SEPN · Septerna, Inc.
Market Cap
$1.76B
Shares
46.68M
SEPN metrics
63 of 114 screener metrics currently available.
Market overview
2 metricsShare price
$37.50
Market cap
$1.76B
Price action
19 metricsPrice change (1W)
-8.8%
Price change (30D)
+7.7%
Price change (3M)
+25.9%
Price change (6M)
+33.9%
Price change (YTD)
+35.2%
Price change (1Y)
+211.4%
Trailing year
Price change (5Y)
—
52-week high
$48.19
52-week low
$12.34
Change from 52-week high
-21.8%
Change from 52-week low
+205.3%
Annualized volatility
69.2%
Beta
1.2
RSI (14D)
43.8
Price vs SMA 50
+0.7%
Price vs SMA 200
+27.9%
Avg volume (3M)
444,133
Relative volume
0.6
Average dollar volume
$16.64M
Company
3 metricsSector
Healthcare
Industry
Biotechnology
Shares outstanding
46.68M
Valuation
12 metricsP / E (TTM)
—
Trailing earnings
PEG ratio
—
EV / revenue
—
EV / EBITDA
—
EV / EBIT
—
P / sales
17.8×
reciprocal yield 5.6%
P / book
4.5
reciprocal yield 22.0%
FCF yield
6.0%
TTM · current market cap
Buyback yield
—
P / FCF
16.7
reciprocal yield 6.0%
P / operating cash flow
16.6
reciprocal yield 6.0%
Earnings yield
-1.4%
Historical valuation
8 metricsP / E historical average (3Y)
—
P / E historical average (5Y)
—
EV / revenue historical average (3Y)
—
EV / revenue historical average (5Y)
—
EV / EBIT historical average (3Y)
—
EV / EBIT historical average (5Y)
—
EV / EBITDA historical average (3Y)
—
EV / EBITDA historical average (5Y)
—
Dividends & buybacks
7 metricsDividend yield
—
Trailing 12 months
Payout ratio
—
Shareholder yield
—
Dividend / share (TTM)
—
Dividend growth YoY
—
Dividend growth streak
—
Last ex-dividend
—
Earnings calendar
2 metricsNext earnings
—
Last earnings
2026-03-02
Profitability
9 metricsGross margin
—
Operating margin
-44.0%
Trailing 12 months
Net margin
-24.5%
Gross profit (TTM)
—
Operating profit (TTM)
−$43.55M
Net income (TTM)
−$24.24M
Trailing 12 months
Diluted EPS (TTM)
$-0.53
FCF margin
106.3%
Effective tax rate
—
Growth
11 metricsRevenue growth YoY
+22,375.6%
Year over year
Net income growth YoY
—
Revenue (TTM)
$98.88M
Trailing 12 months
EPS growth YoY
—
Shares change YoY
+2.0%
Year over year · more shares
Revenue CAGR (3Y)
—
Revenue CAGR (5Y)
—
EPS CAGR (3Y)
—
EPS CAGR (5Y)
—
FCF CAGR (3Y)
—
FCF CAGR (5Y)
—
Quality
14 metricsReturn on equity
-6.3%
Return on assets
-4.3%
Debt / equity
—
Current ratio
5.0
EBITDA (TTM)
−$41.95M
Free cash flow (TTM)
$105.10M
Quick ratio
5.0
Interest coverage
—
Net debt / EBITDA
—
Return on invested capital
—
Trailing 12 months
Net cash
$372.32M
Latest balance sheet
Cash & equivalents
$84.66M
Total assets
$566.74M
Total debt
—
Cash flow & spend
7 metricsOperating cash flow (TTM)
$106.01M
Capital expenditures (TTM)
$910,000
R&D (TTM)
$120.79M
SG&A (TTM)
—
Stock compensation (TTM)
$16.28M
R&D / revenue
122.2%
Stock compensation / revenue
16.5%
Ownership (13F)
3 metrics13F filers
157
13F filer change QoQ
+32
Institutional ownership
104.3%
Short interest
3 metricsShort interest
6.2%
Latest settlement · 5.1 days to cover
Days to cover
5.1d
Short-squeeze score
55 / 100
Insider activity
2 metricsNet insider buying (90D)
−$73.15M
Insider-sentiment score
18 / 100
Risk flags
1 metricsGoing concern
—
Key facts
CIK
1984086
CUSIP
81734D104
13F (30d)
143 filings
138 filers
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Investor relations