included in our press release, earnings slides, and in our Form 10-K filed with the SEC today. These materials can also be accessed from the Investor Relations page of our website. Following our prepared remarks today, we will open the line for your questions. I will now turn the call over to our Executive Chairman, Bill Doyle.

Thank you, Ingrid, and good morning, everyone. For 25 years, our mission at NovoCure has been to extend survival for patients with some of the most aggressive forms of cancer by developing and commercializing our novel therapy, tumor-treating fields. Prior to 2025, our commercial efforts focused largely on the treatment of glioblastoma. After achieving key milestones in 2024, FDA approval for the treatment of non-small cell lung cancer and successful Phase 3 readouts in pancreatic cancer and brain metastases from non-small cell lung cancer, 2025 is set to be a defining year for NovoCure as we move beyond a single indication to become a multi-indication oncology company. Our focus now is on execution and bringing TTFields therapy to many more patients in need. Entering 2024, we defined three clear objectives for our organization: grow our core GBM business, launch the non-small cell lung cancer indication, and deliver on the promise of our clinical pipeline. I am proud to report we achieved all of these objectives. In 2024, we generated $605 million in net revenue, growing our global active patient count to over 4,000. We received FDA PMA approval to treat second-line non-small cell lung cancer with a broad label and immediately began treating patients in the U.S. And we had two additional positive readouts from large randomized Phase 3 clinical trials: METIS in brain metastases from non-small cell lung cancer and PANOVA-3 for locally advanced pancreatic cancer. 2024 was a year of strong achievement at NovoCure and has set the stage for a pivotal year in 2025. In the 25 years since our founding, we have grown to a team of nearly 1,500 people, treated over 35,000 GBM patients, and are now poised to reach tens of thousands more with other difficult-to-treat cancers in the years to come. Our organizational evolution has included preparing to scale our operations to effectively reach these patients, while continuing to expand our approved indications. Last year, we announced that Ashley Cordova, our CFO, would succeed our founding CEO, Asaf Danziger, after his retirement in December, and Christoph Brackmann will be joining our team as the new CFO. 2025 marks the beginning of a new chapter for NovoCure as we build upon our strong foundation treating patients with GBM to begin to realize the full potential of the Tumor Treating Fields platform. I am pleased to turn the call to Ashley to provide more detail on our achievements in 2024 and our plans for 2025. Christoph will then review our fourth quarter and full year financial performance, after which we will take your questions.

Thank you, Bill. I am honored to step into the role of Chief Executive Officer at this pivotal moment in NovoCure's history. Our mission has never felt more urgent as we expand our reach to patients facing some of the most challenging tumors with significant unmet needs. To provide more detail on Bill's opening remarks, our first objective in 2024 was to grow our GBM business. GBM remains the foundation of our company, providing financial strength to invest in our pipeline and execute multiple launches. In 2024, we grew active patients by 10%, surpassing 4,000 active patients on therapy for the first time. Our growth was driven by strong performance in multiple markets, including France, now our third-largest market, and Germany and Japan. Improved US approval rates contributed to 2024 top line growth as higher US net pricing complemented the increase in global active patients. Our second goal in 2024 was to launch our newest indication, Optune Lua, in second-line non-small cell lung cancer. Entering the year, we submitted a PMA application to the FDA based on the LUNAR Phase 3 clinical trial data and began the process of building a thoracic sales force in anticipation of FDA approval. On October 15, we received FDA approval with a broad label, including both topotecan and physician's choice of immune checkpoint inhibitor as concomitant therapy options. Our Optune Lua sales team was immediately in the field, and between approval and year-end, we received 52 prescriptions, finishing the year with 20 active patients on therapy. We are pleased with these initial results, and the early feedback from patients and physicians is promising. Patients are eager to access a new unique therapy in non-small cell lung cancer, and we are seeing interest from thoracic oncologists, medical oncologists, and radiation oncologists regarding both concomitant chemotherapy and immunotherapy options. While early demand is promising, we remind investors that we are currently in the process of securing reimbursement, and these negotiations take time. We expect payer coverage milestones in 2025 with material revenue ramping in 2026 as coverage expands. Our final 2024 objective was to deliver on the promise of our clinical pipeline in indications with extremely high unmet need. In March, we announced successful top line results from our Phase 3 METIS trial investigating tumor treating fields therapy for the treatment of brain metastases from non-small cell lung cancer following stereotactic radiosurgery. METIS met its primary endpoint. Patients treated with tumor treating fields therapy exhibited 21.9 months median time to intracranial progression compared to 11.3 months for patients treated with supportive care. In December, we announced successful top line results from our Phase 3 PANOVA-3 trial, investigating tumor treating fields therapy together with gemcitabine and nab-paclitaxel for the treatment of unresectable locally advanced pancreatic cancer. PANOVA-3 also met its primary endpoint as patients randomized to receive tumor treating fields therapy demonstrated a median overall survival of 16.2 months compared to 14.2 months in the control arm. PANOVA-3 is the first and only Phase 3 trial to demonstrate a statistically significant survival benefit in this notoriously difficult-to-treat patient population. Early reactions from key pancreatic physicians have been very supportive, and we look forward to presenting the full data set at a medical conference later this year. METIS and PANOVA-3 represent major opportunities to expand our market reach as each serves patient populations with extremely high unmet needs. Brain metastases from non-small cell lung cancer and locally advanced pancreatic cancer, together with our recent lung cancer launch, have the potential to increase our eligible patient population to seven times our GBM opportunity. Beyond these near-term catalysts, we continue to invest in our pipeline in GBM, lung, and pancreatic cancers. With ongoing trials like TRIDENT, LUNAR-2, KEYNOTE-D58, and PANOVA-4, we see additional label expansion potential over the next few years. To touch quickly on these trials, our Phase 3 TRIDENT trial in GBM is studying the addition of tumor treating field therapy to chemoradiation rather than starting after chemoradiation, potentially increasing the duration and efficacy benefit of tumor treating fields. TRIDENT is fully enrolled, and we expect data in the first half of 2026. Our other pipeline trials are studying the concomitant use of tumor treating field therapy and immune checkpoint inhibitors, a regimen that showed promise in the LUNAR dataset. These trials include our Phase 3 LUNAR-2, our Phase 2 LUNAR-4, our Phase 3 KEYNOTE-D58, and our Phase 2 PANOVA-4 trial. The first three trials are open and enrolling. PANOVA-4 is fully enrolled, and we expect data in the first half of 2026. These trials represent the next wave of innovation in NovoCure’s clinical pipeline with the potential to significantly expand the use of tumor treating fields therapy in the cancers where we have already established clinical benefit. Beyond the progress made advancing our clinical pipeline, we achieved key milestones in our product development program with the approval of our HFE arrays in the US and Japan. The HFE arrays are thinner, lighter and more flexible than our legacy arrays. We are rolling out the HFE arrays in all major markets, and feedback has been very encouraging. We believe the rollout of our next-generation HFE array is an important step in improving patient usage, reducing barriers to adoption, and ultimately expanding the market for tumor treating field therapy. As we reflect on the progress achieved in 2024, the NovoCure story has substantially evolved. With the binary clinical events of prior years behind us, we are now focused on execution. 2025 is off to a strong start, and we expect to reach multiple important milestones this year. In lung cancer, we will continue to provide insights into the progress of our Optune Lua launch. We will pursue clinical guidelines and reimbursement in the US and regulatory approvals in Europe and Japan. In treating brain metastases, we expect to publish the METIS trial results and are engaged with the FDA in pre-submission discussions in anticipation of submitting a PMA application later this year. In pancreatic cancer, we expect to present the PANOVA data at an upcoming medical conference, followed by publication in a peer-reviewed journal. And again, we are engaged with the FDA in pre-submission discussions in anticipation of submitting a PMA application later this year. With FDA breakthrough designation for both brain metastases and pancreatic cancer, we have the potential for launches in both indications in 2026. 2025 marks the beginning of a new era in NovoCure's journey, as we evolve from one indication in GBM to a multi-indication platform therapy company. The vision is clear. We are working to extend survival for as many patients as possible as we build on an incredibly strong foundation. With that, I would like to turn the call over to our newest executive colleague, Christoph Brackmann.

Thank you, Ashley, and thank you all for joining us this morning. This is an incredibly exciting time for NovoCure, as we pivot from a single indication to a multi-indication company, and I feel very privileged to be joining NovoCure at this unique time. 2024 was a year of successful execution and growth. We generated revenues of $161 million in the fourth quarter of 2024, an increase of 21% compared to the same period in 2023, and $605 million for the full year, an increase of 19% year-over-year. This growth was primarily driven by our continued launch success in France, strong active patient growth in Germany and Japan, and significantly improved approval rates in the US, which are now reflected in our revenue baseline. Improved approval rates in the US resulted in $8.3 million of revenue from prior period claims during the quarter and $22.3 million for the full year. 2025 revenue growth is expected to closely reflect growth in Optune Gio active patients. As the GBM business reaches maturity, we expect to continue to grow at a low mid-single-digit rate this year. On the lung side, as Ashley explained earlier, our focus this year is on educating physicians, generating demand, and negotiating payer coverage. We anticipate meaningful revenue contribution starting in 2026 as coverage expands. Looking further ahead, we believe we have a clear path to address the patient population in multiple indications, which, taken together, is seven times larger than our GBM opportunity, and we are very focused on execution to reach these patients. Our gross margin in the fourth quarter was 79% and 77% for the full year 2024 compared to 75% in 2023. The improvement in gross margin is due to increased net revenue per patient, primarily attributed to our improved approval rates in the US. This year, we expect the global launch of the HFE arrays in the non-small cell lung cancer to be headwinds to gross margin. Regarding the ongoing global trade discussions, our global manufacturing supply chain networks allow for flexibility and capacity optimization. Based on current estimates, we do not foresee a material impact to margins in the short term, but we will continue to monitor this fluid situation closely. Sales and marketing expenses in the fourth quarter were $67 million and $239 million for the full year, reflecting increases of 14% and 5%, respectively, compared to prior year periods. G&A expenses in the fourth quarter were $72 million and $190 million for the full year, reflecting increases of 84% and 16%, respectively, primarily driven by stock-based compensation expenses related to the lung approval. Excluding stock-based compensation, G&A expenses for the full year were $10 million lower than 2023, driven by our 2023 restructuring efforts. Looking ahead, as our thoracic sales forces in the US and Germany are now fully staffed, we would expect some incremental expense primarily for marketing and in preparation for launch in additional countries. Research and development costs for the fourth quarter were $51 million, bringing the annual total to $210 million, decreases of 6% from both prior periods. We anticipate our R&D expenses to be roughly stable in 2025. Net loss for the fourth quarter was $66 million, or $0.61 per share. Net loss for the year was $169 million or $1.56 per share. Adjusted EBITDA for the fourth quarter was $3 million, an increase of $34 million from Q4 2023, and full year adjusted EBITDA was $1 million, an increase of $107 million compared to last year. This increase in adjusted EBITDA was driven by growth in net revenue, as well as disciplined management of operating expenses. While we continue to invest in growth opportunities, profitability remains an important goal at NovoCure and something we are actively driving towards. We anticipate generating positive adjusted EBITDA on a sustainable basis once we generate more material revenue from new indications. Cash and cash equivalents were $960 million as of December 31, 2024. As a reminder, we have a $561 million convertible note outstanding, which comes due in the fourth quarter. We believe the combination of cash on hand and funds available via our credit facility provides us with the necessary capital to pay the convertible note in full and fund operations for the foreseeable future. I would like to turn the call back to Ashley for closing comments.

Thank you, Christoph. To close, our vision is clear: we are striving to extend survival in some of the most aggressive forms of cancer. With the binary clinical events of prior years behind us, we are now focused on execution. This year marks the beginning of a new era in NovoCure's journey as we evolve from a single GBM indication into a multi-indication platform company. And if we look beyond the next two years, we are only scratching the surface of what Tumor Treating Fields therapy could afford patients. I'll now turn the call back to the operator for questions.

Thank you. Our first question comes from Jonathan Chang with Leerink Partners. Your line is now open.

Hi, guys. Thanks for taking my questions. Can you provide any more granularity on when and where we might see the PANOVA full data presentation? And can you provide any color on what we could learn when we get the full presentation versus the top line disclosure at the end of last year? Thank you.

Jonathan, this is Ashley. I'll start and then Nicolas can jump in with more granularity. But the short answer is, unfortunately, we can't provide information on when we will share the PANOVA-3 data. We're targeting all of the obvious conferences in the spring, but we'll be able to share more once we have confirmed acceptance.

Yes. Thank you, Ashley. This is Nicolas. Thank you, Jonathan, for that question. I don't have much to add to this. I mean, these are really important data, and we are thrilled to present them soon.

Thank you. Our next question comes from the line of Jason Bednar with Piper Sandler. Your line is now open.

Hello. Good morning. I wanted to start on the lung side. A lot of investor questions just around the trajectory of the lung launch after what was a pretty good start. I think a lot of us can agree in the fourth quarter, and I don't expect you to guide scripts or patients, but do you have targets on these metrics you would consider a success when we look at this year and next? And also, what does the trajectory look like in the U.S. here as we think about the cadence of 2025? And then if at all, I'm sorry, I'll layer on a few here, but can you talk about just the early experience of like patient compliance, doctors being repeat customers, the actual expansion of your doctor customer base in lung, anything there would be helpful.

Hi, Jason, this is Frank. Thank you for the questions. I'll start off in terms of talking about our objectives for the launch and how that maps out to volume growth. First, what we've said before is that we're really focused on getting the right physician with the right patient at the right time as our initial launch objective. And that's to take the learnings from GBM, we want to ensure a really strong positive first experience for the physician and patient, which then builds confidence for that next prescription and an expansion within that physician's practice. It also ensures that we have what I would say are really good cases to argue with the insurance companies as we move towards coverage. And that's really the second prong of our launch strategy, which is that we need to build up enough experience working with the payers that we eventually drive towards positive coverage policies with commercial payers and then turn that over into a positive Medicare coverage policy. So all that said, we don't, as you know, guide. But we are looking to build on the strong start and build up a sufficient volume of patients this year that we have those good relationships with practices and good interactions with payers. I think in terms of sort of anecdotes, you asked how the launch is going. I was at the Ilac Targeted Therapies conference last week and was really pleased to see that in the emerging therapy section, they had included Tumor Treating Fields along with all of the other new targeted therapies that are in Phase 2 and Phase 3 programs. And I think that's an early sign that the lung cancer community has gone from not knowing about Tumor Treating Fields to being skeptical of them perhaps at the first release to now saying, okay, let’s understand this data in the context of the emerging landscape of treatment of lung cancer. So we've been really pleased on that front, and I am happy to add additional color if there are different areas you'd like me to go into.

That's helpful, Frank. I do appreciate it. Maybe one follow-up just since you kind of opened the door a little bit on the payer side. Just I think Ashley mentioned in her prepared remarks that we should have coverage wins that start to occur this year. Just how are those discussions going? Can you talk about maybe the pacing of when you expect we'll see these? What are these payers actually looking at, the sides, just data? And then within that context, can you also talk about whether you expect commercial payers and Medicare to establish new codes or to utilize existing codes from GBM when adding non-small cell lung? Thank you.

It's still early to provide details on payer interactions since we're discussing the initial 20-patient cohort. However, I can share that it has exceeded our expectations thus far, and we believe we're making good progress with the payers. Their primary focus aligns with what physicians prioritize, which is addressing the significant unmet need for treatment in the second line for Stage 4 non-small cell lung cancer. This is a strong starting point for discussions with payers. Consistently, we've indicated that we expect it will take around one to two years for commercial payers to develop coverage policies, with Medicare likely trailing by about a year, and we still hold to that timeline.

The only other thing I would add is this is the beauty of having a multi-indication platform is we get to leverage our experience and the knowledge that we built up in GBM directly into the lung cancer indication. So this is a process we know how to do, and we're doing it with the same team that has successfully executed in GBM.

Thanks. Sorry. Anything on the coding?

That's right. Thank you, Jason. Regarding the codes, we expect to continue using the same code.

Thank you. Our next question comes from the line of Larry Biegelsen with Wells Fargo. Your line is now open.

Good morning. It's Lei calling in for Larry. Thanks for taking my question. Just first, on this call so far, you mentioned several times about improved U.S. approval rates that contribute to revenue in 2024. Can you give any more color on how much that improvement was as far as revenue or revenue growth, and if we could see that improve further in 2025? And related to that, in 2024, you had some benefits from collections in the U.S. revenue. Any thoughts on how we should think about in 2025? I guess, really looking at it from a bigger picture perspective, is there anything the Street might be missing on either those points or any other factors? And I have a follow-up.

Yes. Thank you for the question. This is Christoph. So, happy to provide some color on this. Growth in 2024 in total from improved approval rates was $42 million, driven by the U.S. Now, $22 million of that was from prior periods, so sort of a one-off windfall that we had in the prior year. Going forward, we do not comment on the exact level of approval rates, but it is at a level where we believe there is not much room for improvement. Hence, we do not expect similar impacts going forward. And that's what we said in the prepared remarks. We expect the growth to be in line with Optune Gio active patients growth. I think that probably answers your question.

And we do think this is fairly well reflected in the model.

Thank you for the information. For my follow-up, I would like to ask about the METIS and PANOVA publication. Should we anticipate these in 2025 or 2026? Also, you mentioned filings for both later this year, which seems a bit later than we had anticipated. Are you being cautious in your approach? Is there anything we should consider regarding the process? Thank you once again for addressing my questions.

Yes. No, I think I'll start there. So, the short answer is, yes, you should expect publication this year in the process of finalizing these submissions. We're finalizing the manuscript, and they'll go in. We are in the process of having active pre-submission discussions with the FDA. We have breakthrough device designation on both of these indications, which provides us the opportunity to go back and forth with some interactive review questions prior to the formal filing, and we're in that process right now. So, I wouldn't read anything into timing other than the fact that we're in that kind of pre-submission process right now, and we'll move it through to filing as soon as possible. But this process probably will go slow to go fast, and we're in the interactive review part of the process right now. I do think it's important why we talk about the milestones to ground everybody though, in the data and the Total Addressable Market (TAM), right? These are both indications where we have a significant unmet need that is the first advance ever for these specific populations, reflected in the breakthrough device designation. Both of these provide a TAM expansion opportunity that is a multiple of what we have in GBM. As you look at the three in aggregate, you've heard us say many times before, seven times the GBM opportunity. So, we are as eager to get these in markets as you all are to have us have them in market because it is a real transformative opportunity for the company.

Thank you. Our next question comes from the line of Vijay Kumar with Evercore ISI. Your line is now open.

Hey, guys. Good morning. Thanks for taking my question. My first one was on the lung side, 52 prescriptions in that Q4. Should we model a sequential step up throughout the year when you look at that 52 starting point and 20 active patients? And any goalpost on what percentage of covered lives should we expect to have some sort of coverage by end of 2025, end of 2026, et cetera?

Yes. It's probably too soon for us to give you specific numbers, Vijay. You'll see a track out. What we'll say is that certainly, you should expect it to grow throughout the course of the year. This is a launch, right? So you would expect these numbers to trend up. In terms of pace, what we will say is we're pleased, and it's in line with expectation, but it is focused on the right patient at the right time. Similarly with the payer, we'll let you know as soon as we have enough track record to give you an anchor number, but we're not there yet. We would expect to exit 2025 with substantial experience to drive revenue in 2026. And then, Frank, anything you can add?

Yes, Vijay, thanks for the question. I'd just add in terms of color on the launch, what we're really looking at right now is the interactions we're having with our physicians and the patient profiles that are coming in. What we're pleased with is that we're seeing patients getting Tumor Treating Fields plus immune checkpoint inhibitors, which to us is a good sign because we know that's a robust market.

Understood. And sorry, just when you make the comments substantial revenues in 2026, safe to assume at least a quarter of covered lives are under some sort of coverage exiting 2025. Would that be a sensible assumption?

Yes. Unfortunately, we're not going to be able to give you an anchor number. What we have said in the past is that commercial will come first. We expect that to work through the system in 2025, and commercial is about 25% of the non-small cell lung cancer opportunity. So those are statements you can consider.

Understood. Then a couple of P&L questions, one on China. Q4 revenues declined sequentially. Was that a timing element? Maybe talk about what's happening in China?

I'd say that has more to do with the ending of the amortization of the royalty. Let me remind everybody that that China number includes both their purchases for future product and the royalty on sales and the amortization of other royalties in that agreement. I would say it's largely driven by timing and purchases and the roll-off of the amortization.

Sorry. So when you look forward, is the fiscal 2024 revenue base for China, should that grow? Or is that like flattish or should that be down?

What I will say is you should look at Q4 as the baseline that doesn't include the royalty, so that's a good baseline, and then I would kick it back to you to answer their expectations about growth.

Understood. And then maybe one on margins for cash flow. I think you mentioned gross margin should be down for fiscal 2025, given the new launches. Can you quantify that? I think related, you said OpEx to step up. Is the step-up in OpEx, should that be in line with revenues or above revenues? And what are the implications of free cash flows if gross margins are down and OpEx are stepping up?

Yes. Regarding the gross margin, it was 79% for the quarter and 77% for the year, benefiting from increased approval rates and prior period claims, which contributed $22 million for the full year. If adjusted, the gross margins would be in the mid-70s, which serves as a solid reference. Looking ahead to 2025, we anticipate challenges for the gross margin from two aspects. First, the introduction of the new head array, which is lighter, thinner, and more flexible, offers significant advantages for patients but comes at a higher cost, leading to a gross margin headwind as we roll it out in the US. Second, there will be another difficulty on the lung side as we take on risk and negotiate payer coverage, impacting the gross margin. In summary, we expect the gross margin to trend closer to the lower 70s temporarily, after which we anticipate a rebound. On the expense front, during this launch phase, we foresee some additional costs, particularly related to sales and marketing, while general and administrative expenses will remain stable.

But I would just reiterate that we feel confident that we have the financial strength and the cash balance that we need to get through these growth periods.

Understood. Thanks guys.

Thank you. Our next question comes from the line of Jessica Fye with JPMorgan. Your line is open.

Hey, good morning, guys. This is Tanmay on for Jess. Could you talk about what's the current number of active patients on Optune for lung cancer in the US? And how does it compare to the 20 active patients you reported at the end of 2024? And also, maybe a comment on what factors do you think are driving or hindering that patient adoption here? Thank you.

I cannot provide specifics about our progress during the quarter, so I can't discuss any changes in the number of patients since the 20 we reported at year-end. However, I can share an experience I recently had with two physicians who are now treating multiple indications with Novocure and tumor treating fields. They have successfully treated patients with glioblastoma and participated in our medical oncology trials for PANOVA and LUNAR. These physicians currently have patients undergoing treatment for lung cancer as well as others in clinical trials for glioblastoma and other indications. We're starting to see the advantages of being a multi-indication company, which is quite exciting for us.

Great. And maybe if I can squeeze in one more, how do you think about the drivers for revenue growth in 2025? Maybe a comment on that would be really helpful. Thank you.

Yeah. I would say 2025 is really going to be a kind of demand-generation year, which will unlock material revenue contributions in 2026. This revenue will come principally from the lung cancer indication. Again, we've reminded everybody that GBM is a solid foundation that funds our investments in R&D, but that the real unlock in growth will come from launches in lung. As we look ahead in 2026, we'll layer on PANOVA with those launches. 2025 is the demand generation year.

Thank you. And I'm currently showing no further questions at this time. I'd like to hand the call back over to Bill Doyle for closing remarks.

So I'd like to conclude this call, as I always do, by first thanking all of our NovoCure colleagues for their hard work and their dedication to our patients. And I'd like to thank you for your continued interest in NovoCure. This is actually my 36th earnings call since our IPO in 2015, and I believe it marks a true pivot, a true moment in the history of this company. As I was reflecting on the script, as we were editing it and putting it together, this next chapter, as we move and grow from our foundation in GBM to a global multi-indication cancer company is something I think that all of us should be proud of and excited for as we continue to pursue our mission to help patients extend their survival with some of the most aggressive forms of cancer. So thank you.

This concludes today's conference call. Thank you for your participation. You may now disconnect.