ANVS · Annovis Bio, Inc.

$1.82 +0.03 (+1.68%) At close · Aug 21

Market Cap

$76.27M

42.61M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 63

Total Value: $22,459,260

Total Shares: 12,074,886

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 63 13F filers · Δ vs Mar 31, 2026

Top Holder

19.9%

−2.7 pts

Top 5

68.3%

+0.2 pts

Top 10

88.3%

+5.5 pts

HHI

1,103

Broadly held−43

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +5

Institutional value: +92.0%

Shares held: +130.1%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega VANGUARD CAPITAL MANAGEMENT LLC	+774,941	1,647,322
Large MARSHALL WACE, LLP	+654,840	1,842,339
Large RENAISSANCE TECHNOLOGIES LLC	+654,600	1,002,200
Mega CITADEL ADVISORS LLC	+401,582	506,482
Mega BlackRock, Inc.	+110,323	249,856

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega NORTHERN TRUST CORP	−73,660	68,070
Mega TWO SIGMA INVESTMENTS, LP	−48,088	579,571
Mega JANE STREET GROUP, LLC	−27,800	58,900
Mega UBS Group AG	−9,763	11,775
Mega MORGAN STANLEY	−5,392	341

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Micro Empery Asset Management, LP	2,401,476	$4,466,745
Large TUDOR INVESTMENT CORP ET AL	1,357,134	$2,524,269
Large Caption Management, LLC	474,900	$883,314
Large Quadrature Capital Ltd	90,884	$169,044
Small Headlands Technologies LLC	48,071	$89,412

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mid Merit Financial Group, LLC	81,316	$181,334
Mid GROUP ONE TRADING LLC	69,663	$155,348
Mid XTX Topco Ltd	24,580	$54,813
Large HRT FINANCIAL LP	21,187	$47,247
Small Koshinski Asset Management, Inc.	15,028	$33,512

Filter: New 16 Increased 20 Reduced 6 Sold out 11 Unchanged 21

Showing 69 of 69

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Empery Asset Management, LP

$4,466,745

19.89%

2,401,476

MARSHALL WACE, LLP

$3,426,749

15.26%

1,842,339

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	1,842,339	$3,426,749	100.0%	Other

VANGUARD CAPITAL MANAGEMENT LLC

$3,064,018

13.64%

1,647,322

TUDOR INVESTMENT CORP ET AL

$2,524,269

11.24%

1,357,134

RENAISSANCE TECHNOLOGIES LLC

$1,864,092

8.30%

1,002,200

TWO SIGMA INVESTMENTS, LP

$1,078,002

4.80%

579,571

Caption Management, LLC

$883,314

3.93%

474,900

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$531,774

2.37%

285,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	285,900	$531,774	100.0%	Other

GEODE CAPITAL MANAGEMENT, LLC

$527,899

2.35%

283,817

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	49,925	$92,860	17.6%	Defined
Held directly	233,892	$435,039	82.4%	Defined

BlackRock, Inc.

$464,731

2.07%

249,856

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BlackRock Investment Management, LLC	6,991	$13,003	2.8%	Sole
BlackRock Fund Advisors	103,332	$192,197	41.4%	Sole
BlackRock Institutional Trust Company, N.A.	139,533	$259,531	55.8%	Sole

CITADEL ADVISORS LLC

$453,247

2.02%

243,682

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	241,408	$449,018	99.1%	Defined
Held directly	2,274	$4,229	0.9%	Defined

VANGUARD FIDUCIARY TRUST CO

$330,205

1.47%

177,530

CITADEL ADVISORS LLC

$275,280

1.23%

148,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	148,000	$275,280	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$273,054

1.22%

146,804

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	126,058	$234,467	85.9%	Other
G1 EXECUTION SERVICES, LLC	20,746	$38,587	14.1%	Other

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$241,242

1.07%

129,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	129,700	$241,242	100.0%	Other

CITADEL ADVISORS LLC

$213,528

0.95%

114,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	114,800	$213,528	100.0%	Defined

Quadrature Capital Ltd

$169,044

0.75%

90,884

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	90,884	$169,044	100.0%	Other

STATE STREET CORP

$144,587

0.64%

77,735

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS TRUST COMPANY	77,735	$144,587	100.0%	Defined

NORTHERN TRUST CORP

$126,610

0.56%

68,070

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	68,070	$126,610	100.0%	Defined

First National Trust Co

$111,600

0.50%

60,000

Sherry Group, Inc.

$106,522

0.47%

57,270

GSA CAPITAL PARTNERS LLP

$92,821

0.41%

49,904

Greenwich Wealth Management LLC

$90,024

0.40%

48,400

Headlands Technologies LLC

$89,412

0.40%

48,071

JANE STREET GROUP, LLC

$79,050

0.35%

42,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	42,500	$79,050	100.0%	Defined

Wescott Financial Advisory Group, LLC

$77,389

0.34%

41,607

BRIDGEWAY CAPITAL MANAGEMENT, LLC

$70,079

0.31%

37,677

WELLS FARGO & COMPANY/MN

$56,370

0.25%

30,307

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	26,245	$48,815	86.6%	Defined
WELLS FARGO CLEARING SERVICES, LLC	4,062	$7,555	13.4%	Defined

Dakota Wealth Management

$53,940

0.24%

29,000

CWA Asset Management Group, LLC

$52,081

0.23%

28,001

MILLENNIUM MANAGEMENT LLC

$43,641

0.19%

23,463

Sterling Investment Advisors, Ltd.

$43,553

0.19%

23,416

Wealthspire Advisors, LLC

$37,200

0.17%

20,000

Robertson Stephens Wealth Management, LLC

$34,556

0.15%

18,579

GILL CAPITAL PARTNERS, LLC

$34,556

0.15%

18,579

JANE STREET GROUP, LLC

$30,504

0.14%

16,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	16,400	$30,504	100.0%	Defined

Quadcap Wealth Management, LLC

$29,964

0.13%

16,110

Bank of New York Mellon Corp

$28,784

0.13%

15,476

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
The Bank of New York Mellon	747	$1,389	4.8%	Defined
Newton Investment Management North America, LLC	14,728	$27,394	95.2%	Defined
Held directly	1	$1	0.0%	Defined

JPMORGAN CHASE & CO

$28,307

0.13%

15,219

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	319	$593	2.1%	Defined
J.P. Morgan Securities LLC	14,900	$27,714	97.9%	Defined

StoneX Group Inc.

$26,904

0.12%

14,465

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STONEX FINANCIAL INC.	14,465	$26,904	100.0%	Defined

UBS Group AG

$21,901

0.10%

11,775

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	633	$1,177	5.4%	Defined
UBS AG	2,664	$4,955	22.6%	Defined
UBS Securities LLC	8,478	$15,769	72.0%	Defined

Vanguard Global Advisers, LLC

$20,813

0.09%

11,190

Kestra Advisory Services, LLC

$19,716

0.09%

10,600

Gallacher Capital Management LLC

$18,600

0.08%

10,000

RKL Wealth Management LLC

$18,600

0.08%

10,000

Wilmington Savings Fund Society, FSB

$17,470

0.08%

9,393

Arax Advisory Partners

$12,090

0.05%

6,500

Gallacher Capital Management LLC

$10,611

0.05%

5,705

ROYAL BANK OF CANADA

$10,416

0.05%

5,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Private Counsel (USA) Inc.	5,600	$10,416	100.0%	Defined

Covestor Ltd

$8,619

0.04%

4,634

CoreCap Advisors, LLC

$3,907

0.02%

2,101

BARCLAYS PLC

$3,470

0.02%

1,866

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS CAPITAL INC.	1,866	$3,470	100.0%	Defined

Steward Partners Investment Advisory, LLC

$3,431

0.02%

1,845

SBI Securities Co., Ltd.

$2,877

0.01%

1,547

Keating Financial Advisory Services, Inc.

$2,012

0.01%

1,082

Rockefeller Capital Management L.P.

$1,860

0.01%

1,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER FINANCIAL LLC	1,000	$1,860	100.0%	Defined

DiNuzzo Private Wealth, Inc.

$1,860

0.01%

1,000

FMR LLC

$1,134

0.01%

610

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STRATEGIC ADVISERS LLC	610	$1,134	100.0%	Defined

BOKF, NA

$1,032

0.00%

555

PNC FINANCIAL SERVICES GROUP, INC.

$669

0.00%

360

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	360	$669	100.0%	Defined

MORGAN STANLEY

$634

0.00%

341

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO. LLC	141	$262	41.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	200	$372	58.7%	Defined

Larson Financial Group LLC

$558

0.00%

300

Rialto Wealth Management, LLC

$500

0.00%

269

OSAIC HOLDINGS, INC.

$390

0.00%

210

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	200	$372	95.4%	Defined
Osaic Advisory Services, LLC	10	$18	4.6%	Defined

IFP Advisors, Inc

$204

0.00%

110

Global Retirement Partners, LLC

$186

0.00%

100

NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO

$37

0.00%

Caitong International Asset Management Co., Ltd

$11

0.00%

CITIGROUP INC

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	3	$5	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	24,580	$54,813	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	944	$2,105	100.0%	Defined

Key facts CIK 1477845 CUSIP 03615A108 13F (30d) 59 filings 58 filers Visit website Investor relations