FLNA · Filana Therapeutics, Inc.

The purchase reported in column 4 is a weighted average price. The shares were purchased in multiple open market transactions at prices ranging from $2.74 to $2.80 per share. The reporting person undertakes to provide to Cassava, any security holder of Cassava or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each price within the range set forth in this footnote.

The purchase reported in column 4 is a weighted average price. The shares were purchased in multiple open market transactions at prices ranging from $2.73 to $2.75 per share. The reporting person undertakes to provide to Cassava, any security holder of Cassava or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each price within the range set forth in this footnote.

The stock option vests over three (3) years at a rate of 1/36th each month.

The purchase reported in column 4 is a weighted average price. The shares were purchased in multiple open market transactions at prices ranging from $2.27 to $2.29 per share. The reporting person undertakes to provide to Cassava, any security holder of Cassava or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each price within the range set forth in this footnote.

Form 4 represents grant pursuant to the Amended Non-employee Director Compensation Program approved by stockholders on May 23, 2025. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Amended Non-employee Director Compensation Program approved by stockholders on May 23, 2025. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Amended Non-employee Director Compensation Program approved by stockholders on May 23, 2025. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Amended Non-employee Director Compensation Program approved by stockholders on May 23, 2025. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Amended Non-employee Director Compensation Program approved by stockholders on May 23, 2025. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Amended Non-employee Director Compensation Program approved by stockholders on May 23, 2025. Stock options vest over a one (1) year period at a rate of 1/12 per month.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on April 17, 2026.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on April 17, 2026.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on April 17, 2026.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on April 17, 2026.

1. The sale reported in column 4 is a weighted average price. The shares were sold in multiple open market transactions at prices ranging from $3.81 to $3.89 per share. The reporting person undertakes to provide to Cassava, any security holder of Cassava or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on November 18, 2025.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on November 18, 2025.

The stock option vests in four equal annual installments (25% each year) with the initial 25% vesting on July 15, 2025.

The stock option vests over 2 years, with 50% cliff vesting 1-year after grant date and the remaining 50% cliff vesting 2-years after grant date.

The stock option vests over 2 years, with 50% cliff vesting 1-year after grant date and the remaining 50% cliff vesting 2-years after grant date.

The stock option vests over 2 years, with 50% cliff vesting 1-year after grant date and the remaining 50% cliff vesting 2-years after grant date.

The stock option vests over four (4) years at a rate of 1/48th each full month.

The stock option vests over four (4) years at a rate of 1/48th each full month.

The stock option vests over four (4) years at a rate of 1/48th each full month.

The stock option vests over four (4) years at a rate of 1/48th each full month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents grant pursuant to the Non-employee Director Compensation Program approved by stockholders on May 4, 2023. Stock options vest over a one (1) year period at a rate of 1/12 per month.

Form 4 represents exercise of common stock warrants received on January 3, 2024 for cash. Holder received one and one-half shares of common stock for each common stock warrant exercised.

Form 4 represents exercise of common stock warrants received on January 3, 2024 for cash. Holder received one and one-half shares of common stock for each common stock warrant exercised.

Form 4 represents exercise for cash of common stock warrants received on January 3, 2024. Holder received one and one-half shares of common stock for each common stock warrant exercised.