APRE · Aprea Therapeutics, Inc.

$0.81 -0.03 (-3.08%)

Market Cap

$10.07M

12.59M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 28

Total Value: $1,901,411

Total Shares: 2,370,855

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 28 13F filers · Δ vs Mar 31, 2026

Top Holder

42.8%

−2.4 pts

Top 5

82.1%

−5.2 pts

Top 10

93.2%

−2.5 pts

HHI

2,310

Moderately concentrated−257

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +6

Institutional value: +11.0%

Shares held: +5.6%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large RENAISSANCE TECHNOLOGIES LLC	+80,700	105,800
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP	+21,921	34,939
Mega BNP PARIBAS ARBITRAGE, SA	+5,394	45,211
Mega MORGAN STANLEY	+3,500	25,830
Mega VANGUARD CAPITAL MANAGEMENT LLC	+3,260	22,882

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega GEODE CAPITAL MANAGEMENT, LLC	−44,262	74,869
Mega LPL Financial LLC	−5,000	16,052
Mega UBS Group AG	−2,150	3
Mid Tower Research Capital LLC (TRC)	−1,537	3,590
Mega BlackRock, Inc.	−1,331	7,173

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega CITADEL ADVISORS LLC	58,600	$46,997
Small DIADEMA PARTNERS LP	44,907	$36,015
Mega NORTHERN TRUST CORP	13,705	$10,991
Small Persistent Asset Partners Ltd	11,490	$9,214
Mid XTX Topco Ltd	10,565	$8,473

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)	Open
Small Scientech Research LLC	60,281	$45,994
Small TWO SIGMA SECURITIES, LLC	13,500	$10,300

Filter: New 8 Increased 5 Reduced 5 Sold out 2 Unchanged 10

Showing 28 of 28

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

AIGH Capital Management LLC

$814,463

42.83%

1,015,541

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Worth Venture Partners, LLC	100,297	$80,438	9.9%	Other
Held directly	915,244	$734,025	90.1%	Sole

Vestal Point Capital, LP

$280,700

14.76%

350,000

SPHERA FUNDS MANAGEMENT LTD.

$216,540

11.39%

270,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	270,000	$216,540	100.0%	Defined

Nantahala Capital Management, LLC

$165,019

8.68%

205,760

RENAISSANCE TECHNOLOGIES LLC

$84,851

4.46%

105,800

GEODE CAPITAL MANAGEMENT, LLC

$60,044

3.16%

74,869

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	1,862	$1,493	2.5%	Defined
Held directly	73,007	$58,551	97.5%	Defined

CITADEL ADVISORS LLC

$46,997

2.47%

58,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	58,600	$46,997	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$36,259

1.91%

45,211

DIADEMA PARTNERS LP

$36,015

1.89%

44,907

VANGUARD FIDUCIARY TRUST CO

$30,848

1.62%

38,464

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$28,021

1.47%

34,939

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
G1 EXECUTION SERVICES, LLC	34,939	$28,021	100.0%	Other

MORGAN STANLEY

$20,715

1.09%

25,830

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY CAPITAL SERVICES, LLC	25,750	$20,651	99.7%	Defined
MORGAN STANLEY SMITH BARNEY LLC	80	$64	0.3%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$18,351

0.97%

22,882

LPL Financial LLC

$12,873

0.68%

16,052

HighTower Advisors, LLC

$11,118

0.58%

13,864

NORTHERN TRUST CORP

$10,991

0.58%

13,705

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	13,705	$10,991	100.0%	Defined

Persistent Asset Partners Ltd

$9,214

0.48%

11,490

XTX Topco Ltd

$8,473

0.45%

10,565

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	10,565	$8,473	100.0%	Defined

BlackRock, Inc.

$5,751

0.30%

7,173

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	71	$56	1.0%	Sole
BlackRock Fund Advisors	289	$231	4.0%	Sole
BlackRock Institutional Trust Company, N.A.	6,813	$5,464	95.0%	Sole

Tower Research Capital LLC (TRC)

$2,879

0.15%

3,590

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	3,590	$2,879	100.0%	Defined

GROUP ONE TRADING LLC

$462

0.02%

577

BARCLAYS PLC

$379

0.02%

473

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS CAPITAL INC.	473	$379	100.0%	Defined

OSAIC HOLDINGS, INC.

$236

0.01%

295

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	295	$236	100.0%	Defined

WealthCollab, LLC

$126

0.01%

158

FMR LLC

$36

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STRATEGIC ADVISERS LLC	45	$36	100.0%	Defined

Integrated Wealth Concepts LLC

$36

0.00%

SBI Securities Co., Ltd.

$12

0.00%

UBS Group AG

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	3	$2	100.0%	Defined

Key facts CIK 1781983 CUSIP 03836J201 13F (30d) 28 filings 28 filers Visit website Investor relations