ACIU · AC Immune SA

$2.93 +0.09 (+2.99%)

Market Cap

$282.37M

99.43M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 43

Total Value: $58,593,721

Total Shares: 24,621,219

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 43 13F filers · Δ vs Mar 31, 2026

Top Holder

80.5%

+2.7 pts

Top 5

93.3%

+3.9 pts

Top 10

97.8%

+1.9 pts

HHI

6,531

Highly concentrated+429

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: -4

Institutional value: -16.4%

Shares held: -3.3%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large RENAISSANCE TECHNOLOGIES LLC	+215,760	840,127
Mega TWO SIGMA INVESTMENTS, LP	+63,734	102,825
Mega MORGAN STANLEY	+42,562	131,815
Mid Jump Financial, LLC	+12,939	24,064
Mega BARCLAYS PLC	+1,487	7,278

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	−172,705	232,953
Mega DIMENSIONAL FUND ADVISORS LP	−50,083	340,082
Mega CITADEL ADVISORS LLC	−44,827	253,406
Mega JANE STREET GROUP, LLC	−38,221	19,475
Mega MILLENNIUM MANAGEMENT LLC	−19,063	773,594

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega Qube Research & Technologies Ltd	92,351	$219,795
Small Verdad Advisers, LP	16,300	$38,794
Large Quadrature Capital Ltd	12,991	$30,918
Small AXQ CAPITAL, LP	10,398	$24,747
Mega SG Americas Securities, LLC	10,327	$24,578

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Large Point72 Asset Management, L.P.	293,200	$806,300
Mega NORTHERN TRUST CORP	278,513	$765,910
Large MARSHALL WACE, LLP	131,458	$361,509
Micro Dauntless Investment Group, LLC	107,489	$295,594
Large ACADIAN ASSET MANAGEMENT LLC	96,907	$266,494

Filter: New 6 Increased 11 Reduced 15 Sold out 10 Unchanged 11

Showing 47 of 47

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BVF INC/IL

$47,177,397

80.52%

19,822,436

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BVF PARTNERS L P/IL	19,822,436	$47,177,397	100.0%	Defined

WELLS FARGO & COMPANY/MN

$2,389,617

4.08%

1,004,041

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	1,000	$2,380	0.1%	Defined
WELLS FARGO CLEARING SERVICES, LLC	1,003,041	$2,387,237	99.9%	Defined

RENAISSANCE TECHNOLOGIES LLC

$1,999,502

3.41%

840,127

MILLENNIUM MANAGEMENT LLC

$1,841,153

3.14%

773,594

BlackRock, Inc.

$1,235,870

2.11%

519,274

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BlackRock Fund Advisors	441,181	$1,050,010	85.0%	Sole
BlackRock Institutional Trust Company, N.A.	4,018	$9,562	0.8%	Sole
BlackRock Asset Management Ireland Ltd	74,075	$176,298	14.3%	Sole

DIMENSIONAL FUND ADVISORS LP

$809,394

1.38%

340,082

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	9,822	$23,376	2.9%	Defined
DFA Australia Ltd.	8,501	$20,232	2.5%	Defined
Dimensional Ireland Ltd	56,306	$134,008	16.6%	Defined
Held directly	265,453	$631,778	78.1%	Sole

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

$554,428

0.95%

232,953

CITADEL ADVISORS LLC

$494,101

0.84%

207,606

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	7,223	$17,190	3.5%	Defined
Held directly	200,383	$476,911	96.5%	Defined

MORGAN STANLEY

$313,718

0.54%

131,815

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO. LLC	23	$54	0.0%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	95,679	$227,716	72.6%	Defined
MORGAN STANLEY SMITH BARNEY LLC	35,698	$84,961	27.1%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	415	$987	0.3%	Defined

TWO SIGMA INVESTMENTS, LP

$244,723

0.42%

102,825

Qube Research & Technologies Ltd

$219,795

0.38%

92,351

UBS Group AG

$203,760

0.35%

85,614

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	6,000	$14,280	7.0%	Defined
UBS AG	66,402	$158,036	77.6%	Defined
UBS Securities LLC	13,212	$31,444	15.4%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$166,362

0.28%

69,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	69,900	$166,362	100.0%	Other

GEODE CAPITAL MANAGEMENT, LLC

$147,212

0.25%

61,854

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$127,018

0.22%

53,369

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	53,369	$127,018	100.0%	Other

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$85,204

0.15%

35,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	35,800	$85,204	100.0%	Other

CITADEL ADVISORS LLC

$81,634

0.14%

34,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	34,300	$81,634	100.0%	Defined

Jump Financial, LLC

$57,272

0.10%

24,064

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Leap GP LLC joint	24,064	$57,272	100.0%	Defined

JANE STREET GROUP, LLC

$46,350

0.08%

19,475

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	19,475	$46,350	100.0%	Defined

Verdad Advisers, LP

$38,794

0.07%

16,300

China Universal Asset Management Co., Ltd.

$38,548

0.07%

16,197

GOLDMAN SACHS GROUP INC

$34,502

0.06%

14,497

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	14,497	$34,502	100.0%	Defined

Quadrature Capital Ltd

$30,918

0.05%

12,991

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	12,991	$30,918	100.0%	Other

CITADEL ADVISORS LLC

$27,370

0.05%

11,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	11,500	$27,370	100.0%	Defined

AXQ CAPITAL, LP

$24,747

0.04%

10,398

SG Americas Securities, LLC

$24,578

0.04%

10,327

Quinn Opportunity Partners LLC

$24,038

0.04%

10,100

Silverberg Bernstein Capital Management LLC

$23,800

0.04%

10,000

EFG International AG

$23,562

0.04%

9,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Cite Gestion SA	9,900	$23,562	100.0%	Defined

JPMORGAN CHASE & CO

$18,559

0.03%

7,798

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Securities plc	7,798	$18,559	100.0%	Defined

BARCLAYS PLC

$17,321

0.03%

7,278

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	7,278	$17,321	100.0%	Defined

Banque Cantonale Vaudoise

$16,709

0.03%

7,021

Mirae Asset Global Investments Co., Ltd.

$10,833

0.02%

4,552

Tower Research Capital LLC (TRC)

$9,760

0.02%

4,101

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Tower Research Capital Investments LLC	24	$57	0.6%	Other
Latour Trading LLC (Latour)	4,077	$9,703	99.4%	Defined

CITIGROUP INC

$9,548

0.02%

4,012

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	4,012	$9,548	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$6,423

0.01%

2,699

GF FUND MANAGEMENT CO. LTD.

$4,959

0.01%

2,084

ROYAL BANK OF CANADA

$3,066

0.01%

1,289

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Capital Markets, LLC	428	$1,018	33.2%	Defined
RBC Dominion Securities Inc.	760	$1,808	59.0%	Defined
Held directly	101	$240	7.8%	Sole

SBI Securities Co., Ltd.

$2,848

0.00%

1,197

Activest Wealth Management

$2,380

0.00%

1,000

Rockefeller Capital Management L.P.

$2,380

0.00%

1,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER FINANCIAL LLC	1,000	$2,380	100.0%	Defined

PNC FINANCIAL SERVICES GROUP, INC.

$2,380

0.00%

1,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	1,000	$2,380	100.0%	Defined

OSAIC HOLDINGS, INC.

$523

0.00%

220

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	220	$523	100.0%	Defined

Strengthening Families & Communities, LLC

$476

0.00%

200

Farther Finance Advisors, LLC

$102

0.00%

Caitong International Asset Management Co., Ltd

$83

0.00%

Forum Finance Group S.A.

0.00%

2,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST GLOBAL INVESTMENTS LTD	278,513	$765,910	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	131,458	$361,509	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	96,907	$266,494	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	17,437	$47,951	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	14,304	$39,336	100.0%	Defined

Key facts CIK 1651625 CUSIP H00263105 13F (30d) 36 filings 36 filers Visit website Investor relations