ALLO · Allogene Therapeutics, Inc.
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AI Brief
Q2 FY26 earnings call · Aug 12, 2026TL;DR. Allogene's Q2 2026 was highlighted by FDA RMAT and Fast Track designations for cema-cel in 1L LBCL consolidation, accelerated ALPHA3 site activation to ~100 by year-end (six months ahead of plan), and brisk ALLO-329 enrollment with a Q4 2026 clinical update planned; cash runway extends into 2029, though the company posted a $42.7M net loss.
- + FDA granted RMAT and Fast Track designations for cema-cel as 1L consolidation therapy in July 2026 following review of the interim futility analysis.
- + ALPHA3 interim futility analysis showed a 41.6% absolute MRD clearance advantage for cema-cel vs observation with a favorable outpatient safety profile and no treatment-related serious adverse events.
- + ALPHA3 site activation target accelerated by six months; ~100 sites now expected active by year-end 2026 versus prior 80-site goal.
- + ALLO-329 RESOLUTION trial enrollment is brisk across dose escalation and lymphodepletion cohorts, with a clinical and translational update on track for Q4 2026.
- + Cash runway projected into 2029 supported by $423.6M in cash, cash equivalents and investments as of June 30, 2026.
- − Company reported a Q2 2026 net loss of $42.7M ($0.13 per share).
- − ALLO-316 TRAVERSE program has faced real safety challenges despite notable 31% confirmed ORR in CD70-high RCC.
AI-generated from the earnings call and 8-K · may contain errors · not investment advice
Equibles Rating
blended score · not investment adviceBlended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.
Guidance & track record
Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.
Technicals
trend & momentum for long-term holders SellIllustrative technical + ownership context — a signal mix, not investment advice.
Key metrics
Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.
Versus peers
Biotechnology — same industry group| Company | Mkt cap | YTD | Rev growth Y/Y | P/E | Short % shares |
|---|---|---|---|---|---|
|
ALLO
this stock
Allogene Therapeutics, Inc.
|
$563.15M | +16.8% | -100.0% | — | 17.3% |
|
VRTX
Vertex Pharmaceuticals Inc / Ma
|
$133.37B | +15.3% | +46.2% | 30.7 | 1.9% |
|
REGN
Regeneron Pharmaceuticals, Inc.
|
$81.13B | -1.8% | +20.8% | 19.5 | 2.5% |
|
MRNA
Moderna, Inc.
|
$79.40B | +553.0% | +4.3% | — | 8.2% |
|
CSLLY
Csl Ltd
|
$61.25B | — | — | — | 0.0% |
Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding
At a glance
key data from every sectionPerformance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| ALLO | -4.2% | -19.6% | -45.0% | -20.0% | +16.8% |
| SPY | -0.7% | +0.1% | +12.2% | -0.6% | +11.8% |
| vs SPY | -3.5% | -19.7% | -57.2% | -19.4% | +5.0% |