APRE · Aprea Therapeutics, Inc. · Holdings

$0.55 +0.02 (+3.14%)

Market Cap

$6.56M

12.59M

Volume · Oct 20 366.85K Avg daily vol (3M) 288.61K

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP → See every holder of APRE: 13F, 13D and 13G, insiders and funds →

Institutional holdings are being reconciled with SEC filings. Holder totals and changes may be incomplete until reconciliation finishes.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 28

Total Value: $1,901,405

Total Shares: 2,370,849

Institutional Ownership Trend

27 quarters

Holder Concentration

Across 27 13F filers

Top Holder

42.8%

of institutional value

Top 5

82.1%

of institutional value

Top 10

93.2%

of institutional value

HHI

2,310

Moderately concentrated

Who Holds APRE

Last 8 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 27 filers, like-for-like change +5.6%; actively managed books +7.4%; index-like books -12.1%.

Holder type	Share	Filers	Change	New	Exited
Registered adviser	37.0%	9	+19.5%	2	0
Exempt adviser	11.9%	2	+4.3%	1	0
Bank	0.6%	3	+558.7%	2	0
Broker-dealer	0.7%	2	-23.1%	0	0
Non-US	1.9%	2	+13.5%	0	0
Holding company	1.4%	4	+7.1%	1	0
Adviser	0.0%	0	—	0	0
Unknown	46.5%	5	-3.7%	1	2

Style	Share	Filers	Change	New	Exited
Index-like	7.7%	6	-12.1%	1	0
Systematic-like	3.1%	4	+281.9%	2	1
Concentrated	44.7%	3	+4.4%	1	0
Diversified active	44.5%	14	+5.3%	3	1
Not measured	0.0%	0	—	0	0
Unknown	0.0%	0	—	0	0

Turnover	Share	Filers	Change	New	Exited
Low turnover	6.4%	10	-18.0%	2	0
Medium turnover	26.5%	6	+15.6%	1	0
High turnover	64.5%	9	+4.9%	4	2
Unknown	2.6%	2	+5.6%	0	0
Not measured	0.0%	0	—	0	0

Holding horizon	Share	Filers	Change	New	Exited
Short horizon	48.2%	6	+0.9%	3	1
Medium horizon	15.1%	4	-0.4%	0	0
Long horizon	16.6%	14	+50.2%	4	0
Unknown	20.1%	3	-2.8%	0	1
Not measured	0.0%	0	—	0	0

13F book size	Share	Filers	Change	New	Exited
Under $1B	13.8%	4	-1.2%	2	1
$1B to $10B	66.9%	7	-0.3%	1	1
$10B to $100B	5.1%	3	+205.6%	0	0
$100B or more	14.3%	13	+19.1%	4	0
Not measured	0.0%	0	—	0	0

Client base	Share	Filers	Change	New	Exited
Individuals and high net worth	0.6%	2	0.0%	0	0
Pooled investment vehicles	32.3%	5	+31.7%	2	0
Registered funds and BDCs	4.1%	2	-29.6%	0	0
Other	0.0%	0	—	0	0
Unknown	63.0%	18	-1.1%	5	2

Private funds	Share	Filers	Change	New	Exited
Hedge funds	44.1%	7	+23.0%	3	0
Other private funds	0.6%	1	0.0%	0	0
No private funds	4.1%	3	-29.5%	0	0
Private funds, type not stated	0.0%	0	—	0	0
Unknown	51.1%	16	-2.3%	4	2

Location	Share	Filers	Change	New	Exited
United States	87.7%	21	+5.4%	4	2
Outside the US	12.3%	6	+7.5%	3	0

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Conviction and Crowding

27 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders

0.000% of filers hold it in their top 10

Mar 31, 2026: 0

Holders above 5%

median weight 0.000%

Mar 31, 2026: 0

Crowding

17.2%

of shares outstanding, 50th percentile

Mar 31, 2026: 17.2%

Private-fund advisers

8.56%

of shares outstanding

Institutional ownership

19.1%

20.5% of the estimated free float

Top 10 holders

93.2%

of 13F shares, Herfindahl 0.231

Active holders

+7.4%

like-for-like share change of active filers

5% stakes on record

0 13D, 3 13G (3 institutional, 0 passive, 0 exempt)

How long holders have held it value-weighted 9.5 quarters

Under 1 year 29.2% 1 to 3 years 23.5% 3 years or more 47.3% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost

$3.07

estimated per share

Mar 31, 2026: $3.36

Quarter-end price

$0.80

implied by 13F values

Estimated gain or loss

-73.9%

price against the estimated cost

Estimated at a loss

72.2%

of costed 13F value

Estimated cost covers 53.0% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies APRE's active holders also own, quarter ended Jun 30, 2026

#	Company	Shared holders	Similarity
1	VYGR Voyager Therapeutics, Inc.	3	0.474
2	TSHA Taysha Gene Therapies, Inc.	3	0.250
3	ELVN Enliven Therapeutics, Inc.	3	0.212
4	BMRN Biomarin Pharmaceutical Inc	3	0.183
5	RVMD Revolution Medicines, Inc.	3	0.121

Shareholder Targets

13F filers that own its peers but not APRE, quarter ended Jun 30, 2026

Found through its holder-overlap peers: VYGR, TSHA, ELVN, BMRN, RVMD. 956 filers in all.

#	Filer	In peers	Of book	Largest peers
1	FARALLON CAPITAL MANAGEMENT LLC Registered adviser, Diversified active	$2,553,115,574 2 held	15.1%	RVMD, TSHA
2	BAKER BROS. ADVISORS LP Registered adviser, Concentrated	$2,216,322,729 3 held	11.2%	RVMD, ELVN, TSHA
3	VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser, Diversified active	$2,101,116,800 5 held	0.090%	RVMD, BMRN, ELVN
4	Jupiter Topco LLC Unknown, Diversified active	$2,085,006,398 4 held	0.850%	RVMD, BMRN, ELVN
5	Darwin Global Management, Ltd. Exempt adviser, Concentrated	$1,990,753,064 1 held	51.4%	RVMD
6	STATE STREET CORP Bank, Index-like	$1,506,632,348 5 held	0.040%	RVMD, BMRN, TSHA
7	Nextech Invest, Ltd. Exempt adviser, Concentrated	$1,423,531,573 1 held	67.8%	RVMD
8	Paradigm Biocapital Advisors LP Registered adviser, Concentrated	$1,191,348,571 1 held	25.9%	RVMD
9	NORGES BANK Non-US, Index-like	$888,922,610 3 held	0.090%	BMRN, RVMD, TSHA
10	Dodge & Cox Registered adviser, Diversified active	$849,426,894 1 held	0.440%	BMRN

Fund Ownership of APRE by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 0.92% of shares outstanding.

Fund type	Of shares outstanding	Change	Shares	Funds
Index funds	0.76%	+0.08 pp	96,073	4
Index ETFs	0.16%	0.00 pp	19,622	1
Active ETFs	0.00%	0.00 pp	0	0
Active funds	0.00%	0.00 pp	289	1
Unclassified	0.00%	0.00 pp	0	0
All registered funds	0.92%	+0.08 pp	115,984	6

How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Holder type: Registered adviser 9 Exempt adviser 2 Bank 3 Broker-dealer 2 Non-US 2 Holding company 4 Unknown 6

Showing 28 of 28

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

AIGH Capital Management LLC

$814,463

42.83%

1,015,541

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Worth Venture Partners, LLC	100,297	$80,438	9.9%	Other
Held directly	915,244	$734,025	90.1%	Sole

Vestal Point Capital, LP

$280,700

14.76%

350,000

SPHERA FUNDS MANAGEMENT LTD.

$216,540

11.39%

270,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	270,000	$216,540	100.0%	Defined

Nantahala Capital Management, LLC

$165,019

8.68%

205,760

RENAISSANCE TECHNOLOGIES LLC

$84,851

4.46%

105,800

GEODE CAPITAL MANAGEMENT, LLC

$60,044

3.16%

74,869

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	1,862	$1,493	2.5%	Defined
Held directly	73,007	$58,551	97.5%	Defined

CITADEL ADVISORS LLC

$46,997

2.47%

58,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	58,600	$46,997	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$36,259

1.91%

45,211

DIADEMA PARTNERS LP

$36,015

1.89%

44,907

VANGUARD FIDUCIARY TRUST CO

$30,848

1.62%

38,464

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$28,021

1.47%

34,939

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
G1 EXECUTION SERVICES, LLC	34,939	$28,021	100.0%	Other

MORGAN STANLEY

$20,715

1.09%

25,830

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY CAPITAL SERVICES, LLC	25,750	$20,651	99.7%	Defined
MORGAN STANLEY SMITH BARNEY LLC	80	$64	0.3%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$18,351

0.97%

22,882

LPL Financial LLC

$12,873

0.68%

16,052

HighTower Advisors, LLC

$11,118

0.58%

13,864

NORTHERN TRUST CORP

$10,991

0.58%

13,705

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	13,705	$10,991	100.0%	Defined

Persistent Asset Partners Ltd

$9,214

0.48%

11,490

XTX Topco Ltd

$8,473

0.45%

10,565

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	10,565	$8,473	100.0%	Defined

BlackRock, Inc.

$5,751

0.30%

7,173

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	71	$56	1.0%	Sole
BlackRock Fund Advisors	289	$231	4.0%	Sole
BlackRock Institutional Trust Company, N.A.	6,813	$5,464	95.0%	Sole

Tower Research Capital LLC (TRC)

$2,879

0.15%

3,590

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	3,590	$2,879	100.0%	Defined

GROUP ONE TRADING LLC

$462

0.02%

577

BARCLAYS PLC

$379

0.02%

473

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS CAPITAL INC.	473	$379	100.0%	Defined

OSAIC HOLDINGS, INC.

$236

0.01%

295

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	295	$236	100.0%	Defined

WealthCollab, LLC

$126

0.01%

158

FMR LLC

$36

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STRATEGIC ADVISERS LLC	45	$36	100.0%	Defined

TD Waterhouse Canada Inc.

$30

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TORONTO DOMINION BANK	40	$30	100.0%	Defined

SBI Securities Co., Ltd.

$12

0.00%

UBS Group AG

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	3	$2	100.0%	Defined

Key facts CIK 1781983 CUSIP 03836J201 13F (30d) 1 filings 1 filers Visit website Investor relations