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SDGR · Schrodinger, Inc.

Track SDGR — free
$27.20 -1.70 (-5.88%) At close · Oct 7
Market Cap
$2.16B
Shares
74.81M
Volume · Oct 7 4.56M Avg daily vol (3M) 1.68M

Price & Indicators

Drag to pan · scroll to zoom
20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$28.90 Open$32.99 Day$28.56–33.78 52W close$11.07–32.60 Avg vol 30d2.4M Short int11.2M · 14.9% float · 8.7d Short vol41% Last earningsAug 5, 2026 DataFeb 2020–Oct 2026 Filing10-Q · Aug 5

Up next

Next earnings call
Nov 5, 2026 Est · unconfirmed · in 4 wks
filed Aug 5, 2026
call held Aug 5, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
—
Trailing 12 months
Net income (TTM)
—
Trailing 12 months
Revenue growth YoY
—
Year over year
Operating margin
—
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
—
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
—
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
—
Year over year · more shares
Price change (1Y)
+35.7%
Trailing year
Short interest
14.9%
Latest settlement · 8.7 days to cover
View all 115 metrics

AI Brief

Q2 FY26 earnings call · Aug 5, 2026
Q2 FY26

TL;DR. Schrödinger delivered 27% Q2 ACV growth to $29.6M, launched its Bunsen AI co-scientist with a new BMS agreement, raised full-year drug discovery revenue guidance to $65-75M on a $10M Ajax milestone, and swung to a $6M GAAP net income from a $43M loss, while reaffirmed ACV guidance of $218-228M continues to imply 10-15% growth.

Bullish
  • + Q2 ACV grew 27% to $29.6M, with ex-contribution ACV up 23% at the upper end of expectations
  • + Drug discovery revenue jumped to $23M from $13.9M on a $10M Ajax milestone and full-year guidance raised to $65-75M from $55-65M
  • + Q2 swung to $6M GAAP net income from a $43M loss, aided by a $48.9M gain from Lilly's acquisition of Ajax
  • + Launched Bunsen AI co-scientist in early access and signed a strategic software agreement with Bristol-Myers Squibb expanding platform deployment
Bearish
  • − Software revenue declined 10% to $32.5M and software gross margin compressed to 71% from 76% due to the planned accelerated hosted transition
  • − Contribution revenue fell to $3.4M from $4.8M as initial Gates Foundation predictive toxicology funding was completed
  • − Full-year ACV guidance of $218-228M was reiterated, implying just 10-15% growth and a continued drag from hosted mix shift

AI-generated from the earnings call and 8-K · may contain errors · not investment advice

Equibles Rating

blended score · not investment advice
Overall
Buy
SellHoldBuy
Technical Neutral Momentum Very Strong Sentiment Bearish Fundamentals Excellent Quant / Vol Very High
Market backdrop VIX 15 · calm Equity put/call 0.57
Technical
price trend
Neutral
50 / 200-day cross No cross
Price vs 200-day avg +80%
above
Price vs 50-day avg +32%
above
RSI (14) 58
neutral
MACD trend Negative
52-week position 83%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Strong
1-month return +44%
trailing
6-month return +133%
trailing
YTD return +62%
this year
Relative strength +122%
vs S&P · 6-mo
Sentiment
smart money
Bearish
Trend (MA cross) No cross
50d $22 › 200d $16 — 50d above 200d
Institutional flow Distributing
2 of 233 funds reported for Sep 30 · net -701 sh shares
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
14.93% of float · ▲ +0.7% MoM · 8.7 days cover
Volume signal Reversal watch
High volume on a down day — possible exhaustion
Institution breadth Steady
233 holders — mid 3-yr range
Squeeze score 80
high risk · 0–100
Fundamentals
Excellent
Revenue growth +23%
Y/Y
Gross margin 56%
contracting
EPS growth +45%
Y/Y
Free cash flow $12.5M
Quant / Vol
risk profile
Very High
Volatility 64%
annualized · 1-yr
Max drawdown −51%
past year
ATR 7.5%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Beat or met 2 of last 2
Latest guidance · from the 8-K filed Aug 5, 2026
ACV · fiscal year ending December 31, 2026 Initiated $218M – $228M
Drug discovery revenue · fiscal year ending December 31, 2026 Initiated $65M – $75M
Prior guidance period ended · from the 8-K filed Aug 5, 2026
ACV excluding contribution ACV · third quarter of 2026 $41M – $45M
Guided vs delivered · last 2 settled
Total revenue fiscal year ending December 31, 2022
guided $167M – $175M
$180.96M Beat +5.8%
Total revenue full-year 2021
guided $124M – $134M
$137.93M Beat +6.9%

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Neutral
1 · 4 · 2
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+80% Bullish
Price vs 50-day avg
+32% Bullish
RSI (14)
58 Neutral
MACD trend
Negative Bearish
52-week position
83% Neutral
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bearish · 2 of 6
Trend (MA cross) No cross
50d $22 › 200d $16 — 50d above 200d
Institutional flow Distributing
2 of 233 funds reported for Sep 30 · net -701 sh shares
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
14.93% of float · ▲ +0.7% MoM · 8.7 days cover
Volume signal Reversal watch
High volume on a down day — possible exhaustion
Institution breadth Steady
233 holders — mid 3-yr range
Price context
position in its 52-week range
Range low $11 Now $29 · 83% Range high $33
vs 200-day avg +80% vs 50-day avg +32%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
Software gross margin 71% Q2 2026 —

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Health Information Services — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SDGR
Schrodinger, Inc.
this stock
$2.16B +61.6% +23.3% — 14.9%
VEEV
Veeva Systems Inc
$45.44B +27.0% +28.1% 45.9 3.1%
TEM
Tempus AI, Inc.
$15.34B +21.9% +83.4% — 15.6%
PMDIY
Pro Medicus Ltd./ADR
$12.20B -29.7% — — 0.0%
BTSG
BrightSpring Health Services, Inc.
$11.02B +70.2% +28.2% 33.8 5.1%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Reducing
Holders
233
% held
87.8%
Reported
2 of 233
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
200
View
Short & Settlement
Short Interest Rising
Shares short
11.2M
Days to cover
8.7d
Change
+80.1K sh
View
Short Volume
Short vol %
41%
As of
Oct 7, 2026
Short Total
View
Fails to Deliver
FTD shares
2.0K
Value
$39.2K
As of
Sep 9, 2026
View
Off-Exchange
Off-exchange %
43.2%
Week of
Aug 31, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$255.9M
Net income (FY)
$-103.3M
EPS diluted
$-1.41
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Sep 14, 2026
This year
13
View
Proposed Sales
Value
$756.2K
Shares
31.6K
Filed
Sep 17, 2026
View
Earnings & Events
Webcasts
Last webcast
Sep 14, 2026
View
Investor Relations
Latest news
Schrödinger Reports Inducement Gr…
Published
Sep 17, 2026
View

Performance

5D 20D 120D MTD YTD
SDGR -4.7% +44.3% +133.1% -6.9% +61.6%
SPY +2.0% +1.7% +11.3% +2.2% +14.3%
vs SPY -6.7% +42.6% +121.8% -9.1% +47.4%
Key facts CIK 1490978 CUSIP 80810D103 13F (30d) 6 filings 6 filers Visit website Investor relations