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IONS · Ionis Pharmaceuticals Inc · Short Interest

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$45.40 +1.02 (+2.30%)
Russell 1000 member Rebalance outlook locked
Market Cap
$7.38B
Shares
166.18M
Volume · Oct 20 2.49M Avg daily vol (3M) 3.28M

Shares sold short and not yet covered, reported twice monthly. Days to cover is the reported short position divided by average daily volume.

Pull short interest history through the short interest API or MCP →

IONS Latest Reported Short Interest

FINRA reported 22,508,744 IONS shares sold short as of the September 30, 2026 settlement date, an increase of 1,618,492 shares. Days to cover was 4.61 based on FINRA's reported average daily volume.

Official FINRA short-interest data · share counts are restated for subsequent splits of this listing

IONS Short Interest Forecast

Equibles' model estimates 21,751,980 shares sold short for the October 15, 2026 settlement, -3.4% versus the latest reported position, with a likely range of 19,532,506 to 24,084,261 shares. This model prediction uses FINRA data through October 15, 2026; FINRA's official release is expected October 26, 2026.

Model estimate

Expected Oct 15 short interest

as of Oct 15 Medium confidence 66% chance it falls
21,751,980 -3.4% vs reported
Likely range 19,532,506 to 24,084,261 The latest estimate appears in the chart below. Official release expected Oct 26. Methodology
Short Squeeze Score
65/100
Short interest 13.5% of shares — P93 Days to cover 4.6 — P67 Price vs VWAP -11.1% — P35 Short-volume trend -1.2% — P47 Short interest change +7.7% — P68 Worst FTD 0.01% of shares — P43

Positioning score 64.9 + catalyst boost 0 (total capped at 100). This is a screening index, not a probability of a squeeze.

Method and coverage limits

Factor percentiles compare eligible primary operating-company stocks reporting short interest at the latest settlement date (2026-09-30). The weighted mean uses short interest 30%, days to cover 20%, price vs VWAP 15%, short-volume trend 15%, short-interest change 10%, and fails-to-deliver 10%. Missing factors redistribute their weight; incomplete coverage is not evidence of low risk. Price, volume, and earnings boosts add 10 each, capped at 20.

Shares outstanding are not free float. Borrow fees, utilization, lendable supply, recalls, and dealer inventory are not measured. Short-sale volume does not measure the change in open shorts; fails to deliver are not a borrow-cost measurement; price vs VWAP does not establish short sellers' entry prices. Earnings can move prices in either direction.

The weights are judgment-based, not calibrated to future squeeze outcomes. The separate options assessment below does not change this universe ranking.

Options positioning & squeeze sensitivity

Nearest expiration after today within 30 calendar days; same-day expirations and later maturities are excluded.

No listed expiration after today falls within the next 30 calendar days.

Open interest has both a buyer and a seller; it does not reveal dealer hedge direction. Gross gamma sums both calls and puts without netting and uses a local 1% price-change approximation. It measures sensitivity, not predicted buying or a squeeze probability.

Assessment prepared 2026-10-20 22:01 UTC. Options model values may come from a cached snapshot; their original computation time is not supplied. Open interest has its own effective date.

1M 3M 6M 1Y 5Y All
Dimensions
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    • Short Interest History

    Settlement Date Current Position Previous Position Change Days to Cover
    2026-10-30 Scheduled
    FINRA publishes Nov 10
    		 — — — —
    2026-10-15 Scheduled
    FINRA publishes Oct 26
    		 — — — —
    2026-09-30 22,508,744 20,890,252 +1,618,492 4.61
    2026-09-15 20,890,252 20,924,638 -34,386 5.20
    2026-08-31 20,924,638 20,909,181 +15,457 9.18
    2026-08-14 20,909,181 21,466,123 -556,942 9.62
    2026-07-31 21,466,123 20,042,879 +1,423,244 6.35
    2026-07-15 20,042,879 17,425,020 +2,617,859 3.68
    2026-06-30 17,425,020 17,757,362 -332,342 7.33
    2026-06-15 17,757,362 16,986,466 +770,896 10.64
    2026-05-29 16,986,466 16,086,234 +900,232 9.98
    2026-05-15 16,086,234 16,279,706 -193,472 10.00
    2026-04-30 16,279,706 13,762,159 +2,517,547 8.04
    2026-04-15 13,762,159 14,330,826 -568,667 9.54
    2026-03-31 14,330,826 13,949,702 +381,124 5.93
    2026-03-13 13,949,702 15,323,236 -1,373,534 5.68
    2026-02-27 15,323,236 15,487,922 -164,686 6.91
    2026-02-13 15,487,922 15,537,729 -49,807 8.37
    2026-01-30 15,537,729 13,729,783 +1,807,946 5.82
    2026-01-15 13,729,783 14,885,370 -1,155,587 6.59
    2025-12-31 14,885,370 16,086,183 -1,200,813 9.49
    2025-12-15 16,086,183 15,626,208 +459,975 7.96
    2025-11-28 15,626,208 14,223,973 +1,402,235 5.95
    2025-11-14 14,223,973 12,661,274 +1,562,699 3.81
    2025-10-31 12,661,274 13,699,358 -1,038,084 6.61

    Full FINRA short interest reporting calendar

    Showing 1–23 of 23 settlements
    Key facts CIK 874015 CUSIP 462222100 13F (30d) 41 filings 40 filers Visit website Investor relations