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SEPN · Septerna, Inc. · Metrics

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$39.35 +2.97 (+8.16%) At close · Oct 20
Russell 2000 member Rebalance outlook locked
Market Cap
$1.84B
Shares
46.68M
Volume · Oct 20 418.32K Avg daily vol (3M) 385.09K

SEPN metrics

83 of 122 screener metrics currently available.

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Market overview

2 metrics
Share price
$39.35
Market cap
$1.84B

Price action

20 metrics
Price change (1W)
+8.1%
Price change (30D)
+2.1%
Price change (3M)
+16.8%
Price change (6M)
+52.5%
Price change (YTD)
+41.1%
Price change (1Y)
+75.4%
Trailing year
Price change (5Y)
—
52-week high
$48.19
52-week low
$18.10
Change from 52-week high
-18.3%
Change from 52-week low
+117.4%
Annualized volatility
67.2%
Annualized volatility (3M)
66.6%
Beta
1.0
RSI (14D)
56.2
Price vs SMA 50
+0.1%
Price vs SMA 200
+25.3%
Avg volume (3M)
385,088
Relative volume
1.1
Average dollar volume
$15.20M

Company

3 metrics
Sector
Healthcare
Industry
Biotechnology
Shares outstanding
46.68M

Valuation

12 metrics
P / E (TTM)
—
Trailing earnings
PEG ratio
—
EV / revenue
13.4×
reciprocal yield 7.5%
EV / EBITDA
—
EV / EBIT
—
P / sales
17.2×
reciprocal yield 5.8%
P / book
4.4
reciprocal yield 22.8%
FCF yield
6.2%
TTM · current market cap
Buyback yield
—
P / FCF
16.2
reciprocal yield 6.2%
P / operating cash flow
16.0
reciprocal yield 6.2%
Earnings yield
-1.4%

Historical valuation

8 metrics
P / E historical average (3Y)
—
P / E historical average (5Y)
—
EV / revenue historical average (3Y)
72.2×
reciprocal yield 1.4%
EV / revenue historical average (5Y)
72.2×
reciprocal yield 1.4%
EV / EBIT historical average (3Y)
—
EV / EBIT historical average (5Y)
—
EV / EBITDA historical average (3Y)
—
EV / EBITDA historical average (5Y)
—

Dividends & buybacks

7 metrics
Dividend yield
—
Trailing 12 months
Payout ratio
—
Shareholder yield
—
Dividend / share (TTM)
—
Dividend growth YoY
—
Dividend growth streak
—
Last ex-dividend
—

Earnings calendar

2 metrics
Next earnings
—
Last earnings
2026-03-02

Profitability

9 metrics
Gross margin
—
Operating margin
-44.0%
Trailing 12 months
Net margin
-24.5%
Gross profit (TTM)
—
Operating profit (TTM)
−$43.55M
Net income (TTM)
−$24.24M
Trailing 12 months
Diluted EPS (TTM)
$-0.53
FCF margin
106.3%
Effective tax rate
—

Per share

11 metrics
Revenue per diluted share (TTM)
$2.21
Gross profit per diluted share (TTM)
—
Operating profit per diluted share (TTM)
$-0.98
EBITDA per diluted share (TTM)
$-0.95
Net income per diluted share (TTM)
$-0.55
Operating cash flow per diluted share (TTM)
$2.29
Free cash flow per diluted share (TTM)
$2.27
Capital expenditures per diluted share (TTM)
$0.02
R&D per diluted share (TTM)
$2.71
Stock compensation per diluted share (TTM)
$0.36
Book value per share
$8.52

Growth

11 metrics
Revenue growth YoY
+22,375.6%
Year over year
Net income growth YoY
—
Revenue (TTM)
$98.88M
Trailing 12 months
EPS growth YoY
—
Shares change YoY
+2.0%
Year over year · more shares
Revenue CAGR (3Y)
—
Revenue CAGR (5Y)
—
EPS CAGR (3Y)
—
EPS CAGR (5Y)
—
FCF CAGR (3Y)
—
FCF CAGR (5Y)
—

Quality

14 metrics
Return on equity
-6.3%
Return on assets
-4.3%
Debt / equity
0.0
Current ratio
5.0
EBITDA (TTM)
−$41.95M
Free cash flow (TTM)
$105.10M
Quick ratio
5.0
Interest coverage
—
Net debt / EBITDA
—
Return on invested capital
—
Trailing 12 months
Net cash
$372.32M
Latest balance sheet
Cash & equivalents
$84.66M
Total assets
$566.74M
Total debt
$0

Cash flow & spend

7 metrics
Operating cash flow (TTM)
$106.01M
Capital expenditures (TTM)
$910,000
R&D (TTM)
$120.79M
SG&A (TTM)
—
Stock compensation (TTM)
$16.28M
R&D / revenue
122.2%
Stock compensation / revenue
16.5%

Ownership (13F)

9 metrics
13F filers
156
13F filer change QoQ
+31
Institutional ownership
104.3%
Conviction holders (share of 13F filers)
2.6%
Crowding (high-turnover and private-fund holders)
—
Private-fund adviser ownership
—
Active holders' share change QoQ
+3.9%
Holder tenure
6.1
Price vs estimated holder cost
+48.4%

Ownership (registered funds)

1 metrics
Index-fund ownership
7.8%

Short interest

3 metrics
Short interest
6.6%
Latest settlement · 8.8 days to cover
Days to cover
8.8d
Short-squeeze score
66 / 100

Insider activity

2 metrics
Net insider buying (90D)
−$64.94M
Insider-sentiment score
17 / 100

Risk flags

1 metrics
Going concern
—
Key facts CIK 1984086 CUSIP 81734D104 13F (30d) 7 filings 7 filers Visit website Investor relations